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Scopus Author ID: 7102383847

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Employment (5)

University of Illinois at Chicago: Chicago, IL, US

2022-08-16 to present | Professor (Pharmaceutical Sciences)
Employment
Source: Self-asserted source
Paul R. Carlier

Virginia Polytechnic Institute and State University: Blacksburg, VA, US

2007-05 to 2022-08-09 | Professor (Chemistry)
Employment
Source: Self-asserted source
Paul R. Carlier

Virginia Polytechnic Institute and State University: Blacksburg, VA, US

2000-08 to 2007-04 | Associate Professor (Chemistry)
Employment
Source: Self-asserted source
Paul R. Carlier

Hong Kong University of Science and Technology: Clear Water Bay, Kowloon, HK

2000-05 to 2000-07 | Associate Professor (Chemistry)
Employment
Source: Self-asserted source
Paul R. Carlier

Hong Kong University of Science and Technology: Clear Water Bay, Kowloon, HK

1991-09 to 2000-04 | Assistant Professor (Chemistry)
Employment
Source: Self-asserted source
Paul R. Carlier

Education and qualifications (2)

Massachusetts Institute of Technology: Cambridge, MA, US

1983-08 to 1988-02 | Ph. D. (Chemistry)
Education
Source: Self-asserted source
Paul R. Carlier

Hamilton College: Clinton, NY, US

1979-08 to 1983-05 | B. A. (Chemistry)
Education
Source: Self-asserted source
Paul R. Carlier

Works (50 of 99)

Items per page:
Page 1 of 2

Mosquito Acetylcholinesterase as a Target for Novel Phenyl-Substituted Carbamates

International Journal of Environmental Research and Public Health
2019-04 | Journal article | Author
DOI: 10.3390/ijerph16091500
Contributors: James M. Mutunga; Ming Ma; Qiao-Hong Chen; Joshua A. Hartsel; Dawn Wong; Sha Ding; Max Totrov; Paul R. Carlier; Jeff Bloomquist
Source: check_circle
Multidisciplinary Digital Publishing Institute

Bivalent carbamates as novel control agents of the malaria mosquito, Anopheles gambiae

Chimia
2016 | Journal article
DOI: 10.2533/chimia.2016.704
EID:

2-s2.0-84992083514
Contributors: Mutunga, J.M.; Chen, Q.-H.; Wong, D.M.; Lam, P.C.-H.; Li, J.; Totrov, M.M.; Gross, A.D.; Carlier, P.R.; Bloomquist, J.R.
Source: Self-asserted source
Paul R. Carlier via Scopus - Elsevier

Parallel inhibition of amino acid efflux and growth of erythrocytic Plasmodium falciparum by mefloquine and non-piperidine analogs: Implication for the mechanism of antimalarial action

Bioorganic and Medicinal Chemistry Letters
2016 | Journal article
DOI: 10.1016/j.bmcl.2016.08.005
EID:

2-s2.0-84985993104
Contributors: Ghavami, M.; Dapper, C.H.; Dalal, S.; Holzschneider, K.; Klemba, M.; Carlier, P.R.
Source: Self-asserted source
Paul R. Carlier via Scopus - Elsevier

Toxicology of potassium channel-directed compounds in mosquitoes

NeuroToxicology
2016 | Journal article
DOI: 10.1016/j.neuro.2016.05.021
EID:

2-s2.0-85006789622
Contributors: Larson, N.R.; Carlier, P.R.; Gross, A.D.; Islam, R.M.; Ma, M.; Sun, B.; Totrov, M.M.; Yadav, R.; Bloomquist, J.R.
Source: Self-asserted source
Paul R. Carlier via Scopus - Elsevier

3-Oxoisoxazole-2(3H)-carboxamides and isoxazol-3-yl carbamates: Resistance-breaking acetylcholinesterase inhibitors targeting the malaria mosquito, Anopheles gambiae

Bioorganic and Medicinal Chemistry
2015 | Journal article
DOI: 10.1016/j.bmc.2015.01.026
EID:

2-s2.0-84923566760
Contributors: Verma, A.; Wong, D.M.; Islam, R.; Tong, F.; Ghavami, M.; Mutunga, J.M.; Slebodnick, C.; Li, J.; Viayna, E.; Lam, P.C.-H. et al.
Source: Self-asserted source
Paul R. Carlier via Scopus - Elsevier

