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Lysosomes in the immunometabolic reprogramming of immune cells in atherosclerosis

Nature Reviews Cardiology
2025-03 | Journal article
DOI: 10.1038/s41569-024-01072-4
Contributors: Fabrizia Bonacina; Xiangyu Zhang; Nicolas Manel; Laurent Yvan-Charvet; Babak Razani; Giuseppe D. Norata
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Author Correction: Metabolic reprogramming of naïve regulatory T cells by IL-7 and IL-15 promotes their persistence and performance upon adoptive transfer

Communications Biology
2025-02-23 | Journal article
DOI: 10.1038/s42003-025-07637-4
Contributors: Jessica Filoni; Arianna Ferrari; Tatiana Jofra; Anna Rita Putignano; Lorenzo Da Dalt; Susanna Cesarano; Carla Di Dedda; Fabrizia Bonacina; Federica Marchesi; Giuseppe Danilo Norata et al.
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Metabolic reprogramming of naïve regulatory T cells by IL-7 and IL-15 promotes their persistence and performance upon adoptive transfer

Communications Biology
2025-01-21 | Journal article
DOI: 10.1038/s42003-024-07381-1
Contributors: Jessica Filoni; Arianna Ferrari; Tatiana Jofra; Anna Rita Putignano; Lorenzo Da Dalt; Susanna Cesarano; Carla Di Dedda; Fabrizia Bonacina; Federica Marchesi; Giuseppe Danilo Norata et al.
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ORION-8: one step closer to understanding the safety and efficacy of inclisiran

Cardiovascular Research
2024-10-14 | Journal article
DOI: 10.1093/cvr/cvae166
Contributors: Lale Tokgözoğlu; Giuseppe Danilo Norata
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Understanding immunometabolism in cardiovascular disease: translating research into practice

European Heart Journal
2024-07-09 | Journal article
DOI: 10.1093/eurheartj/ehae131
Contributors: Giuseppe Danilo Norata; David Sancho; Jan Van den Bossche; Daniel F J Ketelhuth
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Effects of low-dose monacolin K on the circulating proteome in individuals with suboptimal cholesterolaemia: A randomised clinical trial

2024-06-21 | Preprint
DOI: 10.1101/2024.06.19.24309106
Contributors: Arrigo F.G. Cicero; Patrizia Uboldi; Giangiacomo Beretta; Federica Fogacci; Elisa Grandi; Monika Svecla; Giuseppe Danilo Norata
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Long-Term Follow-Up of Custom-Made Porous Hydroxyapatite Cranioplasties: Analysis of Infections in Adult and Pediatric Patients

Journal of Clinical Medicine
2024-02-17 | Journal article
DOI: 10.3390/jcm13041133
Contributors: Francesca Carolina Mannella; Francesca Faedo; Marta Fumagalli; Giuseppe Danilo Norata; Ismail Zaed; Franco Servadei
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The Impact of Red Yeast Rice Extract Use on the Occurrence of Muscle Symptoms and Liver Dysfunction: An Update from the Adverse Event Reporting Systems and Available Meta-Analyses

Nutrients
2024-02-02 | Journal article
DOI: 10.3390/nu16030444
Contributors: Giuseppe Danilo Norata; Maciej Banach
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Oral strategies to target proprotein convertase subtilisin/kexin type 9 and lipoprotein(a): the new frontier of lipid lowering

European Heart Journal
2023-12-21 | Journal article
DOI: 10.1093/eurheartj/ehad682
Contributors: Giuseppe Danilo Norata; Lale Tokgözoğlu
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Gonadal sex vs genetic sex in experimental atherosclerosis

Atherosclerosis
2023-11 | Journal article
DOI: 10.1016/j.atherosclerosis.2023.117277
Contributors: Jasmine Nour; Fabrizia Bonacina; Giuseppe D. Norata
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Rhabdomyolysis or Severe Acute Hepatitis Associated with the Use of Red Yeast Rice Extracts: an Update from the Adverse Event Reporting Systems

