Personal information

Activities

Employment (3)

Fudan University School of Basic Medical Sciences: Shanghai, CN

2014-08-02 to present | Associate Professor (Department of Biochemistry and Molecular Biology)
Employment
Source: Self-asserted source
Si zhang

Fudan University School of Basic Medical Sciences: Shanghai, CN

2007-09-01 to 2014-08-01 | lecturer (Department of Biochemistry and Molecular Biology)
Employment
Source: Self-asserted source
Si zhang

Fudan University School of Basic Medical Sciences: Shanghai, CN

2000-09-01 to 2007-08-01 | Assistant Professor (Department of Biochemistry and Molecular Biology)
Employment
Source: Self-asserted source
Si zhang

Education and qualifications (3)

Shanghai Medical College, Fudan University: Shanghai, CN

2008-09-01 to 2012-07-01 | Ph.D. In Biochemistry and Molecular Biology
Education
Source: Self-asserted source
Si zhang

Shanghai Medical College, Fudan University: Shanghai, CN

2005-09-01 to 2008-07-01 | M.S. In Biochemistry and Molecular Biology
Education
Source: Self-asserted source
Si zhang

Anhui Medical College: Hefei, CN

1995-09-01 to 2000-07-01 | B.S. In Medicine
Education
Source: Self-asserted source
Si zhang

Works (50 of 60)

Items per page:
Page 1 of 2

Double-stranded DNA enhances platelet activation, thrombosis, and myocardial injury via cyclic GMP-AMP synthase

Cardiovascular Research
2024-09-20 | Journal article
Contributors: Wei Zhang; Yan Zhang; Liping Han; Tao Bo; Zhiyong Qi; Haoxuan Zhong; Huajie Xu; Liang Hu; She Chen; Si Zhang
Source: check_circle
Crossref

Inactivated whole-virion SARS-CoV-2 vaccines and long-term clinical outcomes in patients with coronary atherosclerosis disease in China: a prospective cohort study

Cardiovascular Research
2023-06-13 | Journal article
Contributors: Huajie Xu; Jiaojiao Zheng; Xin Zhao; Qi Zhou; Bing Fan; Hongyi Wu; Si Zhang; Junbo Ge
Source: check_circle
Crossref

Immunoglobulin superfamily 9 (IGSF9) is trans-activated by p53, inhibits breast cancer metastasis via FAK

Oncogene
2022-10-07 | Journal article
Contributors: Yaohua Li; Yiran Deng; Yannan Zhao; Wei Zhang; Si Zhang; Li Zhang; Biyun Wang; Yingying Xu; She Chen
Source: check_circle
Crossref

The long non-coding RNA DKFZp434J0226 regulates the alternative splicing process through phosphorylation of SF3B6 in PDAC

Molecular Medicine
2021-12 | Journal article
Contributors: Jinglei Li; Hanxing Tong; Dongping Li; Qiuyu Jiang; Yong Zhang; Wenqing Tang; Dayong Jin; She Chen; Xinyu Qin; Si Zhang et al.
Source: check_circle
Crossref

MRCKβ links Dasm1 to actin rearrangements to promote dendrite development

Journal of Biological Chemistry
2021-01 | Journal article
Contributors: Xiao-Xiao Wang; Si Zhang; Ping-Ping Dong; Yao-Hua Li; Li Zhang; Song-Hai Shi; Zhi-Qiang Yu; She Chen
Source: check_circle
Crossref

Clinicopathological and prognostic implications of vessels encapsulate tumor clusters with PD-L1 in intrahepatic cholangiocarcinoma patients

Translational Cancer Research
2020 | Journal article
EID:

2-s2.0-85085974696

Part of ISBN:

22196803 2218676X

Contributors: Tao, P.; Ma, L.; Xue, R.; Wang, H.; Zhang, S.
Source: Self-asserted source
Si zhang via Scopus - Elsevier