Carbamate and pyrethroid resistance in the akron strain of Anopheles gambiae

Pesticide Biochemistry and Physiology
2015 | Journal article
DOI: 10.1016/j.pestbp.2015.03.001
EID:

2-s2.0-84930377235
Contributors: Mutunga, J.M.; Anderson, T.D.; Craft, D.T.; Gross, A.D.; Swale, D.R.; Tong, F.; Wong, D.M.; Carlier, P.R.; Bloomquist, J.R.
Source: Self-asserted source
Paul R. Carlier via Scopus - Elsevier

Determination of the active stereoisomer of the MEP pathway-targeting antimalarial agent MMV008138, and initial structure-activity studies

Bioorganic and Medicinal Chemistry Letters
2015 | Journal article
DOI: 10.1016/j.bmcl.2015.02.020
EID:

2-s2.0-84925497752
Contributors: Yao, Z.-K.; Krai, P.M.; Merino, E.F.; Simpson, M.E.; Slebodnick, C.; Cassera, M.B.; Carlier, P.R.
Source: Self-asserted source
Paul R. Carlier via Scopus - Elsevier

Difluoromethyl ketones: Potent inhibitors of wild type and carbamate-insensitive G119S mutant Anopheles gambiae acetylcholinesterase

Bioorganic and Medicinal Chemistry Letters
2015 | Journal article
DOI: 10.1016/j.bmcl.2015.09.019
EID:

2-s2.0-84942823720
Contributors: Camerino, E.; Wong, D.M.; Tong, F.; Körber, F.; Gross, A.D.; Islam, R.; Viayna, E.; Mutunga, J.M.; Li, J.; Totrov, M.M. et al.
Source: Self-asserted source
Paul R. Carlier via Scopus - Elsevier

Inhibiting β-Amyloid-Associated Alzheimer’s Pathogenesis In Vitro and In Vivo by a Multifunctional Dimeric Bis(12)-hupyridone Derived from Its Natural Analogue

Journal of Molecular Neuroscience
2015 | Journal article
DOI: 10.1007/s12031-014-0458-5
EID:

2-s2.0-84925520139
Contributors: Hu, S.; Wang, R.; Cui, W.; Zhang, Z.; Mak, S.; Xu, D.; Choi, C.; Tsim, K.W.; Carlier, P.R.; Lee, M. et al.
Source: Self-asserted source
Paul R. Carlier via Scopus - Elsevier

Mosquitocidal carbamates with low toxicity to agricultural pests: An advantageous property for insecticide resistance management

Pest Management Science
2015 | Journal article
DOI: 10.1002/ps.3899
EID:

2-s2.0-84936203176
Contributors: Swale, D.R.; Carlier, P.R.; Hartsel, J.A.; Ma, M.; Bloomquist, J.R.
Source: Self-asserted source
Paul R. Carlier via Scopus - Elsevier

Structural genomics for drug design against the pathogen Coxiella burnetii

Proteins: Structure, Function and Bioinformatics
2015 | Journal article
DOI: 10.1002/prot.24841
EID:

2-s2.0-84954323212
Contributors: Franklin, M.C.; Cheung, J.; Rudolph, M.J.; Burshteyn, F.; Cassidy, M.; Gary, E.; Hillerich, B.; Yao, Z..-K.; Carlier, P.R.; Totrov, M. et al.
Source: Self-asserted source
Paul R. Carlier via Scopus - Elsevier

Acetylcholinesterase of the sand fly, Phlebotomus papatasi (Scopoli): Construction, expression and biochemical properties of the G119S orthologous mutant

Parasites and Vectors
2014 | Journal article
DOI: 10.1186/s13071-014-0577-4
EID:

2-s2.0-84989186773
Contributors: Temeyer, K.B.; Tong, F.; Totrov, M.M.; Tuckow, A.P.; Chen, Q.-H.; Carlier, P.R.; De León, A.A.P.; Bloomquist, J.R.
Source: Self-asserted source
Paul R. Carlier via Scopus - Elsevier