Current Atherosclerosis Reports
2023-11 | Journal article
DOI: 10.1007/s11883-023-01157-4
Contributors: Maciej Banach; Giuseppe Danilo Norata
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Dendritic cell immunoreceptor 2 (DCIR2) deficiency decreases hepatic conventional dendritic cell content but not the progression of diet‐induced obesity

Immunity, Inflammation and Disease
2023-10 | Journal article
DOI: 10.1002/iid3.1024
Contributors: Rossella Bellini; Annalisa Moregola; Jasmine Nour; Patrizia Uboldi; Fabrizia Bonacina; Giuseppe D. Norata
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The inhibition of inner mitochondrial fusion in hepatocytes reduces NAFL and improves metabolic profile during obesity by modulating bile acid conjugation

2023-10-27 | Other
DOI: 10.1093/cvr/cvad169
Contributors: Giuseppe Danilo Norata; Luca Scorrano; Nico Mitro; Diletta Dolfini
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Cardiac lipid metabolism, mitochondrial function, and heart failure

Cardiovascular Research
2023-08-19 | Journal article
DOI: 10.1093/cvr/cvad100
Contributors: Lorenzo Da Dalt; Ainara G Cabodevilla; Ira J Goldberg; Giuseppe Danilo Norata
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Fibronectin extra domain a limits liver dysfunction and protects mice during acute inflammation

Atherosclerosis Plus
2023-06 | Journal article
DOI: 10.1016/j.athplu.2023.05.002
Contributors: Vivek Krishna Pulakazhi Venu; Annalisa Moregola; Lorenzo Da Dalt; Patrizia Uboldi; Fabrizia Bonacina; Andrés Fernando Muro; Giuseppe Danilo Norata
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HDL particles and infection-related death: when size matters

Cardiovascular Research
2023-05-02 | Journal article
DOI: 10.1093/cvr/cvad043
Contributors: Laura Calabresi; Giuseppe Danilo Norata
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Translational opportunities of single-cell biology in atherosclerosis

European Heart Journal
2023-04-07 | Journal article
DOI: 10.1093/eurheartj/ehac686
Contributors: Menno P J de Winther; Magnus Bäck; Paul Evans; Delphine Gomez; Isabel Goncalves; Helle F Jørgensen; Rory R Koenen; Esther Lutgens; Giuseppe Danilo Norata; Elena Osto et al.
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Vinculin phosphorylation modulates endothelial cell permeability: a new target for cardiovascular disease?

European Heart Journal
2023-01-21 | Journal article
DOI: 10.1093/eurheartj/ehac704
Contributors: Fabrizia Bonacina; Giuseppe Danilo Norata
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Mannose Receptor Deficiency Impacts Bone Marrow and Circulating Immune Cells during High Fat Diet Induced Obesity

Metabolites
2022-12 | Journal article | Author
DOI: 10.3390/metabo12121205
Contributors: Jasmine Nour; Annalisa Moregola; Monika Svecla; Lorenzo DA DALT; Rossella Bellini; Olivier Neyrolles; Gian Paolo Fadini; Yoann Rombouts ; Mattia Albiero; Fabrizia Bonacina et al.
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Multidisciplinary Digital Publishing Institute

Predictive value of HDL function in patients with coronary artery disease: relationship with coronary plaque characteristics and clinical events

Annals of Medicine
2022-12-31 | Journal article
DOI: 10.1080/07853890.2022.2063374
Part of ISSN: 0785-3890
Part of ISSN: 1365-2060
Contributors: Giuseppe Danilo Norata; Marco Magnoni; Daniele Andreini; Angela Pirillo; Patrizia Uboldi; Roberto Latini; Alberico L. Catapano; Aldo P. Maggioni; Giuseppe D. Norata; on behalf of the CAPIRE Study Group
Source: Self-asserted source
Giuseppe Danilo Norata

