Personal information

United Kingdom

Biography

Responsible for delivering PHE’s gonococcal reference service and microbiological lead on the national gonococcal resistance to antimicrobial surveillance programme (GRASP). Also microbiology co-ordinator and PHE project lead for Euro-GASP (European Gonococcal Antimicrobial Surveillance Programme) (August 2009 – present) and formally the microbiology co-ordinator of the ESSTI (European Surveillance of Sexually Transmitted Infections) programme (April 2006 – July 2009).

Other Neisseria gonorrhoeae work includes; microbiological lead for a clinical trial investigating the use of gentamicin in the treatment of gonorrhoea, various private evaluations of antimicrobial compounds against N. gonorrhoeae, transformation and conjugation of resistance determinants, establishment of electroporation for N. gonorrhoeae, molecular epidemiological studies, participation in outbreak and whole genome sequencing studies, investigation of the genetic diversity of TEM alleles and collaborator on the eSTI2 project which is developing point-of-care tests for STIs.

Activities

Employment (4)

Public Health England Colindale: London, London, GB

2006-04-01 to present | Senior Healthcare Scientist (Antimicrobial Resistance and Healthcare Associated Infections Reference Unit)
Employment
Source: Self-asserted source
Michelle Cole

Health Protection Agency: London, London, GB

2002-10 to 2006-04 | Evaluations Microbiologist (Evaluations Unit - Virus Reference Division)
Employment
Source: Self-asserted source
Michelle Cole

Nortel Networks Ltd: Harlow, Essex, GB

1999-04 to 2001-04 | Project manager
Employment
Source: Self-asserted source
Michelle Cole

Saint Mary's Hospital: London, London, GB

1996-12 to 1999-04 | Research Assistant (Medical Microbiology)
Employment
Source: Self-asserted source
Michelle Cole

Education and qualifications (3)

University of Portsmouth: Portsmouth, Hampshire, GB

2009-10 to 2015-12 | Doctor of Biomedical Science
Education
Source: Self-asserted source
Michelle Cole

Cranfield University: Cranfield, Central Bedfordshire, GB

2003-10 to 2005-08 | M.Sc. Medical Diagnostics
Education
Source: Self-asserted source
Michelle Cole

Imperial College London: London, London, GB

1993-08 to 1996-06 | BSc (Hons) Biology with Microbiology
Education
Source: Self-asserted source
Michelle Cole

Funding (4)

European Gonococcal Antimicrobial Surveillance Programme

2017-08 to 2021-07 | Award
European Centre for Disease Prevention and Control (Stockholm, SE)
GRANT_NUMBER:

ECDC/2017/004

Source: Self-asserted source
Michelle Cole

LGV Enhanced Surveillance pilot

2016-07 to 2017-04 | Contract
European Centre for Disease Prevention and Control (Stockholm, SE)
GRANT_NUMBER:

ECD.6300

Source: Self-asserted source
Michelle Cole

A randomised controlled trial to compare the clinical effectiveness and safety of gentamicin and ceftriaxone in the treatment of gonorrhoea

2015-04 to 2017-12 | Grant
National Institute for Health Research (London, GB)
GRANT_NUMBER:

HTA-12/127/10

Source: Self-asserted source
Michelle Cole

European Gonococcal Antimicrobial Surveillance Programme

2013-06 to 2017-07 | Contract
European Centre for Disease Prevention and Control (Stockholm, SE)
GRANT_NUMBER:

ECDC/2013/015

Source: Self-asserted source
Michelle Cole

Works (50 of 99)

Items per page:
Page 1 of 2

Antibody correlates of protection against Delta infection after vaccination: A nested case-control within the UK-based SIREN study.

The Journal of infection
2023-09 | Journal article
Contributors: Atti A; Insalata F; Carr EJ; Otter AD; Foulkes S; Wu MY; Crick COVID Immunity Pipeline; Cole MJ; Linley E; Semper A et al.
Source: Self-asserted source
Michelle Cole via Europe PubMed Central

Genomic epidemiology of syphilis in England: a population-based study.

