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Employment (2)

Max Planck Institute for Molecular Biomedicine: Münster, Nordrhein-Westfalen, DE

2020-11 to present | Postdoc (Hans R. Schöler)
Employment
Source: Self-asserted source
Sergiy Velychko

Max Planck Institute for Molecular Biomedicine: Münster, Nordrhein-Westfalen, DE

2012-10 to 2020-10 | PhD student (Hans R. Schöler)
Employment
Source: Self-asserted source
Sergiy Velychko

Education and qualifications (3)

Max Planck Institute for Molecular Biomedicine: Münster, Nordrhein-Westfalen, DE

2012-10 to 2020-11 | PhD in Biology (Cell and Developmental Biology)
Education
Source: Self-asserted source
Sergiy Velychko

Technische Universität Dresden: Dresden, Sachsen, DE

2010-10 to 2012-09 | Master of Science in Molecular Bioengineering (BIOTEC)
Education
Source: Self-asserted source
Sergiy Velychko

Kyyivs'kij nacional'nij universytet imeni Tarasa Shevchenka: Kyiv, UA

2006 to 2010 | Bachelor of Science in Biology (Biology, Biochemistry, Biotechnology)
Education
Source: Self-asserted source
Sergiy Velychko

Works (20)

Emerging cooperativity between Oct4 and Sox2 governs the pluripotency network in early mouse embryos

eLife
2025-02-27 | Journal article
DOI: 10.7554/eLife.100735.3
Contributors: Yanlin Hou; Zhengwen Nie; Qi Jiang; Sergiy Velychko; Sandra Heising; Ivan Bedzhov; Guangming Wu; Kenjiro Adachi; Hans R Scholer
Source: check_circle
Crossref

Emerging cooperativity between Oct4 and Sox2 governs the pluripotency network in early mouse embryos

eLife
2025-02-27 | Journal article
DOI: 10.7554/eLife.100735
Contributors: Yanlin Hou; Zhengwen Nie; Qi Jiang; Sergiy Velychko; Sandra Heising; Ivan Bedzhov; Guangming Wu; Kenjiro Adachi; Hans R Scholer
Source: check_circle
Crossref

Rapid human oogonia-like cell specification via transcription factor-directed differentiation

EMBO Reports
2025-01-23 | Journal article
DOI: 10.1038/s44319-025-00371-2
Contributors: Merrick Pierson Smela; Christian C Kramme; Patrick R J Fortuna; Bennett Wolf; Shrey Goel; Jessica Adams; Carl Ma; Sergiy Velychko; Ursula Widocki; Venkata Srikar Kavirayuni et al.
Source: check_circle
Crossref

Emerging cooperativity between Oct4 and Sox2 governs the pluripotency network in early mouse embryos

2025-01-15 | Preprint
DOI: 10.7554/eLife.100735.2
Contributors: Yanlin Hou; Zhengwen Nie; Qi Jiang; Sergiy Velychko; Sandra Heising; Ivan Bedzhov; Guangming Wu; Kenjiro Adachi; Hans R Schöler
Source: check_circle
Crossref

Emerging cooperativity between Oct4 and Sox2 governs the pluripotency network in mouse early embryos

2024-10-11 | Preprint
DOI: 10.7554/eLife.100735.1
Contributors: Yanlin Hou; Zhengwen Nie; Qi Jiang; Sergiy Velychko; Sandra Heising; Ivan Bedzhov; Guangming Wu; Kenjiro Adachi; Hans R Schöler
Source: check_circle
Crossref

Sendai virus persistence questions the transient naive reprogramming method for iPSC generation

2024-03-12 | Preprint
DOI: 10.1101/2024.03.07.583804
Contributors: Alejandro De Los Angeles; Clemens B. Hug; Vadim N. Gladyshev; George M. Church; Sergiy Velychko
Source: check_circle
Crossref

Emerging cooperativity between Oct4 and Sox2 governs the pluripotency network in early mouse embryos

2023-10-21 | Preprint
DOI: 10.1101/2023.10.18.562912
Contributors: Yanlin Hou; Zhengwen Nie; Qi Jiang; Sergiy Velychko; Sandra Heising; Ivan Bedzhov; Guangming Wu; Kenjiro Adachi; Hans R. Schöler
Source: check_circle
Crossref

Enhancing Sox/Oct cooperativity induces higher-grade developmental reset

2022-09-25 | Preprint
DOI: 10.1101/2022.09.23.509242
Contributors: Caitlin M. MacCarthy; Vikas Malik; Guangming Wu; Taras Velychko; Gal Keshet; Ralf Jauch; Vlad Cojocaru; Hans R. Schöler; Sergiy Velychko
Source: check_circle
Crossref