Pancreatic PCSK9 controls the organization of the β-cell secretory pathway via LDLR-cholesterol axis

Metabolism
2022-11 | Journal article
DOI: 10.1016/j.metabol.2022.155291
Part of ISSN: 0026-0495
Contributors: Giuseppe Danilo Norata; Algerta Marku; Lorenzo Da Dalt; Alessandra Galli; Nevia Dule; Paola Corsetto; Angela Maria Rizzo; Annalisa Moregola; Patrizia Uboldi; Fabrizia Bonacina et al.
Source: Self-asserted source
Giuseppe Danilo Norata

The low-density lipoprotein receptor–mTORC1 axis coordinates CD8+ T cell activation

Journal of Cell Biology
2022-11-07 | Journal article | Author
DOI: 10.1083/jcb.202202011
Part of ISSN: 0021-9525
Part of ISSN: 1540-8140
Contributors: Fabrizia Bonacina; Annalisa Moregola; Monika Svecla; David Coe; Patrizia Uboldi; Sara Fraire; Simona Beretta; Giangiacomo Beretta; Fabio Pellegatta; Alberico Luigi Catapano et al.
Source: Self-asserted source
Giuseppe Danilo Norata

Interleukin 1 Receptor 8 Deficiency Does not Impact Atherosclerosis

Thrombosis and Haemostasis
2022-10 | Journal article
DOI: 10.1055/a-1827-7205
Part of ISSN: 0340-6245
Part of ISSN: 2567-689X
Contributors: Giuseppe Danilo Norata; Jasmine Nour; Annalisa Moregola; Martina Molgora; Alberto Mantovani; Patrizia Uboldi; Alberico Luigi Catapano; Cecilia Garlanda; Fabrizia Bonacina; Giuseppe Danilo Norata
Source: Self-asserted source
Giuseppe Danilo Norata

Mature natural killer type 2 cells and experimental atherosclerosis

Atherosclerosis
2022-08 | Journal article
DOI: 10.1016/j.atherosclerosis.2022.06.294
Part of ISSN: 0021-9150
Contributors: J. Nour; F. Bonacina; A. Moregola; R. Bellini; C. Garlanda; A.L. Catapano; G.D. Norata
Source: Self-asserted source
Giuseppe Danilo Norata via Crossref Metadata Search

The low-density lipoprotein receptor fuels the cellular cholesterol-mTORC1 axis required for CD8+ T cell activation

Atherosclerosis
2022-08 | Journal article
DOI: 10.1016/j.atherosclerosis.2022.06.113
Part of ISSN: 0021-9150
Contributors: F. Bonacina; A. Moregola; D. Coe; M. Svecla; S. Fraire; G. Beretta; P. Uboldi; A.L. Catapano; F. Marelli-Berg; G.D. Norata
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Giuseppe Danilo Norata via Crossref Metadata Search

Lack of ApoA-I in ApoEKO Mice Causes Skin Xanthomas, Worsening of Inflammation, and Increased Coronary Atherosclerosis in the Absence of Hyperlipidemia

Arteriosclerosis, Thrombosis, and Vascular Biology
2022-07 | Journal article | Author
DOI: 10.1161/atvbaha.122.317790
Part of ISSN: 1079-5642
Part of ISSN: 1524-4636
Contributors: Marco Busnelli; Stefano Manzini; Alice Colombo; Elsa Franchi; Fabrizia Bonacina; MATTEO CHIARA; Francesca Arnaboldi; Elena Donetti; Federico Ambrogi; Roberto Oleari et al.
Source: Self-asserted source
Giuseppe Danilo Norata

Defective lipid signalling caused by mutations in <i>PIK3C2B</i> underlies focal epilepsy

Brain
2022-07-29 | Journal article
DOI: 10.1093/brain/awac082
Part of ISSN: 0006-8950
Part of ISSN: 1460-2156
Contributors: Giuseppe Danilo Norata; Luca Gozzelino; Gaga Kochlamazashvili; Sara Baldassari; Albert Ian Mackintosh; Laura Licchetta; Emanuela Iovino; Yu Chi Liu; Caitlin A Bennett; Mark Bennett et al.
Source: Self-asserted source
Giuseppe Danilo Norata