The Lancet. Microbe
2023-09 | Journal article
Contributors: Beale MA; Thorn L; Cole MJ; Pitt R; Charles H; Ewens M; French P; Guiver M; Page EE; Smit E et al.
Source: Self-asserted source
Michelle Cole via Europe PubMed Central

Projecting the development of antimicrobial resistance in Neisseria gonorrhoeae from antimicrobial surveillance data: a mathematical modelling study.

BMC infectious diseases
2023-04 | Journal article
Contributors: Riou J; Althaus CL; Allen H; Cole MJ; Grad YH; Heijne JCM; Unemo M; Low N
Source: Self-asserted source
Michelle Cole via Europe PubMed Central

Early Warning Surveillance for SARS-CoV-2 Omicron Variants, United Kingdom, November 2021-September 2022.

Emerging infectious diseases
2022-12 | Journal article
Contributors: Foulkes S; Monk EJM; Sparkes D; Hettiarachchi N; Milligan ID; Munro K; Taylor-Kerr A; Platt N; Howells A; Kyaw JYA et al.
Source: Self-asserted source
Michelle Cole via Europe PubMed Central

Antimicrobial-resistant gonorrhoea: the national public health response, England, 2013 to 2020.

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
2022-10 | Journal article
Contributors: Merrick R; Cole M; Pitt R; Enayat Q; Ivanov Z; Day M; Sun S; Sinka K; Woodford N; Mohammed H et al.
Source: Self-asserted source
Michelle Cole via Europe PubMed Central

Challenges of <i>in vitro</i> propagation and antimicrobial susceptibility testing of <i>Mycoplasma genitalium</i>

Journal of Antimicrobial Chemotherapy
2022-10-28 | Journal article | Author
Part of ISSN: 0305-7453
Part of ISSN: 1460-2091
Contributors: Rachel Pitt; Dolcibella Boampong; Michaela Day; Jensen JS; Michelle Cole
Source: Self-asserted source
Michelle Cole

Antibody correlates of protection from SARS-CoV-2 reinfection prior to vaccination: A nested case-control within the SIREN study.

The Journal of infection
2022-09 | Journal article
Contributors: Atti A; Insalata F; Carr EJ; Otter AD; Castillo-Olivares J; Wu M; Harvey R; Howell M; Chan A; Lyall J et al.
Source: Self-asserted source
Michelle Cole via Europe PubMed Central

Burden of SARS-CoV-2 infection in healthcare workers during second wave in England and impact of vaccines: prospective multicentre cohort study (SIREN) and mathematical model.

BMJ (Clinical research ed.)
2022-07 | Journal article
Contributors: Pople D; Monk EJM; Evans S; Foulkes S; Islam J; Wellington E; Atti A; Hope R; Robotham J; Hopkins S et al.
Source: Self-asserted source
Michelle Cole via Europe PubMed Central

Impact of prior SARS-CoV-2 infection and COVID-19 vaccination on the subsequent incidence of COVID-19: a multicentre prospective cohort study among UK healthcare workers - the SIREN (Sarscov2 Immunity & REinfection EvaluatioN) study protocol.

BMJ open
2022-06 | Journal article
Contributors: Wallace S; Hall V; Charlett A; Kirwan PD; Cole M; Gillson N; Atti A; Timeyin J; Foulkes S; Taylor-Kerr A et al.
Source: Self-asserted source
Michelle Cole via Europe PubMed Central

Significant increase in azithromycin "resistance" and susceptibility to ceftriaxone and cefixime in Neisseria gonorrhoeae isolates in 26 European countries, 2019.

BMC infectious diseases
2022-06 | Journal article
Contributors: Day MJ; Jacobsson S; Spiteri G; Kulishev C; Sajedi N; Woodford N; Blumel B; van der Werf MJ; Amato-Gauci AJ; Unemo M et al.
Source: Self-asserted source
Michelle Cole via Europe PubMed Central

Europe-wide expansion and eradication of multidrug-resistant Neisseria gonorrhoeae lineages: a genomic surveillance study.

The Lancet. Microbe
2022-05 | Journal article
Contributors: Sánchez-Busó L; Cole MJ; Spiteri G; Day M; Jacobsson S; Golparian D; Sajedi N; Yeats CA; Abudahab K; Underwood A et al.
Source: Self-asserted source
Michelle Cole via Europe PubMed Central

The European response to control and manage multi- and extensively drug-resistant <i>Neisseria gonorrhoeae</i>.