Oct4 differentially regulates chromatin opening and enhancer transcription in pluripotent stem cells

eLife
2022-05-27 | Journal article
DOI: 10.7554/eLife.71533
Contributors: Le Xiong; Erik A Tolen; Jinmi Choi; Sergiy Velychko; Livia Caizzi; Taras Velychko; Kenjiro Adachi; Caitlin M MacCarthy; Michael Lidschreiber; Patrick Cramer et al.
Source: check_circle
Crossref

One-step Reprogramming of Human Fibroblasts into Oligodendrocyte-like Cells by SOX10, OLIG2, and NKX6.2

Stem Cell Reports
2021-04 | Journal article
DOI: 10.1016/j.stemcr.2021.03.001
Part of ISSN: 2213-6711
Source: Self-asserted source
Sergiy Velychko

Directed evolution of an enhanced POU reprogramming factor for cell fate engineering

Molecular biology and evolution
2021-03-15 | Journal article
DOI: 10.1093/molbev/msab075
PMID: 33720298
Source: Self-asserted source
Sergiy Velychko

Reprogramming competence of OCT factors is determined by transactivation domains

Science Advances
2020-09-04 | Journal article
DOI: 10.1126/sciadv.aaz7364
Contributors: Kee-Pyo Kim; You Wu; Juyong Yoon; Kenjiro Adachi; Guangming Wu; Sergiy Velychko; Caitlin M. MacCarthy; Borami Shin; Albrecht Röpke; Marcos J. Arauzo-Bravo et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

R-loops coordinate with SOX2 in regulating reprogramming to pluripotency

Science Advances
2020-06-12 | Journal article
DOI: 10.1126/sciadv.aba0777
Contributors: Yaoyi Li; Yawei Song; Wei Xu; Qin Li; Xinxiu Wang; Kuan Li; Juehan Wang; Zicong Liu; Sergiy Velychko; Rong Ye et al.
Source: check_circle
Crossref

Pluripotency reprogramming by competent and incompetent POU factors uncovers temporal dependency for Oct4 and Sox2

Nature Communications
2019-12 | Journal article
DOI: 10.1038/s41467-019-11054-7
Part of ISSN: 2041-1723
Source: Self-asserted source
Sergiy Velychko

Excluding Oct4 from Yamanaka Cocktail Unleashes the Developmental Potential of iPSCs

Cell stem cell
2019-11-07 | Journal article
DOI: 10.1016/j.stem.2019.10.002
PMID: 31708402
PMC: PMC6900749
Source: Self-asserted source
Sergiy Velychko

Fusion of Reprogramming Factors Alters the Trajectory of Somatic Lineage Conversion

Cell Reports
2019-04 | Journal article
DOI: 10.1016/j.celrep.2019.03.023
Part of ISSN: 2211-1247
Source: Self-asserted source
Sergiy Velychko

Changing POU dimerization preferences converts Oct6 into a pluripotency inducer.

2017-02 | Journal article
DOI: 10.15252/embr.201642958
PMID: 28007765
PMC: PMC5286379
Contributors: Jerabek S; Ng CK; Wu G; Arauzo-Bravo MJ; Kim KP; Esch D; Malik V; Chen Y; Velychko S; MacCarthy CM et al.
Source: Self-asserted source
Sergiy Velychko via Europe PubMed Central

Rapid and efficient generation of oligodendrocytes from human induced pluripotent stem cells using transcription factors.

2017-02 | Journal article
DOI: 10.1073/pnas.1614412114
PMID: 28246330
Contributors: Ehrlich M; Mozafari S; Glatza M; Starost L; Velychko S; Hallmann AL; Cui QL; Schambach A; Kim KP; Bachelin C et al.
Source: Self-asserted source
Sergiy Velychko via Europe PubMed Central

Functional Restoration of gp91phox-Oxidase Activity by BAC Transgenesis and Gene Targeting in X-linked Chronic Granulomatous Disease iPSCs.

2016-04 | Journal article
DOI: 10.1038/mt.2015.154
PMID: 26316390
PMC: PMC4886927
Contributors: Laugsch M; Rostovskaya M; Velychko S; Richter C; Zimmer A; Klink B; Schröck E; Haase M; Neumann K; Thieme S et al.
Source: Self-asserted source
Sergiy Velychko via Europe PubMed Central

Enhanced OCT4 transcriptional activity substitutes for exogenous SOX2 in cellular reprogramming.

2016-01 | Journal article
DOI: 10.1038/srep19415
PMID: 26762895
PMC: PMC4725906
Contributors: Marthaler AG; Adachi K; Tiemann U; Wu G; Sabour D; Velychko S; Kleiter I; Schöler HR; Tapia N
Source: Self-asserted source
Sergiy Velychko via Europe PubMed Central

Peer review (1 review for 1 publication/grant)

Review activity for Nature communications (1)
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