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Works (21)

Characterization of brain transduction capability of a BBB-penetrant, peptide-displaying AAV vector in mice, rats and non-human primates

2024-05-30 | Preprint
Contributors: Ruben Hernandez-Alcoceba; Maria Bunuales; Angeles Garduno; Miguel Chillon; Assumpció Bosch; Manuela Gonzalez-Aparicio; Maria Espelosin; Marta Garcia-Gomara; Alberto Rico; Ana Garcia-Osta et al.
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Crossref

Viral vector-mediated expression of NaV1.1, after seizure onset, reduces epilepsy in mice with Dravet syndrome

Journal of Clinical Investigation
2023-05-16 | Journal article
Part of ISSN: 1558-8238
Contributors: Saja Fadila; Bertrand BEUCHER; Iria Gonzalez-Dopeso Reyes; Anat Mavashov; Marina Brusel; Karen Anderson; Caroline Ismeurt; Ethan Goldberg; Ana Ricobaraza; Ruben Hernandez-Alcoceba et al.
Source: Self-asserted source
Ruben Hernandez-Alcoceba

Application of a split‐Cre system for high‐capacity adenoviral vector amplification

Biotechnology Journal
2023-03 | Journal article
Contributors: Manuela Gonzalez‐Aparicio; Maria Bunuales; Iñaki Ortiz de Landazuri; Jesus Prieto; Ruben Hernandez‐Alcoceba
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Crossref

Preclinical model for phenotypic correction of dystrophic epidermolysis bullosa by in vivo CRISPR-Cas9 delivery using adenoviral vectors

Molecular Therapy - Methods & Clinical Development
2022-12 | Journal article
Part of ISSN: 2329-0501
Contributors: Marta García; Jose Bonafont; Jesús Martínez-Palacios; Rudan Xu; Giandomenico Turchiano; Stina Svensson; Adrian J. Thrasher; Fernando Larcher; Marcela Del Rio; Rubén Hernández-Alcoceba et al.
Source: Self-asserted source
Ruben Hernandez-Alcoceba

Galectin-3 inhibition boosts the therapeutic efficacy of Semliki Forest virus in pediatric osteosarcoma

Molecular Therapy - Oncolytics
2022-09 | Journal article
Part of ISSN: 2372-7705
Contributors: Guillermo Herrador-Cañete; Marta Zalacain; Sara Labiano; Virginia Laspidea; Montserrat Puigdelloses; Lucía Marrodan; Marc Garcia-Moure; Marisol Gonzalez-Huarriz; Javier Marco-Sanz; Iker Ausejo-Mauleon et al.
Source: Self-asserted source
Ruben Hernandez-Alcoceba

High value of 64Cu as a tool to evaluate the restoration of physiological copper excretion after gene therapy in Wilson’s disease

Molecular Therapy - Methods & Clinical Development
2022-09 | Journal article
Part of ISSN: 2329-0501
Contributors: Oihana Murillo; Maria Collantes; Cristina Gazquez; Daniel Moreno; Ruben Hernandez-Alcoceba; Miren Barberia; Margarita Ecay; Blanche Tamarit; Anne Douar; Veronica Ferrer et al.
Source: Self-asserted source
Ruben Hernandez-Alcoceba

Oncolytic DNX-2401 Virus for Pediatric Diffuse Intrinsic Pontine Glioma

New England Journal of Medicine
2022-06-30 | Journal article
Part of ISSN: 0028-4793
Part of ISSN: 1533-4406
Contributors: Jaime Gállego Pérez-Larraya; Marc Garcia-Moure; Sara Labiano; Ana Patiño-García; Jessica Dobbs; Marisol Gonzalez-Huarriz; Marta Zalacain; Lucia Marrodan; Naiara Martinez-Velez; Montserrat Puigdelloses et al.
Source: Self-asserted source
Ruben Hernandez-Alcoceba

Exogenous NaV1.1 activity in excitatory and inhibitory neurons reverts Dravet syndrome comorbidities when delivered post-symptom onset in mice with Dravet

2022-06-12 | Preprint
Contributors: Saja Fadila; Bertrand Beucher; Iria González-Dopeso Reyes; Anat Mavashov; Marina Brusel; Karen Anderson; Ethan M Goldberg; Ana Ricobaraza; Ruben Hernandez-Alcoceba; Eric J Kremer et al.
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Crossref

Broad virus inactivation using inorganic micro/nano-particulate materials

Materials Today Bio
2022-01 | Journal article
Part of ISSN: 2590-0064
Contributors: Sergio Rius-Rocabert; Javier Arranz-Herrero; Adolfo Fernández-Valdés; Marzia Marciello; Sandra Moreno; Francisco Llinares-Pinel; Jesus Presa; Rubén Hernandez-Alcoceba; Roberto López-Píriz; Ramón Torrecillas et al.
Source: Self-asserted source
Ruben Hernandez-Alcoceba

Gene therapies and COVID-19 vaccines: a necessary discussion in relation with viral vector-based approaches

Orphanet Journal of Rare Diseases
2021-12 | Journal article
Part of ISSN: 1750-1172
Contributors: Angel Aledo-Serrano; Antonio Gil-Nagel; Julian Isla; Ana Mingorance; Fernando Mendez-Hermida; Ruben Hernandez-Alcoceba
Source: Self-asserted source
Ruben Hernandez-Alcoceba

Gene supplementation of CYP27A1 in the liver restores bile acid metabolism in a mouse model of cerebrotendinous xanthomatosis