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
2022-05 | Journal article
Contributors: Cole MJ; Day M; Jacobsson S; Amato-Gauci AJ; Spiteri G; Unemo M; the European Gonorrhoea Response Plan Group; European Gonorrhoea Response Plan Group
Source: Self-asserted source
Michelle Cole via Europe PubMed Central

Is there an association between previous infection with Neisseria gonorrhoeae and gonococcal AMR? A cross-sectional analysis of national and sentinel surveillance data in England, 2015-2019.

Sexually transmitted infections
2022-03 | Journal article
Contributors: Allen H; Merrick R; Ivanov Z; Pitt R; Mohammed H; Sinka K; Hughes G; Fifer H; Cole MJ
Source: Self-asserted source
Michelle Cole via Europe PubMed Central

Whole-genome sequencing of <i>Chlamydia trachomatis</i> isolates from persistently infected patients.

International journal of STD & AIDS
2022-03 | Journal article
Contributors: Pitt R; Doyle R; Theilgaard Christiansen M; Horner P; Hathorn E; Alexander S; Woodford N; Cole M; Breuer J
Source: Self-asserted source
Michelle Cole via Europe PubMed Central

Protection against SARS-CoV-2 after Covid-19 Vaccination and Previous Infection.

The New England journal of medicine
2022-02 | Journal article
Contributors: Hall V; Foulkes S; Insalata F; Kirwan P; Saei A; Atti A; Wellington E; Khawam J; Munro K; Cole M et al.
Source: Self-asserted source
Michelle Cole via Europe PubMed Central

Effectiveness and durability of protection against future SARS-CoV-2 infection conferred by COVID-19 vaccination and previous infection; findings from the UK SIREN prospective cohort study of healthcare workers March 2020 to September 2021

2021-12 | Preprint
Contributors: Hall V; Foulkes S; Insalata F; Saei A; Kirwan P; Atti A; Wellington E; Khawam J; Munro K; Cole M et al.
Source: Self-asserted source
Michelle Cole via Europe PubMed Central

Use of genomics to investigate Neisseria gonorrhoeae antimicrobial susceptibility testing discrepancies.

The Journal of antimicrobial chemotherapy
2021-12 | Journal article
Contributors: Fifer H; Schaefer U; Pitt R; Allen H; Day M; Woodford N; Cole MJ
Source: Self-asserted source
Michelle Cole via Europe PubMed Central

Global phylogeny of Treponema pallidum lineages reveals recent expansion and spread of contemporary syphilis.

Nature microbiology
2021-11 | Journal article
Contributors: Beale MA; Marks M; Cole MJ; Lee MK; Pitt R; Ruis C; Balla E; Crucitti T; Ewens M; Fernández-Naval C et al.
Source: Self-asserted source
Michelle Cole via Europe PubMed Central

Rapid Increase in Lymphogranuloma Venereum among HIV-Negative Men Who Have Sex with Men, England, 2019.

Emerging infectious diseases
2021-10 | Journal article
Contributors: Prochazka M; Charles H; Allen H; Cole M; Hughes G; Sinka K
Source: Self-asserted source
Michelle Cole via Europe PubMed Central

No widespread dissemination of <i>Chlamydia trachomatis</i> diagnostic-escape variants and the impact of <i>Neisseria gonorrhoeae</i> positivity on the Aptima Combo 2 assay.

Sexually transmitted infections
2021-09 | Journal article
Contributors: Cole MJ; Davis GS; Fifer H; Saunders JM; Unemo M; Hadad R; Roberts DJ; Fazal M; Day MJ; Minshull J et al.
Source: Self-asserted source
Michelle Cole via Europe PubMed Central

Serological profile of first SARS-CoV-2 reinfection cases detected within the SIREN study.

The Journal of infection
2021-09 | Journal article
Contributors: Atti A; Ferrari M; Castillo-Olivares J; Monk EJM; Gopal R; Patel M; Hoschler K; Cole MJ; Semper A; Hewson J et al.
Source: Self-asserted source
Michelle Cole via Europe PubMed Central

Detection of markers predictive of macrolide and fluoroquinolone resistance in <i>Mycoplasma genitalium</i> from patients attending sexual health services.

