Personal information

Transplant, Dendritic Cells, Immunology, Heat Shock Proteins, Transplant Immunology
United States, Brazil

Activities

Employment (3)

Massachusetts General Hospital: Boston, Massachusetts, US

2020-08-01 to present | Instructor (CTS, Surgery)
Employment
Source: Self-asserted source
Thiago J Borges

Brigham and Women's Hospital: Boston, MA, US

2017-12-11 to 2020-07-31 | Research Fellow (Medicine, Renal)
Employment
Source: Self-asserted source
Thiago J Borges

Centro Universitário La Salle: Canoas, RS, BR

2017-03-04 to 2017-11-30 | Assistant Professor
Employment
Source: Self-asserted source
Thiago J Borges

Education and qualifications (4)

Pontifícia Universidade Católica do Rio Grande do Sul: Porto Alegre, RS, BR

2015-12-01 to 2017-04-01 | Post-Doc
Education
Source: Self-asserted source
Thiago J Borges

Beth Israel Deaconess Medical Center: Boston, MA, US

2016-08-08 to 2017-01-01 | Post-Doc (Radiation Oncology)
Education
Source: Self-asserted source
Thiago J Borges

Pontifícia Universidade Católica do Rio Grande do Sul: Porto Alegre, RS, BR

2012-03-01 to 2015-11-29 | PhD
Education
Source: Self-asserted source
Thiago J Borges

Pontifícia Universidade Católica do Rio Grande do Sul: Porto Alegre, RS, BR

2010-03-01 to 2012-02-01 | MSc
Education
Source: Self-asserted source
Thiago J Borges

Professional activities (1)

American Heart Association: Dallas, Texas, US

Source: Self-asserted source
Thiago J Borges

Funding (3)

Targeting MHCII ubiquitination to achieve heart allograft tolerance

2023-04-01 to 2026-03-31 | Grant
American Heart Association (Dallas, US)
GRANT_NUMBER:

23CDA1049388

Source: check_circle
American Heart Association

Role of the Glycome in Promoting Immune Regulation after Transplantation

2020-01-01 to 2021-12-31 | Grant
American Heart Association (Dallas, US)
GRANT_NUMBER:

776630

Source: Self-asserted source
Thiago J Borges via DimensionsWizard

Role of the Glycome in Promoting Immune Regulation after Transplantation

2020-01-01 to 2021-12-31 | Grant
American Heart Association (Dallas, US)
GRANT_NUMBER:

20POST35210659

Source: check_circle
American Heart Association
grade
Preferred source (of 2)‎

Works (50 of 57)

Items per page:
Page 1 of 2

Innate extracellular Hsp70 inflammatory properties are mediated by the interaction of Siglec-E and LOX-1 receptors

2023-12-04 | Preprint
Contributors: Thiago J. Borges; Karina Lima; Ayesha Murshid; Isadora T. Lape; Yunlong Zhao; Maurício M. Rigo; Benjamin J. Lang; Shoib S. Siddiqui; Enfu Hui; Leonardo V. Riella et al.
Source: check_circle
Crossref

Immune Response of Transplanted Kidney Tissues Assembled from Organoid Building Blocks

2023-08-27 | Preprint
Contributors: Thiago J. Borges; Yoshikazu Ganchiku; Jeffrey O. Aceves; Ronald van Gaal; Sebastien G. M. Uzel; Jonathan E. Rubins; Kenichi Kobayashi; Ken Hiratsuka; Murat Tekguc; Ivy A. Rosales et al.
Source: check_circle
Crossref

Low-dose interleukin-2 promotes immune regulation in face transplantation: A pilot study

American Journal of Transplantation
2023-04 | Journal article
Contributors: Naoka Murakami; Thiago J. Borges; Thet Su Win; Phammela Abarzua; Sotirios Tasigiorgos; Branislav Kollar; Victor Barrera; Shannan Ho Sui; Jessica E. Teague; Ericka Bueno et al.
Source: check_circle
Crossref

MicroRNA-570 targets the HSP chaperone network, increases proteotoxic stress and inhibits mammary tumor cell migration.

Scientific reports
2022-09-16 | Journal article
Contributors: Okusha Y; Guerrero-Gimenez ME; Lang BJ; Thiago J Borges; Stevenson MA; Truman AW; Calderwood SK
Source: Self-asserted source
Thiago J Borges

Extracellular Hsp90α stimulates a unique innate gene profile in microglial cells with simultaneous activation of Nrf2 and protection from oxidative stress.