Crosstalk between dendritic cells and T lymphocytes during atherogenesis: Focus on antigen presentation and break of tolerance

Frontiers in Cardiovascular Medicine
2022-07-28 | Journal article
DOI: 10.3389/fcvm.2022.934314
Part of ISSN: 2297-055X
Contributors: Giuseppe Danilo Norata; Rossella Bellini; Fabrizia Bonacina; Giuseppe Danilo Norata
Source: Self-asserted source
Giuseppe Danilo Norata

Monocarboxylate transporter 1 deficiency impacts CD8+ T lymphocytes proliferation and recruitment to adipose tissue during obesity

iScience
2022-06 | Journal article
DOI: 10.1016/j.isci.2022.104435
Part of ISSN: 2589-0042
Contributors: Giuseppe Danilo Norata; C. Macchi; A. Moregola; M.F. Greco; M. Svecla; F. Bonacina; S. Dhup; R.K. Dadhich; M. Audano; P. Sonveaux et al.
Source: Self-asserted source
Giuseppe Danilo Norata

Rupatadine Treatment Is Associated with Atherosclerosis Worsening and Altered T Lymphocyte Recruitment

Thrombosis and Haemostasis
2022-05 | Journal article
DOI: 10.1055/a-1678-4031
Part of ISSN: 0340-6245
Part of ISSN: 2567-689X
Contributors: Giuseppe Danilo Norata; Marco Busnelli; Stefano Manzini; Alice Colombo; Fabrizia Bonacina; Giuseppe D. Norata; Elsa Franchi; Silvia Castiglioni; Christos Andronis; Eftychia Lekka et al.
Source: Self-asserted source
Giuseppe Danilo Norata

Loss of voltage-gated hydrogen channel 1 expression reveals heterogeneous metabolic adaptation to intracellular acidification by T cells

JCI Insight
2022-05-23 | Journal article | Author
DOI: 10.1172/jci.insight.147814
Part of ISSN: 2379-3708
Contributors: David Coe; Thanushiyan Poobalasingam; Hongmei Fu; Fabrizia Bonacina; Guosu Wang; Valle Morales; Annalisa Moregola; Nico Mitro; Kenneth C.P. Cheung; Eleanor J. Ward et al.
Source: Self-asserted source
Giuseppe Danilo Norata

Impact of metabolic disorders on the structural, functional, and immunological integrity of the blood‐brain barrier: Therapeutic avenues

The FASEB Journal
2022-01 | Journal article
DOI: 10.1096/fj.202101297r
Part of ISSN: 0892-6638
Part of ISSN: 1530-6860
Contributors: Giuseppe Danilo Norata; Madeeha H. Sheikh; Mariella Errede; Antonio d'Amati; Noorafza Q. Khan; Silvia Fanti; Rodrigo A. Loiola; Simon McArthur; Gareth S. D. Purvis; Caroline E. O'Riordan et al.
Source: Self-asserted source
Giuseppe Danilo Norata

Monoclonal Antibodies in the Management of Familial Hypercholesterolemia: Focus on PCSK9 and ANGPTL3 Inhibitors

Current Atherosclerosis Reports
2021-12 | Journal article
DOI: 10.1007/s11883-021-00972-x
Part of ISSN: 1523-3804
Part of ISSN: 1534-6242
Contributors: Giuseppe Danilo Norata; Angela Pirillo; Alberico L. Catapano; Giuseppe D. Norata
Source: Self-asserted source
Giuseppe Danilo Norata

