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Keywords

Computational Biology, Bioinformatics, Genetics, Genomics, Therapeutics, Machine Learning, Software Development, Database Development, Infectious Diseases, Primary Immunodeficiency

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United States

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Rockefeller University: New York, NY, US

Employment
Source: Self-asserted source
Peng Zhang

Works (50 of 85)

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Dexamethasone preconditioning may improve isoflurane-induced memory impairment by stabilising blood-brain barrier

Maejo International Journal of Science and Technology
2024 | Journal article
WOSUID: WOS:001150285800001
Contributors: Shao, Xueming; Li, Xiuxiu; Xu, Minhui; Xu, Fangxia; Zhang, Peng; Ma, Zhengliang; Xia, Tianjiao; Gu, Xiaoping
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Microstructure and properties of a shape memory alloy Ti-Ni-Al-V fabricated by double-wire arc additive manufacturing

Heliyon
2024 | Journal article
DOI: 10.1016/J.HELIYON.2024.E24347
WOSUID: WOS:001158765500001
Contributors: Zhao, Xiaoxin; Chen, Xinya; Ma, Tao; Zhang, Peng; Li, Jianguo; Zhang, Xin
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Quantitative patient graph analysis for transient ischemic attack risk factor distribution based on electronic medical records

Heliyon
2024 | Journal article
DOI: 10.1016/J.HELIYON.2023.E22766
WOSUID: WOS:001139999500001
Contributors: Wen, Jian; Zhang, Tianmei; Ye, Shangrong; Zhang, Peng; Han, Ruobing; Chen, Xiaowang; Huang, Ran; Chen, Anjun; Li, Qinghua
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The application of custom 3D-printed prostheses with ultra-short stems in the reconstruction of bone defects: a single center analysis

Frontiers in Bioengineering and Biotechnology
2024 | Journal article
DOI: 10.3389/FBIOE.2024.1349819
WOSUID: WOS:001157127700001
Contributors: Zhang, Peng; Tian, Wen; Li, Po; Zhang, Fan; Qu, Guoxin; Du, Xinhui; Liu, Guancong; Niu, Xiaoying
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Human inherited PD-L1 deficiency is clinically and immunologically less severe than PD-1 deficiency.

The Journal of experimental medicine
2024-04-18 | Journal article | Author
DOI: 10.1084/jem.20231704
PMID: 38634869
PMC: PMC11032109
Contributors: Matthew Johnson; Masato Ogishi; Clara Domingo-Vila; Elisa De Franco; Matthew Wakeling; imane zineb; Brittany Resnick; Evangelia Williams; Rui Galao; Richard Caswell et al.
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Peng Zhang

An immunogenomic exome landscape of triple positive primary antiphospholipid patients.

Genes and immunity
2024-01-24 | Journal article
DOI: 10.1038/s41435-024-00255-w
PMID: 38267542
Contributors: Guffroy A; Léa Jacquel; Seeleuthner Y; Nicodème Paul; Poindron V; Maurier F; Delannoy V; Voegeli AC; Zhang P; Nespola B et al.
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Peng Zhang

Autoantibodies against type I IFNs in humans with alternative NF-.B pathway deficiency

Nature
2023 | Journal article
DOI: 10.1038/S41586-023-06717-X
WOSUID: WOS:001169158300020
Contributors: Le Voyer, Tom; Parent, Audrey V.; Liu, Xian; Cederholm, Axel; Gervais, Adrian; Rosain, Jeremie; Nguyen, Tina; Lorenzo, Malena Perez; Rackaityte, Elze; Rinchai, Darawan et al.
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Bibliometric analysis of scientific publications on cryptorchidism: Research hotspots and trends between 2000 and 2022

Heliyon
2023 | Journal article
DOI: 10.1016/J.HELIYON.2023.E19722
WOSUID: WOS:001140647900001
Contributors: Xie, Xiaodu; Hu, Jian; Liu, Lumiao; Lei, Pan; Zhang, Peng; Ran, Chongjun; Liang, Peihe
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Disulfiram blocks inflammatory TLR4 signaling by targeting MD-2

Proceedings of the National Academy of Sciences
2023 | Journal article
DOI: 10.1073/PNAS.2306399120
WOSUID: WOS:001083489900004
Contributors: Bai, Yang; Min, Rui; Chen, Pengcheng; Mei, Shenglin; Deng, Fan; Zheng, Zengzhang; Jiang, Cong; Miao, Rui; Wu, Zeyu; Zhang, Peng et al.
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Exploring the role of differentially expressed metabolic genes and their mechanisms in bone metastatic prostate cancer