Cell stress & chaperones
2022-06-10 | Journal article
Contributors: Yuka Okusha; Lang BJ; Murshid A; Thiago J Borges; Holton KM; Joanne Clark-Matott; Doshi S; Ikezu T; Calderwood SK
Source: Self-asserted source
Thiago J Borges

Microbiota and the Response to Vaccines Against Respiratory Virus.

Frontiers in immunology
2022-05-06 | Journal article
Contributors: Gonçalves JIB; Thiago J Borges; de Souza APD
Source: Self-asserted source
Thiago J Borges

T cell depletion increases humoral response by favoring T follicular helper cells expansion.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
2022-04-15 | Journal article
Contributors: Gassen RB; Thiago J Borges; Maria Jose Perez-Saez; Hengcheng Zhang; Al Jurdi A; Laura Llinàs Mallol; Aoyama B; Lima M; Julio Pascual; Peter Sage et al.
Source: Self-asserted source
Thiago J Borges

Suboptimal antibody response against SARS-CoV-2 Omicron variant after third dose of mRNA vaccine in kidney transplant recipients.

Kidney international
2022-04-13 | Journal article
Contributors: Al Jurdi A; Gassen RB; Thiago J Borges; Lape IT; Morena L; Efe O; Solhjou Z; El Fekih R; Christa Deban; Bohan B et al.
Source: Self-asserted source
Thiago J Borges

T cell-attracting CCL18 chemokine is a dominant rejection signal during limb transplantation

Cell Reports Medicine
2022-03 | Journal article
Contributors: Thiago J. Borges; Phammela Abarzua; Rodrigo B. Gassen; Branislav Kollar; Mauricio Lima-Filho; Bruno T. Aoyama; Diana Gluhova; Rachael A. Clark; Sabina A. Islam; Bohdan Pomahac et al.
Source: check_circle
Crossref

Non-Invasive Monitoring for Rejection in Kidney Transplant Recipients After SARS-CoV-2 mRNA Vaccination.

Frontiers in immunology
2022-02-25 | Journal article
Contributors: Al Jurdi A; Gassen RB; Thiago J Borges; Solhjou Z; Hullekes FE; Lape IT; Efe O; Alghamdi A; Patel P; Choi JY et al.
Source: Self-asserted source
Thiago J Borges

Diminished antibody response against SARS-CoV-2 Omicron variant after third dose of mRNA vaccine in kidney transplant recipients

2022-01-06 | Preprint
Contributors: Ayman Al Jurdi; Rodrigo B. Gassen; Thiago J. Borges; Isadora T. Lape; Leela Morena; Orhan Efe; Zhabiz Solhjou; Rania El Fekih; Christa Deban; Brigid Bohan et al.
Source: check_circle
Crossref

Overexpression of PD-1 on T cells promotes tolerance in cardiac transplantation via ICOS-dependent mechanisms

JCI Insight
2021-12-22 | Journal article
Contributors: Thiago J. Borges; Naoka Murakami; Isadora T. Lape; Rodrigo B. Gassen; Kaifeng Liu; Songjie Cai; Joe Daccache; Kassem Safa; Tetsunosuke Shimizu; Shunsuke Ohori et al.
Source: check_circle
Crossref

Pediatric COVID-19 patients in South Brazil show abundant viral mRNA and strong specific anti-viral responses.

Nature communications
2021-11-25 | Journal article
Contributors: Tiago Fazolo; Karina Lima; Julia Crispim da Fontoura; Priscila de Souza; Gabriel Hilario; Renata Zorzetto; Júnior LR; Pscheidt VM; de Castilhos Ferreira Neto J; Haubert AF et al.
Source: Self-asserted source
Thiago J Borges

Extracellular Hsp90 and protection of neuronal cells through Nrf2.

Biochemical Society transactions
2021-11-01 | Journal article
Contributors: stuart calderwood; Thiago J Borges; Eguchi T; Lang BJ; Murshid A; Yuka Okusha; Prince TL
Source: Self-asserted source
Thiago J Borges

Immunological Impact of a Gluten-Free Dairy-Free Diet in Children With Kidney Disease: A Feasibility Study.

Frontiers in immunology
2021-06-02 | Journal article
Contributors: Maria Jose Perez-Saez; Uffing A; Leon J; Murakami N; Watanabe A; Thiago J Borges; Sabbisetti VS; Cureton P; Kenyon V; Keating L et al.
Source: Self-asserted source
Thiago J Borges

IL-21 treatment recovers follicular helper T cells and neutralizing antibody production in respiratory syncytial virus infection.

