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University of Helsinki: Helsinki, FI

2019-08-01 to present | MD, PhD student (Lab Kekalainen, Translational Immunology Research Program)
Employment
Source: Self-asserted source
Joona Sarkkinen

Works (13)

Altered immune landscape of cervical lymph nodes reveals Epstein-Barr virus signature in multiple sclerosis

Science Immunology
2025-02-28 | Journal article
DOI: 10.1126/sciimmunol.adl3604
Contributors: Joona Sarkkinen; Dawit A. Yohannes; Nea Kreivi; Pia Dürnsteiner; Alexandra Elsakova; Jani Huuhtanen; Kirsten Nowlan; Goran Kurdo; Riikka Linden; Mika Saarela et al.
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Crossref

Reduction in mucosal-associated invariant T cells (MAIT) in APECED patients is associated with elevated serum IFN-γ concentration

European Journal of Immunology
2024-12 | Journal article | Author
DOI: 10.1002/eji.202451189
SOURCE-WORK-ID:

8aca14a6-44e0-4df2-acf6-b8bd341c0101

WOSUID:

001315175500001

PMID: 39292205
EID:

2-s2.0-85204487995
Contributors: Iivo Hetemäki; Joona Sarkkinen; Huai Hui Wong; Nelli Heikkilä; Saila Laakso; Simo Santeri Miettinen; Mikko Mäyränpää; Outi Mäkitie; Petteri Arstila; Eliisa Laura Johanna Kekäläinen
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University of Helsinki

Parvovirus B19 and Human Herpes Virus 6B and 7 Are Frequently Found DNA Viruses in the Human Thymus But Show No Definitive Link With Myasthenia Gravis

The Journal of Infectious Diseases
2024-12-05 | Journal article
DOI: 10.1093/infdis/jiae600
Contributors: Kirsten Nowlan; Leo Hannolainen; Irini M Assimakopoulou; Pia Dürnsteiner; Joona Sarkkinen; Santeri Suokas; Lea Hedman; Pentti J Tienari; Klaus Hedman; Mikael Niku et al.
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Crossref
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HHV-6B, HHV-7, and B19V Are Frequently Found DNA Viruses in the Human Thymus but Show No Definitive Link with Myasthenia Gravis

2024-07-03 | Preprint
DOI: 10.1101/2024.06.27.600940
Contributors: Kirsten Nowlan; Leo Hannolainen; Irini M Assimakopoulou; Pia Dürnsteiner; Joona Sarkkinen; Santeri Suokas; Lea Hedman; Pentti J. Tienari; Klaus Hedman; Mikael Niku et al.
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Crossref

Dysregulated germinal centre reaction with expanded T follicular helper cells in APECED lymph nodes

Journal of Allergy and Clinical Immunology
2023-12-19 | Journal article | Author
DOI: 10.1016/j.jaci.2023.12.004
SOURCE-WORK-ID:

b4ba87c9-6dcd-4803-b468-de56717f7e55

WOSUID:

001239476200001

EID:

2-s2.0-85182360607
Contributors: Iivo Hetemäki; Joona Sarkkinen; Nelli Heikkilä; Karen Drechsel; Mikko Mäyränpää; Anniina Färkkilä; Saila Laakso; Outi Mäkitie; Petteri Arstila; Eliisa Laura Johanna Kekäläinen
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University of Helsinki

Deep cervical lymph nodes of patients with multiple sclerosis show dysregulated B cells in the presence of Epstein-Barr virus

2023-10-23 | Preprint
DOI: 10.1101/2023.10.22.23297386
Contributors: Joona Sarkkinen; Dawit Yohannes; Nea Kreivi; Pia Dürnsteiner; Jani Huuhtanen; Kirsten Nowlan; Goran Kurdo; Riikka Linden; Mika Saarela; Pentti J Tienari et al.
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Crossref

A skewed ratio of free light chains is more common in patients with late-onset than early-onset myasthenia gravis

Immunology Letters
2023-08 | Journal article | Author
DOI: 10.1016/j.imlet.2023.07.001
SOURCE-WORK-ID:

e5cff136-1b8b-472c-b4b6-c8811131ec3f

WOSUID:

001040115200001

PMID: 37414259
EID:

2-s2.0-85164372742
Contributors: Chris Myllynen; Joona Sarkkinen; Sari Atula; Pentti Tienari; Eliisa Laura Johanna Kekäläinen; Sini Laakso
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University of Helsinki

Single-cell spatial atlas of tertiary lymphoid structures in ovarian cancer

2023-05-18 | Preprint
DOI: 10.1101/2023.05.16.540946
Contributors: Joona Sarkkinen; Ada Junquera; Ella Anttila; Angela Szabo; Fernando Perez; Inga-Maria Launonen; Anna Laury; Julia Casado; Eliisa Kekäläinen; Anniina Färkkilä
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Crossref

Uusi IKZF2-geenin mutaatiosta johtuva immuunipuutos

Duodecim
2022 | Journal article | Author
SOURCE-WORK-ID:

183e36ca-65e0-47de-84af-74f86de6ddf3
Contributors: Iivo Hetemäki; Meri Kaustio; Matias Kinnunen; Nelli Heikkilä; Salla Keskitalo; Kirsten Nowlan; Simo Santeri Miettinen; Joona Sarkkinen; Virpi Glumoff; Noora Andersson et al.
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University of Helsinki

Ectopic germinal centers in the thymus accurately predict prognosis of myasthenia gravis after thymectomy

Modern Pathology
2022-09 | Journal article
DOI: 10.1038/s41379-022-01070-2
Contributors: Joona Sarkkinen; Johannes Dunkel; Anni Tuulasvaara; Antti Huuskonen; Sari Atula; Eliisa Kekäläinen; Sini M. Laakso
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Crossref
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Loss-of-function mutation in IKZF2 leads to immunodeficiency with dysregulated germinal center reactions and reduction of MAIT cells

Science Immunology
2021-11-26 | Journal article
DOI: 10.1126/sciimmunol.abe3454
Contributors: Iivo Hetemäki; Meri Kaustio; Matias Kinnunen; Nelli Heikkilä; Salla Keskitalo; Kirsten Nowlan; Simo Miettinen; Joona Sarkkinen; Virpi Glumoff; Noora Andersson et al.
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Anti‐cytokine autoantibodies are rare in chronic graft‐versus‐host disease

Scandinavian Journal of Immunology
2021-09 | Journal article
DOI: 10.1111/sji.13091
Contributors: Joona Sarkkinen; Sofie Lundgren; Maija Itälä‐Remes; Urpu Salmenniemi; Satu Mustjoki; Pärt Peterson; Eliisa Kekäläinen
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Crossref
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Loss-of-function mutation in IKZF2 leads to immunodeficiency with dysregulated germinal center reactions and reduction of MAIT cells

2021-08-28 | Other
DOI: 10.1101/2021.08.25.21262015
Contributors: Iivo Hetemäki; Meri Kaustio; Matias Kinnunen; Nelli Heikkilä; Salla Keskitalo; Simo Miettinen; Joona Sarkkinen; Virpi Glumoff; Noora Andersson; Kaisa Kettunen et al.
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Crossref

Peer review (1 review for 1 publication/grant)

Review activity for Orphanet journal of rare diseases. (1)
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