Antiapicoplast and gametocytocidal screening to identify the mechanisms of action of compounds within the malaria box

Antimicrobial Agents and Chemotherapy
2014 | Journal article
DOI: 10.1128/AAC.01500-13
EID:

2-s2.0-84893487091
Contributors: Bowman, J.D.; Merino, E.F.; Brooks, C.F.; Striepen, B.; Carlier, P.R.; Cassera, M.B.
Source: Self-asserted source
Paul R. Carlier via Scopus - Elsevier

Enantioselective deprotonative ring contraction of N1-Methyl-N4-Boc-benzo[e][1,4]diazepine-2,5-diones

Organic Letters
2014 | Journal article
DOI: 10.1021/ol502586n
EID:

2-s2.0-84907681297
Contributors: Antolak, S.A.; Yao, Z.-K.; Richoux, G.M.; Slebodnick, C.; Carlier, P.R.
Source: Self-asserted source
Paul R. Carlier via Scopus - Elsevier

Voltage-sensitive potassium Kv2 channels as new targets for insecticides

ACS Symposium Series
2014 | Book
DOI: 10.1021/bk-2014-1172.ch006
EID:

2-s2.0-84927131630
Contributors: Bloomquist, J.R.; Mutunga, J.M.; Islam, R.M.; Verma, A.; Ma, M.; Totrov, M.M.; Carlier, P.R.
Source: Self-asserted source
Paul R. Carlier via Scopus - Elsevier

Aryl methylcarbamates: Potency and selectivity towards wild-type and carbamate-insensitive (G119S) Anopheles gambiae acetylcholinesterase, and toxicity to G3 strain An. gambiae

Chemico-Biological Interactions
2013 | Journal article
DOI: 10.1016/j.cbi.2012.09.001
EID:

2-s2.0-84875811566
Contributors: Wong, D.M.; Li, J.; Lam, P.C.H.; Hartsel, J.A.; Mutunga, J.M.; Totrov, M.; Bloomquist, J.R.; Carlier, P.R.
Source: Self-asserted source
Paul R. Carlier via Scopus - Elsevier

Bis(12)-hupyridone, a novel acetylcholinesterase inhibitor, protects against glutamate-induced neuronal excitotoxicity via activating α7 nicotinic acetylcholine receptor/phosphoinositide 3-kinase/Akt cascade

Chemico-Biological Interactions
2013 | Journal article
DOI: 10.1016/j.cbi.2012.10.003
EID:

2-s2.0-84875810025
Contributors: Cui, W.; Hu, S.; Chan, H.H.N.; Luo, J.; Li, W.; Mak, S.; Choi, T.C.; Rong, J.; Carlier, P.R.; Han, Y.
Source: Self-asserted source
Paul R. Carlier via Scopus - Elsevier

Effects of anticholinesterases on catalysis and induced conformational change of the peripheral anionic site of murine acetylcholinesterase

Pesticide Biochemistry and Physiology
2013 | Journal article
DOI: 10.1016/j.pestbp.2013.04.001
EID:

2-s2.0-84879882400
Contributors: Tong, F.; Islam, R.M.; Carlier, P.R.; Ma, M.; Ekström, F.; Bloomquist, J.R.
Source: Self-asserted source
Paul R. Carlier via Scopus - Elsevier

Erratum: Re-engineering aryl methylcarbamates to confer high selectivity for inhibition of Anopheles gambiae versus human acetylcholinesterase (Bioorganic and Medicinal Chemistry Letters (2012) 22 (4593-4598))

Bioorganic and Medicinal Chemistry Letters
2013 | Journal article
DOI: 10.1016/j.bmcl.2013.07.066
EID:

2-s2.0-84884286961
Contributors: Hartsel, J.A.; Wong, D.M.; Mutunga, J.M.; Ma, M.; Anderson, T.D.; Wysinski, A.; Islam, R.; Wong, E.A.; Paulson, S.L.; Li, J. et al.
Source: Self-asserted source
Paul R. Carlier via Scopus - Elsevier

Evaluation of novel carbamate insecticides for neurotoxicity to non-target species

Pesticide Biochemistry and Physiology
2013 | Journal article
DOI: 10.1016/j.pestbp.2013.03.006
EID:

2-s2.0-84879882506
Contributors: Jiang, Y.; Swale, D.; Carlier, P.R.; Hartsel, J.A.; Ma, M.; Ekström, F.; Bloomquist, J.R.
Source: Self-asserted source
Paul R. Carlier via Scopus - Elsevier

Inhibitor profile of bis(n)-tacrines and N-methylcarbamates on acetylcholinesterase from rhipicephalus (boophilus) microplus and phlebotomus papatasi

Pesticide Biochemistry and Physiology
2013 | Journal article
DOI: 10.1016/j.pestbp.2013.03.005
EID:

2-s2.0-84879890947
Contributors: Swale, D.R.; Tong, F.; Temeyer, K.B.; Li, A.; Lam, P.C.-H.; Totrov, M.M.; Carlier, P.R.; Pérez de León, A.A.; Bloomquist, J.R.
Source: Self-asserted source
Paul R. Carlier via Scopus - Elsevier

Neurotoxicology of bis(n)-Tacrines on blattella germanica and Drosophila melanogaster acetylcholinesterase

Archives of Insect Biochemistry and Physiology
2013 | Journal article
DOI: 10.1002/arch.21104
EID:

2-s2.0-84880577630
Contributors: Mutunga, J.M.; Boina, D.R.; Anderson, T.D.; Bloomquist, J.R.; Carlier, P.R.; Wong, D.M.; Lam, P.C.-H.; Totrov, M.M.
Source: Self-asserted source
Paul R. Carlier via Scopus - Elsevier

Stereochemical inversion of a cyano-stabilized grignard reagent: Remarkable effects of the ethereal solvent structure and concentration

Journal of the American Chemical Society
2013 | Journal article
DOI: 10.1021/ja407348s
EID:

2-s2.0-84884845743
Contributors: Gao, M.; Patwardhan, N.N.; Carlier, P.R.
Source: Self-asserted source
Paul R. Carlier via Scopus - Elsevier

Access to "friedel-Crafts-Restricted" tert -alkyl aromatics by activation/methylation of tertiary benzylic alcohols

Journal of Organic Chemistry
2012 | Journal article
DOI: 10.1021/jo202371c
EID:

2-s2.0-84859597604
Contributors: Hartsel, J.A.; Craft, D.T.; Chen, Q.-H.; Ma, M.; Carlier, P.R.
Source: Self-asserted source
Paul R. Carlier via Scopus - Elsevier

Re-engineering aryl methylcarbamates to confer high selectivity for inhibition of Anopheles gambiae versus human acetylcholinesterase

Bioorganic and Medicinal Chemistry Letters
2012 | Journal article
DOI: 10.1016/j.bmcl.2012.05.103
EID:

2-s2.0-84863442518
Contributors: Hartsel, J.A.; Wong, D.M.; Mutunga, J.M.; Ma, M.; Anderson, T.D.; Wysinski, A.; Islam, R.; Wong, E.A.; Paulson, S.L.; Li, J. et al.
Source: Self-asserted source
Paul R. Carlier via Scopus - Elsevier

Select Small Core Structure Carbamates Exhibit High Contact Toxicity to "Carbamate-Resistant" Strain Malaria Mosquitoes, Anopheles gambiae (Akron)

PLoS ONE
2012 | Journal article
DOI: 10.1371/journal.pone.0046712
EID:

2-s2.0-84866997371
Contributors: Wong, D.M.; Li, J.; Chen, Q.-H.; Han, Q.; Mutunga, J.M.; Wysinski, A.; Anderson, T.D.; Ding, H.; Carpenetti, T.L.; Verma, A. et al.
Source: Self-asserted source
Paul R. Carlier via Scopus - Elsevier

Bis(12)-hupyridone, a novel multifunctional dimer, promotes neuronal differentiation more potently than its monomeric natural analog huperzine A possibly through alpha7 nAChR

Brain Research
2011 | Journal article
DOI: 10.1016/j.brainres.2011.05.042
EID:

2-s2.0-79959760304
Contributors: Cui, W.; Cui, G.-Z.; Li, W.; Zhang, Z.; Hu, S.; Mak, S.; Zhang, H.; Carlier, P.R.; Choi, C.-L.; Wong, Y.-T. et al.
Source: Self-asserted source
Paul R. Carlier via Scopus - Elsevier

