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Aarhus University: Aarhus C, DK

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Aarhus University

Works (31)

T-follicular regulatory cells expand to control germinal center plasma cell output but fail to curb autoreactivity

iScience
2024-10 | Journal article | Author
DOI: 10.1016/j.isci.2024.110887
SOURCE-WORK-ID:

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EID:

2-s2.0-85207788889

PMID: 39319261
Contributors: Cecilia Fahlquist-Hagert; Thomas Rea Wittenborn; Mattias Krogh Pedersen; Lisbeth Jensen; Søren Egedal Degn
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Aarhus University

Haplosufficiency of MHCII in autoreactive germinal center B cells

European Journal of Immunology
2024-01 | Journal article
DOI: 10.1002/eji.202350422
Contributors: Cecilia Fahlquist‐Hagert; Thomas R. Wittenborn; Alexey Ferapontov; Lisbeth Jensen; Ewa Terczyńska‐Dyla; Søren E. Degn
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Crossref
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B cell MHC haplotype affects follicular inclusion, germinal center participation and plasma cell differentiation in a mouse model of lupus

Frontiers in Immunology
2023 | Journal article
DOI: 10.3389/fimmu.2023.1258046
EID:

2-s2.0-85179342847

Part of ISSN: 16643224
Contributors: Wibrand, C.; Wittenborn, T.R.; Voss, L.F.; Winther, G.; Jensen, L.; Ferapontov, A.; Fonager, S.V.; Fahlquist-Hagert, C.; Degn, S.E.
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Thomas Rea Wittenborn via Scopus - Elsevier

Antigen presentation by B cells enables epitope spreading across an MHC barrier

Nature Communications
2023-12 | Journal article | Author
DOI: 10.1038/s41467-023-42541-7
SOURCE-WORK-ID:

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EID:

2-s2.0-85175556383

PMID: 37907556
Contributors: Cecilia Fahlquist-Hagert; Thomas Rea Wittenborn; Ewa Terczyńska-Dyla; Kristian Savstrup Kastberg; Emily Yang; Alysa Nicole Rallistan; Quinton Raymond Markett; Gudrun Winther; Sofie Fonager; Lasse F. Voss et al.
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Aarhus University
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The effect of single bout and prolonged aerobic exercise on tumor hypoxia in mice

Journal of Applied Physiology
2023-03 | Journal article | Author
DOI: 10.1152/japplphysiol.00561.2022
SOURCE-WORK-ID:

a96bde8e-ce38-40ae-87d5-d963088e473f

PMID: 36727633
EID:

2-s2.0-85150311375
Contributors: Pernille Byrialsen Elming; Morten Busk; Thomas Rea Wittenborn; Johan Bussink; Michael R Horsman; Simon Lønbro
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Aarhus University
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The extrafollicular response is sufficient to drive initiation of autoimmunity and early disease hallmarks of lupus

Frontiers in Immunology
2022-12-14 | Journal article | Author
DOI: 10.3389/fimmu.2022.1021370
SOURCE-WORK-ID:

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PMID: 36591222
EID:

2-s2.0-85145075196

PMID: 36591222
Contributors: Lasse F. Voss; Amanda J. Howarth; Thomas Rea Wittenborn; Sandra Hummelgaard; Kristian Juul-Madsen; Kristian S. Kastberg; Mathias K. Pedersen; Lisbeth Jensen; Anastasios D. Papanastasiou; Thomas Vorup-Jensen et al.
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Aarhus University
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Increased maternofoetal transfer of antibodies in a murine model of systemic lupus erythematosus, but no immune activation and neuroimmune sequelae in offspring

Journal of Neuroimmunology
2022-09-15 | Journal article | Author
DOI: 10.1016/j.jneuroim.2022.577927
SOURCE-WORK-ID:

5e13c1cc-0e1d-4d3c-9a81-c7c6d064d5ae

PMID: 35858501
EID:

2-s2.0-85134172836
Contributors: Sofie Vestergaard Fonager; Gudrun Winther; Thomas Rea Wittenborn; Lisbeth Jensen; Cecilia Fahlquist-Hagert; Lisbeth Ahm Hansen; Ernst-Martin Füchtbauer; Marina Romero-Ramos; Søren Egedal Degn
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Aarhus University
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Extrafollicular responses are sufficient to drive initiation of autoimmunity and early disease hallmarks of lupus

