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Employment (3)

Bit Bio: Cambridge, GB

2021-02-27 to present | Senior Scientist, Computational Biology
Employment
Source: Self-asserted source
Joel Chappell

KU Leuven: Leuven, BE

2018-09-26 to 2020-12-31 | Post-doctoral researcher (Stem Cell Institute)
Employment
Source: Self-asserted source
Joel Chappell

University College London: London, London, GB

2013-09-01 to 2014-08-31 | Research Assistant (Institute of Child Health )
Employment
Source: Self-asserted source
Joel Chappell

Education and qualifications (3)

University of Cambridge: Cambridge, Cambridgeshire, GB

2014-10-01 to 2018-06-01 | PhD (Medicine )
Education
Source: Self-asserted source
Joel Chappell

Imperial College London: London, London, GB

2012-09-01 to 2013-08-31 | Master - Human Molecular Genetics
Education
Source: Self-asserted source
Joel Chappell

Loughborough University: Loughborough, Leicestershire, GB

2009-09-01 to 2012-06-18 | BSc - Human Biology
Education
Source: Self-asserted source
Joel Chappell

Professional activities (1)

International Society for Stem Cell Research: Skokie, IL, US

2018-04-01 to present
Membership
Source: Self-asserted source
Joel Chappell

Works (17)

Inferring regulators of cell identity in the human adult pancreas

NAR Genomics and Bioinformatics
2023-07-05 | Journal article
Contributors: Lotte Vanheer; Federica Fantuzzi; San Kit To; Andrea Schiavo; Matthias Van Haele; Tessa Ostyn; Tine Haesen; Xiaoyan Yi; Adrian Janiszewski; Joel Chappell et al.
Source: check_circle
Crossref

Cellular mechanisms of oligoclonal vascular smooth muscle cell expansion in cardiovascular disease

Cardiovascular Research
2023-05-22 | Journal article
Contributors: Matt D Worssam; Jordi Lambert; Sebnem Oc; James C K Taylor; Annabel L Taylor; Lina Dobnikar; Joel Chappell; Jennifer L Harman; Nichola L Figg; Alison Finigan et al.
Source: check_circle
Crossref

A multi-omics genome-and-transcriptome single-cell atlas of human preimplantation embryogenesis reveals the cellular and molecular impact of chromosome instability

2023-03-10 | Preprint
Contributors: Elia Fernandez Gallardo; Alejandro Sifrim; Joel Chappell; Jonas Demeulemeester; Jennifer Clara Herrmann; Robin Vermotte; Alison Kerremans; Michiel Van der Haegen; Jens Van Herck; Sebastiaan Vanuytven et al.
Source: check_circle
Crossref

Organoids from human tooth showing epithelial stemness phenotype and differentiation potential

Cellular and Molecular Life Sciences
2022-03 | Journal article
Contributors: Lara Hemeryck; Florian Hermans; Joel Chappell; Hiroto Kobayashi; Diether Lambrechts; Ivo Lambrichts; Annelies Bronckaers; Hugo Vankelecom
Source: check_circle
Crossref

Interleukin-6 is an activator of pituitary stem cells upon local damage, a competence quenched in the aging gland

Proceedings of the National Academy of Sciences
2021-06-22 | Journal article
Contributors: Annelies Vennekens; Emma Laporte; Florian Hermans; Benoit Cox; Elodie Modave; Adrian Janiszewski; Charlotte Nys; Hiroto Kobayashi; Bert Malengier-Devlies; Joel Chappell et al.
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Crossref

Telomere damage promotes vascular smooth muscle cell senescence and immune cell recruitment after vessel injury

Communications Biology
2021-05-21 | Journal article
Contributors: Anna K. Uryga; Mandy O. J. Grootaert; Abel M. Garrido; Sebnem Oc; Kirsty Foote; Joel Chappell; Alison Finigan; Francesca Rossiello; Fabrizio d’Adda di Fagagna; Dimitra Aravani et al.
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Crossref

Primed smooth muscle cells acting as first responder cells in disease

2020-10-19 | Preprint
Contributors: Matt D Worssam; Jordi Lambert; Sebnem Oc; Annabel L Taylor; Lina Dobnikar; Joel Chappell; Jennifer L Harman; Nichola L Figg; Alison Finigan; Kirsty Foote et al.
Source: check_circle
Crossref

Predicting the Key Regulators of Cell Identity in Human Adult Pancreas

2020-09-25 | Preprint
Contributors: Lotte Vanheer; Federica Fantuzzi; San Kit To; Andrea Alex Schiavo; Matthias Van Haele; Tine Haesen; Xiaoyan Yi; Adrian Janiszewski; Joel Chappell; Adrien Rihoux et al.
Source: check_circle
Crossref

Tox4 modulates cell fate reprogramming

Journal of Cell Science
2019-10-15 | Journal article
Contributors: Lotte Vanheer; Juan Song; Natalie De Geest; Adrian Janiszewski; Irene Talon; Caterina Provenzano; Taeho Oh; Joel Chappell; Vincent Pasque
Source: check_circle
Crossref

Dynamic reversal of random X-Chromosome inactivation during iPSC reprogramming

Genome Research
2019-09-12 | Journal article
Part of ISSN: 1088-9051
Part of ISSN: 1549-5469
Source: Self-asserted source
Joel Chappell

Recent Advances in Understanding the Reversal of Gene Silencing During X Chromosome Reactivation

Frontiers in Cell and Developmental Biology
2019-09-03 | Journal article
Part of ISSN: 2296-634X
Source: Self-asserted source
Joel Chappell

Epigenetic Regulation of Vascular Smooth Muscle Cells by Histone H3 Lysine 9 Dimethylation Attenuates Target Gene-Induction by Inflammatory Signaling

Arteriosclerosis, Thrombosis, and Vascular Biology
2019-08-22 | Journal article
Part of ISSN: 1079-5642
Part of ISSN: 1524-4636
Source: Self-asserted source
Joel Chappell

Vascular Smooth Muscle Cell Plasticity and Autophagy in Dissecting Aortic Aneurysms

Arteriosclerosis, Thrombosis, and Vascular Biology
2019-06 | Journal article
Part of ISSN: 1079-5642
Part of ISSN: 1524-4636
Source: Self-asserted source
Joel Chappell

Disease-relevant transcriptional signatures identified in individual smooth muscle cells from healthy mouse vessels

Nature Communications
2018-12 | Journal article
Part of ISSN: 2041-1723
Source: Self-asserted source
Joel Chappell

Vascular smooth muscle cell heterogeneity and plasticity in models of cardiovascular disease

Apollo - University of Cambridge Repository
2018-04-03 | Dissertation or Thesis
Source: Self-asserted source
Joel Chappell

Extensive Proliferation of a Subset of Differentiated, yet Plastic, Medial Vascular Smooth Muscle Cells Contributes to Neointimal Formation in Mouse Injury and Atherosclerosis Models.

Circulation Research
2016-12-09 | Journal article
Source: Self-asserted source
Joel Chappell

The CXCL12/CXCR4 Axis Plays a Critical Role in Coronary Artery Development.

Developmental Cell
2015-05-26 | Journal article
Source: Self-asserted source
Joel Chappell