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Other IDs

Scopus Author ID: 8099358400

Keywords

Clinical Pharmacology, PKPD, Modeling, Biopharmaceutics, Clinical Development, Gene & Cell Therapy,

Countries

Canada

Activities

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Employment (6)

AstraZeneca (Canada): Mississauga, CA

2024 to present | Director (Clinical Pharmacology and Safety Sciences)
Employment
Source: Self-asserted source
Noha Rayad

Parexel International Corporation: Waltham, MA, US

2020 to 2024 | Director (Clinical Pharmacology, Modeling and Simulation)
Employment
Source: Self-asserted source
Noha Rayad

BioPharma Services Inc.: Toronto, ON, CA

2016 to 2020 | Manager, Pharmacokinetics (Clinical Pharmacology)
Employment
Source: Self-asserted source
Noha Rayad

Apotex Inc: Toronto, ON, CA

2015 to 2016 | Pharmacokinetic Scientist (Research & Development, BioClinical Development)
Employment
Source: Self-asserted source
Noha Rayad

University Health Network: Toronto, ON, CA

2015 | Research Scientist (Faculty of Pharmacy)
Employment
Source: Self-asserted source
Noha Rayad

Ain Shams University: Cairo, EG

2014 | Associate Professor (Faculty of Pharmacy)
Employment
Source: Self-asserted source
Noha Rayad

Education and qualifications (6)

University at Buffalo - The State University of New York: Buffalo, NY, US

2019 | PK/PD modeling (Pharmacometrics)
Qualification
Source: Self-asserted source
Noha Rayad

Uppsala University: Uppsala, SE

2011 | Scientist (Pharmaceutical Bioinformatics)
Education
Source: Self-asserted source
Noha Rayad

The University of Manchester: Manchester, Greater Manchester, GB

2008 | Postdoc Fellow (Nanotechnology for Gene therapy)
Education
Source: Self-asserted source
Noha Rayad

Uppsala University: Uppsala, Uppsala, SE

2007 | PhD (Biopharmaceutics & Pharmacokinetics)
Education
Source: Self-asserted source
Noha Rayad

Ain Shams University Faculty of Pharmacy: Cairo, EG

2002 | MSc (Biopharmaceutics & Pharmacokinetics)
Education
Source: Self-asserted source
Noha Rayad

Cairo University: Cairo, EG

1995 | Bachelor of Pharmacy (Faculty of Pharmacy)
Education
Source: Self-asserted source
Noha Rayad

Professional activities (6)

University of Toronto: Toronto, ON, CA

Invited Lecturer (Faculty of Pharmacy)
Invited position
Source: Self-asserted source
Noha Rayad

Misr El Kheir Foundation: Cairo, EG

Distinct Publication Award
Distinction
Source: Self-asserted source
Noha Rayad

Dr Walid Kayali Prize: Riyadh, SA

Dr Walid Kayali Prize for Best Scientific Research Article
Distinction
Source: Self-asserted source
Noha Rayad

Arab Co for Drug Industries and Medical Appliances: Amman, JO

ACDIMA Scientific Research Award (Best Article)
Distinction
Source: Self-asserted source
Noha Rayad

American Association of Pharmaceutical Scientists: Arlington, VA, US

Membership
Source: Self-asserted source
Noha Rayad

Ain Shams University: Cairo, EG

Internationally-Recognized Publication Award
Distinction
Source: Self-asserted source
Noha Rayad

Works (39)

Getting the Dose Right in Drug Development for Rare Diseases: Barriers and Enablers

Clinical Pharmacology & Therapeutics
2024-12 | Journal article
DOI: 10.1002/cpt.3407
Contributors: Mariam A. Ahmed; Rajesh Krishna; Noha Rayad; Salwa Albusaysi; Amitava Mitra; Elizabeth Shang; Yuen Yi Hon; Bilal AbuAsal; Rana Bakhaidar; Youssef M. Roman et al.
Source: check_circle
Crossref

New Horizons of Model Informed Drug Development in Rare Diseases Drug Development

Clinical Pharmacology & Therapeutics
2024-12 | Journal article
DOI: 10.1002/cpt.3366
Contributors: Amitava Mitra; Nessy Tania; Mariam A. Ahmed; Noha Rayad; Rajesh Krishna; Salwa Albusaysi; Rana Bakhaidar; Elizabeth Shang; Maria Burian; Michelle Martin‐Pozo et al.
Source: check_circle
Crossref

Pharmacokinetics of zoliflodacin in healthy participants in the presence of itraconazole suggest no clinically meaningful CYP3A4-mediated drug-drug interactions

34th ECCMID 2024 - European Congress of Clinical Microbiology and Infectious Diseases (
2024-06 | Conference poster
Contributors: Noha Rayad
Source: Self-asserted source
Noha Rayad

Unveiling pH-dependent drug-drug interactions in anticancer protein kinase inhibitors: a review of recent FDA and EMA regulatory submissions

16th EACPT 2024 - European Association for Clinical Pharmacology and Therapeutics
2024-06-01 | Conference poster
Contributors: Noha Rayad
Source: Self-asserted source
Noha Rayad

A bioequivalence and food effect clinical study of zoliflodacin, first-in-class oral antibiotic, being developed for the treatment of uncomplicated gonorrhea.

