Dalan Bailey (0000-0002-5640-2266)

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Biography

Virologist: I am a Group Leader at The Pirbright Institute in the UK. My research has evolved from the study of neglected viral pathogens to the development of animal models and the study of human viruses and I have established myself as one of the leading young researchers in this area. I was recently awarded a prestigious MRC NIRG to launch a research program focused on human respiratory viruses and systems virology. My multidisciplinary and distinct research strategy combines in vivo models, recombinant virus technologies and proteomics with clinical research and emerging technologies such as transcriptomics to study the molecular and cellular basis of host-pathogen interactions, especially the antiviral responses of infected cells.

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The Pirbright Institute: Guildford, Surrey, GB

2017-10-02 to present | Group Leader

Employment

Dalan Bailey

https://orcid.org/0000-0002-5640-2266

Personal information

Biography

Activities

Employment (4)

The Pirbright Institute: Guildford, Surrey, GB

University of Birmingham: Birmingham, Birmingham, GB

The Pirbright Institute: Surrey, Surrey, GB

Imperial College London: London, London, GB

Education and qualifications (2)

Institute for Animal Health: Surrey, Surrey, GB

University of Warwick: Coventry, Coventry, GB

Funding (5)

A One Health approach to pan-valent morbillivirus vaccines

Innate immune restriction of enveloped virus exit

Disease Pathogenesis

Molecular and Systems Virology

Virus diversity and evolution

Works (38)

Respiratory syncytial virus sequesters NF-KB subunit p65 to cytoplasmic inclusion bodies to inhibit innate immune signalling

Morbilliviruses: Entry, Exit and Everything In-Between.

BST2/Tetherin Overexpression Modulates Morbillivirus Glycoprotein Production to Inhibit Cell-Cell Fusion.

Bacterial flagellin promotes viral entry via an NF-kB and Toll Like Receptor 5 dependent pathway.

Murine norovirus virulence factor 1 (VF1) protein contributes to viral fitness during persistent infection

Advances in diagnostics, vaccines and therapeutics for Nipah virus.

Viral infection enhances vomocytosis of intracellular fungi via Type I interferons

Structure-Guided Identification of a Nonhuman Morbillivirus with Zoonotic Potential.

Removal of the N-Glycosylation Sequon at Position N116 Located in p27 of the Respiratory Syncytial Virus Fusion Protein Elicits Enhanced Antibody Responses after DNA Immunization.

Targeting macrophage- and intestinal epithelial cell-specific microRNAs against norovirus restricts replication in vivo.

Future research to underpin successful peste des petits ruminants virus (PPRV) eradication.

The Measles Virus Receptor SLAMF1 Can Mediate Particle Endocytosis.

Human liver sinusoidal endothelial cells promote intracellular crawling of lymphocytes during recruitment: A new step in migration.

Norovirus Polymerase Fidelity Contributes to Viral Transmission In Vivo.

Serosurvey of peste des petits ruminants virus in small ruminants from different agro-ecological zones of Nigeria.

Identifying novel protein interactions: proteomic methods, optimisation approaches and data analysis pipelines.

Serological evidence of camel exposure to peste des petits ruminants virus (PPRV) in Nigeria.

The murine norovirus core subgenomic RNA promoter consists of a stable stem-loop that can direct accurate initiation of RNA synthesis.

Detection of protein-protein interactions using tandem affinity purification.

Norovirus translation requires an interaction between the C Terminus of the genome-linked viral protein VPg and eukaryotic translation initiation factor 4G.

Pathology caused by persistent murine norovirus infection.

Early events following experimental infection with Peste-Des-Petits ruminants virus suggest immune cell targeting.

Influence of genome-scale RNA structure disruption on the replication of murine norovirus--similar replication kinetics in cell culture but attenuation of viral fitness in vivo.

Characterization of ovine Nectin-4, a novel peste des petits ruminants virus receptor.

Identification of protein interacting partners using tandem affinity purification.

High-resolution functional profiling of the norovirus genome.

Development of a reverse-genetics system for murine norovirus 3: long-term persistence occurs in the caecum and colon.

A novel approach to generating morbillivirus vaccines: negatively marking the rinderpest vaccine.

Norovirus regulation of the innate immune response and apoptosis occurs via the product of the alternative open reading frame 4.

Polypyrimidine tract binding protein functions as a negative regulator of feline calicivirus translation.

Development of an optimized RNA-based murine norovirus reverse genetics system.

Functional Analysis of RNA Structures Present at the 3? Extremity of the Murine Norovirus Genome: the Variable Polypyrimidine Tract Plays a Role in Viral Virulence.

Feline calicivirus p32, p39 and p30 proteins localize to the endoplasmic reticulum to initiate replication complex formation.

Functional analysis of RNA structures present at the 3' extremity of the murine norovirus genome: the variable polypyrimidine tract plays a role in viral virulence.

Full genome sequences of two virulent strains of peste-des-petits ruminants virus, the Cote d'Ivoire 1989 and Nigeria 1976 strains.

Bioinformatic and functional analysis of RNA secondary structure elements among different genera of human and animal caliciviruses.

Reverse genetics for peste-des-petits-ruminants virus (PPRV): promoter and protein specificities.

Full genome sequence of peste des petits ruminants virus, a member of the Morbillivirus genus.