Personal information

flavoprotein and flavoenzymes, antibiotic discovery and development, fast kinetics

Activities

Employment (4)

Inserm DR Nord - Ouest: Lille, FR

2024 to present | Chargé de recherche de classe normale (CRCN) at INSERM (INSERM U1019 - Centre of Infection and Immunology de Lille - Institut Pasteur de Lille - Institut de Biologie de Lille)
Employment
Source: Self-asserted source
Ernesto Anoz-Carbonell

Inserm DR Nord - Ouest: Lille, FR

2021 to 2024 | Postdoctoral researcher (INSERM U1019 - Centre of Infection and Immunology de Lille - Institut Pasteur de Lille - Institut de Biologie de Lille)
Employment
Source: Self-asserted source
Ernesto Anoz-Carbonell

University of Zaragoza: Zaragoza, Zaragoza, ES

2015 to 2021 | MSc and PhD student (Departamento de Bioquímica y Biología Molecular y Celular - Departamento de Microbiología, Pediatría, Radiología y Salud Pública - BIFI)
Employment
Source: Self-asserted source
Ernesto Anoz-Carbonell

Centre of Microbial and Plant Genetics: Leuven, BE

2015-03 to 2015-06 | Bachelor research stay (Plant Growth Promoting Rhizobacteria)
Employment
Source: Self-asserted source
Ernesto Anoz-Carbonell

Education and qualifications (3)

Universidad de Zaragoza: Zaragoza, ES

2016 to 2021 | Ph.D. in Biochemistry and Molecular Biology
Qualification
Source: Self-asserted source
Ernesto Anoz-Carbonell

Universidad de Zaragoza: Zaragoza, ES

2015 to 2016 | MSc in Molecular an Cellular Biology
Qualification
Source: Self-asserted source
Ernesto Anoz-Carbonell

Universidad de Zaragoza: Zaragoza, ES

2011 to 2015 | Bachelor Degree in Biotechnology
Qualification
Source: Self-asserted source
Ernesto Anoz-Carbonell

Works (16)

A Novel Natural Siderophore Antibiotic Conjugate Reveals a Chemical Approach to Macromolecule Coupling

ACS Central Science
2023 | Journal article
EID:

2-s2.0-85178085687

Part of ISSN: 23747951 23747943
Contributors: Caradec, T.; Anoz-Carbonell, E.; Petrov, R.; Billamboz, M.; Antraygues, K.; Cantrelle, F.-X.; Boll, E.; Beury, D.; Hot, D.; Drobecq, H. et al.
Source: Self-asserted source
Ernesto Anoz-Carbonell via Scopus - Elsevier

Counterintuitive structural and functional effects due to naturally occurring mutations targeting the active site of the disease-associated NQO1 enzyme*

FEBS Journal
2023 | Journal article
EID:

2-s2.0-85143388129

Part of ISSN: 17424658 1742464X
Contributors: Pacheco-García, J.L.; Anoz-Carbonell, E.; Loginov, D.S.; Kavan, D.; Salido, E.; Man, P.; Medina, M.; Pey, A.L.
Source: Self-asserted source
Ernesto Anoz-Carbonell via Scopus - Elsevier

Allosteric Communication in the Multifunctional and Redox NQO1 Protein Studied by Cavity‐Making Mutations

Antioxidants
2022 | Journal article
EID:

2-s2.0-85131635705

Part of ISSN: 20763921
Contributors: Pacheco‐garcia, J.L.; Loginov, D.S.; Anoz‐carbonell, E.; Vankova, P.; Palomino‐morales, R.; Salido, E.; Man, P.; Medina, M.; Naganathan, A.N.; Pey, A.L.
Source: Self-asserted source
Ernesto Anoz-Carbonell via Scopus - Elsevier

Targeting HIF-1α Function in Cancer through the Chaperone Action of NQO1: Implications of Genetic Diversity of NQO1

Journal of Personalized Medicine
2022 | Journal article
EID:

2-s2.0-85130137897

Part of ISSN: 20754426
Contributors: Salido, E.; Timson, D.J.; Betancor-Fernández, I.; Palomino-Morales, R.; Anoz-Carbonell, E.; Pacheco-García, J.L.; Medina, M.; Pey, A.L.
Source: Self-asserted source
Ernesto Anoz-Carbonell via Scopus - Elsevier

Different phenotypic outcome due to site-specific phosphorylation in the cancer-associated NQO1 enzyme studied by phosphomimetic mutations

Archives of Biochemistry and Biophysics
2022-10 | Journal article
Contributors: Juan Luis Pacheco-Garcia; Ernesto Anoz-Carbonell; Dmitry S. Loginov; Pavla Vankova; Eduardo Salido; Petr Man; Milagros Medina; Rogelio Palomino-Morales; Angel L. Pey
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Crossref
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Cofactors and pathogens: Flavin mononucleotide and flavin adenine dinucleotide (FAD) biosynthesis by the FAD synthase from Brucella ovis

