Personal information

stem cells, diabetes, epigenetic, long noncoding RNA, endoderm, histone modification, transcriptional regulation, cell differentiation
China

Activities

Employment (3)

Zhongnan Hospital & Medical Research Institute, School of Medicine, Wuhan University: Wuhan, CN

2015-07-01 to present | PI
Employment
Source: Self-asserted source
Wei Jiang

Howard Hughes Medical Institue - Harvard Medical School, Boston Children's Hospital: Boston, MA, US

2012-07-01 to 2015-06 | Research Fellow
Employment
Source: Self-asserted source
Wei Jiang

Howard Hughes Medical Institute - University of North Carolina at Chapel Hill: Chapel Hill, NC, US

2011-01 to 2012-06-30 | Postdoctoral Research Associate (Lineberger Comprehensive Cancer Center)
Employment
Source: Self-asserted source
Wei Jiang

Education and qualifications (2)

Peking University: Beijing, Beijing, CN

2005-09 to 2010-07 | Ph.D. (Department of Cell Biology and Genetics)
Education
Source: Self-asserted source
Wei Jiang

Peking University: Beijing, Beijing, CN

2001-09 to 2005-07 | BS. (College of Life Sciences)
Education
Source: Self-asserted source
Wei Jiang

Funding (1)

Epigenetic regulation to generate human ES cell-derived beta cells

2012-07 to 2015-06 | Grant
Juvenile Diabetes Research Foundation International (NY, NY, US)
GRANT_NUMBER:

3-2012-293

Source: Self-asserted source
Wei Jiang

Works (36)

Protocol for differentiating cardiomyocytes and generating engineered heart tissues from human feeder-free extended pluripotent stem cells

STAR Protocols
2025-03 | Journal article
Contributors: Zhongjun Wan; Shanshan Wen; Ran Zheng; Li Li; Wei Jiang; Donghui Zhang
Source: check_circle
Crossref

Prostatic lineage differentiation from human embryonic stem cells through inducible expression of NKX3-1

Stem Cell Research & Therapy
2024-09-02 | Journal article
Contributors: Songwei Wang; Yangyang Yu; Yinglei Li; Tianzhe Zhang; Wei Jiang; Xinghuan Wang; Ran Liu
Source: check_circle
Crossref

Cell size regulates human endoderm specification through actomyosin-dependent AMOT-YAP signaling

Stem Cell Reports
2024-08 | Journal article
Contributors: Lai Jiang; Chenchao Yan; Ying Yi; Lihang Zhu; Zheng Liu; Donghui Zhang; Wei Jiang
Source: check_circle
Crossref

H3K27me3-mediated epigenetic regulation in pluripotency maintenance and lineage differentiation

Cell Insight
2024-08 | Journal article
Contributors: Liwen Jiang; Linfeng Huang; Wei Jiang
Source: check_circle
Crossref

Fatty acid synthesis and oxidation regulate human endoderm differentiation by mediating SMAD3 nuclear localization via acetylation

Developmental Cell
2023-09 | Journal article
Contributors: Ying Yi; Xianchun Lan; Yinglei Li; Chenchao Yan; Jing Lv; Tianzhe Zhang; Wei Jiang
Source: check_circle
Crossref

A desert lncRNA HIDEN regulates human endoderm differentiation via interacting with IMP1 and stabilizing FZD5 mRNA

Genome Biology
2023-04-24 | Journal article
Contributors: Pei Lu; Jie Yang; Mao Li; Shanshan Wen; Tianzhe Zhang; Chenchao Yan; Ran Liu; Yu Xiao; Xinghuan Wang; Wei Jiang
Source: check_circle
Crossref

Translational landscape in human early neural fate determination

Development
2023-03-15 | Journal article
Contributors: Chenchao Yan; Yajing Meng; Jie Yang; Jian Chen; Wei Jiang
Source: check_circle
Crossref

Generation of high-performance human cardiomyocytes and engineered heart tissues from extended pluripotent stem cells