SARS-CoV-2 binds platelet ACE2 to enhance thrombosis in COVID-19

Journal of Hematology & Oncology
2020-12 | Journal article
Part of ISSN: 1756-8722
Source: Self-asserted source
Si zhang

Dampened VEPH1 activates mTORC1 signaling by weakening the TSC1/TSC2 association in hepatocellular carcinoma

Journal of Hepatology
2020-06 | Journal article
Part of ISSN: 0168-8278
Source: Self-asserted source
Si zhang
grade
Preferred source (of 2)‎

M2‐polarized tumor‐associated macrophages promote epithelial‐mesenchymal transition via activation of the AKT3/PRAS40 signaling pathway in intrahepatic cholangiocarcinoma

Journal of Cellular Biochemistry
2020-04 | Journal article
Part of ISSN: 1097-4644
Source: Self-asserted source
Si zhang
grade
Preferred source (of 2)‎

CD86+/CD206+ tumor-associated macrophages predict prognosis of patients with intrahepatic cholangiocarcinoma

PeerJ
2020-01-22 | Journal article
Part of ISSN: 2167-8359
Source: Self-asserted source
Si zhang
grade
Preferred source (of 2)‎

Benzene induces haematotoxicity by promoting deacetylation and autophagy

Journal of Cellular and Molecular Medicine
2019 | Journal article
EID:

2-s2.0-85056195984

Part of ISBN:

15821838

Contributors: Qian, S.; Han, Y.; Shi, Y.; Xu, W.; Zhu, Y.; Jiang, S.; Chen, Y.; Yu, Z.; Zhang, S.; Yang, Y. et al.
Source: Self-asserted source
Si zhang via Scopus - Elsevier

Exosomes isolated from CAPS1‑overexpressing colorectal cancer cells promote cell migration

Oncology Reports
2019 | Journal article
EID:

2-s2.0-85074480901

Part of ISBN:

17912431 1021335X

Contributors: Wu, B.; Sun, D.; Ma, L.; Deng, Y.; Zhang, S.; Dong, L.; Chen, S.
Source: Self-asserted source
Si zhang via Scopus - Elsevier

TREM2 acts as a tumor suppressor in hepatocellular carcinoma by targeting the PI3K/Akt/β-catenin pathway

Oncogenesis
2019 | Journal article
EID:

2-s2.0-85060753603

Part of ISBN:

21579024

Contributors: Tang, W.; Lv, B.; Yang, B.; Chen, Y.; Yuan, F.; Ma, L.; Chen, S.; Zhang, S.; Xia, J.
Source: Self-asserted source
Si zhang via Scopus - Elsevier

CAPS1 promotes colorectal cancer metastasis via Snail mediated epithelial mesenchymal transformation

Oncogene
2019-06 | Journal article
Part of ISSN: 0950-9232
Part of ISSN: 1476-5594
Source: Self-asserted source
Si zhang
grade
Preferred source (of 2)‎

Autophagy promotes aortic adventitial fibrosis via the IL-6/Jak1 signaling pathway in Takayasu's arteritis

Journal of Autoimmunity
2019-05 | Journal article
Part of ISSN: 0896-8411
Source: Self-asserted source
Si zhang
grade
Preferred source (of 2)‎

FXR Acts as a Metastasis Suppressor in Intrahepatic Cholangiocarcinoma by Inhibiting IL-6-Induced Epithelial-Mesenchymal Transition

Cellular Physiology and Biochemistry
2018 | Journal article
EID:

2-s2.0-85049871321

Part of ISBN:

14219778 10158987

Contributors: Lv, B.; Ma, L.; Tang, W.; Huang, P.; Yang, B.; Wang, L.; Chen, S.; Gao, Q.; Zhang, S.; Xia, J.
Source: Self-asserted source
Si zhang via Scopus - Elsevier

Pro-fibrotic effect of IL-6 via aortic adventitial fibroblasts indicates IL-6 as a treatment target in Takayasu arteritis