Sexually transmitted infections
2021-06 | Journal article
Contributors: Day MJ; Cole MJ; Fifer H; Woodford N; Pitt R
Source: Self-asserted source
Michelle Cole via Europe PubMed Central

Frequency and correlates of Mycoplasma genitalium antimicrobial resistance mutations and their association with treatment outcomes: findings from a national sentinel surveillance pilot in England.

Sexually transmitted diseases
2021-06 | Journal article
Contributors: Fifer H; Merrick R; Pitt R; Yung M; Allen H; Day M; Sinka K; Woodford N; Mohammed H; Brown CS et al.
Source: Self-asserted source
Michelle Cole via Europe PubMed Central

A community-driven resource for genomic epidemiology and antimicrobial resistance prediction of Neisseria gonorrhoeae at Pathogenwatch.

Genome medicine
2021-04 | Journal article
Contributors: Sánchez-Busó L; Yeats CA; Taylor B; Goater RJ; Underwood A; Abudahab K; Argimón S; Ma KC; Mortimer TD; Golparian D et al.
Source: Self-asserted source
Michelle Cole via Europe PubMed Central

COVID-19 vaccine coverage in health-care workers in England and effectiveness of BNT162b2 mRNA vaccine against infection (SIREN): a prospective, multicentre, cohort study.

Lancet (London, England)
2021-04 | Journal article
Contributors: Hall VJ; Foulkes S; Saei A; Andrews N; Oguti B; Charlett A; Wellington E; Stowe J; Gillson N; Atti A et al.
Source: Self-asserted source
Michelle Cole via Europe PubMed Central

SARS-CoV-2 infection rates of antibody-positive compared with antibody-negative health-care workers in England: a large, multicentre, prospective cohort study (SIREN).

Lancet (London, England)
2021-04 | Journal article
Contributors: Hall VJ; Foulkes S; Charlett A; Atti A; Monk EJM; Simmons R; Wellington E; Cole MJ; Saei A; Oguti B et al.
Source: Self-asserted source
Michelle Cole via Europe PubMed Central

Associations between antimicrobial susceptibility/resistance of Neisseria gonorrhoeae isolates in European Union/European Economic Area and patients' gender, sexual orientation and anatomical site of infection, 2009-2016.

BMC infectious diseases
2021-03 | Journal article
Contributors: Jacobsson S; Cole MJ; Spiteri G; Day M; Unemo M; Euro-GASP Network
Source: Self-asserted source
Michelle Cole via Europe PubMed Central

High susceptibility to zoliflodacin and conserved target (GyrB) for zoliflodacin among 1209 consecutive clinical Neisseria gonorrhoeae isolates from 25 European countries, 2018.

The Journal of antimicrobial chemotherapy
2021-02 | Journal article
Contributors: Unemo M; Ahlstrand J; Sánchez-Busó L; Day M; Aanensen D; Golparian D; Jacobsson S; Cole MJ; Torreblanca RA; Ásmundsdóttir LR et al.
Source: Self-asserted source
Michelle Cole via Europe PubMed Central

Evaluation of the SpeeDx ResistancePlus® GC and SpeeDx GC 23S 2611 (beta) molecular assays for prediction of antimicrobial resistance/susceptibility to ciprofloxacin and azithromycin in Neisseria gonorrhoeae.

The Journal of antimicrobial chemotherapy
2021-01 | Journal article
Contributors: Hadad R; Cole MJ; Ebeyan S; Jacobsson S; Tan LY; Golparian D; Erskine S; Day M; Whiley D; Unemo M et al.
Source: Self-asserted source
Michelle Cole via Europe PubMed Central

Neisseria gonorrhoeae Sequence Typing for Antimicrobial Resistance (NG-STAR) clonal complexes are consistent with genomic phylogeny and provide simple nomenclature, rapid visualization and antimicrobial resistance (AMR) lineage predictions.

The Journal of antimicrobial chemotherapy
2021-01 | Journal article
Contributors: Golparian D; Sánchez-Busó L; Cole M; Unemo M
Source: Self-asserted source
Michelle Cole via Europe PubMed Central

What's left in the cupboard? Older antimicrobials for treating gonorrhoea.