2022-03-04 | Preprint
DOI: 10.1101/2022.03.04.482991
Contributors: Lasse F. Voss; Amanda J. Howarth; Thomas R. Wittenborn; Sandra Hummelgaard; Kristian Juul-Madsen; Kristian S. Kastberg; Mathias K. Pedersen; Lisbeth Jensen; Anastasios D. Papanastasiou; Thomas Vorup-Jensen et al.
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Crossref
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B Cell Intrinsic STING Signaling Is Not Required for Autoreactive Germinal Center Participation

Frontiers in Immunology
2021-12 | Journal article | Author
DOI: 10.3389/fimmu.2021.782558
SOURCE-WORK-ID:

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EID:

2-s2.0-85121987634

PMID: 34938294
Contributors: Kenneth Green; Thomas Rea Wittenborn; Cecilia Fahlquist-Hagert; Ewa Terczynska-Dyla; Nina van Campen; Lisbeth Jensen; Line Reinert; Rune Hartmann; Søren R. Paludan; Søren Egedal Degn
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Aarhus University
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Characterization of DNA-protein complexes by nanoparticle tracking analysis and their association with systemic lupus erythematosus

Proceedings of the National Academy of Sciences (PNAS)
2021-07 | Journal article | Author
DOI: 10.1073/pnas.2106647118
SOURCE-WORK-ID:

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PMID: 34301873
EID:

2-s2.0-85110982238

WOSUID:

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Contributors: Kristian Juul-Madsen; Anne Troldborg; Thomas Rea Wittenborn; Mads G Axelsen; Huaying Zhao; Lasse Hyldgaard Klausen; Stefanie Luecke; Søren R Paludan; Kristian Stengaard-Pedersen; Mingdong Dong et al.
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Aarhus University
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Refinement of an established procedure and its application for identification of hypoxia in prostate cancer xenografts

Cancers
2021-06 | Journal article | Author
DOI: 10.3390/cancers13112602
SOURCE-WORK-ID:

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EID:

2-s2.0-85106447080

PMID: 34073301
Contributors: Pernille B. Elming; Thomas Rea Wittenborn; Morten Busk; Brita Singers Sørensen; Mathilde Borg Houlberg Thomsen; Trine Strandgaard; Lars Dyrskjøt; Steffen Nielsen; Michael R. Horsman
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Aarhus University
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Comparison of gamma and x-ray irradiation for myeloablation and establishment of normal and autoimmune syngeneic bone marrow chimeras

PLOS ONE
2021-03 | Journal article | Author
DOI: 10.1371/journal.pone.0247501
SOURCE-WORK-ID:

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EID:

2-s2.0-85102756340

PMID: 33730087
Contributors: Thomas Rea Wittenborn; Cecilia Fahlquist Hagert; Alexey Ferapontov; Sofie Fonager; Lisbeth Jensen; Gudrun Winther; Søren Egedal Degn
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Seeing the Confetti Colors in a New Light Utilizing Flow Cytometry and Imaging Flow Cytometry

Cytometry. Part A
2020-08-01 | Journal article | Author
DOI: 10.1002/cyto.a.24032
SOURCE-WORK-ID:

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PMID: 32459058
EID:

2-s2.0-85086159032

WOSUID:

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Contributors: Cecilia Fahlquist Hagert; Anja Bille Bohn; Thomas Rea Wittenborn; Søren Egedal Degn
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Aarhus University
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Tumors resistant to checkpoint inhibitors can become sensitive after treatment with vascular disrupting agents

International Journal of Molecular Sciences
2020-07 | Journal article | Author
DOI: 10.3390/ijms21134778
SOURCE-WORK-ID:

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EID:

2-s2.0-85087460806

PMID: 32640548
Contributors: Michael R. Horsman; Thomas Rea Wittenborn; Patricia Switten Nielsen; Pernille B. Elming
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Aarhus University
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Reliability of blood lactate as a measure of exercise intensity in different strains of mice during forced treadmill running

PLOS ONE
2019-05-07 | Journal article | Author
DOI: 10.1371/journal.pone.0215584
SOURCE-WORK-ID:

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EID:

2-s2.0-85065578063

PMID: 31050686
Contributors: Simon Lønbro; Jennifer M. Wiggins; Thomas Rea Wittenborn; Pernille Byrialsen Elming; Lori Rice; Christine Pampo; Jennifer A. Lee; Dietmar W. Siemann; Michael R. Horsman
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Aarhus University
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Interrogating Individual Autoreactive Germinal Centers by Photoactivation in a Mixed Chimeric Model of Autoimmunity