Cell Discovery
2022-10-11 | Journal article
Contributors: Li Li; Zhongjun Wan; Ruxiang Wang; Yuxin Zhao; Yida Ye; Pengcheng Yang; Yan Qi; Wei Jiang; Lin Cai; Donghui Zhang
Source: check_circle
Crossref

PCGF6 controls neuroectoderm specification of human pluripotent stem cells by activating SOX2 expression

Nature Communications
2022-08-06 | Journal article
Contributors: Xianchun Lan; Song Ding; Tianzhe Zhang; Ying Yi; Conghui Li; Wenwen Jin; Jian Chen; Kaiwei Liang; Hengbin Wang; Wei Jiang
Source: check_circle
Crossref

Stepwise differentiation of functional pancreatic β cells from human pluripotent stem cells

Cell Regeneration
2022-08-01 | Journal article
Contributors: Wenwen Jin; Wei Jiang
Source: check_circle
Crossref

Active endogenous retroviral elements in human pluripotent stem cells play a role in regulating host gene expression

Nucleic Acids Research
2022-05-20 | Journal article
Contributors: Tianzhe Zhang; Ran Zheng; Mao Li; Chenchao Yan; Xianchun Lan; Bei Tong; Pei Lu; Wei Jiang
Source: check_circle
Crossref

Mitochondrial dysfunction by TFAM depletion disrupts self-renewal and lineage differentiation of human PSCs by affecting cell proliferation and YAP response

Redox Biology
2022-04 | Journal article
Contributors: Yan Qi; Yida Ye; Ruxiang Wang; Senlin Yu; Yue Zhang; Jing Lv; Wenwen Jin; Shutao Xia; Wei Jiang; Yifei Li et al.
Source: check_circle
Crossref

Mitochondrial homeostasis regulates definitive endoderm differentiation of human pluripotent stem cells

Cell Death Discovery
2022-02-17 | Journal article
Contributors: Jing Lv; Ying Yi; Yan Qi; Chenchao Yan; Wenwen Jin; Liming Meng; Donghui Zhang; Wei Jiang
Source: check_circle
Crossref

CHD8 safeguards early neuroectoderm differentiation in human ESCs and protects from apoptosis during neurogenesis

Cell Death & Disease
2021-10-22 | Journal article
Contributors: Song Ding; Xianchun Lan; Yajing Meng; Chenchao Yan; Mao Li; Xiang Li; Jian Chen; Wei Jiang
Source: check_circle
Crossref

Derivation of feeder-free human extended pluripotent stem cells

Stem Cell Reports
2021-07 | Journal article
Contributors: Ran Zheng; Ting Geng; Dan-Ya Wu; Tianzhe Zhang; Hai-Nan He; Hai-Ning Du; Donghui Zhang; Yi-Liang Miao; Wei Jiang
Source: check_circle
Crossref

Lnc‐ing pluripotency maintenance and early differentiation in human pluripotent stem cells

The FASEB Journal
2021-04 | Journal article
Contributors: Pei Lu; Mao Li; Donghui Zhang; Wei Jiang
Source: check_circle
Crossref

Pluripotent stem cell differentiation as an emerging model to study human prostate development

Stem Cell Research & Therapy
2020-12 | Journal article
Contributors: Yangyang Yu; Wei Jiang
Source: check_circle
Crossref

Derivation of human extended pluripotent stem cells in feeder-free condition

2020-10-18 | Preprint
Contributors: Ran Zheng; Ting Geng; Dan-Ya Wu; Tianzhe Zhang; Hai-Nan He; Liyan Wang; Haining Du; Donghui Zhang; Yi-Liang Miao; Wei Jiang
Source: check_circle
Crossref

GATA6-AS1 Regulates GATA6 Expression to Modulate Human Endoderm Differentiation

Stem Cell Reports
2020-09 | Journal article
Contributors: Jie Yang; Pei Lu; Mao Li; Chenchao Yan; Tianzhe Zhang; Wei Jiang
Source: check_circle
Crossref

