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ResearcherID: G-3678-2011
Scopus Author ID: 24336112300

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Employment (15)

Karlstads Universitet: Karlstad, Värmalnd, SE

2020-09-01 to present | Senior Lecturer in Chemistry (Lektor i Kemi) (Department of Engineering and Chemical Sciences)
Employment
Source: Self-asserted source
Patricia Saenz-Méndez

Universidad de la República Uruguay: Montevideo, Montevideo, UY

2016-12-19 to present | Associate Professor of Computational Chemistry (DETEMA)
Employment
Source: Self-asserted source
Patricia Saenz-Méndez

KTH (Royal Institute of Technology): Stockholm, Stockholm, SE

2018-10-01 to 2020-07-31 | Researcher (Department of Fibre and Polymer Technology)
Employment
Source: Self-asserted source
Patricia Saenz-Méndez

Göteborgs Universitet: Goteborg, SE

2015-10-01 to 2016-09-30 | MoRE fellow - FP7-PEOPLE - Västra Götaland Regionen (Department of Chemistry and Molecular Biology)
Employment
Source: Self-asserted source
Patricia Saenz-Méndez

Universidad de la República Uruguay: Montevideo, Montevideo, UY

2014-03 to 2015-09 | Assistant Professor of Computational Chemistry (DETEMA)
Employment
Source: Self-asserted source
Patricia Saenz-Méndez

Universidad de la República Uruguay: Montevideo, Montevideo, UY

2008-11 to 2014-03 | Assistant Professor of Physical Organic Chemistry (DETEMA)
Employment
Source: Self-asserted source
Patricia Saenz-Méndez

Göteborgs Universitet: Goteborg, SE

2013-01 to 2013-03 | Postdoctoral Research Scientist (Department of Chemistry and Molecular Biology)
Employment
Source: Self-asserted source
Patricia Saenz-Méndez

National University of Ireland - Galway: Galway, Galway, IE

2010-04 to 2010-07 | Postdoc - Researcher (School of Chemistry, Biophysical and Theoretical Chemistry Group)
Employment
Source: Self-asserted source
Patricia Saenz-Méndez

Örebro University Örebro Life Science Center: Orebro, SE

2007-01 to 2007-12 | Postdoctoral Fellow (Department of Natural Sciences)
Employment
Source: Self-asserted source
Patricia Saenz-Méndez

Universidad de la República Uruguay: Montevideo, Montevideo, UY

2002-09 to 2006-10 | PhD Student (DETEMA - DQO)
Employment
Source: Self-asserted source
Patricia Saenz-Méndez

University of Iowa: Iowa City, IA, US

2005-06 to 2005-08 | Visiting PhD Student (College of Pharmacy. Division of Medicinal and Natural Products Chemistry)
Employment
Source: Self-asserted source
Patricia Saenz-Méndez

Universidad de la República Uruguay: Montevideo, Montevideo, UY

1998-11 to 2000-11 | Master Student (DQO)
Employment
Source: Self-asserted source
Patricia Saenz-Méndez

Universidad de Buenos Aires: Buenos Aires, AR

2000-08 to 2000-08 | Visiting Student (Center of synthesis and study of new antineoplastic compounds)
Employment
Source: Self-asserted source
Patricia Saenz-Méndez

Consejo Superior de Investigaciones Científicas: Madrid, Madrid, ES

1999-01 to 1999-03 | Visiting Student (Medicinal Chemistry Institute)
Employment
Source: Self-asserted source
Patricia Saenz-Méndez

Universidad de la República Uruguay: Montevideo, Montevideo, UY

1995-09 to 1998-02 | Undergraduate Research Assistant (DQO)
Employment
Source: Self-asserted source
Patricia Saenz-Méndez

Education and qualifications (4)

Universidad de la República Uruguay: Montevideo, Montevideo, UY

2002-09 to 2006-10 | Doctor in Chemistry (specialization in Organic Synthesis and Computational Chemistry) (DETEMA - DQO)
Education
Source: Self-asserted source
Patricia Saenz-Méndez

Universidad de la República Uruguay: Montevideo, Montevideo, UY

1998-11 to 2000-11 | Master in Science (specialization in Organic Synthesis and Medicinal Chemistry) (Organic Chemistry Department (DQO))
Education
Source: Self-asserted source
Patricia Saenz-Méndez

Universidad de la República Uruguay: Montevideo, Montevideo, UY

1996-03 to 1999-10 | Pharmaceutical Chemist
Education
Source: Self-asserted source
Patricia Saenz-Méndez

Universidad de la República Uruguay: Montevideo, Montevideo, UY

1991-03 to 1996-12 | Bachelor in Chemistry
Education
Source: Self-asserted source
Patricia Saenz-Méndez

