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分子病毒學, 分子生物學, 微生物致病機轉, Molecular Virology, Molecular Biology, Microbial Pathogenesis

Activities

Education and qualifications (1)

National Yang-Ming University: Taipei, TW

1991-09-01 to 1998-06-30 | PhD (Microbiology and Immunology)
Education
Source: Self-asserted source
Pey-Jium Chang

Works (50 of 71)

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A Comparative Phenotypic and Genomic Analysis of Methicillin-Resistant Staphylococcus aureus ST45 Isolates From Cellulitis and Osteomyelitis in Taiwan

The Journal of Infectious Diseases
2024-09-23 | Journal article
Contributors: Kuo-Ti Peng; Pei-Chun Chen; Jiun-Liang Chen; Tsung-Yu Huang; Yi-Ho Peng; Ju-Fang Liu; Chiang-Wen Lee; Pey-Jium Chang
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Crossref

Assessment of the (Pro)renin Receptor Protein Expression in Organs

Current Issues in Molecular Biology
2024-02-25 | Journal article
Contributors: Teng-Yao Yang; Pey-Jium Chang; Yu-Shien Ko; Siou-Ru Shen; Shun-Fu Chang
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Crossref
grade
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Interaction and assembly of the DNA replication core proteins of Kaposi’s sarcoma-associated herpesvirus

Microbiology Spectrum
2023-12-12 | Journal article
Contributors: Lee-Wen Chen; Shie-Shan Wang; Li-Yu Chen; Hsiao-Yun Huang; Si-min He; Chien-Hui Hung; Chun-Liang Lin; Pey-Jium Chang; J. J. Miranda
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Crossref

Dickkopf-1 Acts as a Profibrotic Mediator in Progressive Chronic Kidney Disease

International Journal of Molecular Sciences
2023-04-21 | Journal article
Contributors: Yung-Chien Hsu; Cheng-Chih Chang; Ching-Chuan Hsieh; Yu-Ting Huang; Ya-Hsueh Shih; Hsiu-Ching Chang; Pey-Jium Chang; Chun-Liang Lin
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Characterization of Human Norovirus Nonstructural Protein NS1.2 Involved in the Induction of the Filamentous Endoplasmic Reticulum, Enlarged Lipid Droplets, LC3 Recruitment, and Interaction with NTPase and NS4

Viruses
2023-03-22 | Journal article
Contributors: Chien-Hui Hung; Ju-Bei Yen; Pey-Jium Chang; Lee-Wen Chen; Tsung-Yu Huang; Wan-Ju Tsai; Yu-Chin Tsai
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Kaposi’s Sarcoma-Associated Herpesvirus ORF50 Protein Represses Cellular MDM2 Expression via Suppressing the Sp1- and p53-Mediated Transactivation

International Journal of Molecular Sciences
2022-08-04 | Journal article
Contributors: Chia-I Lin; Shie-Shan Wang; Chien-Hui Hung; Pey-Jium Chang; Lee-Wen Chen
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Characterization of Methicillin-Resistant Staphylococcus aureus Isolates from Periprosthetic Joint Infections

Pathogens
2022-06-23 | Journal article
Contributors: Jiun-Liang Chen; Tsung-Yu Huang; Wei-Bin Hsu; Chiang-Wen Lee; Yao-Chang Chiang; Pey-Jium Chang; Kuo-Ti Peng
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Caspase-Mediated Cleavage of the Transcription Factor Sp3: Possible Relevance to Cancer and the Lytic Cycle of Kaposi’s Sarcoma-Associated Herpesvirus

Microbiology Spectrum
2022-02-23 | Journal article
Contributors: Li-Yu Chen; Lee-Wen Chen; Chien-Hui Hung; Chun-Liang Lin; Shie-Shan Wang; Pey-Jium Chang; JJ Miranda
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Crossref

The Pathogenic Bacteria of Deep Neck Infection in Patients with Type 1 Diabetes, Type 2 Diabetes, and Without Diabetes from Chang Gung Research Database