Incremental solvation precedes ion-pair separation in enantiomerization of a cyano-stabilized Grignard reagent

Chemistry - A European Journal
2011 | Journal article
DOI: 10.1002/chem.201102253
EID:

2-s2.0-80054730101
Contributors: Patwardhan, N.N.; Gao, M.; Carlier, P.R.
Source: Self-asserted source
Paul R. Carlier via Scopus - Elsevier

Neuroprotection against excitotoxic and ischemic insults by bis(12)-hupyridone, a novel anti-acetylcholinesterase dimer, possibly via acting on multiple targets

Brain Research
2011 | Journal article
DOI: 10.1016/j.brainres.2011.09.014
EID:

2-s2.0-80054969251
Contributors: Zhao, Y.; Dou, J.; Luo, J.; Li, W.; Chan, H.H.N.; Cui, W.; Zhang, H.; Han, R.; Carlier, P.R.; Zhang, X. et al.
Source: Self-asserted source
Paul R. Carlier via Scopus - Elsevier

Pd-catalyzed amination as an alternative to nucleophilic aromatic substitution for the synthesis of N-alkyltacrines and analogs

Tetrahedron Letters
2011 | Journal article
DOI: 10.1016/j.tetlet.2010.12.073
EID:

2-s2.0-78751570877
Contributors: Ma, M.; Mehta, J.; Williams, L.D.; Carlier, P.R.
Source: Self-asserted source
Paul R. Carlier via Scopus - Elsevier

Preventing H<inf>2</inf>O<inf>2</inf>-induced apoptosis in cerebellar granule neurons by regulating the VEGFR-2/Akt signaling pathway using a novel dimeric antiacetylcholinesterase bis(12)-hupyridone

Brain Research
2011 | Journal article
DOI: 10.1016/j.brainres.2011.02.006
EID:

2-s2.0-79956272964
Contributors: Cui, W.; Li, W.; Zhao, Y.; Mak, S.; Gao, Y.; Luo, J.; Zhang, H.; Liu, Y.; Carlier, P.R.; Rong, J. et al.
Source: Self-asserted source
Paul R. Carlier via Scopus - Elsevier

Triazole-linked reduced amide isosteres: An approach for the fragment-based drug discovery of anti-Alzheimer's BACE1 inhibitors

Bioorganic and Medicinal Chemistry Letters
2011 | Journal article
DOI: 10.1016/j.bmcl.2011.05.007
EID:

2-s2.0-80955180214
Contributors: Monceaux, C.J.; Hirata-Fukae, C.; Lam, P.C.-H.; Totrov, M.M.; Matsuoka, Y.; Carlier, P.R.
Source: Self-asserted source
Paul R. Carlier via Scopus - Elsevier

Axial-selective H/D exchange of glycine-derived 1 H -benzo[ e ][1,4]diazepin-2(3 H)-ones: Kinetic and computational studies of enantiomerization

Journal of Organic Chemistry
2010 | Journal article
DOI: 10.1021/jo1010608
EID:

2-s2.0-84961978359
Contributors: Carlier, P.R.; Sun, Y.-S.; Hsu, D.C.; Chen, Q.-H.
Source: Self-asserted source
Paul R. Carlier via Scopus - Elsevier

Computational studies of ion-pair separation of benzylic organolithium compounds in THF: Importance of explicit and implicit solvation

Journal of Organic Chemistry
2010 | Journal article
DOI: 10.1021/jo9016452
EID:

2-s2.0-77249160190
Contributors: Deora, N.; Carlier, P.R.
Source: Self-asserted source
Paul R. Carlier via Scopus - Elsevier

Regioselective synthesis of aniline-derived 1,3- And Ci- symmetric 1,4-diols from trans-1,4-cyclohexadiene dioxide

Organic Letters
2010 | Journal article
DOI: 10.1021/ol902856b
EID:

2-s2.0-75749136862
Contributors: Monceaux, C.J.; Carlier, P.R.
Source: Self-asserted source
Paul R. Carlier via Scopus - Elsevier

