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Works (32)

Insights into phenotypic and functional CD8+ TRM heterogeneity

Immunological Reviews
2023-07 | Journal article
DOI: 10.1111/imr.13218
Contributors: Maximilian Heeg; Ananda W. Goldrath
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Crossref

License to kill: Retinoic acid programs T cells for tissue residency

Journal of Experimental Medicine
2023-05-01 | Journal article
DOI: 10.1084/jem.20230161
Contributors: Maximilian Heeg; Ananda W. Goldrath
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Crossref

Mixed Lineage Leukemia (Mll1) establishes global histone H3K4 trimethylation and stem like memory Cd8 T cell formation

2023-01-20 | Preprint
DOI: 10.1101/2023.01.18.524461
Contributors: Adam J. Getzler; Megan A. Frederick; Huitian Diao; Justin J. Milner; Simon Bélanger; Shanel M. Tsuda; Dominic Albao; Jihye Kim; Shane Crotty; Ananda Goldrath et al.
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Crossref

Tissue-resident memory CD8+ T cells possess unique transcriptional, epigenetic and functional adaptations to different tissue environments

Nature Immunology
2022-07 | Journal article
DOI: 10.1038/s41590-022-01229-8
Contributors: John T. Crowl; Maximilian Heeg; Amir Ferry; J. Justin Milner; Kyla D. Omilusik; Clara Toma; Zhaoren He; John T. Chang; Ananda W. Goldrath
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Crossref

CD8+ T cell metabolism in infection and cancer

Nature Reviews Immunology
2021-11 | Journal article
DOI: 10.1038/s41577-021-00537-8
Contributors: Miguel Reina-Campos; Nicole E. Scharping; Ananda W. Goldrath
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Crossref

Ubiquitin Specific Protease 1 Expression and Function in T Cell Immunity

The Journal of Immunology
2021-09-01 | Journal article
DOI: 10.4049/jimmunol.2100303
Contributors: Kyla D Omilusik; Marija S Nadjsombati; Tomomi M Yoshida; Laura A Shaw; John Goulding; Ananda W Goldrath
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Crossref

Bromodomain protein BRD4 directs and sustains CD8 T cell differentiation during infection

Journal of Experimental Medicine
2021-05 | Journal article
DOI: 10.1084/jem.20202512
Part of ISSN: 0022-1007
Contributors: J. Justin Milner; Clara Toma; Sara Quon; Kyla Omilusik; Nicole E. Scharping; Anup Dey; Miguel Reina-Campos; Hongtuyet Nguyen; Adam J. Getzler; Huitian Diao et al.
Source: Self-asserted source
Ananda Goldrath via Crossref Metadata Search

Hypoxia-inducible factor activity promotes antitumor effector function and tissue residency by CD8+ T cells

Journal of Clinical Investigation
2021-04-01 | Journal article
DOI: 10.1172/jci143729
Part of ISSN: 0021-9738
Contributors: Ilkka Liikanen; Colette Lauhan; Sara Quon; Kyla Omilusik; Anthony T. Phan; Laura Barceló Bartrolí; Amir Ferry; John Goulding; Joyce Chen; James P. Scott-Browne et al.
Source: Self-asserted source
Ananda Goldrath via Crossref Metadata Search

Delineation of a molecularly distinct terminally differentiated memory CD8 T cell population

Proceedings of the National Academy of Sciences
2020-09 | Journal article
DOI: 10.1073/pnas.2008571117
Part of ISSN: 0027-8424
Contributors: J. Justin Milner; Hongtuyet Nguyen; Kyla Omilusik; Miguel Reina-Campos; Matthew Tsai; Clara Toma; Arnaud Delpoux; Brigid S. Boland; Stephen M. Hedrick; John T. Chang et al.
Source: Self-asserted source
Ananda Goldrath via Crossref Metadata Search

Heterogeneity and clonal relationships of adaptive immune cells in ulcerative colitis revealed by single-cell analyses

Science Immunology
2020-08 | Journal article
DOI: 10.1126/sciimmunol.abb4432
Part of ISSN: 2470-9468
Contributors: Brigid S. Boland; Zhaoren He; Matthew S. Tsai; Jocelyn G. Olvera; Kyla D. Omilusik; Han G. Duong; Eleanor S. Kim; Abigail E. Limary; Wenhao Jin; J. Justin Milner et al.
Source: Self-asserted source
Ananda Goldrath via Crossref Metadata Search

Early precursors and molecular determinants of tissue-resident memory CD8 + T lymphocytes revealed by single-cell RNA sequencing

Science Immunology
2020-05 | Journal article
DOI: 10.1126/sciimmunol.aaz6894
Part of ISSN: 2470-9468
Contributors: Nadia S. Kurd; Zhaoren He; Tiani L. Louis; J. Justin Milner; Kyla D. Omilusik; Wenhao Jin; Matthew S. Tsai; Christella E. Widjaja; Jad N. Kanbar; Jocelyn G. Olvera et al.
Source: Self-asserted source
Ananda Goldrath via Crossref Metadata Search