Immunology and cell biology
2020-12-04 | Journal article
Contributors: Gassen RB; Fazolo T; Nascimento de Freitas D; Thiago J Borges; Karina Lima; Géssica Luana Antunes; Maito F; Bueno Mendes DA; Báfica A; Rodrigues LC Jr et al.
Source: Self-asserted source
Thiago J Borges

Regulatory T cells engineered with TCR signaling–responsive IL-2 nanogels suppress alloimmunity in sites of antigen encounter

Science Translational Medicine
2020-11-11 | Journal article
Contributors: Siawosh K. Eskandari; Ina Sulkaj; Mariane B. Melo; Na Li; Hazim Allos; Juliano B. Alhaddad; Branislav Kollar; Thiago J. Borges; Arach S. Eskandari; Max A. Zinter et al.
Source: check_circle
Crossref

P2Y<sub>2</sub> receptor activation promotes esophageal cancer cells proliferation via ERK1/2 pathway.

European journal of pharmacology
2020-10-31 | Journal article
Contributors: Zaparte A; Cappellari AR; Brandão CA; de Souza JB; Thiago J Borges; Kist LW; Bogo MR; Luiz Zerbini; Ribeiro Pinto LF; Glaser T et al.
Source: Self-asserted source
Thiago J Borges

Donor myeloid derived suppressor cells (MDSCs) prolong allogeneic cardiac graft survival through programming of recipient myeloid cells in vivo.

Scientific reports
2020-08-28 | Journal article
Contributors: Songjie Cai; John Choi; Thiago J Borges; Zhang H; Ji Miao; Ichimura T; Li X; Xu S; Chu P; Siawosh K. Eskandari et al.
Source: Self-asserted source
Thiago J Borges

Host expression system modulates recombinant Hsp70 activity through post-translational modifications.

The FEBS journal
2020-03 | Journal article
Contributors: Rigo MM; Borges TJ; Lang BJ; Murshid A; Nitika; Wolfgeher D; Calderwood SK; Truman AW; Bonorino C
Source: Self-asserted source
Thiago J Borges via Europe PubMed Central
grade
Preferred source (of 2)‎

Accelerated chronic skin changes without allograft vasculopathy: A 10-year outcome report after face transplantation.

Surgery
2020-02 | Journal article
Contributors: Kollar B; Rizzo NM; Borges TJ; Haug V; Abdulrazzak O; Kauke M; Safi AF; Lian CG; Marty FM; Rutherford AE et al.
Source: Self-asserted source
Thiago J Borges via Europe PubMed Central

MMP3 Is a Non-invasive Biomarker of Rejection in Skin-Bearing Vascularized Composite Allotransplantation: A Multicenter Validation Study.

Frontiers in immunology
2019-11 | Journal article
Contributors: Kollar B; Uffing A; Borges TJ; Shubin AV; Aoyama BT; Dagot C; Haug V; Kauke M; Safi AF; Talbot SG et al.
Source: Self-asserted source
Thiago J Borges via Europe PubMed Central

Notch-1 Inhibition Promotes Immune Regulation in Transplantation Via Regulatory T Cell-Dependent Mechanisms.

Circulation
2019-07 | Journal article
Contributors: Magee CN; Murakami N; Borges TJ; Shimizu T; Safa K; Ohori S; Cai S; Uffing A; Azzi J; Elyaman W et al.
Source: Self-asserted source
Thiago J Borges via Europe PubMed Central

Immunological Outcomes Mediated Upon Binding of Heat Shock Proteins to Scavenger Receptors SCARF1 and LOX-1, and Endocytosis by Mononuclear Phagocytes.

Frontiers in immunology
2019-01 | Journal article
Contributors: Murshid A; Borges TJ; Bonorino C; Lang BJ; Calderwood SK
Source: Self-asserted source
Thiago J Borges via Europe PubMed Central

Conversion from tacrolimus to belatacept improves renal function in kidney transplant patients with chronic vascular lesions in allograft biopsy.