Works (38)

Structural Insights into Pseudomonas aeruginosa Exotoxin A–Elongation Factor 2 Interactions: A Molecular Dynamics Study

Journal of Chemical Information and Modeling
2023-03-13 | Journal article
DOI: 10.1021/acs.jcim.3c00064
Contributors: Asma Gholami; Dariush Minai-Tehrani; Sayyed Jalil Mahdizadeh; Patricia Saenz-Mendez; Leif A. Eriksson
Source: check_circle
Crossref

Conformational Selection in Biocatalytic Plastic Degradation by PETase

ACS Catalysis
2022-03-18 | Journal article
DOI: 10.1021/acscatal.1c05548
Contributors: Boyang Guo; Sudarsana Reddy Vanga; Ximena Lopez-Lorenzo; Patricia Saenz-Mendez; Sara Rönnblad Ericsson; Yuan Fang; Xinchen Ye; Karen Schriever; Eva Bäckström; Antonino Biundo et al.
Source: check_circle
Crossref

Engineering of Ancestors as a Tool to Elucidate Structure, Mechanism, and Specificity of Extant Terpene Cyclase

Journal of the American Chemical Society
2021-03-17 | Journal article
DOI: 10.1021/jacs.0c10214
Contributors: Karen Schriever; Patricia Saenz-Mendez; Reshma Srilakshmi Rudraraju; Natalie M. Hendrikse; Elton P. Hudson; Antonino Biundo; Robert Schnell; Per-Olof Syrén
Source: check_circle
Crossref

Enzymatic synthesis of non-natural trisaccharides and galactosides; Insights of their interaction with galectins as a function of their structure

Carbohydrate Research
2019-01 | Journal article
DOI: 10.1016/j.carres.2018.10.011
Contributors: Cecilia Porciúncula González; Alejandro J. Cagnoni; Karina V. Mariño; Carolina Fontana; Patricia Saenz-Méndez; Gabriela Irazoqui; Cecilia Giacomini
Source: check_circle
Crossref

QM/MM Studies of Dph5 – A Promiscuous Methyltransferase in the Eukaryotic Biosynthetic Pathway of Diphthamide

Journal of Chemical Information and Modeling
2018-07-23 | Journal article
DOI: 10.1021/acs.jcim.8b00217
Contributors: Johanna Hörberg; Patricia Saenz-Mendez; Leif A. Eriksson
Source: check_circle
Crossref

Homology model of the human tRNA splicing ligase RtcB

Proteins: Structure, Function, and Bioinformatics
2017-11 | Journal article
DOI: 10.1002/prot.25352
Contributors: Argha Nandy; Patricia Saenz‐Méndez; Adrienne M. Gorman; Afshin Samali; Leif A. Eriksson
Source: check_circle
Crossref

Using density functional theory to increase the accuracy of experimental crystal structures: The case of potassium peroxocarbonate

Journal of Molecular Structure
2017-10 | Journal article
DOI: 10.1016/j.molstruc.2017.05.115
Contributors: Ricardo Faccio; Patricia Saenz-Méndez; Martina Kieninger; Oscar N. Ventura
Source: check_circle
Crossref

Structural insights into human microsomal epoxide hydrolase by combined homology modeling, molecular dynamics simulations, and molecular docking calculations

Proteins: Structure, Function, and Bioinformatics
2017-04 | Journal article
DOI: 10.1002/prot.25251
Contributors: Patricia Saenz‐Méndez; Aline Katz; María Lucía Pérez‐Kempner; Oscar N. Ventura; Marta Vázquez
Source: check_circle
Crossref

Ligand Selectivity between the ADP-Ribosylating Toxins: An Inverse-Docking Study for Multitarget Drug Discovery

ACS Omega
2017-04-30 | Journal article
DOI: 10.1021/acsomega.7b00010
Contributors: Patricia Saenz-Méndez; Martin Eriksson; Leif A. Eriksson
Source: check_circle
Crossref

Towards Celiac-safe foods: Decreasing the affinity of transglutaminase 2 for gliadin by addition of ascorbyl palmitate and ZnCl2 as detoxifiers

2017-03-06 | Journal article
DOI: 10.1038/s41598-017-00174-z
Source: Self-asserted source
Patricia Saenz-Méndez

Structures, Properties, and Dynamics of Intermediates in eEF2-Diphthamide Biosynthesis

Journal of Chemical Information and Modeling
2016 | Journal article
DOI: 10.1021/acs.jcim.6b00223
EID:

2-s2.0-84988815585
Contributors: Billod, J.-M.; Saenz-Mendez, P.; Blomberg, A.; Eriksson, L.A.
Source: Self-asserted source
Patricia Saenz-Méndez via Scopus - Elsevier