In silico drug repurposing in COVID-19: A network-based analysis

Biomedicine &amp; Pharmacotherapy
2021-10 | Journal article
DOI: 10.1016/j.biopha.2021.111954
Part of ISSN: 0753-3322
Contributors: Giuseppe Danilo Norata; Pasquale Sibilio; Simone Bini; Giulia Fiscon; Marialuisa Sponziello; Federica Conte; Valeria Pecce; Cosimo Durante; Paola Paci; Rosa Falcone et al.
Source: Self-asserted source
Giuseppe Danilo Norata

DDASSQ: An open‐source, multiple peptide sequencing strategy for label free quantification based on an OpenMS pipeline in the KNIME analytics platform

PROTEOMICS
2021-08 | Journal article
DOI: 10.1002/pmic.202000319
Part of ISSN: 1615-9853
Part of ISSN: 1615-9861
Contributors: Giuseppe Danilo Norata; Monika Svecla; Giulia Garrone; Fiorenza Faré; Giacomo Aletti; Giuseppe Danilo Norata; Giangiacomo Beretta
Source: Self-asserted source
Giuseppe Danilo Norata

PCSK9 deficiency rewires heart metabolism and drives heart failure with preserved ejection fraction

European Heart Journal
2021-08-21 | Journal article | Author
DOI: 10.1093/eurheartj/ehab431
Part of ISSN: 0195-668X
Part of ISSN: 1522-9645
Contributors: Lorenzo DA DALT; Laura Castiglioni; Andrea Baragetti; Matteo Audano; Monika Svecla; Fabrizia Bonacina; Silvia Pedretti; Patrizia Uboldi; Patrizia Benzoni; FEDERICA GIANNETTI et al.
Source: Self-asserted source
Giuseppe Danilo Norata

A Synthetic Peptide Designed to Neutralize Lipopolysaccharides Attenuates Metaflammation and Diet-Induced Metabolic Derangements in Mice

Frontiers in Immunology
2021-07-19 | Journal article
DOI: 10.3389/fimmu.2021.701275
Part of ISSN: 1664-3224
Contributors: Giuseppe Danilo Norata; Shireen Mohammad; Sura Al Zoubi; Debora Collotta; Nadine Krieg; Bianka Wissuwa; Gustavo Ferreira Alves; Gareth S. D. Purvis; Giuseppe Danilo Norata; Andrea Baragetti et al.
Source: Self-asserted source
Giuseppe Danilo Norata

Effect of Lipids and Lipoproteins on Hematopoietic Cell Metabolism and Commitment in Atherosclerosis

Immunometabolism
2021-04 | Journal article
DOI: 10.20900/immunometab20210014
Part of ISSN: 2633-0407
Contributors: Andrea Baragetti; Fabrizia Bonacina; Alberico Luigi Catapano; Giuseppe Danilo Norata
Source: Self-asserted source
Giuseppe Danilo Norata via Crossref Metadata Search

Metabolomics, Lipidomics, and Immunometabolism

Methods in Molecular Biology
2021-04 | Other
DOI: 10.1007/978-1-0716-1311-5_24
Part of ISSN: 1064-3745
Contributors: Fortunata Carbone; Sara Bruzzaniti; Clorinda Fusco; Alessandra Colamatteo; Teresa Micillo; Paola De Candia; Fabrizia Bonacina; Giuseppe Danilo Norata; Giuseppe Matarese
Source: Self-asserted source
Giuseppe Danilo Norata via Crossref Metadata Search

HDL in Immune-Inflammatory Responses: Implications beyond Cardiovascular Diseases

Cells
2021-04-29 | Journal article | Author
DOI: 10.3390/cells10051061
Part of ISSN: 2073-4409
Contributors: Fabrizia Bonacina; Angela Pirillo; Alberico Luigi Catapano; Giuseppe Danilo Norata
Source: Self-asserted source
Giuseppe Danilo Norata
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Dyslipidaemia and regulatory T-cell migration: an immunometabolic connection?