Heterogenous Populations of Tissue-Resident CD8+ T Cells Are Generated in Response to Infection and Malignancy

Immunity
2020-05 | Journal article
DOI: 10.1016/j.immuni.2020.04.007
Part of ISSN: 1074-7613
Contributors: J. Justin Milner; Clara Toma; Zhaoren He; Nadia S. Kurd; Quynh P. Nguyen; Bryan McDonald; Lauren Quezada; Christella E. Widjaja; Deborah A. Witherden; John T. Crowl et al.
Source: Self-asserted source
Ananda Goldrath via Crossref Metadata Search

Remembering to remember: T cell memory maintenance and plasticity

Current Opinion in Immunology
2019-06 | Journal article
DOI: 10.1016/j.coi.2019.04.009
Part of ISSN: 0952-7915
Contributors: Kyla D Omilusik; Ananda W Goldrath
Source: Self-asserted source
Ananda Goldrath via Crossref Metadata Search

Origins of CD4+ circulating and tissue‐resident memory T‐cells

Immunology
2019-05 | Journal article
DOI: 10.1111/imm.13059
Contributors: Quynh P. Nguyen; Tianda Z. Deng; Deborah A. Witherden; Ananda W. Goldrath
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Crossref

Transcriptional Control of Memory T Cell Differentiation

Blood
2018-11 | Journal article
DOI: 10.1182/blood-2018-99-109536
Part of ISSN: 0006-4971
Contributors: Ananda Goldrath
Source: Self-asserted source
Ananda Goldrath via Crossref Metadata Search

The Transcription Factor Runx3 Establishes Chromatin Accessibility of cis-Regulatory Landscapes that Drive Memory Cytotoxic T Lymphocyte Formation

Immunity
2018-04 | Journal article
DOI: 10.1016/j.immuni.2018.03.028
Part of ISSN: 1074-7613
Contributors: Dapeng Wang; Huitian Diao; Adam J. Getzler; Walter Rogal; Megan A. Frederick; Justin Milner; Bingfei Yu; Shane Crotty; Ananda W. Goldrath; Matthew E. Pipkin
Source: Self-asserted source
Ananda Goldrath via Crossref Metadata Search

Transcriptional programming of tissue-resident memory CD8+ T cells

Current Opinion in Immunology
2018-04 | Journal article
DOI: 10.1016/j.coi.2018.03.017
Part of ISSN: 0952-7915
Contributors: J Justin Milner; Ananda W Goldrath
Source: Self-asserted source
Ananda Goldrath via Crossref Metadata Search

Sustained Id2 regulation of E proteins is required for terminal differentiation of effector CD8+ T cells

Journal of Experimental Medicine
2018-03-05 | Journal article
DOI: 10.1084/jem.20171584
Contributors: Kyla D. Omilusik; Marija S. Nadjsombati; Laura A. Shaw; Bingfei Yu; J. Justin Milner; Ananda W. Goldrath
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Crossref
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Runx3 programs CD8+ T cell residency in non-lymphoid tissues and tumours

Nature
2017 | Journal article
DOI: 10.1038/nature24993
Part of ISSN: 0028-0836
Contributors: J. Justin Milner; Clara Toma; Bingfei Yu; Kai Zhang; Kyla Omilusik; Anthony T. Phan; Dapeng Wang; Adam J. Getzler; Toan Nguyen; Shane Crotty et al.
Source: Self-asserted source
Ananda Goldrath via Crossref Metadata Search

An HIF-1α/VEGF-A Axis in Cytotoxic T Cells Regulates Tumor Progression

Cancer Cell
2017-11 | Journal article
DOI: 10.1016/j.ccell.2017.10.003
Part of ISSN: 1535-6108
Contributors: Asis Palazon; Petros A. Tyrakis; David Macias; Pedro Veliça; Helene Rundqvist; Susan Fitzpatrick; Nikola Vojnovic; Anthony T. Phan; Niklas Loman; Ingrid Hedenfalk et al.
Source: Self-asserted source
Ananda Goldrath via Crossref Metadata Search

Metabolic and Epigenetic Coordination of T Cell and Macrophage Immunity

Immunity
2017-05 | Journal article
DOI: 10.1016/j.immuni.2017.04.016
Part of ISSN: 1074-7613
Contributors: Anthony T. Phan; Ananda W. Goldrath; Christopher K. Glass
Source: Self-asserted source
Ananda Goldrath via Crossref Metadata Search

Epigenetic landscapes reveal transcription factors that regulate CD8+ T cell differentiation

Nature Immunology
2017-03 | Journal article
DOI: 10.1038/ni.3706
Part of ISSN: 1529-2908
Contributors: Bingfei Yu; Kai Zhang; J Justin Milner; Clara Toma; Runqiang Chen; James P Scott-Browne; Renata M Pereira; Shane Crotty; John T Chang; Matthew E Pipkin et al.
Source: Self-asserted source
Ananda Goldrath via Crossref Metadata Search