Improved Homology Model of the Human all-trans Retinoic Acid Metabolizing Enzyme CYP26A1

Molecules
2016-03-15 | Journal article
DOI: 10.3390/molecules21030351
Contributors: Mohamed Awadalla; Thamir Alshammari; Leif Eriksson; Patricia Saenz-Méndez
Source: check_circle
Crossref
grade
Preferred source (of 3)‎

Computational Study of the Initial Step in the Mechanism of Dehaloperoxidase A: Determination of the Protonation Scheme at the Active Site and the Movement of the His55 Residue

Quantum Modeling of Complex Molecular Systems
2015 | Book chapter
SOURCE-WORK-ID:

0411161832472-35
Contributors: Bottinelli, Fiorentina; Saenz-Méndez, Patricia; Ventura, Oscar N.
Source: Self-asserted source
Patricia Saenz-Méndez via ResearcherID

Improved homology model of cyclohexanone monooxygenase from Acinetobacter calcoaceticus based on multiple templates

Computational Biology and Chemistry
2014 | Journal article
DOI: http://dx.doi.org/10.1016/j.compbiolchem.2014.01.012
Part of ISSN: 1476-9271
Contributors: Bermúdez, Eduardo; Ventura, Oscar N.; Eriksson, Leif A.; Saenz-Méndez, Patricia
Source: Self-asserted source
Patricia Saenz-Méndez via ResearcherID

Cloning and Functional Studies of a Splice Variant of CYP26B1 Expressed in Vascular Cells

PLoS ONE
2012 | Journal article
DOI: 10.1371/journal.pone.0036839
Contributors: Elmabsout, Ali Ateia; Kumawat, Ashok; Saenz-Méndez, Patricia; Krivospitskaya, Olesya; Sävenstrand, Helena; Olofsson, Peder S.; Eriksson, Leif A.; Strid, Åke; Valen, Guro; Törmä, Hans et al.
Source: Self-asserted source
Patricia Saenz-Méndez via ResearcherID
grade
Preferred source (of 2)‎

COMPARE analysis of the toxicity of an iminoquinone derivative of the imidazo[5,4-f]benzimidazoles with NAD(P)H:quinone oxidoreductase 1 (NQO1) activity and computational docking of quinones as NQO1 substrates

Bioorganic & medicinal chemistry
2012 | Journal article
DOI: 10.1016/j.bmc.2012.03.063
Contributors: Fagan, Vincent; Bonham, Sarah; Carty, Michael P.; Saenz-Mendez, Patricia; Eriksson, Leif A.; Aldabbagh, Fawaz
Source: Self-asserted source
Patricia Saenz-Méndez via ResearcherID
grade
Preferred source (of 2)‎

Experimental and Theoretical Study of the Movement of the Wpd Flexible Loop of Human Protein Tyrosine Phosphatase Ptp1B in Complex With Halide Ions

Biophysical Reviews and Letters
2012 | Journal article
DOI: 10.1142/S1793048012500087
Contributors: Katz, Aline; Saenz-Méndez, Patricia; Cousido-Siah, Alexandra; Podjarny, Alberto D.; Ventura, Oscar N.
Source: Self-asserted source
Patricia Saenz-Méndez via ResearcherID
grade
Preferred source (of 2)‎

Homology models of human all-trans retinoic acid metabolizing enzymes CYP26B1 and CYP26B1 spliced variant

Journal of chemical information and modeling
2012 | Journal article
DOI: 10.1021/ci300264u
Contributors: Saenz-Méndez, Patricia; Elmabsout, Ali Ateia; Sävenstrand, Helena; Awadalla, Mohamed Khalid Alhaj; Strid, Åke; Sirsjö, Allan; Eriksson, Leif a
Source: Self-asserted source
Patricia Saenz-Méndez via ResearcherID
grade
Preferred source (of 2)‎

Ionic liquids as (co)-solvents for nonhydrolytic enzymes

2012 | Book chapter
Part of ISBN: 978-0-470-56904-7
Contributors: Gamenara, Daniela; Saenz-Méndez, Patricia; Seoane, Gustavo; Domínguez de María, Pablo
Source: Self-asserted source
Patricia Saenz-Méndez via ResearcherID

Microwave-assisted solvent-free lipase catalyzed transesterification of β-ketoesters

Green Chemistry Letters and Reviews
2012 | Journal article
DOI: 10.1080/17518253.2012.672596
Contributors: Risso, Mariela; Mazzini, Mauro; Kröger, Santiago; Saenz-Méndez, Patricia; Seoane, Gustavo; Gamenara, Daniela
Source: Self-asserted source
Patricia Saenz-Méndez via ResearcherID
grade
Preferred source (of 2)‎