The Journal of antimicrobial chemotherapy
2021-01 | Journal article
Contributors: Fifer H; Livermore DM; Uthayakumaran T; Woodford N; Cole MJ
Source: Self-asserted source
Michelle Cole via Europe PubMed Central

Prevalence of Chlamydia trachomatis and Mycoplasma genitalium coinfections and M. genitalium antimicrobial resistance in rectal specimens.

Sexually transmitted infections
2020-10 | Journal article
Contributors: Pitt R; Fifer H; Woodford N; Hopkins S; Cole MJ
Source: Self-asserted source
Michelle Cole via Europe PubMed Central

Investigating the decline in Lymphogranuloma venereum diagnoses in men who have sex with men in the United Kingdom since 2016: an analysis of surveillance data.

Sexual health
2020-08 | Journal article
Contributors: Allen H; Pitt R; Bardsley M; Smolarchuk C; Sullivan A; Mohammed H; Cole M; Fifer H; Wallace L; Thomas D et al.
Source: Self-asserted source
Michelle Cole via Europe PubMed Central

Sensitivity, specificity, inclusivity and exclusivity of the updated Aptima Combo 2 assay, which provides detection coverage of the new diagnostic-escape Chlamydia trachomatis variants.

BMC infectious diseases
2020-06 | Journal article
Contributors: Unemo M; Hansen M; Hadad R; Puolakkainen M; Westh H; Rantakokko-Jalava K; Thilesen C; Cole MJ; Boiko I; Lan PT et al.
Source: Self-asserted source
Michelle Cole via Europe PubMed Central

Genomic and Phenotypic Variability in Neisseria gonorrhoeae Antimicrobial Susceptibility, England.

Emerging infectious diseases
2020-03 | Journal article
Contributors: Town K; Harris S; Sánchez-Busó L; Cole MJ; Pitt R; Fifer H; Mohammed H; Field N; Hughes G
Source: Self-asserted source
Michelle Cole via Europe PubMed Central

Antimicrobial resistance in Neisseria gonorrhoeae isolates from foreign-born population in the European Gonococcal Antimicrobial Surveillance Programme.

Sexually transmitted infections
2020-02 | Journal article
Contributors: Hernando Rovirola C; Spiteri G; Sabidó M; Montoliu A; Gonzalez V; Casabona J; Cole MJ; Noori T; Unemo M
Source: Self-asserted source
Michelle Cole via Europe PubMed Central

Gentamicin, azithromycin and ceftriaxone in the treatment of gonorrhoea: the relationship between antibiotic MIC and clinical outcome.

The Journal of antimicrobial chemotherapy
2020-02 | Journal article
Contributors: Cole MJ; Tan W; Fifer H; Brittain C; Duley L; Hepburn T; Lawrence T; Montgomery AA; Sprange K; Thandi S et al.
Source: Self-asserted source
Michelle Cole via Europe PubMed Central

Antimicrobial resistance in Mycoplasma genitalium sampled from the British general population.

Sexually transmitted infections
2020-01 | Journal article
Contributors: Pitt R; Unemo M; Sonnenberg P; Alexander S; Beddows S; Cole MJ; Clifton S; Mercer CH; Johnson AM; Ison CA et al.
Source: Self-asserted source
Michelle Cole via Europe PubMed Central

Phylogenomic analysis of Neisseria gonorrhoeae transmission to assess sexual mixing and HIV transmission risk in England: a cross-sectional, observational, whole-genome sequencing study.

The Lancet. Infectious diseases
2020-01 | Journal article
Contributors: Town K; Field N; Harris SR; Sánchez-Busó L; Cole MJ; Pitt R; Fifer H; Mohammed H; Hughes G
Source: Self-asserted source
Michelle Cole via Europe PubMed Central

The European gonococcal antimicrobial surveillance programme (Euro-GASP) appropriately reflects the antimicrobial resistance situation for Neisseria gonorrhoeae in the European Union/European Economic Area.

BMC infectious diseases
2019-12 | Journal article
Contributors: Cole MJ; Quinten C; Jacobsson S; Day M; Amato-Gauci AJ; Woodford N; Spiteri G; Unemo M; Euro-GASP network
Source: Self-asserted source
Michelle Cole via Europe PubMed Central

Prevalence of new variants of Chlamydia trachomatis escaping detection by the Aptima Combo 2 assay, England, June to August 2019.