Self-regeneration of stereocenters (SRS) via stereolabile axially chiral intermediates

Topics in Stereochemistry
2010 | Book
EID:

2-s2.0-77958544763
Contributors: Carlier, P.R.; Hsu, D.C.; Bryson, S.A.
Source: Self-asserted source
Paul R. Carlier via Scopus - Elsevier

Complete mapping of the stereochemical course of retentive deprotonation/alkylation of 1H-benzo[e][1,4]diazepin-2(3H)-ones

Journal of the American Chemical Society
2009 | Journal article
DOI: 10.1021/ja907507j
EID:

2-s2.0-72449178946
Contributors: Hsu, D.C.; Lam, P.C.-H.; Slebodnick, C.; Carlier, P.R.
Source: Self-asserted source
Paul R. Carlier via Scopus - Elsevier

Development and validation of an HPLC-DAD method for bis(12)-hupyridone and its application to a pharmacokinetic study

Journal of Pharmaceutical and Biomedical Analysis
2009 | Journal article
DOI: 10.1016/j.jpba.2008.11.013
EID:

2-s2.0-59049086812
Contributors: Yu, H.; Li, W.M.; Cheung, M.C.; Zuo, Z.; Carlier, P.R.; Gu, Z.M.; Chan, K.; Huang, M.; Wang, Y.T.; Han, Y.F.
Source: Self-asserted source
Paul R. Carlier via Scopus - Elsevier

Inhibition of Blattella germanica acetylcholinesterase by Bis(n)-tacrines: Prospects for the molecular design of a selective insecticide for a household pest

ACS Symposium Series
2009 | Book
DOI: 10.1021/bk-2009-1015.ch004
EID:

2-s2.0-84904809306
Contributors: Mutunga, J.M.; Anderson, T.D.; Wong, D.M.; Carlier, P.R.; Bloomquist, J.R.
Source: Self-asserted source
Paul R. Carlier via Scopus - Elsevier

Pharmacological mapping of the acetylcholinesterase catalytic gorge in mosquitoes with bis(n)-tacrines

ACS Symposium Series
2009 | Book
DOI: 10.1021/bk-2009-1014.ch010
EID:

2-s2.0-84904799507
Contributors: Anderson, T.D.; Paulson, S.L.; Wong, D.M.; Carlier, P.R.; Bloomquist, J.R.
Source: Self-asserted source
Paul R. Carlier via Scopus - Elsevier

Antidepressant-like pharmacological profile of a novel triple reuptake inhibitor, (1S,2S)-3-(Methylamino)-2-(naphthalen-2-yl)-1-phenylpropan-1-ol (PRC200-SS)

Journal of Pharmacology and Experimental Therapeutics
2008 | Journal article
DOI: 10.1124/jpet.108.143610
EID:

2-s2.0-54349103269
Contributors: Liang, Y.; Shaw, A.M.; Boules, M.; Briody, S.; Robinson, J.; Oliveros, A.; Blazar, E.; Williams, K.; Zhang, Y.; Carlier, P.R. et al.
Source: Self-asserted source
Paul R. Carlier via Scopus - Elsevier

Mode of action of the plant-derived silphinenes on insect and mammalian GABAA receptor/chloride channel complex

Pesticide Biochemistry and Physiology
2008 | Journal article
DOI: 10.1016/j.pestbp.2007.12.002
EID:

2-s2.0-41349114373
Contributors: Bloomquist, J.R.; Boina, D.R.; Chow, E.; Carlier, P.R.; Reina, M.; Gonzalez-Coloma, A.
Source: Self-asserted source
Paul R. Carlier via Scopus - Elsevier

The physicochemical properties and the in vivo AChE inhibition of two potential anti-Alzheimer agents, bis(12)-hupyridone and bis(7)-tacrine

Journal of Pharmaceutical and Biomedical Analysis
2008 | Journal article
DOI: 10.1016/j.jpba.2007.08.027
EID:

2-s2.0-36749038771
Contributors: Yu, H.; Li, W.-M.; Kan, K.K.W.; Ho, J.M.K.; Carlier, P.R.; Pang, Y.-P.; Gu, Z.-M.; Zhong, Z.; Chan, K.; Wang, Y.-T. et al.
Source: Self-asserted source
Paul R. Carlier via Scopus - Elsevier