Microorganisms
2021-09-29 | Journal article
Contributors: Chih-Wei Luan; Chia-Yen Liu; Yao-Hsu Yang; Ming-Shao Tsai; Yao-Te Tsai; Cheng-Ming Hsu; Ching-Yuan Wu; Pey-Jium Chang; Geng-He Chang
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Identification and Characterization of Human Norovirus NTPase Regions Required for Lipid Droplet Localization, Cellular Apoptosis, and Interaction with the Viral P22 Protein

Microbiology Spectrum
2021-09-03 | Journal article
Contributors: Ju-Bei Yen; Lee-Wen Chen; Ling-Huei Wei; Chien-Hui Hung; Shie-Shan Wang; Chun-Liang Lin; Pey-Jium Chang; Gabriel I. Parra
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Crossref

Type 2 Diabetes Mellitus Increases Peritonsillar Abscess Susceptibility: Real-World Evidence

Clinical and Experimental Otorhinolaryngology
2021-08-01 | Journal article
Contributors: Ching-Lung Wu; Ming-Shao Tsai; Ta-Jen Lee; Yun-Ting Wang; Chia-Yen Liu; Yao-Hsu Yang; Yao-Te Tsai; Cheng-Ming Hsu; Ching-Yuan Wu; Pey-Jium Chang et al.
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Crossref

Nasal irrigation with Glycyrrhiza glabra extract for treatment of allergic rhinitis – A study of in vitro, in vivo and clinical trial

Journal of Ethnopharmacology
2021-07 | Journal article
Contributors: Geng-He Chang; Yu-Shih Lin; Ke-Hsin Hsu; Yu-Ching Cheng; Pei-Rung Yang; Ming-Shao Tsai; Yao-Te Tsai; Cheng-Ming Hsu; Pey-Jium Chang; Chung-Sheng Shi et al.
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GMI, an Immunomodulatory Peptide from Ganoderma microsporum, Restrains Periprosthetic Joint Infections via Modulating the Functions of Myeloid-Derived Suppressor Cells and Effector T Cells

International Journal of Molecular Sciences
2021-06-25 | Journal article
Contributors: Kuo-Ti Peng; Jiun-Liang Chen; Liang-Tseng Kuo; Pei-An Yu; Wei-Hsiu Hsu; Chiang-Wen Lee; Pey-Jium Chang; Tsung-Yu Huang
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High Risk of Peritonsillar Abscess in End-Stage Renal Disease Patients: A Nationwide Real-World Cohort Study

International Journal of Environmental Research and Public Health
2021-06-24 | Journal article
Contributors: Geng-He Chang; Ang Lu; Yao-Hsu Yang; Chia-Yen Liu; Pey-Jium Chang; Chuan-Pin Lee; Yao-Te Tsai; Cheng-Ming Hsu; Ching-Yuan Wu; Wei-Tai Shih et al.
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Curcumin Reinforces MiR-29a Expression, Reducing Mesangial Fibrosis in a Model of Diabetic Fibrotic Kidney via Modulation of CB1R Signaling

Processes
2021-04-15 | Journal article
Contributors: Yung-Chien Hsu; Pey-Jium Chang; Shih-Jiun Lin; Chia-Ching Liaw; Ya-Hsueh Shih; Lee-Wen Chen; Chun-Liang Lin
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Crossref
grade
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The Epstein-Barr Virus Lytic Protein BMLF1 Induces Upregulation of GRP78 Expression through ATF6 Activation

International Journal of Molecular Sciences
2021-04-14 | Journal article
Contributors: Lee-Wen Chen; Shie-Shan Wang; Chien-Hui Hung; Ya-Hui Hung; Chun-Liang Lin; Pey-Jium Chang
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Crossref
grade
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Sp3 Transcription Factor Cooperates with the Kaposi’s Sarcoma-Associated Herpesvirus ORF50 Protein To Synergistically Activate Specific Viral and Cellular Gene Promoters

Journal of Virology
2020-08-31 | Journal article
Contributors: Li-Yu Chen; Lee-Wen Chen; Kuo-Ti Peng; Chien-Hui Hung; Pey-Jium Chang; Shie-Shan Wang; Richard M. Longnecker
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De-Glycyrrhizinated Licorice Extract Attenuates High Glucose-Stimulated Renal Tubular Epithelial–Mesenchymal Transition via Suppressing the Notch2 Signaling Pathway