Clinical and Experimental Rheumatology
2018 | Journal article
EID:

2-s2.0-85042158205

Part of ISBN:

1593098X 0392856X

Contributors: Kong, X.; Ma, L.; Ji, Z.; Dong, Z.; Zhang, Z.; Hou, J.; Zhang, S.; Ma, L.; Jiang, L.
Source: Self-asserted source
Si zhang via Scopus - Elsevier

Response by Hu et al to Letters Regarding Article, "Platelets Express Activated P2Y <inf>12</inf> Receptor in Patients With Diabetes Mellitus"

Circulation
2018 | Journal article
EID:

2-s2.0-85065573928

Part of ISBN:

15244539

Contributors: Hu, L.; Qi, Z.; Zhang, S.; Luo, X.; Kunapuli, S.P.; Ye, H.; Ding, Z.
Source: Self-asserted source
Si zhang via Scopus - Elsevier

Smurf2, an E3 ubiquitin ligase, interacts with PDE4B and attenuates liver fibrosis through miR-132 mediated CTGF inhibition

Biochimica et Biophysica Acta - Molecular Cell Research
2018 | Journal article
EID:

2-s2.0-85034669941

Part of ISBN:

18792596 01674889

Contributors: Cai, Y.; Huang, G.; Ma, L.; Dong, L.; Chen, S.; Shen, X.; Zhang, S.; Xue, R.; Sun, D.; Zhang, S.
Source: Self-asserted source
Si zhang via Scopus - Elsevier

Dynamic network biomarker indicates pulmonary metastasis at the tipping point of hepatocellular carcinoma

Nature Communications
2018-12 | Journal article
Part of ISSN: 2041-1723
Source: Self-asserted source
Si zhang
grade
Preferred source (of 2)‎

Cholestasis-induced bile acid elevates estrogen level via farnesoid X receptor–mediated suppression of the estrogen sulfotransferase SULT1E1

Journal of Biological Chemistry
2018-08 | Journal article
Contributors: Xijun Liu; Ruyi Xue; Caiting Yang; Jianxin Gu; She Chen; Si Zhang
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Role of P2Y<inf>12</inf> receptor in thrombosis

Advances in Experimental Medicine and Biology
2017 | Book
EID:

2-s2.0-85000716012

Contributors: Zhang, Y.; Zhang, S.; Ding, Z.
Source: Self-asserted source
Si zhang via Scopus - Elsevier

Platelets Express Activated P2Y12Receptor in Patients With Diabetes Mellitus

Circulation
2017-08-29 | Journal article
Part of ISSN: 0009-7322
Part of ISSN: 1524-4539
Source: Self-asserted source
Si zhang
grade
Preferred source (of 2)‎

CAPS1 negatively regulates hepatocellular carcinoma development through alteration of exocytosis-associated tumor microenvironment

International Journal of Molecular Sciences
2016 | Journal article
EID:

2-s2.0-84989298208

Contributors: Xue, R.; Tang, W.; Dong, P.; Weng, S.; Ma, L.; Chen, S.; Liu, T.; Shen, X.; Huang, X.; Zhang, S. et al.
Source: Self-asserted source
Si zhang via Scopus - Elsevier

CD86<sup>+</sup>/CD206<sup>+</sup>, diametrically polarized tumor-associated macrophages, predict hepatocellular carcinoma patient prognosis

International Journal of Molecular Sciences
2016 | Journal article
EID:

2-s2.0-84959480217

Contributors: Dong, P.; Ma, L.; Liu, L.; Zhao, G.; Zhang, S.; Dong, L.; Xue, R.; Chen, S.
Source: Self-asserted source
Si zhang via Scopus - Elsevier

Overexpression of protein O-fucosyltransferase 1 accelerates hepatocellular carcinoma progression via the Notch signaling pathway

Biochemical and Biophysical Research Communications
2016 | Journal article
EID:

2-s2.0-84962091296

Contributors: Ma, L.; Dong, P.; Liu, L.; Gao, Q.; Duan, M.; Zhang, S.; Chen, S.; Xue, R.; Wang, X.
Source: Self-asserted source
Si zhang via Scopus - Elsevier

TSG-6 treatment promoted apoptosis in human fibroblasts of pathological scar

Cellular and Molecular Biology
2016 | Journal article
EID:

2-s2.0-84994888512

Contributors: Wang, H.; Chen, Z.; Li, X.; Tang, Y.; Li, X.; Zhang, S.; Ma, L.; Huang, X.
Source: Self-asserted source
Si zhang via Scopus - Elsevier

BIRC6 promotes hepatocellular carcinogenesis: Interaction of BIRC6 with p53 facilitating p53 degradation

International Journal of Cancer
2015 | Journal article
EID:

2-s2.0-84922211121

Contributors: Tang, W.; Xue, R.; Weng, S.; Wu, J.; Fang, Y.; Wang, Y.; Ji, L.; Hu, T.; Liu, T.; Huang, X. et al.
Source: Self-asserted source
Si zhang via Scopus - Elsevier

Caveolin-1 Confers Resistance of Hepatoma Cells to Anoikis by Activating IGF-1 Pathway

Cellular Physiology and Biochemistry
2015 | Journal article
EID:

2-s2.0-84953863445

Part of ISBN:

14219778 10158987

Contributors: Tang, W.; Feng, X.; Zhang, S.; Ren, Z.; Liu, Y.; Yang, B.; Lv, B.; Cai, Y.; Xia, J.; Ge, N.
Source: Self-asserted source
Si zhang via Scopus - Elsevier

Dl-3-n-butylphthalide inhibits platelet activation via inhibition of cPLA2-mediated TXA <inf>2</inf> synthesis and phosphodiesterase

Platelets
2015 | Journal article
EID:

2-s2.0-84942984352

Contributors: Ye, J.; Zhai, L.; Zhang, S.; Zhang, Y.; Chen, L.; Hu, L.; Zhang, S.; Ding, Z.
Source: Self-asserted source
Si zhang via Scopus - Elsevier

Overexpression of BIRC6 is a predictor of prognosis for colorectal cancer

PLoS ONE
2015 | Journal article
EID:

2-s2.0-84928819011

Contributors: Hu, T.; Weng, S.; Tang, W.; Xe, R.; Chen, S.; Cai, G.; Cai, Y.; Shen, X.; Zhang, S.; Dong, L.
Source: Self-asserted source
Si zhang via Scopus - Elsevier

Nucleotide-Binding Oligomerization Domain 2 Receptor Is Expressed in Platelets and Enhances Platelet Activation and Thrombosis

Circulation
2015-03-31 | Journal article
Part of ISSN: 0009-7322
Part of ISSN: 1524-4539
Source: Self-asserted source
Si zhang
grade
Preferred source (of 2)‎

Apollon modulates chemosensitivity in human esophageal squamous cell carcinoma

Oncotarget
2014 | Journal article
EID:

2-s2.0-84907072893

Contributors: Zhang, S.; Tang, W.; Weng, S.; Liu, X.; Rao, B.; Gu, J.; Chen, S.; Wang, Q.; Shen, X.; Xue, R. et al.
Source: Self-asserted source
Si zhang via Scopus - Elsevier

Bile acids override steatosis in farnesoid X receptor deficient mice in a model of non-alcoholic steatohepatitis

Biochemical and Biophysical Research Communications
2014 | Journal article
EID:

2-s2.0-84901243613

Contributors: Wu, W.; Liu, X.; Peng, X.; Xue, R.; Ji, L.; Shen, X.; Chen, S.; Gu, J.; Zhang, S.
Source: Self-asserted source
Si zhang via Scopus - Elsevier

Toll like receptor 2 knock-out attenuates carbon tetrachloride (CCl <inf>4</inf>)-induced liver fibrosis by downregulating MAPK and NF-κB signaling pathways