IUBMB Life
2022-07 | Journal article
Contributors: Andrea Moreno; Victor Taleb; María Sebastián; Ernesto Anoz‐Carbonell; Marta Martínez‐Júlvez; Milagros Medina
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Crossref
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Selective targeting of human and animal pathogens of the helicobacter genus by flavodoxin inhibitors: Efficacy, synergy, resistance and mechanistic studies

International Journal of Molecular Sciences
2021 | Journal article
EID:

2-s2.0-85115139834

Part of ISSN: 14220067 16616596
Contributors: Salillas, S.; Galano‐frutos, J.J.; Mahía, A.; Maity, R.; Conde‐giménez, M.; Anoz‐carbonell, E.; Berlamont, H.; Velazquez‐campoy, A.; Touati, E.; Mamat, U. et al.
Source: Self-asserted source
Ernesto Anoz-Carbonell via Scopus - Elsevier

Structural basis of the pleiotropic and specific phenotypic consequences of missense mutations in the multifunctional NAD(P)H:quinone oxidoreductase 1 and their pharmacological rescue.

Redox biology
2021-08 | Journal article
Contributors: Pacheco-Garcia JL; Anoz-Carbonell E; Vankova P; Kannan A; Palomino-Morales R; Mesa-Torres N; Salido E; Man P; Medina M; Naganathan AN et al.
Source: Self-asserted source
Ernesto Anoz-Carbonell via Europe PubMed Central
grade
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Human riboflavin kinase: Species-specific traits in the biosynthesis of the FMN cofactor

FASEB Journal
2020 | Journal article
EID:

2-s2.0-85087724283

Part of ISBN:

15306860 08926638

Contributors: Anoz-Carbonell, E.; Rivero, M.; Polo, V.; Velázquez-Campoy, A.; Medina, M.
Source: Self-asserted source
Ernesto Anoz-Carbonell via Scopus - Elsevier

The Catalytic Cycle of the Antioxidant and Cancer-Associated Human NQO1 Enzyme: Hydride Transfer, Conformational Dynamics and Functional Cooperativity.

Antioxidants (Basel, Switzerland)
2020-08 | Journal article
Contributors: Anoz-Carbonell E; Timson DJ; Pey AL; Medina M
Source: Self-asserted source
Ernesto Anoz-Carbonell via Europe PubMed Central
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In silicodiscovery and biological validation of ligands of FAD synthase, a promising new antimicrobial target

2020-04-22 | Preprint
Contributors: Isaias Lans; Ernesto Anoz-Carbonell; Karen Palacio-Rodríguez; José Antonio Aínsa; Milagros Medina; Pilar Cossio
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Crossref
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Mutation of aspartate 238 in FAD synthase isoform 6 increases the specific activity by weakening the FAD binding

International Journal of Molecular Sciences
2019 | Journal article
EID:

2-s2.0-85076372358

Contributors: Leone, P.; Galluccio, M.; Quarta, S.; Anoz-Carbonell, E.; Medina, M.; Indiveri, C.; Barile, M.
Source: Self-asserted source
Ernesto Anoz-Carbonell via Scopus - Elsevier
grade
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Mycobacterial aminoglycoside acetyltransferases: A little of drug resistance, and a lot of other roles

Frontiers in Microbiology
2019 | Journal article
EID:

2-s2.0-85064394706

Contributors: Sanz-García, F.; Anoz-Carbonell, E.; Pérez-Herrán, E.; Martín, C.; Lucía, A.; Rodrigues, L.; Aínsa, J.E.
Source: Self-asserted source
Ernesto Anoz-Carbonell via Scopus - Elsevier

Towards the competent conformation for catalysis in the ferredoxin-NADP<sup>+</sup> reductase from the Brucella ovis pathogen

Biochimica et Biophysica Acta - Bioenergetics
2019 | Journal article
EID:

2-s2.0-85071090076

Contributors: Pérez-Amigot, D.; Taleb, V.; Boneta, S.; Anoz-Carbonell, E.; Sebastián, M.; Velázquez-Campoy, A.; Polo, V.; Martínez-Júlvez, M.; Medina, M.
Source: Self-asserted source
Ernesto Anoz-Carbonell via Scopus - Elsevier

Discovery of antimicrobial compounds targeting bacterial type FAD synthetases

Journal of Enzyme Inhibition and Medicinal Chemistry
2018 | Journal article
EID:

2-s2.0-85038559761

Contributors: Sebastián, M.; Anoz-Carbonell, E.; Gracia, B.; Cossio, P.; Aínsa, J.A.; Lans, I.; Medina, M.
Source: Self-asserted source
Ernesto Anoz-Carbonell via Scopus - Elsevier

A natural chimeric Pseudomonas bacteriocin with novel pore-forming activity parasitizes the ferrichrome transporter

mBio
2017 | Journal article
EID:

2-s2.0-85014791894

Contributors: Ghequire, M.G.K.; Kemland, L.; Anoz-Carbonell, E.; Buchanan, S.K.; De Mot, R.
Source: Self-asserted source
Ernesto Anoz-Carbonell via Scopus - Elsevier