Personal information

Websites & social links

Watt Lab Website

Other IDs

Scopus Author ID: 7103386098
Loop profile: 50412
SciProfiles: 2413979

Activities

Collapse all

Employment (1)

McGill University: Montreal, QC, CA

2011-09-01 to present | Associate Professor (Biology)
Employment
Source: Self-asserted source
Alanna Watt

Education and qualifications (1)

Brandeis University: Waltham, MA, US

1997 to 2003 | PhD (Biology)
Education
Source: Self-asserted source
Alanna Watt

Works (37)

Laser microsurgery for presynaptic interrogation

Nature Protocols
2025-02-07 | Journal article
DOI: 10.1038/s41596-024-01125-5
Contributors: Hovy Ho-Wai Wong; Alanna J. Watt; P. Jesper Sjöström
Source: check_circle
Crossref

Human-specific features of cerebellar astrocytes and Purkinje cells: an anatomical comparison with mice and macaques

2024-08-13 | Preprint
DOI: 10.1101/2024.08.13.607849
Contributors: Christa Hercher; Kristin Ellerbeck; Louise Toutée; Xinyu Ye; Refilwe Mpai; Maria Antonietta Davoli; Alanna J. Watt; Keith K. Murai; Gustavo Turecki; Naguib Mechawar
Source: check_circle
Crossref

Structured connectivity in the output of the cerebellar cortex

Nature Communications
2024-07-09 | Journal article
DOI: 10.1038/s41467-024-49339-1
Contributors: Kim M. Gruver; Jenny W. Y. Jiao; Eviatar Fields; Sen Song; Per Jesper Sjöström; Alanna J. Watt
Source: check_circle
Crossref

Mitochondrial damage and impaired mitophagy contribute to disease progression in SCA6

Acta Neuropathologica
2024-06 | Journal article
DOI: 10.1007/s00401-023-02680-z
Contributors: Tsz Chui Sophia Leung; Eviatar Fields; Namrata Rana; Ru Yi Louisa Shen; Alexandra E. Bernstein; Anna A. Cook; Daniel E. Phillips; Alanna J. Watt
Source: check_circle
Crossref

Endosomal dysfunction contributes to cerebellar deficits in spinocerebellar ataxia type 6

eLife
2023-12-12 | Journal article
DOI: 10.7554/eLife.90510.3
Contributors: Anna A Cook; Tsz Chui Sophia Leung; Max Rice; Maya Nachman; Élyse Zadigue-Dube; Alanna Jean Watt
Source: check_circle
Crossref

Endosomal dysfunction contributes to cerebellar deficits in spinocerebellar ataxia type 6

eLife
2023-12-12 | Journal article
DOI: 10.7554/eLife.90510
Contributors: Anna A Cook; Tsz Chui Sophia Leung; Max Rice; Maya Nachman; Élyse Zadigue-Dube; Alanna Jean Watt
Source: check_circle
Crossref

Endosomal dysfunction contributes to cerebellar deficits in spinocerebellar ataxia type 6

2023-11-09 | Preprint
DOI: 10.7554/eLife.90510.2
Contributors: Anna A. Cook; Tsz Chui Sophia Leung; Max Rice; Maya Nachman; Élyse Zadigue-Dubé; Alanna J. Watt
Source: check_circle
Crossref

Endosomal dysfunction contributes to cerebellar deficits in spinocerebellar ataxia type 6

2023-08-18 | Preprint
DOI: 10.7554/eLife.90510.1
Contributors: Anna A. Cook; Tsz Chui Sophia Leung; Max Rice; Maya Nachman; Élyse Zadigue-Dubé; Alanna J. Watt
Source: check_circle
Crossref

A mitochondrial-targeted antioxidant (MitoQ) improves motor coordination and reduces Purkinje cell death in a mouse model of ARSACS

Neurobiology of Disease
2023-07 | Journal article
DOI: 10.1016/j.nbd.2023.106157
Part of ISSN: 0969-9961
Contributors: Brenda Toscano Márquez; Tsz Chui Sophia Leung; Jeanette Hui; François Charron; R. Anne McKinney; Alanna J. Watt
Source: Self-asserted source
Alanna Watt

Comparing mouse and human brains

eLife
2023-07-10 | Journal article
DOI: 10.7554/eLife.90017
Contributors: Hovy Ho-Wai Wong; Christina You Chien Chou; Alanna Jean Watt; Per Jesper Sjöström
Source: check_circle
Crossref

Endosomal dysfunction contributes to cerebellar deficits in spinocerebellar ataxia type 6

2023-06-26 | Preprint
DOI: 10.1101/2023.06.26.546542
Contributors: Anna A. Cook; Tsz Chui Sophia Leung; Max Rice; Maya Nachman; Élyse Zadigue-Dubé; Alanna J. Watt
Source: check_circle
Crossref