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
2019-09 | Journal article
Contributors: Roberts DJ; Davis GS; Cole MJ; Naik D; Maru H; Woodford N; Muir P; Horner P; Simms I; Thickett G et al.
Source: Self-asserted source
Michelle Cole via Europe PubMed Central

World Health Organization Global Gonococcal Antimicrobial Surveillance Program (WHO GASP): review of new data and evidence to inform international collaborative actions and research efforts.

Sexual health
2019-08 | Journal article
Contributors: Unemo M; Lahra MM; Cole M; Galarza P; Ndowa F; Martin I; Dillon JR; Ramon-Pardo P; Bolan G; Wi T
Source: Self-asserted source
Michelle Cole via Europe PubMed Central

Detection of tet(M) in high-level tetracycline-resistant Neisseria gonorrhoeae.

The Journal of antimicrobial chemotherapy
2019-07 | Journal article
Contributors: Pitt R; Sadouki Z; Town K; Fifer H; Mohammed H; Hughes G; Woodford N; Cole MJ
Source: Self-asserted source
Michelle Cole via Europe PubMed Central

Letter to the editor: Chlamydia trachomatis samples testing falsely negative in the Aptima Combo 2 test in Finland, 2019.

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
2019-06 | Journal article
Contributors: Unemo M; Getman D; Hadad R; Cole M; Thomson N; Puolakkainen M; Spiteri G
Source: Self-asserted source
Michelle Cole via Europe PubMed Central

Substantial underdiagnosis of lymphogranuloma venereum in men who have sex with men in Europe: preliminary findings from a multicentre surveillance pilot.

Sexually transmitted infections
2019-06 | Journal article
Contributors: Cole MJ; Field N; Pitt R; Amato-Gauci AJ; Begovac J; French PD; Keše D; Klavs I; Zidovec Lepej S; Pöcher K et al.
Source: Self-asserted source
Michelle Cole via Europe PubMed Central

Gentamicin as an alternative to ceftriaxone in the treatment of gonorrhoea: the G-TOG non-inferiority RCT.

Health technology assessment (Winchester, England)
2019-05 | Book
Contributors: Ross JD; Harding J; Duley L; Montgomery AA; Hepburn T; Tan W; Brittain C; Meakin G; Sprange K; Thandi S et al.
Source: Self-asserted source
Michelle Cole via Europe PubMed Central

Gentamicin compared with ceftriaxone for the treatment of gonorrhoea (G-ToG): a randomised non-inferiority trial.

Lancet (London, England)
2019-05 | Journal article
Contributors: Ross JDC; Brittain C; Cole M; Dewsnap C; Harding J; Hepburn T; Jackson L; Keogh M; Lawrence T; Montgomery AA et al.
Source: Self-asserted source
Michelle Cole via Europe PubMed Central

Population-level antimicrobial consumption is associated with decreased antimicrobial susceptibility in Neisseria gonorrhoeae in 24 European countries: an ecological analysis.

The Journal of infectious diseases
2019-04 | Journal article
Contributors: Kenyon C; Buyze J; Spiteri G; Cole MJ; Unemo M
Source: Self-asserted source
Michelle Cole via Europe PubMed Central

Detection in the United Kingdom of the Neisseria gonorrhoeae FC428 clone, with ceftriaxone resistance and intermediate resistance to azithromycin, October to December 2018.

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
2019-03 | Journal article
Contributors: Eyre DW; Town K; Street T; Barker L; Sanderson N; Cole MJ; Mohammed H; Pitt R; Gobin M; Irish C et al.
Source: Self-asserted source
Michelle Cole via Europe PubMed Central

Ten years of external quality assessment (EQA) of Neisseria gonorrhoeae antimicrobial susceptibility testing in Europe elucidate high reliability of data.

BMC infectious diseases
2019-03 | Journal article
Contributors: Cole MJ; Quaye N; Jacobsson S; Day M; Fagan E; Ison C; Pitt R; Seaton S; Woodford N; Stary A et al.
Source: Self-asserted source
Michelle Cole via Europe PubMed Central
Items per page:
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