PeerJ
2023 | Journal article
DOI: 10.7717/PEERJ.15013
WOSUID: WOS:000996168400003
Contributors: Zhang, Qingfu; Zhang, Peng; Zhao, Zhongting; Wang, Jun; Zhang, Hepeng
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Genome-wide detection of human intronic AG-gain variants located between splicing branchpoints and canonical splice acceptor sites

Proceedings of the National Academy of Sciences
2023 | Journal article
DOI: 10.1073/PNAS.2314225120
WOSUID: WOS:001156414900004
Contributors: Zhang, Peng; Chaldebas, Matthieu; Ogishi, Masato; Al Qureshah, Fahd; Ponsin, Khoren; Feng, Yi; Rinchai, Darawan; Milisavljevic, Baptiste; Han, Ji Eun; Moncada-Velez, Marcela et al.
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Genotyping MUltiplexed-Sequencing of CRISPR-Localized Editing (GMUSCLE): An Experimental and Computational Approach for Analyzing CRISPR-Edited Cells

The CRISPR Journal
2023 | Journal article
DOI: 10.1089/CRISPR.2023.0021
WOSUID: WOS:001084424600006
Contributors: Zhang, Peng; Abel, Laurent; Casanova, Jean-Laurent; Yang, Rui
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Human IL-23 is essential for IFN-y-dependent immunity to mycobacteria

Science Immunology
2023 | Journal article
DOI: 10.1126/SCIIMMUNOLABQ5204
WOSUID: WOS:000964533700003
Contributors: Philippot, Quentin; Ogishi, Masato; Bohlen, Jonathan; Puchan, Julia; Arias, Andres Augusto; Nguyen, Tina; Martin-Fernandez, Marta; Conil, Clement; Rinchai, Darawan; Momenilandi, Mana et al.
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Identifying high-impact variants and genes in exomes of Ashkenazi Jewish inflammatory bowel disease patients

Nature Communications
2023 | Journal article
DOI: 10.1038/S41467-023-37849-3
WOSUID: WOS:001025823500001
Contributors: Wu, Yiming; Gettler, Kyle; Kars, Meltem Ece; Giri, Mamta; Li, Dalin; Bayrak, Cigdem Sevim; Zhang, Peng; Jain, Aayushee; Maffucci, Patrick; Sabic, Ksenija et al.
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Salinity-mediated water self-purification via bond network distorting of H<sub>2</sub>O molecules on DRC-surface

Proceedings of the National Academy of Sciences
2023 | Journal article
DOI: 10.1073/PNAS.2311920120
WOSUID: WOS:001138999200005
Contributors: Cao, Wenrui; Hu, Chun; Zhang, Peng; Qiu, Ting; Wang, Shuguang; Huang, Guohe; Lyu, Lai
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Human MCTS1-dependent translation of JAK2 is essential for IFN-γ immunity to mycobacteria.

Cell
2023-10-23 | Journal article
DOI: 10.1016/j.cell.2023.09.024
PMID: 37875108
PMC: PMC10841658
Contributors: Jonathan Bohlen; Zhou Q; Philippot Q; Masato Ogishi; Darawan Rinchai; Nieminen T; Seyedpour S; Parvaneh N; Rezaei N; Yazdanpanah N et al.
Source: Self-asserted source
Peng Zhang

Human RELA dominant-negative mutations underlie type I interferonopathy with autoinflammation and autoimmunity.

The Journal of experimental medicine
2023-06-05 | Journal article | Author
DOI: 10.1084/jem.20212276
PMID: 37273177
PMC: PMC10242411
Contributors: Kunihiko Moriya; Tomohiro Nakano; Yoshitaka Honda; Miyuki Tsumura; Masato Ogishi; Motoshi Sonoda; Masahiko Nishitani-Isa; Takashi Uchida; Hbibi M; Yoko Mizoguchi et al.
Source: Self-asserted source
Peng Zhang

Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19.