Structured connectivity in the output of the cerebellar cortex

2023-03-18 | Preprint
DOI: 10.1101/2023.03.17.533173
Contributors: Kim M. Gruver; Jenny W. Y. Jiao; Eviatar Fields; Sen Song; Per Jesper Sjöström; Alanna J. Watt
Source: check_circle
Crossref

Activation of TrkB-Akt signaling rescues deficits in a mouse model of SCA6

Science Advances
2022-09-16 | Journal article
DOI: 10.1126/sciadv.abh3260
Contributors: Anna A. Cook; Sriram Jayabal; Jacky Sheng; Eviatar Fields; Tsz Chui Sophia Leung; Sabrina Quilez; Eileen McNicholas; Lois Lau; Shixia Huang; Alanna J. Watt
Source: check_circle
Crossref

Loss of Flocculus Purkinje Cell Firing Precision Leads to Impaired Gaze Stabilization in a Mouse Model of Spinocerebellar Ataxia Type 6 (SCA6)

Cells
2022-09-02 | Journal article
DOI: 10.3390/cells11172739
Contributors: Hui Ho Vanessa Chang; Anna A. Cook; Alanna J. Watt; Kathleen E. Cullen
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Local axonal translation sustains synapse-type-specific neurotransmission

2022-06-30 | Preprint
DOI: 10.1101/2022.06.27.497827
Contributors: Hovy Ho-Wai Wong; Alanna J. Watt; P. Jesper Sjöström
Source: check_circle
Crossref

Restoration of BDNF-TrkB signaling rescues deficits in a mouse model of SCA6

2021-02-22 | Preprint
DOI: 10.1101/2021.02.21.432180
Contributors: Anna A. Cook; Sriram Jayabal; Jacky Sheng; Eviatar Fields; Tsz Chui Sophia Leung; Sabrina Quilez; Eileen McNicholas; Lois Lau; Alanna J. Watt
Source: check_circle
Crossref

Sacs R272C missense homozygous mice develop an ataxia phenotype

Molecular brain
2019 | Journal article
DOI: 10.1186/s13041-019-0438-3
Source: Self-asserted source
Alanna Watt

Optimizing Optogenetic Activation of Purkinje Cell Axons to Investigate the Purkinje Cell – DCN Synapse

Frontiers in Synaptic Neuroscience
2019-11-22 | Journal article
DOI: 10.3389/fnsyn.2019.00031
Part of ISSN: 1663-3563
Source: Self-asserted source
Alanna Watt

The impact of light during the night

eLife
2019-11-12 | Journal article
DOI: 10.7554/eLife.52364
Contributors: Sophia TC Leung; R Anne McKinney; Alanna J Watt
Source: check_circle
Crossref

Altered synaptic and firing properties of cerebellar Purkinje cells in a mouse model of ARSACS

The Journal of physiology
2018 | Journal article
DOI: 10.1113/jp275902
Source: Self-asserted source
Alanna Watt

Transient cerebellar alterations during development prior to obvious motor phenotype in a mouse model of spinocerebellar ataxia type 6

The Journal of Physiology
2017-02 | Journal article
DOI: 10.1113/JP273184
Contributors: Sriram Jayabal; Lovisa Ljungberg; Alanna J. Watt
Source: check_circle
Crossref

New old drug(s) for spinocerebellar ataxias

The Journal of Physiology
2017-01 | Journal article
DOI: 10.1113/JP273149
Contributors: Visou Ady; Alanna J. Watt
Source: check_circle
Crossref

In Vitro Investigation of Synaptic Plasticity.

2016 | Journal article
DOI: 10.1101/pdb.top087262
PMID: 27250951
Contributors: Abrahamsson T; Lalanne T; Watt AJ; Sjöström PJ
Source: Self-asserted source
Alanna Watt via Europe PubMed Central

Long-Term Potentiation by Theta-Burst Stimulation Using Extracellular Field Potential Recordings in Acute Hippocampal Slices

2016 | Journal article
DOI: 10.1101/pdb.prot091298
Source: Self-asserted source
Alanna Watt

Transient Developmental Purkinje Cell Axonal Torpedoes in Healthy and Ataxic Mouse Cerebellum.

2016 | Journal article
PMID: 27853421
PMC: PMC5089982
Contributors: Ljungberg L; Lang-Ouellette D; Yang A; Jayabal S; Quilez S; Watt AJ
Source: Self-asserted source
Alanna Watt via Europe PubMed Central

4-aminopyridine reverses ataxia and cerebellar firing deficiency in a mouse model of spinocerebellar ataxia type 6.