FEBS Letters
2014 | Journal article
EID:

2-s2.0-84901420610

Contributors: Ji, L.; Xue, R.; Tang, W.; Wu, W.; Hu, T.; Liu, X.; Peng, X.; Gu, J.; Chen, S.; Zhang, S.
Source: Self-asserted source
Si zhang via Scopus - Elsevier

Direct interaction between surface β1,4-galactosyltransferase 1 and epidermal growth factor receptor (EGFR) inhibits EGFR activation in hepatocellular carcinoma

Biochemical and Biophysical Research Communications
2013 | Journal article
EID:

2-s2.0-84880453138

Contributors: Tang, W.; Weng, S.; Zhang, S.; Wu, W.; Dong, L.; Shen, X.; Zhang, S.; Gu, J.; Xue, R.
Source: Self-asserted source
Si zhang via Scopus - Elsevier

P2Y<inf>12</inf> protects platelets from apoptosis via PI3k-dependent Bak/Bax inactivation

Journal of Thrombosis and Haemostasis
2013 | Journal article
EID:

2-s2.0-84873046406

Contributors: Zhang, S.; Ye, J.; Zhang, Y.; Xu, X.; Liu, J.; Zhang, S.H.; Kunapuli, S.P.; Ding, Z.
Source: Self-asserted source
Si zhang via Scopus - Elsevier

Tumor vascular disrupting agent 5,6-dimethylxanthenone-4-acetic acid inhibits platelet activation and thrombosis via inhibition of thromboxane A<inf>2</inf> signaling and phosphodiesterase

Journal of Thrombosis and Haemostasis
2013 | Journal article
EID:

2-s2.0-84885352873

Contributors: Zhang, S.H.; Zhang, Y.; Shen, J.; Zhang, S.; Chen, L.; Gu, J.; Mruk, J.S.; Cheng, G.; Zhu, L.; Kunapuli, S.P. et al.
Source: Self-asserted source
Si zhang via Scopus - Elsevier

BF066, a novel dual target antiplatelet agent without significant bleeding

PLoS ONE
2012 | Journal article
EID:

2-s2.0-84863994282

Contributors: Pan, C.; Wei, X.; Ye, J.; Liu, G.; Zhang, S.; Zhang, Y.; Du, H.; Ding, Z.
Source: Self-asserted source
Si zhang via Scopus - Elsevier

Increased platelet activation and thrombosis in transgenic mice expressing constitutively active P2Y<inf>12</inf>

Journal of Thrombosis and Haemostasis
2012 | Journal article
EID:

2-s2.0-84866857618

Contributors: Zhang, Y.; Ye, J.; Hu, L.; Zhang, S.; Zhang, S.H.; Li, Y.; Kunapuli, S.P.; Ding, Z.
Source: Self-asserted source
Si zhang via Scopus - Elsevier

Matrine Induces Apoptosis in Human Acute Myeloid Leukemia Cells via the Mitochondrial Pathway and Akt Inactivation

PLoS ONE
2012 | Journal article
EID:

2-s2.0-84867299726

Contributors: Zhang, S.; Zhang, Y.; Zhuang, Y.; Wang, J.; Ye, J.; Zhang, S.; Wu, J.; Yu, K.; Han, Y.
Source: Self-asserted source
Si zhang via Scopus - Elsevier

Methotrexate attenuates the Th17/IL-17 levels in peripheral blood mononuclear cells from healthy individuals and RA patients

Rheumatology International
2012 | Journal article
EID:

2-s2.0-84866249315

Contributors: Li, Y.; Jiang, L.; Zhang, S.; Yin, L.; Ma, L.; He, D.; Shen, J.
Source: Self-asserted source
Si zhang via Scopus - Elsevier

New approach to synthesize symmetrical and unsymmetrical 6-(N-Alkyl(Aryl)amino)-and 6-(N, N-dialkyl(Aryl)amino)-2,4-bis(Alkyl(Aryl)Thio) pyrimidines as anti-platelet agents