Journal of visualized experiments : JoVE
2019-04 | Journal article | Author
DOI: 10.3791/59397
SOURCE-WORK-ID:

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EID:

2-s2.0-85065413206

PMID: 31033960
Contributors: Thomas Rea Wittenborn; Cecilia Hagert; Søren Egedal Degn
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Aarhus University
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The potential of hyperpolarized (13)C magnetic resonance spectroscopy to monitor the effect of combretastatin based vascular disrupting agents

Acta Oncologica
2017-11-02 | Journal article | Author
DOI: 10.1080/0284186X.2017.1351622
SOURCE-WORK-ID:

d2280cbf-1474-4373-8ef0-d6df3370ab25

PMID: 28840759
EID:

2-s2.0-85028551524
Contributors: Ane B Iversen; Morten Busk; Lotte B Bertelsen; Christoffer Laustsen; Ole Lajord Munk; Thomas Nielsen; Thomas Rea Wittenborn; Johan Bussink; Jasper Lok; Hans Stødkilde-Jørgensen et al.
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Aarhus University
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Simulation of heterogeneous molecular delivery in tumours using μCT reconstructions and MRI validation

Microvascular Research
2016-11-01 | Journal article | Author
DOI: 10.1016/j.mvr.2016.08.004
SOURCE-WORK-ID:

9e277953-7976-49ac-94a2-cc4ae50a5182

PMID: 27569845
EID:

2-s2.0-84983543815
Contributors: Thomas Rea Wittenborn; Thomas Nielsen; Jesper Skovhus Thomsen; Michael Robert Horsman; Jens Vinge Nygaard
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Aarhus University
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Targeting tumour hypoxia to improve outcome of stereotactic radiotherapy

Acta Oncologica
2015 | Journal article | Author
DOI: 10.3109/0284186X.2015.1064162
SOURCE-WORK-ID:

4d8527fb-ca01-4641-90d1-42b9eb66295f

PMID: 26329662
EID:

2-s2.0-84940688399
Contributors: Thomas Rea Wittenborn; Michael R Horsman
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Aarhus University
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Synthesis and biochemical evaluation of benzoylbenzophenone thiosemicarbazone analogues as potent and selective inhibitors of cathepsin L

Bioorganic & Medicinal Chemistry
2015-11-01 | Journal article | Author
DOI: 10.1016/j.bmc.2015.09.036
SOURCE-WORK-ID:

bd84642f-8ae6-46f5-a935-ae2fd0330f2f

PMID: 26462052
EID:

2-s2.0-84946148009
Contributors: Erica N Parker; Jiangli Song; G D Kishore Kumar; Samuel O Odutola; Gustavo E Chavarria; Amanda K Charlton-Sevcik; Tracy E Strecker; Ashleigh L Barnes; Dhivya R Sudhan; Thomas Rea Wittenborn et al.
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Aarhus University
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A combretastatin-mediated decrease in neutrophil concentration in peripheral blood and the impact on the anti-tumor activity of this drug in two different murine tumor models

PLOS ONE
2014 | Journal article | Author
DOI: 10.1371/journal.pone.0110091
SOURCE-WORK-ID:

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PMID: 25299269
EID:

2-s2.0-84907856513
Contributors: Anja Bille Bohn; Thomas Rea Wittenborn; Anne Sofie Brems-Eskildsen; Tinne Laurberg; Lotte Bonde Bertelsen; Thomas Nielsen; Hans Stødkilde-Jørgensen; Bjarne Kuno Møller; Michael R Horsman
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Aarhus University
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Accumulation of nano-sized particles in a murine model of angiogenesis

Biochemical and Biophysical Research Communications
2014-01-10 | Journal article | Author
DOI: 10.1016/j.bbrc.2013.11.127
SOURCE-WORK-ID:

96b15ebe-21c7-43e9-9d5a-d4f6bd7ea3c1

PMID: 24321551
EID:

2-s2.0-84892433780
Contributors: Thomas Rea Wittenborn; Esben K U Larsen; Thomas Nielsen; Louise M Rydtoft; Line Hansen; Jens Vinge Nygaard; Thomas Vorup-Jensen; Jorgen Kjems; Michael R Horsman; Niels Chr. Nielsen
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Aarhus University
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Ultra-High-Field DCE-MRI of Angiogenesis in a Novel Angiogenesis Mouse Model

Journal of Magnetic Resonance Imaging
2012 | Journal article | Author
DOI: 10.1002/jmri.22855
SOURCE-WORK-ID:

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EID:

2-s2.0-84857084370

PMID: 22031493
Contributors: Thomas Rea Wittenborn; Thomas Nielsen; Jens Vinge Nygaard; Esben Kjær Unmack Larsen; Troels Thim; Louise Munk Rydtoft; Thomas Vorup-Jensen; Jorgen Kjems; Niels Chr. Nielsen; Michael Robert Horsman et al.
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Aarhus University
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Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) in preclinical studies of antivascular treatments

Pharmaceutics
2012-12-01 | Journal article | Author
DOI: 10.3390/pharmaceutics4040563
SOURCE-WORK-ID:

046c51e5-dc63-461c-a3fb-db3e1b572c1b

EID:

2-s2.0-84871547926

PMID: 24300371
Contributors: Thomas Nielsen; Thomas Rea Wittenborn; M.R. Horsman
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Aarhus University
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Accumulation of magnetic iron oxide nanoparticles coated with variably sized polyethylene glycol in murine tumors

Nanoscale
2012-03-06 | Journal article | Author
DOI: 10.1039/C2NR11554A
SOURCE-WORK-ID:

3bc02ec5-4a6f-408d-bd61-49af6c40092f

EID:

2-s2.0-84861852448
Contributors: Esben Kjær Unmack Larsen; Thomas Nielsen; Thomas Rea Wittenborn; Louise Munk Rydtoft; Arcot R. Lokanathan; Line Hansen; Leif Østergaard; Peter Kingshott; Kenneth A Howard; Flemming Besenbacher et al.
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Aarhus University
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Imaging angiogenesis: a novel angiogenesis model for testing functionalized nano-sized iron oxide particles

2011 | Dissertation or Thesis | Author
SOURCE-WORK-ID:

7f165153-2ccb-4184-a7a1-1cc4a389a35d
Contributors: Thomas Rea Wittenborn
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Aarhus University

A novel angiogenesis mouse model for screening functionalized nano-particles

Ph.d-dag , Aarhus, Denmark, 15/01/2010
2010 | Conference abstract | Author
SOURCE-WORK-ID:

614a624e-6583-4b55-9eb6-00737cbc425c
Contributors: Thomas Rea Wittenborn; Jens Vinge Nygaard; E. K. U. Larsen; T. Nielsen; Troels Thim; Michael Robert Horsman; Thomas Vorup-Jensen; Jørgen Kjems; Erling Falk
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Aarhus University

Characteristics and biological variations of M-ficolin, a pattern recognition molecule, in plasma

Journal of Innate Immunity
2010 | Journal article | Author
DOI: 10.1159/000218324
SOURCE-WORK-ID:

1fb6abac-7a7b-41dd-968c-3d921641f150

PMID: 20375634
EID:

2-s2.0-77953402526
Contributors: Thomas Rea Wittenborn; Steffen Thiel; Lisbeth Jensen; Hans J Nielsen; Jens Christian Jensenius
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Aarhus University
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A Novel in Vivo Angiogenesis Mouse Model

Arteriosclerosis, Thrombosis, and Vascular Biology
2009 | Journal article | Author
SOURCE-WORK-ID:

f48dada0-2209-11df-b95d-000ea68e967b
Contributors: Thomas Rea Wittenborn; Jens Vinge Nygaard; Michael Robert Horsman; Thomas Vorup-Jensen; Jorgen Kjems; Troels Thim; Thomas Nielsen; Esben Kjær Unmack Larsen; Erling Falk
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Aarhus University

Characteristics and biological variations of M-ficolin, a pattern recognition molecule

Journal of Innate Immunity
2009 | Journal article | Author
SOURCE-WORK-ID:

b10f8d90-0b2b-11df-b95d-000ea68e967b
Contributors: Thomas Rea Wittenborn; Steffen Thiel; Lisbeth Jensen; HJ Nielsen; Jens Christian Jensenius
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Aarhus University

Size-Dependent Accumulation of PEGylated Silane-Coated Magnetic Iron Oxide Nanoparticles in Murine Tumors

A C S Nano
2009 | Journal article | Author
DOI: 10.1021/nn900330m
SOURCE-WORK-ID:

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PMID: 19572620
EID:

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Contributors: Esben Kjær Unmack Larsen; Thomas Nielsen; Thomas Rea Wittenborn; Henrik Birkedal; Thomas Vorup-Jensen; Mogens H Jakobsen; Leif Østergaard; Michael R Horsman; Flemming Besenbacher; Kenneth A Howard et al.
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Aarhus University
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