Cells
2020-01-05 | Journal article
Contributors: Yung-Chien Hsu; Pey-Jium Chang; Chun-Wu Tung; Ya-Hsueh Shih; Wen-Chiu Ni; Yi-Chen Li; Takuhiro Uto; Yukihiro Shoyama; Cheng Ho; Chun-Liang Lin
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Crossref

The Association Between Decompensated Liver Cirrhosis and Deep Neck Infection: Real-World Evidence

International Journal of Environmental Research and Public Health
2019-10-12 | Journal article
Contributors: Ming-Shao Tsai; Geng-He Chang; Wei-Ming Chen; Chia-Yen Liu; Meng-Hung Lin; Pey-Jium Chang; Tsung-Yu Huang; Yao-Te Tsai; Ching-Yuan Wu; Cheng-Ming Hsu et al.
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Crossref
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Comparison of Methicillin-Resistant Staphylococcus aureus Isolates from Cellulitis and from Osteomyelitis in a Taiwan Hospital, 2016–2018

Journal of Clinical Medicine
2019-06-07 | Journal article
Contributors: Kuo-Ti Peng; Tsung-Yu Huang; Yao-Chang Chiang; Yu-Yi Hsu; Fang-Yi Chuang; Chiang-Wen Lee; Pey-Jium Chang
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Crossref
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A KDM6A–KLF10 reinforcing feedback mechanism aggravates diabetic podocyte dysfunction

EMBO Molecular Medicine
2019-05 | Journal article
Contributors: Chun‐Liang Lin; Yung‐Chien Hsu; Yu‐Ting Huang; Ya‐Hsueh Shih; Ching‐Jen Wang; Wen‐Chih Chiang; Pey‐Jium Chang
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Crossref

Curcumin nanoparticles are a promising anti-bacterial and anti-inflammatory agent for treating periprosthetic joint infections

International Journal of Nanomedicine
2019-01 | Journal article
Contributors: Kuo-Ti Peng; Yao-Chang Chiang; Tsung-Yu Huang; Pei-Chun Chen; Pey-Jium Chang; Chiang-Wen Lee
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Crossref

Dysregulated expression of antioxidant enzymes in polyethylene particle-induced periprosthetic inflammation and osteolysis

PLOS ONE
2018-08-20 | Journal article
Contributors: Kuo-Ti Peng; Salah A Sheweita; Meng-Hsueh Tsai; Chiang-Wen Lee; Yao-Chang Chiang; Pei-Chun Chen; Chun-Chieh Chen; Chih-Hsiang Chang; Hsin-Nung Shih; Pey-Jium Chang
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Crossref

A common polymorphism decreases LRP1 mRNA stability and is associated with increased plasma factor VIII levels.

Biochimica et biophysica acta
2017 | Journal article
Contributors: Lee JD; Hsiao KM; Chang PJ; Chen CC; Kuo YW; Huang YC; Hsu HL; Lin YH; Wu CY; Lee M et al.
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Chang Gung University

CO-releasing molecules CORM2 attenuates angiotensin II-induced human aortic smooth muscle cell migration through inhibition of ROS/IL-6 generation and matrix metalloproteinases-9 expression.

Redox biology
2017 | Journal article
Contributors: Wu CM; Lee IT; Tsai MH; Lee CW; Hsu LF; Li SY; Chiang YC; Lee MH; Chen CH; Liang HF et al.
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Chang Gung University

Diabetes and risk of Kaposi's sarcoma: Effects of high glucose on reactivation and infection of Kaposi's sarcoma-associated herpesvirus

Oncotarget
2017 | Journal article
Contributors: Chang P.-J.; Yang Y.-H.; Chen P.-C.; Chen L.-W.; Wang S.-S.; Shih Y.-J.; Chen L.-Y.; Chen C.-J.; Hung C.-H.; Lin C.-L.
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Chang Gung University

Staphylococcus aureus biofilm elicits the expansion, activation and polarization of myeloid-derived suppressor cells in vivo and in vitro.

