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Loop profile: 2069525

Keywords

sequence annotation, controlled vocabulary, ontology, microbial pathogenesis, synthetic DNA screening

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Works (15)

Annotation of Functions of Sequences of Concern and Its Relevance to the New Biosecurity Regulatory Framework in the United States

Applied Biosafety
2024-09-01 | Journal article
DOI: 10.1089/apb.2023.0030
Contributors: Gene D. Godbold; Matthew B. Scholz
Source: check_circle
Crossref

SeqScreen-Nano: a computational platform for streaming, in-field characterization of microbial pathogens

2023-09-03 | Conference paper
DOI: 10.1145/3584371.3612960
Contributors: Advait Balaji; Yunxi Liu; Michael G. Nute; Bingbing Hu; Anthony D. Kappell; Danielle S. Lesassier; Gene D. Godbold; Krista Ternus; Todd Treangen
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Crossref

Improved understanding of biorisk for research involving microbial modification using annotated sequences of concern.

Frontiers in bioengineering and biotechnology
2023-04-25 | Journal article
DOI: 10.3389/fbioe.2023.1124100
PMID: 37180048
PMC: PMC10167326
Contributors: Godbold GD; Hewitt FC; Kappell AD; Scholz MB; Agar SL; Treangen TJ; Ternus KL; Sandbrink JB; Koblentz GD
Source: Self-asserted source
Gene D. Godbold

SeqScreen-Nano: a computational platform for rapid, in-field characterization of previously unseen pathogens

2023-02-13 | Preprint
DOI: 10.1101/2023.02.10.528096
Contributors: Advait Balaji; Yunxi Liu; Michael G. Nute; Bingbing Hu; Anthony Kappell; Danielle S. LeSassier; Gene D. Godbold; Krista L. Ternus; Todd J. Treangen
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Crossref

Categorizing Sequences of Concern by Function To Better Assess Mechanisms of Microbial Pathogenesis

Infection and Immunity
2022 | Journal article
DOI: 10.1128/IAI.00334-21
WOSUID: WOS:000800095800017
Contributors: Godbold, Gene D.; Kappell, Anthony D.; LeSassier, Danielle S.; Treangen, Todd J.; Ternus, Krista L.
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SeqScreen: accurate and sensitive functional screening of pathogenic sequences via ensemble learning

Genome Biology
2022-12 | Journal article
DOI: 10.1186/s13059-022-02695-x
Contributors: Advait Balaji; Bryce Kille; Anthony D. Kappell; Gene D. Godbold; Madeline Diep; R. A. Leo Elworth; Zhiqin Qian; Dreycey Albin; Daniel J. Nasko; Nidhi Shah et al.
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Evaluating Metagenomic Analysis for Pathogen Transmission in Healthcare Settings

Infection Control & Hospital Epidemiology
2020 | Journal article
DOI: 10.1017/ICE.2020.768
WOSUID: WOS:000621851501002
Contributors: Hewitt, Curt; Weber, Katharina; LeSassier, Danielle; Kappell, Anthony; Schulte, Kathleen; Westfall, Nicole; Albright, Nicolette; Godbold, Gene; Palsikar, Veena; Acevedo, Carlos et al.
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Simulating transmission of ESKAPE pathogens plusC. difficilein relevant clinical scenarios

BMC Infectious Diseases
2020 | Journal article
DOI: 10.1186/S12879-020-05121-4
WOSUID: WOS:000542249800003
Contributors: Weber, Katharina L.; LeSassier, Danielle S.; Kappell, Anthony D.; Schulte, Kathleen Q.; Westfall, Nicole; Albright, Nicolette C.; Godbold, Gene D.; Palsikar, Veena; Acevedo, Carlos A.; Ternus, Krista L. et al.
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SeqScreen: a biocuration platform for robust taxonomic and biological process characterization of nucleic acid sequences of interest

IEEE International Conference on Bioinformatics and Biomedicine (BIBM)
2019 | Conference paper
DOI: 10.1109/BIBM47256.2019.8982987
WOSUID: WOS:000555804900316
Contributors: Albin, Dreycey; Nasko, Dan; Elworth, R. A. Leo; Lu, Jacob; Balaji, Advait; Diaz, Christian; Shah, Nidhi; Selengut, Jeremy; Hulme-Lowe, Chris; Muthu, Pravin et al.
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Biosynthesis and alternate targeting of the lysosomal cysteine protease cathepsin L

International Review of Cytology
2004 | Journal article
DOI: 10.1016/S0074-7696(04)41001-8
WOSUID: WOS:000226025800001
Contributors: Collette, J; Bocock, JP; Ahn, K; Chapman, RL; Godbold, G; Yeyeodu, S; Erickson, AH
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A Rho-like small GTPase of Entamoeba histolytica contains an unusual amino acid residue in a conserved GDP-stabilization region and is not a substrate for C3 exoenzyme

Experimental Parasitology
2002 | Journal article
DOI: 10.1016/S0014-4894(02)00101-7
WOSUID: WOS:000179436600004
Contributors: Godbold, GD; Corbett, KD; Mann, BJ
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Cell killing by the human parasite Entamoeba histolytica is inhibited by the Rho-inactivating C3 exoenzyme

Molecular and Biochemical Parasitology
2000 | Journal article
DOI: 10.1016/S0166-6851(00)00207-3
WOSUID: WOS:000087166900016
Contributors: Godbold, GD; Mann, BJ
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Biosynthesis and intracellular targeting of the lysosomal aspartic proteinase cathepsin D

Advances in Experimental Medicine and Biology
1998 | Journal article
DOI: 10.1007/978-1-4615-5373-1_21
WOSUID: WOS:000073382400021
Contributors: Godbold, GD; Ahn, K; Yeyeodu, S; Lee, LF; Ting, JPY; Erickson, AH
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Involvement of the actin cytoskeleton and p21(rho)-family GTPases in the pathogenesis of the human protozoan parasite Entamoeba histolytica

Brazilian Journal of Medical and Biological Research
1998 | Journal article
DOI: 10.1590/S0100-879X1998000800004
WOSUID: WOS:000075442400004
Contributors: Godbold, GD; Mann, BJ
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THE PH-DEPENDENT MEMBRANE ASSOCIATION OF PROCATHEPSIN-L IS MEDIATED BY A 9-RESIDUE SEQUENCE WITHIN THE PROPEPTIDE

Journal of Biological Chemistry
1994 | Journal article
WOSUID: WOS:A1994MR21900090
Contributors: MCINTYRE, GF; GODBOLD, GD; ERICKSON, AH
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Peer review (1 review for 1 publication/grant)

Review activity for Health security. (1)
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