Molecular Therapy - Methods & Clinical Development
2021-09 | Journal article
Part of ISSN: 2329-0501
Contributors: Sara Lumbreras; Ana Ricobaraza; Lucia Baila-Rueda; Manuela Gonzalez-Aparicio; Lucia Mora-Jimenez; Iker Uriarte; Maria Bunuales; Matias A. Avila; Maria J. Monte; Jose J.G. Marin et al.
Source: Self-asserted source
Ruben Hernandez-Alcoceba

Transfer of SCN1A to the brain of adolescent mouse model of Dravet syndrome improves epileptic, motor, and behavioral manifestations

Molecular Therapy - Nucleic Acids
2021-09 | Journal article | Author
Part of ISSN: 2162-2531
Contributors: Lucía Mora; Valencia M; Rocio Sanchez-Carpintero; Jan Tønnesen ; Saja Fadila; Moran Rubinstein; Manuela Gonzalez-Aparicio; María Buñuales; Eva Fernandez-Pierola; Maria Jesus Nicolas et al.
Source: Self-asserted source
Ruben Hernandez-Alcoceba

Understanding the Molecular Mechanism of miR-877-3p Could Provide Potential Biomarkers and Therapeutic Targets in Squamous Cell Carcinoma of the Cervix

Cancers
2021-04 | Journal article | Author
Contributors: Saioa Mendaza; Joaquin Fernandez-Irigoyen; ENRIQUE SANTAMARIA; Imanol Arozarena; David Guerrero-Setas; Tamara Zudaire; Rosa Guarch; August Vidal; José-Santos Salas; Xavier Matias-Guiu et al.
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Multidisciplinary Digital Publishing Institute

Adenovirus-Mediated Inducible Expression of a PD-L1 Blocking Antibody in Combination with Macrophage Depletion Improves Survival in a Mouse Model of Peritoneal Carcinomatosis

International Journal of Molecular Sciences
2021-04-17 | Journal article | Author
Part of ISSN: 1422-0067
Contributors: Maria Buñuales; Maria Cristina Ballesteros-Briones; Manuela Gonzalez-Aparicio; Sandra Hervas-Stubbs; Eva Martisova; Uxua Mancheño; Ana Ricobaraza; Sara Lumbreras; Cristian Smerdou; Ruben Hernandez-Alcoceba
Source: Self-asserted source
Ruben Hernandez-Alcoceba
grade
Preferred source (of 3)‎

Local administration of IL-12 with an HC vector results in local and metastatic tumor control in pediatric osteosarcoma

Molecular Therapy - Oncolytics
2021-03 | Journal article
Part of ISSN: 2372-7705
Contributors: Marta Zalacain; María Bunuales; Lucía Marrodan; Sara Labiano; Marisol Gonzalez-Huarriz; Naiara Martinez-Vélez; Virginia Laspidea; Montse Puigdelloses; Marc García-Moure; Manuela Gonzalez-Aparicio et al.
Source: Self-asserted source
Ruben Hernandez-Alcoceba

Understanding the Potential Role of Sirtuin 2 on Aging: Consequences of SIRT2.3 Overexpression in Senescence

International Journal of Molecular Sciences
2021-03-18 | Journal article
Contributors: Noemi Sola-Sevilla; Ana Ricobaraza; Ruben Hernandez-Alcoceba; Maria S. Aymerich; Rosa M. Tordera; Elena Puerta
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Alterations of the Hippocampal Neurogenic Niche in a Mouse Model of Dravet Syndrome

Frontiers in Cell and Developmental Biology
2020-07-21 | Journal article
Part of ISSN: 2296-634X
Contributors: Soraya Martín-Suárez; Oihane Abiega; Ana Ricobaraza; Rubén Hernandez-Alcoceba; Juan Manuel Encinas
Source: Self-asserted source
Ruben Hernandez-Alcoceba

High-Capacity Adenoviral Vectors: Expanding the Scope of Gene Therapy

International Journal of Molecular Sciences
2020-05-21 | Journal article
Contributors: Ana Ricobaraza; Manuela Gonzalez-Aparicio; Lucia Mora-Jimenez; Sara Lumbreras; Ruben Hernandez-Alcoceba
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Crossref

Bektore biral terapeutiko baten efikazia eta toxizitateaten ebaluazioa Wilson gaixotasundun saguetan

2019-05-20 | Conference paper
Contributors: Gloria Gonzalez Aseguinolaza; Ruben Hernandez Alcoceba; Jean Philippe Combal; Bernard Bénichou; Veronica Ferrer; Iñigo Navarro Blasco; Iker Uriarte Díaz-Varela; Itziar Cenzano Armendariz; Miren Barberia Urteaga; Cristina Gazquez López et al.
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Crossref

Inhibition of adenovirus infection by mifepristone

Antiviral Research
2018-11 | Journal article
Contributors: José A. Marrugal-Lorenzo; Ana Serna-Gallego; Loreto González-González; Maria Buñuales; Joanna Poutou; Jerónimo Pachón; Manuela Gonzalez-Aparicio; Ruben Hernandez-Alcoceba; Javier Sánchez-Céspedes
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Crossref

Adaptation of vectors and drug-inducible systems for controlled expression of transgenes in the tumor microenvironment

Journal of Controlled Release
2017-12 | Journal article
Contributors: Joanna Poutou; Maria Bunuales; Manuela Gonzalez-Aparicio; Beatriz German; Ines Zugasti; Ruben Hernandez-Alcoceba
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Crossref

Peer review (10 reviews for 7 publications/grants)

Review activity for Cells. (1)
Review activity for Communications biology. (1)
Review activity for Experimental neurology. (1)
Review activity for International journal of molecular sciences. (1)
Review activity for Molecular therapy. (2)
Review activity for Prostaglandins & other lipid mediators. (3)
Review activity for Viruses. (1)