Clinical Kidney Journal
2018-12 | Journal article
Contributors: Pérez-Sáez MJ; Yu B; Uffing A; Murakami N; Borges TJ; Azzi J; El Haji S; Gabardi S; Riella LV
Source: Self-asserted source
Thiago J Borges via Europe PubMed Central

Chronic rejection of human face allografts.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
2018-11 | Journal article
Contributors: Krezdorn N; Lian CG; Wells M; Wo L; Tasigiorgos S; Xu S; Borges TJ; Frierson RM; Stanek E; Riella LV et al.
Source: Self-asserted source
Thiago J Borges via Europe PubMed Central

Increased levels of circulating MMP3 correlate with severe rejection in face transplantation

Scientific Reports
2018-10-08 | Journal article
Contributors: Branislav Kollar; Andrey Shubin; Thiago J. Borges; Sotirios Tasigiorgos; Thet Su Win; Christine G. Lian; Simon T. Dillon; Xuesong Gu; Iris Wyrobnik; George F. Murphy et al.
Source: check_circle
Crossref

March1-dependent modulation of donor MHC II on CD103+ dendritic cells mitigates alloimmunity

Nature Communications
2018-08-28 | Journal article
Contributors: Thiago J. Borges; Naoka Murakami; Felipe D. Machado; Ayesha Murshid; Benjamin J. Lang; Rafael L. Lopes; Laura M. Bellan; Mayuko Uehara; Krist H. Antunes; Maria José Pérez-Saéz et al.
Source: check_circle
Crossref

Vaccination with RSV M209-223 peptide promotes a protective immune response associated with reduced pulmonary inflammation.

Antiviral research
2018-07 | Journal article
Contributors: Fazolo T; Gassen RB; de Freitas DN; Borges TJ; Rigo MM; da Silva RD; Maito F; Cunha A; Gasparin Bueno Mendes DA; Báfica A et al.
Source: Self-asserted source
Thiago J Borges via Europe PubMed Central

Genotoxic stress induces Sca-1-expressing metastatic mammary cancer cells.

Molecular oncology
2018-06 | Journal article
Contributors: Gong J; Lang BJ; Weng D; Eguchi T; Murshid A; Borges TJ; Doshi S; Song B; Stevenson MA; Calderwood SK
Source: Self-asserted source
Thiago J Borges via Europe PubMed Central

Human regulatory T cells undergo self-inflicted damage via granzyme pathways upon activation.

JCI insight
2017-11 | Journal article
Contributors: Sula Karreci E; Eskandari SK; Dotiwala F; Routray SK; Kurdi AT; Assaker JP; Luckyanchykov P; Mihali AB; Maarouf O; Borges TJ et al.
Source: Self-asserted source
Thiago J Borges via Europe PubMed Central

RSV Downregulates IL-21/IL-21R On TFH Cells Via PD-L1 Induction In APCs Impairing Protective Humoral Responses

2017-10 | Other
OTHER-ID:

PPR23749

Contributors: Benedetti Gassen R; Fazolo T; Nascimento de Freitas D; Borges TJ; Maito F; Mendes DAGB; Bafica A; Rodrigues LC; Duarte de Souza AP; Bonorino C
Source: Self-asserted source
Thiago J Borges via Europe PubMed Central

Longitudinal immunological characterization of the first presensitized recipient of a face transplant.

JCI insight
2017-07 | Journal article
Source: Self-asserted source
Thiago J Borges via Europe PubMed Central

Pro-apoptotic effect of a Mycoplasma hyopneumoniae putative type I signal peptidase on PK(15) swine cells.

Veterinary microbiology
2017-03 | Journal article
Source: Self-asserted source
Thiago J Borges via Europe PubMed Central

Editorial: HSPs-Ambiguous Mediators of Immunity.

Frontiers in immunology
2016 | Journal article
Source: Self-asserted source
Thiago J Borges via Europe PubMed Central

Modulation of Alloimmunity by Heat Shock Proteins.

Frontiers in immunology
2016 | Journal article
Source: Self-asserted source
Thiago J Borges via Europe PubMed Central

The Scavenger Receptor SREC-I Cooperates with Toll-Like Receptors to Trigger Inflammatory Innate Immune Responses.

Frontiers in immunology
2016 | Journal article
Source: Self-asserted source
Thiago J Borges via Europe PubMed Central

Current status of alloimmunity.

Current opinion in nephrology and hypertension
2016-11 | Journal article
Source: Self-asserted source
Thiago J Borges via Europe PubMed Central
grade
Preferred source (of 2)‎

IL-10 is required for polarization of macrophages to M2-like phenotype by mycobacterial DnaK (heat shock protein 70)

Cytokine
2016-09 | Journal article
Contributors: Rafael L. Lopes; Thiago J. Borges; Rafael F. Zanin; Cristina Bonorino
Source: check_circle
Crossref

Codominant Role of Interferon-γ- and Interleukin-17-Producing T Cells During Rejection in Full Facial Transplant Recipients.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
2016-07 | Journal article
Source: Self-asserted source
Thiago J Borges via Europe PubMed Central

Mycoplasma hyopneumoniae and Mycoplasma flocculare differential domains from orthologous surface proteins induce distinct cellular immune responses in mice.