Early transcriptional and epigenetic regulation of CD8+ T cell differentiation revealed by single-cell RNA sequencing

Nature Immunology
2017-02 | Journal article
DOI: 10.1038/ni.3688
Part of ISSN: 1529-2908
Contributors: Boyko Kakaradov; Janilyn Arsenio; Christella E Widjaja; Zhaoren He; Stefan Aigner; Patrick J Metz; Bingfei Yu; Ellen J Wehrens; Justine Lopez; Stephanie H Kim et al.
Source: Self-asserted source
Ananda Goldrath via Crossref Metadata Search

Constitutive Glycolytic Metabolism Supports CD8+ T Cell Effector Memory Differentiation during Viral Infection

Immunity
2016-11 | Journal article
DOI: 10.1016/j.immuni.2016.10.017
Part of ISSN: 1074-7613
Contributors: Anthony T. Phan; Andrew L. Doedens; Asis Palazon; Petros A. Tyrakis; Kitty P. Cheung; Randall S. Johnson; Ananda W. Goldrath
Source: Self-asserted source
Ananda Goldrath via Crossref Metadata Search

S-2-hydroxyglutarate regulates CD8+ T-lymphocyte fate

Nature
2016-10 | Journal article
DOI: 10.1038/nature20165
Part of ISSN: 0028-0836
Contributors: Petros A. Tyrakis; Asis Palazon; David Macias; Kian. L. Lee; Anthony. T. Phan; Pedro Veliça; Jia You; Grace S. Chia; Jingwei Sim; Andrew Doedens et al.
Source: Self-asserted source
Ananda Goldrath via Crossref Metadata Search

Oxygen Sensing by T Cells Establishes an Immunologically Tolerant Metastatic Niche

Cell
2016-08 | Journal article
DOI: 10.1016/j.cell.2016.07.032
Part of ISSN: 0092-8674
Contributors: David Clever; Rahul Roychoudhuri; Michael G. Constantinides; Michael H. Askenase; Madhusudhanan Sukumar; Christopher A. Klebanoff; Robert L. Eil; Heather D. Hickman; Zhiya Yu; Jenny H. Pan et al.
Source: Self-asserted source
Ananda Goldrath via Crossref Metadata Search

Molecular Programming of Tumor-Infiltrating CD8+ T Cells and IL15 Resistance

Cancer Immunology Research
2016-08-02 | Journal article
DOI: 10.1158/2326-6066.cir-15-0178
Part of ISSN: 2326-6066
Contributors: Andrew L. Doedens; Mark P. Rubinstein; Emilie T. Gross; J. Adam Best; David H. Craig; Megan K. Baker; David J. Cole; Jack D. Bui; Ananda W. Goldrath
Source: Self-asserted source
Ananda Goldrath via Crossref Metadata Search

Hypoxia-inducible factors regulate T cell metabolism and function

Molecular Immunology
2015 | Journal article
DOI: 10.1016/j.molimm.2015.08.004
Part of ISSN: 0161-5890
Contributors: Anthony T. Phan; Ananda W. Goldrath
Source: Self-asserted source
Ananda Goldrath via Crossref Metadata Search

Transcriptional repressor ZEB2 promotes terminal differentiation of CD8+ effector and memory T cell populations during infection

Journal of Experimental Medicine
2015-10 | Journal article
DOI: 10.1084/jem.20150194
Part of ISSN: 0022-1007
Contributors: Kyla D. Omilusik; J. Adam Best; Bingfei Yu; Steven Goossens; Alexander Weidemann; Jessica V. Nguyen; Eve Seuntjens; Agata Stryjewska; Christiane Zweier; Rahul Roychoudhuri et al.
Source: Self-asserted source
Ananda Goldrath via Crossref Metadata Search

Central Tolerance Matters

Immunity
2005-08 | Journal article
DOI: 10.1016/j.immuni.2005.08.004
Part of ISSN: 1074-7613
Contributors: Ananda W. Goldrath; Stephen M. Hedrick
Source: Self-asserted source
Ananda Goldrath via Crossref Metadata Search

Delineation of a molecularly distinct terminally differentiated memory CD8 T cell population

Other
DOI: 10.1101/2020.07.17.207266
Contributors: J. Justin Milner; Hongtuyet Nguyen; Kyla Omilusik; Miguel Reina-Campos; Matthew Tsai; Clara Toma; Arnaud D. Delpoux; Brigid S. Boland; Stephen M. Hedrick; John T. Chang et al.
Source: Self-asserted source
Ananda Goldrath via Crossref Metadata Search

Functional delineation of tissue-resident CD8+ T cell heterogeneity during infection and cancer

Other
DOI: 10.1101/2020.03.05.979146
Contributors: J. Justin Milner; Clara Toma; Zhaoren He; Nadia S. Kurd; Quynh P. Nguyen; Bryan McDonald; Lauren Quezada; Christella E. Widjaja; Deborah A. Witherden; John T. Crowl et al.
Source: Self-asserted source
Ananda Goldrath via Crossref Metadata Search
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