Dual Inhibition of BMP and WNT Signals Promotes Pancreatic Differentiation from Human Pluripotent Stem Cells

Stem Cells International
2019-12-01 | Journal article
Contributors: Mengtian Tan; Lai Jiang; Yinglei Li; Wei Jiang
Source: check_circle
Crossref

Epigenetic Regulation of Transition Among Different Pluripotent States: Concise Review

Stem Cells
2019-11-01 | Journal article
Contributors: Ting Geng; Donghui Zhang; Wei Jiang
Source: check_circle
Crossref

Histone Demethylase Expression Enhances Human Somatic Cell Nuclear Transfer Efficiency and Promotes Derivation of Pluripotent Stem Cells.

Cell stem cell
2015 | Journal article
WOSUID:

MEDLINE:26526725

Contributors: Chung, Young Gie; Matoba, Shogo; Liu, Yuting; Eum, Jin Hee; Lu, Falong; Jiang, Wei; Lee, Jeoung Eun; Sepilian, Vicken; Cha, Kwang Yul; Lee, Dong Ryul et al.
Source: Self-asserted source
Wei Jiang via ResearcherID

The lncRNA DEANR1 Facilitates Human Endoderm Differentiation by Activating FOXA2 Expression

Cell Reports
2015 | Journal article
WOSUID:

WOS:000352279800013

Contributors: Jiang, Wei; Liu, Yuting; Liu, Rui; Zhang, Kun; Zhang, Yi
Source: Self-asserted source
Wei Jiang via ResearcherID

Histone H3K27me3 demethylases KDM6A and KDM6B modulate definitive endoderm differentiation from human ESCs by regulating WNT signaling pathway

Cell Research
2013 | Journal article
WOSUID:

WOS:000313194700015

Contributors: Jiang, Wei; Wang, Jinzhao; Zhang, Yi
Source: Self-asserted source
Wei Jiang via ResearcherID

WNT3 Is a Biomarker Capable of Predicting the Definitive Endoderm Differentiation Potential of hESCs

Stem Cell Reports
2013 | Journal article
WOSUID:

WOS:000336632000007

Contributors: Jiang, Wei; Zhang, Donghui; Bursac, Nenad; Zhang, Yi
Source: Self-asserted source
Wei Jiang via ResearcherID

CD24: A Novel Surface Marker for PDX1-Positive Pancreatic Progenitors Derived from Human Embryonic Stem Cells

Stem Cells
2011 | Journal article
WOSUID:

WOS:000289157100008

Contributors: Jiang, Wei; Sui, Xin; Zhang, Donghui; Liu, Meng; Ding, Mingxiao; Shi, Yan; Deng, Hongkui
Source: Self-asserted source
Wei Jiang via ResearcherID

Derivation and characterization of Chinese human embryonic stem cell line with high potential to differentiate into pancreatic and hepatic cells

Chinese Medical Journal
2011 | Journal article
WOSUID:

WOS:000290289700018

Contributors: Shi Cheng; Shen Huan; Jiang Wei; Song Zhi-hua; Wang Cheng-yan; We Li-hui
Source: Self-asserted source
Wei Jiang via ResearcherID

Generation of pancreatic islet cells from human embryonic stem cells

Science in China Series C-Life Sciences
2009 | Journal article
WOSUID:

WOS:000268514900005

Contributors: Zhang DongHui; Jiang Wei; Shi Yan; Deng HongKui
Source: Self-asserted source
Wei Jiang via ResearcherID

Highly efficient differentiation of human ES cells and iPS cells into mature pancreatic insulin-producing cells

Cell Research
2009 | Journal article
WOSUID:

WOS:000265700100005

Contributors: Zhang, Donghui; Jiang, Wei; Liu, Meng; Sui, Xin; Yin, Xiaolei; Chen, Song; Shi, Yan; Deng, Hongkui
Source: Self-asserted source
Wei Jiang via ResearcherID