Cardiovascular Research
2021-04-23 | Journal article
DOI: 10.1093/cvr/cvaa269
Contributors: Christoph Binder; Giuseppe Danilo Norata
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Global epidemiology of dyslipidaemias

Nature Reviews Cardiology
2021-04-08 | Journal article
DOI: 10.1038/s41569-021-00541-4
Part of ISSN: 1759-5002
Contributors: Angela Pirillo; Manuela Casula; Elena Olmastroni; Giuseppe D. Norata; Alberico L. Catapano
Source: Self-asserted source
Giuseppe Danilo Norata via Crossref Metadata Search

Impact of protein glycosylation on lipoprotein metabolism and atherosclerosis

Cardiovascular Research
2021-03-21 | Journal article
DOI: 10.1093/cvr/cvaa252
Contributors: Angela Pirillo; Monika Svecla; Alberico Luigi Catapano; Adriaan G Holleboom; Giuseppe Danilo Norata
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Crossref

Caloric Restriction Promotes Immunometabolic Reprogramming Leading to Protection from Tuberculosis

Cell Metabolism
2021-02 | Journal article
DOI: 10.1016/j.cmet.2020.12.016
Part of ISSN: 1550-4131
Contributors: Carla Palma; Claudia La Rocca; Vincenzo Gigantino; Gabriella Aquino; Giovanni Piccaro; Dario Di Silvestre; Francesca Brambilla; Rossana Rossi; Fabrizia Bonacina; Maria Teresa Lepore et al.
Source: Self-asserted source
Giuseppe Danilo Norata via Crossref Metadata Search

Metabolic adaptations of cells at the vascular-immune interface during atherosclerosis

Molecular Aspects of Medicine
2021-02 | Journal article
DOI: 10.1016/j.mam.2020.100918
Part of ISSN: 0098-2997
Contributors: F. Bonacina; L. Da Dalt; A.L. Catapano; G.D. Norata
Source: Self-asserted source
Giuseppe Danilo Norata via Crossref Metadata Search

Novel acquisitions in cell immunometabolism

Molecular Aspects of Medicine
2021-02 | Journal article
DOI: 10.1016/j.mam.2021.100945
Part of ISSN: 0098-2997
Contributors: Giuseppe Danilo Norata; Giuseppe Matarese
Source: Self-asserted source
Giuseppe Danilo Norata via Crossref Metadata Search

Gut Microbiota Functional Dysbiosis Relates to Individual Diet in Subclinical Carotid Atherosclerosis

Nutrients
2021-01 | Journal article | Author
DOI: 10.3390/nu13020304
Contributors: Andrea Baragetti; Marco Severgnini; Elena Olmastroni; Carola Conca Dioguardi; Elisa Mattavelli; andrea angius; Luca Rotta; Javier Cibella; Giada Caredda; Clarissa Consolandi et al.
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Multidisciplinary Digital Publishing Institute

Insights from ORION studies: focus on inclisiran safety

Cardiovascular Research
2021-01-01 | Journal article
DOI: 10.1093/cvr/cvaa139
Contributors: Alberico Luigi Catapano; Angela Pirillo; Giuseppe Danilo Norata
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Crossref

Recent insights into low-density lipoprotein metabolism and therapy

Current Opinion in Clinical Nutrition &amp; Metabolic Care
2020 | Journal article
DOI: 10.1097/mco.0000000000000727
Part of ISSN: 1363-1950
Contributors: Angela Pirillo; Alberico L. Catapano; Giuseppe D. Norata
Source: Self-asserted source
Giuseppe Danilo Norata via Crossref Metadata Search

Rivaroxaban improves vascular response in LPS-induced acute inflammation in experimental models

PLOS ONE
2020 | Journal article
DOI: 10.1371/journal.pone.0240669
Part of ISSN: 1932-6203
Contributors: Armond Daci; Lorenzo Da Dalt; Rame Alaj; Shpejtim Shurdhiqi; Burim Neziri; Rrahman Ferizi; Giuseppe Danilo Norata; Shaip Krasniqi; Xianwu Cheng
Source: Self-asserted source
Giuseppe Danilo Norata via Crossref Metadata Search
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