Phosphorus, Sulfur and Silicon and the Related Elements
2012 | Journal article
EID:

2-s2.0-84859208216

Contributors: Liu, G.; Xu, J.; Yu, M.; Chen, N.; Zhang, S.; Ding, Z.; Du, H.
Source: Self-asserted source
Si zhang via Scopus - Elsevier

Synthesis of N <sup>6</sup>-alkyl(aryl)-2-alkyl(aryl)thioadenosines as antiplatelet agents

European Journal of Medicinal Chemistry
2012 | Journal article
EID:

2-s2.0-84861599461

Contributors: Liu, G.; Xu, J.; Chen, N.; Zhang, S.; Ding, Z.; Du, H.
Source: Self-asserted source
Si zhang via Scopus - Elsevier

BF061, a novel antiplatelet and antithrombotic agent targeting P2Y <inf>12</inf> receptor and phosphodiesterase

Thrombosis and Haemostasis
2011 | Journal article
EID:

2-s2.0-82555193847

Contributors: Hu, L.; Fan, Z.; Du, H.; Ni, R.; Zhang, S.; Yin, K.; Ye, J.; Zhang, Y.; Wei, X.; Zhang, X. et al.
Source: Self-asserted source
Si zhang via Scopus - Elsevier

Novel synthesis approach and antiplatelet activity evaluation of 6-alkylamino-2,4-dialkyl(aryl)thiopyrimidines

Tetrahedron
2011 | Journal article
EID:

2-s2.0-79958772995

Contributors: Liu, G.; Xu, J.; Park, K.C.; Chen, N.; Zhang, S.; Ding, Z.; Wang, F.; Du, H.
Source: Self-asserted source
Si zhang via Scopus - Elsevier

BF0801, a novel adenine derivative, inhibits platelet activation via phosphodiesterase inhibition and P2Y <inf>12</inf> antagonism

Thrombosis and Haemostasis
2010 | Journal article
EID:

2-s2.0-79955859077

Contributors: Zhang, S.; Hu, L.; Du, H.; Guo, Y.; Zhang, Y.; Niu, H.; Jin, J.; Zhang, J.; Liu, J.; Zhang, X. et al.
Source: Self-asserted source
Si zhang via Scopus - Elsevier

Cdc34-mediated degradation of ATF5 is blocked by cisplatin

Journal of Biological Chemistry
2008 | Journal article
EID:

2-s2.0-49649097733

Contributors: Wei, Y.; Jiang, J.; Liu, D.; Zhou, J.; Chen, X.; Zhang, S.; Zong, H.; Yun, X.; Gu, J.
Source: Self-asserted source
Si zhang via Scopus - Elsevier

Investigation of volatile biomarkers in liver cancer blood using solid-phase microextraction and gas chromatography/mass spectrometry

Rapid Communications in Mass Spectrometry
2008 | Journal article
EID:

2-s2.0-42649087443

Contributors: Xue, R.; Dong, L.; Zhang, S.; Deng, C.; Liu, T.; Wang, J.; Shen, X.
Source: Self-asserted source
Si zhang via Scopus - Elsevier

Knockdown of BCL2L12 leads to cisplatin resistance in MDA-MB-231 breast cancer cells

Biochimica et Biophysica Acta - Molecular Basis of Disease
2008 | Journal article
EID:

2-s2.0-55049130997

Contributors: Hong, Y.; Yang, J.; Wu, W.; Wang, W.; Kong, X.; Wang, Y.; Yun, X.; Zong, H.; wei, Y.; Zhang, S. et al.
Source: Self-asserted source
Si zhang via Scopus - Elsevier
Items per page:
Page 1 of 2

Peer review (2 reviews for 2 publications/grants)

Review activity for Advanced science. (1)
Review activity for Journal of hematology & oncology. (1)