P21(cip)-Overexpression in the Mouse beta Cells Leads to the Improved Recovery from Streptozotocin-Induced Diabetes

Plos One
2009 | Journal article
WOSUID:

WOS:000272834200011

Contributors: Yang, Jie; Zhang, Weiqi; Jiang, Wei; Sun, Xiaoning; Han, Yuhua; Ding, Mingxiao; Shi, Yan; Deng, Hongkui
Source: Self-asserted source
Wei Jiang via ResearcherID

Differentiation of mouse nuclear transfer embryonic stem cells into functional pancreatic beta cells

Diabetologia
2008 | Journal article
WOSUID:

WOS:000258236200017

Contributors: Jiang, W.; Bai, Z.; Zhang, D.; Shi, Y.; Yong, J.; Chen, S.; Ding, M.; Deng, H.
Source: Self-asserted source
Wei Jiang via ResearcherID

Generation of Induced Pluripotent Stem Cells from Adult Rhesus Monkey Fibroblasts

Cell Stem Cell
2008 | Journal article
WOSUID:

WOS:000261670900006

Contributors: Liu, Haisong; Zhu, Fangfang; Yong, Jun; Zhang, Pengbo; Hou, Pingping; Li, Honggang; Jiang, Wei; Cai, Jun; Liu, Meng; Cui, Kai et al.
Source: Self-asserted source
Wei Jiang via ResearcherID

Generation of pancreatic islet cells and progenitor cells from embryonic stem cells

Cell Research
2008 | Journal article
WOSUID:

WOS:000260451000029

Contributors: Jiang, Wei; Chen, Song; Shi, Yan; Ding, Mingxiao; Deng, Hongkui
Source: Self-asserted source
Wei Jiang via ResearcherID

Short-term BMP-4 treatment initiates mesoderm induction in human embryonic stem cells

Blood
2008 | Journal article
WOSUID:

WOS:000253251100038

Contributors: Zhang, Pengbo; Li, Jian; Tan, Zhijia; Wang, Chengyan; Liu, Ting; Chen, Lin; Yong, Jun; Jiang, Wei; Sun, Xiaomeng; Du, Liying et al.
Source: Self-asserted source
Wei Jiang via ResearcherID

In vitro derivation of functional insulin-producing cells from human embryonic stem cells

Cell Research
2007 | Journal article
WOSUID:

WOS:000246609400018

Contributors: Jiang, Wei; Shi, Yan; Zhao, Dongxin; Chen, Song; Yong, Jun; Zhang, Jing; Qing, Tingting; Sun, Xiaoning; Zhang, Peng; Ding, Mingxiao et al.
Source: Self-asserted source
Wei Jiang via ResearcherID

Inducing embryonic stem cells to differentiate into pancreatic beta cells by a novel three-step approach with activin A and all-trans retinoic acid

Stem Cells
2005 | Journal article
WOSUID:

WOS:000229025200007

Contributors: Shi, Y; Hou, LL; Tang, FC; Jiang, W; Wang, PG; Ding, MX; Deng, HK
Source: Self-asserted source
Wei Jiang via ResearcherID

Peer review (45 reviews for 19 publications/grants)

Review activity for ACS biomaterials science & engineering. (1)
Review activity for Acta biomaterialia. (1)
Review activity for Advanced biosystems (1)
Review activity for Advanced science. (2)
Review activity for Biochemical and biophysical research communications. (1)
Review activity for Biochemistry and biophysics reports. (2)
Review activity for Biomolecules. (1)
Review activity for Cell insight. (3)
Review activity for Cell regeneration. (1)
Review activity for Cell reports. (4)
Review activity for Cells. (2)
Review activity for Cellular and molecular life sciences (2)
Review activity for iScience. (1)
Review activity for Materials today bio. (1)
Review activity for Molecular psychiatry. (1)
Review activity for Nature communications (1)
Review activity for Stem cell reports. (4)
Review activity for Stem cell research & therapy. (15)
Review activity for Stem cell research. (1)