PloS one
2017 | Journal article
Contributors: Peng KT; Hsieh CC; Huang TY; Chen PC; Shih HN; Lee MS; Chang PJ
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Chang Gung University
grade
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The clinical roles of rheumatoid factor in the treatment of chronic hepatitis C infection

International Journal of Clinical and Experimental Medicine
2017 | Journal article
Contributors: Chen W.-M.; Chang K.-C.; Lin K.-M.; Wei K.-L.; Chang P.-J.; Chang T.-S.; Shen C.-H.; Tung S.-Y.
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Chang Gung University

Trichostatin A ameliorates renal tubulointerstitial fibrosis through modulation of the JNK-dependent Notch-2 signaling pathway.

Scientific reports
2017 | Journal article
Contributors: Tung CW; Hsu YC; Cai CJ; Shih YH; Wang CJ; Chang PJ; Lin CL
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Chang Gung University

Expression of Helios in gastric tumor cells predicts better survival in gastric cancer patients.

Journal of cancer research and clinical oncology
2016 | Journal article
Contributors: Chen WM; Wu CS; Liu JL; Yeh CM; Tseng L; Huang HC; Chang PJ; Wu SF
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Chang Gung University

Folate deficiency triggered apoptosis of synoviocytes: Role of overproduction of reactive oxygen species generated via NADPH oxidase/mitochondrial complex II and Calcium Perturbation

PLoS ONE
2016 | Journal article
Contributors: Hsu H.-C.; Chang W.-M.; Wu J.-Y.; Huang C.-C.; Lu F.-J.; Chuang Y.-W.; Chang P.-J.; Chen K.-H.; Hong C.-Z.; Yeh R.-H. et al.
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Chang Gung University

Hepatoprotective effect of resveratrol against ethanol-induced oxidative stress through induction of superoxide dismutase in vivo and in vitro

Experimental and Therapeutic Medicine
2016 | Journal article
Contributors: Chen W.-M.; Shaw L.-H.; Chang P.-J.; Tung S.-Y.; Chang T.-S.; Shen C.-H.; Hsieh Y.-Y.; Wei K.-L.
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Chang Gung University

Modulation of microRNA expression in subjects with metabolic syndrome and decrease of cholesterol efflux from macrophages via microRNA-33-mediated attenuation of ATP-binding cassette transporter A1 expression by statins

PLoS ONE
2016 | Journal article
Contributors: Chen W.-M.; Sheu W.H.-H.; Tseng P.-C.; Lee T.-S.; Lee W.-J.; Chang P.-J.; Chiang A.-N.
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Chang Gung University

Protective effects of MIR-29a on diabetic glomerular dysfunction by modulation of DKK1/Wnt/β-catenin signaling

Scientific Reports
2016 | Journal article
Contributors: Hsu Y.-C.; Chang P.-J.; Ho C.; Huang Y.-T.; Shih Y.-H.; Wang C.-J.; Lin C.-L.
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Chang Gung University

Risk of stroke in first-ever acute urinary retention: A 10-year population-based study

Urological Science
2016 | Journal article
Contributors: Chen C.-S.; Lin W.-Y.; Huang Y.-C.; Chang P.-J.; Huang K.-T.; Ho D.-R.
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Chang Gung University

The clinical outcomes of oldest old patients with tuberculosis treated by regimens containing rifampicin, isoniazid, and pyrazinamide

Clinical Interventions in Aging
2016 | Journal article
Contributors: Huang-Shen L.; Cheng C.-W.; Lin M.-S.; Chou Y.-L.; Chang P.-J.; Lin J.-C.; Ye J.-J.
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Chang Gung University

Activation of IL6/IGFIR confers poor prognosis of HBV-related hepatocellular carcinoma through induction of OCT4/NANOG expression

Clinical Cancer Research
2015 | Journal article
Contributors: Chang T.-S.; Wu Y.-C.; Chi C.-C.; Su W.-C.; Chang P.-J.; Lee K.-F.; Tung T.-H.; Wang J.; Liu J.-J.; Tung S.-Y. et al.
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Chang Gung University

Characterization of highly proliferative secondary tumor clusters along host blood vessels in malignant glioma

Molecular Medicine Reports
2015 | Journal article
Contributors: Wang T.-C.; Cheng C.-Y.; Yang W.-H.; Chen W.-C.; Chang P.-J.
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Chang Gung University