2016-07 | Journal article
DOI: 10.1038/srep29489
PMID: 27381005
PMC: PMC4933933
Contributors: Jayabal S; Chang HH; Cullen KE; Watt AJ
Source: Self-asserted source
Alanna Watt via Europe PubMed Central

Rapid Onset of Motor Deficits in a Mouse Model of Spinocerebellar Ataxia Type 6 Precedes Late Cerebellar Degeneration

eneuro
2015-11 | Journal article
DOI: 10.1523/ENEURO.0094-15.2015
Contributors: Sriram Jayabal; Lovisa Ljungberg; Thomas Erwes; Alexander Cormier; Sabrina Quilez; Sara El Jaouhari; Alanna J. Watt
Source: check_circle
Crossref

Neuronal morphometry directly from bitmap images

Nature Methods
2014 | Journal article
DOI: 10.1038/nmeth.3125
EID:

2-s2.0-84921807601
Contributors: Ferreira, T.A.; Blackman, A.V.; Oyrer, J.; Jayabal, S.; Chung, A.J.; Watt, A.J.; Sjöström, P.J.; Van Meyel, D.J.
Source: Self-asserted source
Alanna Watt via Scopus - Elsevier

How to train a neuron

eLife
2013 | Journal article
DOI: 10.7554/eLife.00491
EID:

2-s2.0-84879036848
Contributors: Costa, R.P.; Watt, A.J.; Jesper Sjöström, P.
Source: Self-asserted source
Alanna Watt via Scopus - Elsevier

The metamorphosis of the developing cerebellar microcircuit

Current Opinion in Neurobiology
2011 | Journal article
DOI: 10.1016/j.conb.2011.01.009
EID:

2-s2.0-79955658128
Contributors: Van Welie, I.; Smith, I.T.; Watt, A.J.
Source: Self-asserted source
Alanna Watt via Scopus - Elsevier

Homeostatic plasticity and STDP: Keeping a neuron's cool in a fluctuating world

Frontiers in Synaptic Neuroscience
2010 | Journal article
DOI: 10.3389/fnsyn.2010.00005
EID:

2-s2.0-78649405204
Contributors: Watt, A.J.; Desai, N.S.
Source: Self-asserted source
Alanna Watt via Scopus - Elsevier

Traveling waves in developing cerebellar cortex mediated by asymmetrical Purkinje cell connectivity

Nature Neuroscience
2009 | Journal article
DOI: 10.1038/nn.2285
EID:

2-s2.0-63649158995
Contributors: Watt, A.J.; Cuntz, H.; Mori, M.; Nusser, Z.; Sjöström, P.J.; Häusser, M.
Source: Self-asserted source
Alanna Watt via Scopus - Elsevier

A proportional but slower NMDA potentiation follows AMPA potentiation in LTP

Nature Neuroscience
2004 | Journal article
DOI: 10.1038/nn1220
EID:

2-s2.0-11144353717
Contributors: Watt, A.J.; Sjöström, P.J.; Häusser, M.; Nelson, S.B.; Turrigiano, G.G.
Source: Self-asserted source
Alanna Watt via Scopus - Elsevier

Activity-dependent remodeling of presynaptic inputs by postsynaptic expression of activated CaMKII

Neuron
2003 | Journal article
DOI: 10.1016/S0896-6273(03)00422-7
EID:

2-s2.0-0042848901
Contributors: Pratt, K.G.; Watt, A.J.; Griffith, L.C.; Nelson, S.B.; Turrigiano, G.G.
Source: Self-asserted source
Alanna Watt via Scopus - Elsevier

Activity coregulates quantal AMPA and NMDA currents at neocortical synapses

Neuron
2000 | Journal article
EID:

2-s2.0-0033695958
Contributors: Watt, A.J.; Van Rossum, M.C.W.; MacLeod, K.M.; Nelson, S.B.; Turrigiano, G.G.
Source: Self-asserted source
Alanna Watt via Scopus - Elsevier

Cooperation of Sp1 and p300 in the induction of the CDK inhibitor p21(WAF1/CIP1) during NGF-mediated neuronal differentiation

Oncogene
1999 | Journal article
DOI: 10.1038/sj.onc.1202712
EID:

2-s2.0-0033529096
Contributors: Billon, N.; Carlisi, D.; Datto, M.B.; Van Grunsven, L.A.; Watt, A.; Wang, X.-F.; Rudkin, B.B.
Source: Self-asserted source
Alanna Watt via Scopus - Elsevier

In Vitro Investigation of Synaptic Plasticity

Cold Spring Harb Protoc
Journal article
DOI:

pdb.top087262
Source: Self-asserted source
Alanna Watt

Peer review (9 reviews for 4 publications/grants)

Review activity for Cell reports. (1)
Review activity for eLife (1)
Review activity for Nature communications (6)
Review activity for Neurobiology of disease. (1)
How many people are using ORCID?