Genome medicine
2023-04-05 | Journal article
DOI: 10.1186/s13073-023-01173-8
PMID: 37020259
PMC: PMC10074346
Contributors: Matuozzo D; Talouarn E; Marchal A; Zhang P; Manry J; Seeleuthner Y; Zhang Y; Bolze A; Chaldebas M; Milisavljevic B et al.
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Peng Zhang

Human IRF1 governs macrophagic IFN-γ immunity to mycobacteria

Cell
2023-02 | Journal article
DOI: 10.1016/j.cell.2022.12.038
Part of ISSN: 0092-8674
Contributors: Jérémie Rosain; Anna-Lena Neehus; Jérémy Manry; Rui Yang; Jérémie Le Pen; Wassim Daher; Zhiyong Liu; Yi-Hao Chan; Natalia Tahuil; Özden Türel et al.
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Peng Zhang
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Human IL-23 is essential for IFN-γ–dependent immunity to mycobacteria

Science Immunology
2023-02-24 | Journal article | Author
DOI: 10.1126/sciimmunol.abq5204
Part of ISSN: 2470-9468
Contributors: Quentin Philippot; Masato Ogishi; Jonathan Bohlen; Julia Puchan; Arias AA; Tina Nguyen ; Marta Martín-Fernández; Clement Conil; Darawan Rinchai; Mana Momenilandi et al.
Source: Self-asserted source
Peng Zhang

Genome-wide detection of human variants that disrupt intronic branchpoints

Proceedings of the National Academy of Sciences
2022 | Journal article
DOI: 10.1073/PNAS.2211194119
WOSUID: WOS:000964703700010
Contributors: Zhang, Peng; Philippot, Quentin; Ren, Weicheng; Lei, Wei-Te; Li, Juan; Stenson, Peter D.; Palacin, Pere Soler; Colobran, Roger; Boisson, Bertrand; Zhang, Shen-Ying et al.
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Impaired IL-23-dependent induction of IFN-γ underlies mycobacterial disease in patients with inherited TYK2 deficiency

Journal of Experimental Medicine
2022 | Journal article
DOI: 10.1084/JEM.20220094
WOSUID: WOS:000892570400001
Contributors: Ogishi, Masato; Augusto Arias, Andres; Yang, Rui; Han, Ji Eun; Zhang, Peng; Rinchai, Darawan; Halpern, Joshua; Mulwa, Jeanette; Keating, Narelle; Chrabieh, Maya et al.
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Respiratory viral infections in otherwise healthy humans with inherited IRF7 deficiency

Journal of Experimental Medicine
2022 | Journal article
DOI: 10.1084/JEM.20220202
WOSUID: WOS:000868242500001
Contributors: Campbell, Tessa Mollie; Liu, Zhiyong; Zhang, Qian; Moncada-Velez, Marcela; Covill, Laura E.; Zhang, Peng; Darazam, Ilad Alavi; Bastard, Paul; Bizien, Lucy; Bucciol, Giorgia et al.
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The antioxidant system response to drought-stressed<i> Diospyros</i><i> lotus</i> treated with exogenous melatonin

PeerJ
2022 | Journal article
DOI: 10.7717/PEERJ.13936
WOSUID: WOS:000862803600002
Contributors: Zhang, Peng; Hu, Yi; Zhou, Ruijin; Zhang, Xiaona; Hu, Huiling; Lang, Dongmei
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Inborn errors of OAS–RNase L in SARS-CoV-2–related multisystem inflammatory syndrome in children

Science
2022-12-20 | Journal article
DOI: 10.1126/science.abo3627
Part of ISSN: 0036-8075
Part of ISSN: 1095-9203
Contributors: Danyel Lee; Jérémie Le Pen; Ahmad Yatim; Beihua Dong; Yann Aquino; Masato Ogishi; Rémi Pescarmona; Estelle Talouarn; Darawan Rinchai; Peng Zhang et al.
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Peng Zhang
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Human OTULIN haploinsufficiency impairs cell-intrinsic immunity to staphylococcal α-toxin

Science
2022-06-17 | Journal article | Author
DOI: 10.1126/science.abm6380
Part of ISSN: 0036-8075
Part of ISSN: 1095-9203
Contributors: András Spaan; Anna-Lena Neehus; Emmanuel LAPLANTINE; Frederik Staels; Masato Ogishi; Yoann Seeleuthner; Franck Rapaport; Keenan A. Lacey; Erika Van Nieuwenhove; Maya Chrabieh et al.
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Peng Zhang
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Inherited IFNAR1 Deficiency in a Child with Both Critical COVID-19 Pneumonia and Multisystem Inflammatory Syndrome