Veterinary microbiology
2016-07 | Journal article
Source: Self-asserted source
Thiago J Borges via Europe PubMed Central

Erratum: Severe acute interstitial nephritis after combination immune-checkpoint inhibitor therapy for metastatic melanoma.

Clinical Kidney Journal
2016-06 | Journal article
Contributors: Murakami N; Borges TJ; Yamashita M; Riella LV
Source: Self-asserted source
Thiago J Borges via Europe PubMed Central

Severe acute interstitial nephritis after combination immune-checkpoint inhibitor therapy for metastatic melanoma.

Clinical kidney journal
2016-06 | Journal article
Source: Self-asserted source
Thiago J Borges via Europe PubMed Central

Emerging roles for scavenger receptor SREC-I in immunity

Cytokine
2015 | Journal article
EID:

2-s2.0-84939777720

Contributors: Murshid, A.; Borges, T.J.; Calderwood, S.K.
Source: Self-asserted source
Thiago J Borges via Scopus - Elsevier

Salt accelerates allograft rejection through serum- And glucocorticoid-regulated kinase-1-Dependent inhibition of regulatory T cells

Journal of the American Society of Nephrology
2015 | Journal article
EID:

2-s2.0-84942905660

Contributors: Safa, K.; Ohori, S.; Borges, T.J.; Uehara, M.; Batal, I.; Shimizu, T.; Magee, C.N.; Belizaire, R.; Abdi, R.; Wu, C. et al.
Source: Self-asserted source
Thiago J Borges via Scopus - Elsevier

Scavenger receptor SREC-I mediated entry of TLR4 into lipid microdomains and triggered inflammatory cytokine release in RAW 2647 cells upon LPS activation

PLoS ONE
2015 | Journal article
EID:

2-s2.0-84926645180

Contributors: Murshid, A.; Gong, J.; Prince, T.; Borges, T.J.; Calderwood, S.K.
Source: Self-asserted source
Thiago J Borges via Scopus - Elsevier

Scavenger receptor SREC-I promotes double stranded RNA-mediated TLR3 activation in human monocytes

Immunobiology
2015 | Journal article
EID:

2-s2.0-84988267207

Contributors: Murshid, A.; Gong, J.; Ahmad, R.; Borges, T.J.; Calderwood, S.K.
Source: Self-asserted source
Thiago J Borges via Scopus - Elsevier

Extracellular mycobacterial DnaK polarizes macrophages to the M2-like phenotype

PLoS ONE
2014 | Journal article
EID:

2-s2.0-84912569818

Contributors: Lopes, R.L.; Borges, T.J.; Araújo, J.F.; Pinho, N.G.; Bergamin, L.S.; Battastini, A.M.O.; Muraro, S.P.; Souza, A.P.D.; Zanin, R.F.; Bonorino, C.
Source: Self-asserted source
Thiago J Borges via Scopus - Elsevier

Extracellular Hsp70 inhibits pro-inflammatory cytokine production by IL-10 driven down-regulation of C/EBPβ and C/EBPδ

International Journal of Hyperthermia
2013 | Journal article
EID:

2-s2.0-84881157196

Contributors: Borges, T.J.; Lopes, R.L.; Pinho, N.G.; Machado, F.D.; Souza, A.P.D.; Bonorino, C.
Source: Self-asserted source
Thiago J Borges via Scopus - Elsevier

Implication of purinergic P2X7 receptor in M. tuberculosis infection and host interaction mechanisms: A mouse model study

Immunobiology
2013 | Journal article
EID:

2-s2.0-84878613116

Contributors: Santos, A.A.; Rodrigues-Junior, V.; Zanin, R.F.; Borges, T.J.; Bonorino, C.; Coutinho-Silva, R.; Takyia, C.M.; Santos, D.S.; Campos, M.M.; Morrone, F.B.
Source: Self-asserted source
Thiago J Borges via Scopus - Elsevier
Items per page:
Page 1 of 2

Peer review (23 reviews for 8 publications/grants)

Review activity for American journal of transplantation. (14)
Review activity for Cell stress & chaperones. (1)
Review activity for International journal of biological macromolecules. (2)
Review activity for International journal of molecular sciences. (1)
Review activity for iScience. (1)
Review activity for PloS one. (1)
Review activity for Transplant immunology. (1)
Review activity for Transplantation reviews. (2)