Transcriptional activation of Epstein–Barr virus BRLF1 by USF1 and Rta

Journal of General Virology
2015 | Journal article
Contributors: Hung C.-C.; Kuo C.-W.; Wang W.-H.; Chang T.-H.; Chang P.-J.; Chang L.-K.; Liu S.-T.
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Chang Gung University

Exploring the effects of tert-butylhydroperoxide induced liver injury using proteomic approach

Toxicology
2014 | Journal article
Contributors: Shen C.-H.; Tung S.-Y.; Huang W.-S.; Lu C.-C.; Lee K.-C.; Hsieh Y.-Y.; Chang P.-J.; Liang H.-F.; Chen J.-H.; Lin T.-H. et al.
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Chang Gung University

Lysophosphatidic acid enhanced the angiogenic capability of human chondrocytes by regulating Gi/NF-kB-dependent angiogenic factor expression

PLoS ONE
2014 | Journal article
Contributors: Chuang Y.-W.; Chang W.-M.; Chen K.-H.; Hong C.-Z.; Chang P.-J.; Hsu H.-C.
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Chang Gung University

Modulation of p75 neurotrophin receptor under hypoxic conditions induces migration and invasion of C6 glioma cells

Clinical and Experimental Metastasis
2014 | Journal article
Contributors: Wang T.-C.; Luo S.-J.; Lin C.-L.; Chang P.-J.; Chen M.-F.
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Chang Gung University

Regulation of autophagic activation by rta of Epstein-Barr virus via the extracellular signal-regulated kinase pathway

Journal of Virology
2014 | Journal article
Contributors: Hung C.-H.; Chen L.-W.; Wang W.-H.; Chang P.-J.; Chiu Y.-F.; Hung C.-C.; Lin Y.-J.; Liou J.-Y.; Tsai W.-J.; Hung C.-L. et al.
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Chang Gung University

The effects of gout on left atrial volume remodelling: A prospective echocardiographic study

Rheumatology (United Kingdom)
2014 | Journal article
Contributors: Pan K.-L.; Lin J.-C.; Lin C.-L.; Chen M.-C.; Chang P.-J.; Hsiao J.-F.; Chang S.-T.; Chung C.-M.
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Chang Gung University

Cellular senescence occurring in the rabbit medial collateral ligament during healing

Journal of Orthopaedic Research
2013 | Journal article
Contributors: Hsu W.-H.; Peng K.-T.; Lai L.-J.; Hung C.-H.; Chang P.-J.
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Chang Gung University

Colon cancer mesenchymal stem cells modulate the tumorigenicity of colon cancer through interleukin 6

Experimental Cell Research
2013 | Journal article
Contributors: Lin J.-T.; Wang J.-Y.; Chen M.-K.; Chen H.-C.; Chang T.-H.; Su B.-W.; Chang P.-J.
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Chang Gung University

Folate Deficiency Triggers an Oxidative-Nitrosative Stress-Mediated Apoptotic Cell Death and Impedes Insulin Biosynthesis in RINm5F Pancreatic Islet β-Cells: Relevant to the Pathogenesis of Diabetes.

PloS one
2013 | Journal article
Contributors: Hsu HC; Chiou JF; Wang YH; Chen CH; Mau SY; Ho CT; Chang PJ; Liu TZ; Chen CH
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Chang Gung University

Urine post equivalent daily cranberry juice consumption may opsonize uropathogenicity of Escherichia coli

Journal of Infection and Chemotherapy
2013 | Journal article
Contributors: Chen C.-S.; Ho D.-R.; Chang P.-J.; Lin W.-Y.; Huang Y.-C.
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Chang Gung University

Characterization and intracellular trafficking of epstein-barr virus BBLF1, a protein involved in virion maturation

Journal of Virology
2012 | Journal article
Contributors: Chiu Y.-F.; Sugden B.; Chang P.-J.; Chen L.-W.; Lin Y.-J.; Lan Y.-C.; Lai C.-H.; Liou J.-Y.; Liu S.-T.; Hung C.-H.
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Chang Gung University

Evidences of the inflammasome pathway in chronic prostatitis and chronic pelvic pain syndrome in an animal model

Prostate
2012 | Journal article
Contributors: Chen C.-S.; Chang P.-J.; Lin W.-Y.; Huang Y.-C.; Ho D.-R.
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Chang Gung University
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