ASCPT Annual Meeting, Colorado Springs, March 2024
2024-03-27 | Conference poster
Contributors: Noha Rayad
Source: Self-asserted source
Noha Rayad

Model-Informed Approaches and Innovative Clinical Trial Design for Adeno-Associated Viral Vector-Based Gene Therapy Product Development: A White Paper

Clinical Pharmacology & Therapeutics
2023-06-14 | Journal article
Contributors: Noha Rayad
Source: Self-asserted source
Noha Rayad

Can PK/PD Modeling and Simulation Bring a Gene Therapy (for β-thalassemia) to Patients-in-need Faster?

ASGCPT 26th Annual Meeting, May 16-20, 2023 | Los Angeles, CA at
2023-05-16 | Conference poster
Contributors: Noha Rayad
Source: Self-asserted source
Noha Rayad

Pilot Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Abuse Liability of an Abuse-Deterrent Immediate-Release Formulation (ADAIR)

U.S. National Library of Medicine
2020 | Interactive resource
Source: Self-asserted source
Noha Rayad

Antiviral treatment for treatment-naïve chronic hepatitis B: Systematic review and network meta-analysis of randomized controlled trials

Systematic Reviews
2019 | Journal article
DOI: 10.1186/s13643-019-1126-1
EID:

2-s2.0-85071007683
Contributors: Wong, W.W.L.; Pechivanoglou, P.; Wong, J.; Bielecki, J.M.; Haines, A.; Erman, A.; Saeed, Y.; Phoon, A.; Tadrous, M.; Younis, M. et al.
Source: Self-asserted source
Noha Rayad via Scopus - Elsevier

Drug Interaction With Proton Pump Inhibitors for Nifedipine ER Tablets

U.S. National Library of Medicine
2019-08-01 | Interactive resource
Source: Self-asserted source
Noha Rayad

Strategies for oral delivery and mitochondrial targeting of CoQ10

Drug Delivery
2016 | Journal article
DOI: 10.3109/10717544.2014.993747
EID:

2-s2.0-84975144914
Contributors: Zaki, N.M.
Source: Self-asserted source
Noha Rayad via Scopus - Elsevier

Smart Liposomal Chitosan–based Autogel for Intrapocket Delivery of Ofloxacin in the Treatment of Aggressive Periodontitis in Human Volunteers

Canadian Society for Pharmaceutical Sciences (CSPS) and CRS (Controlled Release Society;Canadian Chapter)
2015 | Conference poster
Source: Self-asserted source
Noha Rayad

Augmented cytotoxicity of hydroxycamptothecin-loaded nanoparticles in lung and colon cancer cells by chemosensitizing pharmaceutical excipients

Drug Delivery
2014 | Journal article
DOI: 10.3109/10717544.2013.838808
EID:

2-s2.0-84901916474
Contributors: Zaki, N.M.
Source: Self-asserted source
Noha Rayad via Scopus - Elsevier

Bioavailability enhancement of verapamil HCl via intranasal chitosan microspheres

European Journal of Pharmaceutical Sciences
2014 | Journal article
DOI: 10.1016/j.ejps.2013.08.029
EID:

2-s2.0-84884934776
Contributors: Abdel Mouez, M.; Zaki, N.M.; Mansour, S.; Geneidi, A.S.
Source: Self-asserted source
Noha Rayad via Scopus - Elsevier

Impact of microparticle formulation approaches on drug burst release: A level A IVIVC

Journal of Microencapsulation
2014 | Journal article
DOI: 10.3109/02652048.2014.913724
EID:

2-s2.0-84911492546
Contributors: Ishak, R.A.H.; Mortada, N.D.; Zaki, N.M.; El-Shamy, A.E.-H.A.; Awad, G.A.S.
Source: Self-asserted source
Noha Rayad via Scopus - Elsevier

Pharmacists' and physicians' perception and exposure to drug promotion: A Saudi study

Saudi Pharmaceutical Journal
2014 | Journal article
DOI: 10.1016/j.jsps.2014.02.008
EID:

2-s2.0-84920683488
Contributors: Zaki, N.M.
Source: Self-asserted source
Noha Rayad via Scopus - Elsevier

Progress and problems in nutraceuticals delivery

Journal of Bioequivalence and Bioavailability
2014 | Journal article
DOI: 10.4172/jbb.1000183
EID:

2-s2.0-84904022460
Contributors: Zaki, N.M.
Source: Self-asserted source
Noha Rayad via Scopus - Elsevier

Use, attitudes and knowledge of medications among pregnant women: A Saudi study

Saudi Pharmaceutical Journal
2014 | Journal article
DOI: 10.1016/j.jsps.2013.09.001
EID:

2-s2.0-84920195153
Contributors: Zaki, N.M.; Albarraq, A.A.
Source: Self-asserted source
Noha Rayad via Scopus - Elsevier

A comparative study of chitosan shielding effect on nano-carriers hydrophilicity and biodistribution

Carbohydrate Polymers
2013 | Journal article
DOI: 10.1016/j.carbpol.2013.01.072
EID:

2-s2.0-84874398425
Contributors: Ishak, R.A.H.; Awad, G.A.S.; Zaki, N.M.; El-Shamy, A.E.-H.A.; Mortada, N.D.
Source: Self-asserted source
Noha Rayad via Scopus - Elsevier

Cytotoxicity of pharmaceutically optimized nanometric systems of a chemotherapeutic drug on breast and liver tumor cells

International Journal of Pharmacy and Pharmaceutical Sciences
2013 | Journal article
EID:

2-s2.0-84878383776
Contributors: Zaki, N.M.; Albarraq, A.; Hafez, M.M.
Source: Self-asserted source
Noha Rayad via Scopus - Elsevier

Toward an Alternative Therapeutic Approach for Skin Infections: Antagonistic Activity of Lactobacilli Against Antibiotic-Resistant Staphylococcus aureus and Pseudomonas aeruginosa

Probiotics and Antimicrobial Proteins
2013 | Journal article
DOI: 10.1007/s12602-013-9137-z
EID:

2-s2.0-84879782910
Contributors: Hafez, M.M.; Maghrabi, I.A.; Zaki, N.M.
Source: Self-asserted source
Noha Rayad via Scopus - Elsevier

Trends in therapeutic interventions in patients with diabetes mellitus in Saudi Arabia

International Journal of Pharmacy and Pharmaceutical Sciences
2013 | Journal article
EID:

2-s2.0-84882738744
Contributors: Zaki, N.M.; Maghrabi, I.
Source: Self-asserted source
Noha Rayad via Scopus - Elsevier

CNS delivery of drugs: Challenges and chances

Journal of Bioequivalence and Bioavailability
2012 | Journal article
DOI: 10.4172/jbb.10000e20
EID:

2-s2.0-84866328908
Contributors: Zaki, N.M.
Source: Self-asserted source
Noha Rayad via Scopus - Elsevier

Enhanced antibacterial effect of ceftriaxone sodium-loaded chitosan nanoparticles against intracellular Salmonella typhimurium

AAPS PharmSciTech
2012 | Journal article
DOI: 10.1208/s12249-012-9758-7
EID:

2-s2.0-84862855871
Contributors: Zaki, N.M.; Hafez, M.M.
Source: Self-asserted source
Noha Rayad via Scopus - Elsevier

PEGylation of nanosubstrates (Titania) with multifunctional reagents: At the crossroads between nanoparticles and nanocomposites

Langmuir
2012 | Journal article
DOI: 10.1021/la3012958
EID:

2-s2.0-84864701310
Contributors: Kotsokechagia, T.; Zaki, N.M.; Syres, K.; Leonardis, P.D.; Thomas, A.; Cellesi, F.; Tirelli, N.
Source: Self-asserted source
Noha Rayad via Scopus - Elsevier

Site-specific delivery of the nutraceutical CoQ10 for periodontal therapy

International Journal of Pharmacy and Pharmaceutical Sciences
2012 | Journal article
EID:

2-s2.0-84859993140
Contributors: Zaki, N.M.
Source: Self-asserted source
Noha Rayad via Scopus - Elsevier

Assessment of nanomaterials cytotoxicity and internalization.

Methods in molecular biology (Clifton, N.J.)
2011 | Journal article
EID:

2-s2.0-79952202001
Contributors: Zaki, N.M.; Tirelli, N.
Source: Self-asserted source
Noha Rayad via Scopus - Elsevier

Chitosan and chitosan derivatives: A spotlight on cellular interactions

Handbook of Chitosan Research and Applications
2011 | Book chapter
EID:

2-s2.0-84896228052
Contributors: Zaki, N.M.
Source: Self-asserted source
Noha Rayad via Scopus - Elsevier

Hybrid bionanomaterials based on nanocrystalline TiO<inf>2</inf>and catechol-grafted polymers: The effect of composition and morphology on photo and bioactivity

Technical Proceedings of the 2011 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2011
2011 | Conference paper
EID:

2-s2.0-81455143891
Contributors: Cadman, C.; Ragupathy, L.; Zaki, N.M.; Tirelli, N.; Cellesi, F.
Source: Self-asserted source
Noha Rayad via Scopus - Elsevier

Laboratory-based prediction of drug biopharmaceutical properties

Journal of Bioequivalence and Bioavailability
2011 | Journal article
DOI: 10.4172/jbb.10000e10
EID:

2-s2.0-84857015142
Contributors: Zaki Rayad, N.M.
Source: Self-asserted source
Noha Rayad via Scopus - Elsevier

Nanocarriers for cytoplasmic delivery: Cellular uptake and intracellular fate of chitosan and hyaluronic acid-coated chitosan nanoparticles in a phagocytic cell model

Macromolecular Bioscience
2011 | Journal article
DOI: 10.1002/mabi.201100156
EID:

2-s2.0-81355154809
Contributors: Zaki, N.M.; Nasti, A.; Tirelli, N.
Source: Self-asserted source
Noha Rayad via Scopus - Elsevier

Structural features determining the intestinal epithelial permeability and efflux of novel HIV-1 protease inhibitors

Journal of Pharmaceutical Sciences
2011 | Journal article
DOI: 10.1002/jps.22570
EID:

2-s2.0-79960156077
Contributors: Lazorova, L.; Hubatsch, I.; Ekegren, J.K.; Gising, J.; Nakai, D.; Zaki, N.M.; Bergström, C.A.S.; Norinder, U.; Larhed, M.; Artursson, P.
Source: Self-asserted source
Noha Rayad via Scopus - Elsevier

A modified physiological BCS for prediction of intestinal absorption in drug discovery

Molecular Pharmaceutics
2010 | Journal article
DOI: 10.1021/mp100124f
EID:

2-s2.0-77957738213
Contributors: Zaki, N.M.; Artursson, P.; Bergström, C.A.S.
Source: Self-asserted source
Noha Rayad via Scopus - Elsevier

Gateways for the intracellular access of nanocarriers: A review of receptor-mediated endocytosis mechanisms and of strategies in receptor targeting

Expert Opinion on Drug Delivery
2010 | Journal article
DOI: 10.1517/17425247.2010.501792
EID:

2-s2.0-77954880957
Contributors: Zaki, N.M.; Tirelli, N.
Source: Self-asserted source
Noha Rayad via Scopus - Elsevier

Chitosan/TPP and chitosan/TPP-hyaluronic acid nanoparticles: Systematic optimisation of the preparative process and preliminary biological evaluation

Pharmaceutical Research
2009 | Journal article
DOI: 10.1007/s11095-009-9908-0
EID:

2-s2.0-67650065139
Contributors: Nasti, A.; Zaki, N.M.; De Leonardis, P.; Ungphaiboon, S.; Sansongsak, P.; Rimoli, M.G.; Tirelli, N.
Source: Self-asserted source
Noha Rayad via Scopus - Elsevier

Enhanced bioavailability of metoclopramide HCl by intranasal administration of a mucoadhesive in situ gel with modulated rheological and mucociliary transport properties

European Journal of Pharmaceutical Sciences
2007 | Journal article
DOI: 10.1016/j.ejps.2007.08.006
EID:

2-s2.0-35948992244
Contributors: Zaki, N.M.; Awad, G.A.; Mortada, N.D.; Abd ElHady, S.S.
Source: Self-asserted source
Noha Rayad via Scopus - Elsevier

Rapid-onset intranasal delivery of metoclopramide hydrochloride. Part I. Influence of formulation variables on drug absorption in anesthetized rats

International Journal of Pharmaceutics
2006 | Journal article
DOI: 10.1016/j.ijpharm.2006.07.040
EID:

2-s2.0-33751042889
Contributors: Zaki, N.M.; Awad, G.A.S.; Mortada, N.D.; Abd ElHady, S.S.
Source: Self-asserted source
Noha Rayad via Scopus - Elsevier

Rapid-onset intranasal delivery of metoclopramide hydrochloride. Part II: Safety of various absorption enhancers and pharmacokinetic evaluation

International Journal of Pharmaceutics
2006 | Journal article
DOI: 10.1016/j.ijpharm.2006.07.038
EID:

2-s2.0-33751030524
Contributors: Zaki, N.M.; Mortada, N.D.; Awad, G.A.S.; ElHady, S.S.A.
Source: Self-asserted source
Noha Rayad via Scopus - Elsevier

Development of in situ gelling and mucoadhesive mebeverine hydrochloride solution for rectal administration

Saudi Pharmaceutical Journal
2003 | Journal article
EID:

2-s2.0-0346458604
Contributors: Abd ElHady, S.S.; Mortada, N.D.; Awad, G.A.S.; Zaki, N.M.; Taha, R.A.
Source: Self-asserted source
Noha Rayad via Scopus - Elsevier
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