Journal of Clinical Immunology
2022-04 | Journal article
DOI: 10.1007/s10875-022-01215-7
Part of ISSN: 0271-9142
Part of ISSN: 1573-2592
Contributors: Hassan Abolhassani; Nils Landegren; Paul Bastard; Marie Materna; Mohammadreza Modaresi; Likun Du; Maribel Aranda-Guillén; Fabian Sardh; Fanglei Zuo; Peng Zhang et al.
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Peng Zhang
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Human genetic and immunological determinants of critical COVID-19 pneumonia

Nature
2022-03-24 | Journal article
DOI: 10.1038/s41586-022-04447-0
Part of ISSN: 0028-0836
Part of ISSN: 1476-4687
Contributors: Qian Zhang; Paul Bastard; Adem Karbuz; Adrian Gervais; Ahmad Abou Tayoun; Alessandro Aiuti; Alexandre Belot; Alexandre Bolze; Alexandre Gaudet; Anastasiia Bondarenko et al.
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Peng Zhang

A computational approach for detecting physiological homogeneity in the midst of genetic heterogeneity

The American Journal of Human Genetics
2021 | Journal article
DOI: 10.1016/J.AJHG.2021.04.023
WOSUID: WOS:000658897400002
Contributors: Zhang, Peng; Cobat, Aurelie; Lee, Yoon-Seung; Wu, Yiming; Bayrak, Cigdem Sevim; Boccon-Gibod, Clementine; Matuozzo, Daniela; Lorenzo, Lazaro; Jain, Aayushee; Boucherit, Soraya et al.
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Monoclonal antibody-mediated neutralization of SARS-CoV-2 in an IRF9-deficient child

Proceedings of the National Academy of Sciences
2021 | Journal article
DOI: 10.1073/PNAS.2114390118
WOSUID: WOS:000720926500002
Contributors: Levy, Romain; Zhang, Peng; Bastard, Paul; Dorgham, Karim; Melki, Isabelle; Hadchouel, Alice; Hartoularos, George C.; Neven, Benedicte; Castelle, Martin; Roy, Charlotte et al.
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X-linked recessive TLR7 deficiency in ∼1% of men under 60 years old with life-threatening COVID-19

Science Immunology
2021 | Journal article
DOI: 10.1126/SCIIMMUNOL.ABL4348
WOSUID: WOS:000695969700003
Contributors: Asano, Takaki; Boisson, Bertrand; Onodi, Fanny; Matuozzo, Daniela; Moncada-Velez, Marcela; Renkilaraj, Majistor Raj Luxman Maglorius; Zhang, Peng; Meertens, Laurent; Bolze, Alexandre; Materna, Marie et al.
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Biochemically deleterious human NFKB1 variants underlie an autosomal dominant form of common variable immunodeficiency

Journal of Experimental Medicine
2021-11-01 | Journal article
DOI: 10.1084/jem.20210566
Contributors: Juan Li; Wei-Te Lei; Peng Zhang; Franck Rapaport; Yoann Seeleuthner; Bingnan Lyu; Takaki Asano; Jérémie Rosain; Boualem Hammadi; Yu Zhang et al.
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Protein music of enhanced musicality by music style guided exploration of diverse amino acid properties

Heliyon
2021-09 | Journal article
DOI: 10.1016/j.heliyon.2021.e07933
Part of ISSN: 2405-8440
Source: Self-asserted source
Peng Zhang

Type I interferon autoantibodies are associated with systemic immune alterations in patients with COVID-19.

Science translational medicine
2021-08-24 | Journal article
DOI: 10.1126/scitranslmed.abh2624
PMID: 34429372
Source: Self-asserted source
Peng Zhang

Human STAT3 variants underlie autosomal dominant hyper-IgE syndrome by negative dominance

Journal of Experimental Medicine
2021-08-02 | Journal article
DOI: 10.1084/jem.20202592
Contributors: Takaki Asano; Joëlle Khourieh; Peng Zhang; Franck Rapaport; András N. Spaan; Juan Li; Wei-Te Lei; Simon J. Pelham; David Hum; Maya Chrabieh et al.
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Inherited PD-1 deficiency underlies tuberculosis and autoimmunity in a child.

Nature medicine
2021-06-28 | Journal article
DOI: 10.1038/s41591-021-01388-5
PMID: 34183838
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Peng Zhang
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SARS-CoV-2-related MIS-C: A key to the viral and genetic causes of Kawasaki disease?