Towards a species-selective acetylcholinesterase inhibitor to control the mosquito vector of malaria, Anopheles gambiae

Chemico-Biological Interactions
2008 | Journal article
DOI: 10.1016/j.cbi.2008.04.037
EID:

2-s2.0-50649083260
Contributors: Carlier, P.R.; Anderson, T.D.; Wong, D.M.; Hsu, D.C.; Hartsel, J.; Ma, M.; Wong, E.A.; Choudhury, R.; Lam, P.C.-H.; Totrov, M.M. et al.
Source: Self-asserted source
Paul R. Carlier via Scopus - Elsevier

Alkylene tether-length dependent γ-aminobutyric acid type A receptor competitive antagonism by tacrine dimers

Neuropharmacology
2007 | Journal article
DOI: 10.1016/j.neuropharm.2006.07.039
EID:

2-s2.0-33846277182
Contributors: Li, C.; Carlier, P.R.; Ren, H.; Kan, K.K.W.; Hui, K.; Wang, H.; Li, W.; Li, Z.; Xiong, K.; Clement, E.C. et al.
Source: Self-asserted source
Paul R. Carlier via Scopus - Elsevier

Antidepressant-like effects of novel triple reuptake inhibitors, PRC025 and PRC050

European Journal of Pharmacology
2007 | Journal article
DOI: 10.1016/j.ejphar.2006.10.004
EID:

2-s2.0-33845804288
Contributors: Shaw, A.M.; Boules, M.; Zhang, Y.; Williams, K.; Robinson, J.; Carlier, P.R.; Richelson, E.
Source: Self-asserted source
Paul R. Carlier via Scopus - Elsevier

East meets west in the search for Alzheimer's therapeutics - Novel dimeric inhibitors from tacrine and huperzine A

Current Alzheimer Research
2007 | Journal article
DOI: 10.2174/156720507781788918
EID:

2-s2.0-34548687019
Contributors: Li, W.M.; Kan, K.K.W.; Carlier, P.R.; Pang, Y.P.; Han, Y.F.
Source: Self-asserted source
Paul R. Carlier via Scopus - Elsevier

Erratum: The first enantioenriched metalated nitrile possessing macroscopic configurational stability: (Organic Letters) (9) 2007 (1319))

Organic Letters
2007 | Journal article
DOI: 10.1021/ol071016y
EID:

2-s2.0-34250667951
Contributors: Carlier, P.R.; Yiqun, Z.
Source: Self-asserted source
Paul R. Carlier via Scopus - Elsevier

The first enantioenriched metalated nitrile possessing macroscopic configurationat stability

Organic Letters
2007 | Journal article
DOI: 10.1021/ol070149g
EID:

2-s2.0-34147107497
Contributors: Carlier, P.R.; Zhang, Y.
Source: Self-asserted source
Paul R. Carlier via Scopus - Elsevier

Complexes of Alkylene-linked tacrine dimers with Torpedo californica acetylcholinesterase: Binding of bis(5)-tacrine produces a dramatic rearrangement in the active-site gorge

Journal of Medicinal Chemistry
2006 | Journal article
DOI: 10.1021/jm060164b
EID:

2-s2.0-33748544640
Contributors: Rydberg, E.H.; Brumshtein, B.; Greenblatt, H.M.; Wong, D.M.; Shaya, D.; Williams, L.D.; Carlier, P.R.; Pang, Y.-P.; Silman, I.; Sussman, J.L.
Source: Self-asserted source
Paul R. Carlier via Scopus - Elsevier
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Peer review (34 reviews for 10 publications/grants)

Review activity for Accounts of chemical research. (1)
Review activity for ACS chemical neuroscience. (3)
Review activity for ACS medicinal chemistry letters. (3)
Review activity for Chemical research in toxicology. (1)
Review activity for ChemMedChem. (1)
Review activity for Journal of agricultural and food chemistry. (1)
Review activity for Journal of medicinal chemistry. (9)
Review activity for Journal of organic chemistry. (6)
Review activity for Journal of the American Chemical Society. (5)
Review activity for Organic letters. (4)
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