The Journal of experimental medicine
2021-06-01 | Journal article
DOI: 10.1084/jem.20210446
PMID: 33904890
PMC: PMC8080850
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Peng Zhang

TLR3 controls constitutive IFN-β antiviral immunity in human fibroblasts and cortical neurons

Journal of Clinical Investigation
2021-01-04 | Journal article
DOI: 10.1172/JCI134529
Contributors: Daxing Gao; Michael J. Ciancanelli; Peng Zhang; Oliver Harschnitz; Vincent Bondet; Mary Hasek; Jie Chen; Xin Mu; Yuval Itan; Aurélie Cobat et al.
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Herpes simplex encephalitis in a patient with a distinctive form of inherited IFNAR1 deficiency.

The Journal of clinical investigation
2021-01-01 | Journal article
DOI: 10.1172/jci139980
PMID: 32960813
PMC: PMC7773360
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Peng Zhang
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Human T-bet Governs Innate and Innate-like Adaptive IFN-γ Immunity against Mycobacteria

Cell
2020 | Journal article
DOI: 10.1016/J.CELL.2020.10.046
WOSUID: WOS:000602900800009
Contributors: Yang, Rui; Mele, Federico; Worley, Lisa; Langlais, David; Rosain, Jeremie; Benhsaien, Ibithal; Elarabi, Houda; Croft, Carys A.; Doisne, Jean-Marc; Zhang, Peng et al.
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Life-Threatening COVID-19: Defective Interferons Unleash Excessive Inflammation.

Med (New York, N.Y.)
2020-12-01 | Journal article
DOI: 10.1016/j.medj.2020.12.001
PMID: 33363283
PMC: PMC7748410
Source: Self-asserted source
Peng Zhang

Multibatch Cytometry Data Integration for Optimal Immunophenotyping.

Journal of immunology (Baltimore, Md. : 1950)
2020-11-23 | Journal article
DOI: 10.4049/jimmunol.2000854
PMID: 33229441
Source: Self-asserted source
Peng Zhang

Autoantibodies against type I IFNs in patients with life-threatening COVID-19.

Science (New York, N.Y.)
2020-09-24 | Journal article
DOI: 10.1126/science.abd4585
PMID: 32972996
PMC: PMC7857397
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Peng Zhang
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Inborn errors of type I IFN immunity in patients with life-threatening COVID-19.

Science (New York, N.Y.)
2020-09-24 | Journal article
DOI: 10.1126/science.abd4570
PMID: 32972995
PMC: PMC7857407
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Peng Zhang
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De novo variants in exomes of congenital heart disease patients identify risk genes and pathways.

Genome medicine
2020-01-15 | Journal article
DOI: 10.1186/s13073-019-0709-8
PMID: 31941532
PMC: PMC6961332
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Peng Zhang
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Biological Network Approaches and Applications in Rare Disease Studies

Genes
2019 | Journal article
DOI: 10.3390/GENES10100797
WOSUID: WOS:000498397100068
Contributors: Zhang, Peng; Itan, Yuval
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SeqTailor: a user-friendly webserver for the extraction of DNA or protein sequences from next-generation sequencing data

Nucleic Acids Research
2019 | Journal article
DOI: 10.1093/NAR/GKZ326
WOSUID: WOS:000475901600093
Contributors: Zhang, Peng; Boisson, Bertrand; Stenson, Peter D.; Cooper, David N.; Casanova, Jean-Laurent; Abel, Laurent; Itan, Yuval
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Human SNORA31 variations impair cortical neuron-intrinsic immunity to HSV-1 and underlie herpes simplex encephalitis.

Nature medicine
2019-12-05 | Journal article
DOI: 10.1038/s41591-019-0672-3
PMID: 31806906
PMC: PMC7376819
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Peng Zhang
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CMAUP: a database of collective molecular activities of useful plants.

Nucleic acids research
2019-01-01 | Journal article
DOI: 10.1093/nar/gky965
PMID: 30357356
PMC: PMC6324012
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Peng Zhang
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PopViz: a webserver for visualizing minor allele frequencies and damage prediction scores of human genetic variations

Bioinformatics
2018 | Journal article
DOI: 10.1093/BIOINFORMATICS/BTY536
WOSUID: WOS:000454278000025
Contributors: Zhang, Peng; Bigio, Benedetta; Rapaport, Franck; Zhang, Shen-Ying; Casanova, Jean-Laurent; Abel, Laurent; Boisson, Bertrand; Itan, Yuval
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