Redox Biocatalysis: Fundamentals and Applications

2012 | Book
ISBN: 978-0-470-87420-2
Contributors: Gamenara, Daniela; Seoane, Gustavo; Saenz-Méndez, Patricia; Domínguez de María, Pablo
Source: Self-asserted source
Patricia Saenz-Méndez via ResearcherID

C-C bond-forming lyases in organic synthesis

Chemical reviews
2011 | Journal article
DOI: 10.1021/cr100299p
Contributors: Brovetto, Margarita; Gamenara, Daniela; Saenz-Méndez, P.; Seoane, Gustavo a
Source: Self-asserted source
Patricia Saenz-Méndez via ResearcherID
grade
Preferred source (of 2)‎

Computational study on the partial dechlorination of the pesticide chloropicrin by sulfur species

Theoretical Chemistry Accounts
2011 | Journal article
DOI: 10.1007/s00214-011-1057-y
Contributors: Ventura, Oscar N.; Saenz-Méndez, Patricia; Bottinelli, Fiorentina
Source: Self-asserted source
Patricia Saenz-Méndez via ResearcherID
grade
Preferred source (of 2)‎

Organocatalyzed Decarboxylation of Naturally Occurring Cinnamic Acids: Potential Role in Flavoring Chemicals Production

Open Journal of Physical Chemistry
2011 | Journal article
DOI: 10.4236/ojpc.2011.13012
Contributors: Aldabalde, Virginia; Risso, Mariela; Derrudi, Maria Lucia; Geymonat, Federico; Seoane, Gustavo; Gamenara, Daniela; Saenz-Méndez, Patricia
Source: Self-asserted source
Patricia Saenz-Méndez via ResearcherID

Properties and behaviour of tetracyclic allopsoralen derivatives inside a DPPC lipid bilayer model

Physical chemistry chemical physics : PCCP
2011 | Journal article
DOI: 10.1039/c0cp02245d
Contributors: dos Santos, Daniel J. V. a; Saenz-Méndez, Patricia; Eriksson, Leif a; Guedes, Rita C.
Source: Self-asserted source
Patricia Saenz-Méndez via ResearcherID
grade
Preferred source (of 2)‎

Mechanism of the Organocatalyzed Decarboxylative Knoevenagel-Doebner Reaction

The journal of physical chemistry. A
2010 | Journal article
DOI: 10.1021/jp109703f
Contributors: Bermúdez, E.; Ventura, Oscar N.; Saenz-Méndez, P.
Source: Self-asserted source
Patricia Saenz-Méndez via ResearcherID

On the experimental structure of monoperoxocarbonic acid and the enthalpy of formation of carbonic acid, peroxyformic acid and monoperoxocarbonic acid in gas phase

Chemical Physics Letters
2009 | Journal article
DOI: 10.1016/j.cplett.2009.08.062
Contributors: Kieninger, Martina; Saenz Méndez, Patricia; Ventura, Oscar N.
Source: Self-asserted source
Patricia Saenz-Méndez via ResearcherID
grade
Preferred source (of 2)‎

Regioselective epoxide ring-opening using boron trifluoride diethyl etherate: DFT study of an alternative mechanism to explain the formation of syn-fluorohydrins

Journal of Molecular Structure: THEOCHEM
2009 | Journal article
DOI: 10.1016/j.theochem.2009.02.023
Contributors: Saenz Méndez, Patricia; Cachau, Raúl E.; Seoane, Gustavo; Ventura, Oscar N.
Source: Self-asserted source
Patricia Saenz-Méndez via ResearcherID
grade
Preferred source (of 2)‎

Theoretical study of the structure of neutral, radical and anionic monoperoxo carbonic acid

Journal of Molecular Structure: THEOCHEM
2009 | Journal article
DOI: 10.1016/j.theochem.2009.07.029
Contributors: Saenz Méndez, Patricia; Eriksson, Leif a; Ventura, Oscar N.
Source: Self-asserted source
Patricia Saenz-Méndez via ResearcherID
grade
Preferred source (of 2)‎

Theoretical prediction of binding modes and hot sequences for allopsoralen–DNA interaction

Chemical Physics Letters
2007 | Journal article
DOI: 10.1016/j.cplett.2007.10.105
Contributors: Saenz-Méndez, Patricia; Guedes, Rita C.; dos Santos, Daniel J. V. a; Eriksson, Leif a
Source: Self-asserted source
Patricia Saenz-Méndez via ResearcherID

Theoretical Study of Sequence Selectivity and Preferred Binding Mode of Psoralen with DNA

Research Letters in Physical Chemistry
2007 | Journal article
DOI: 10.1155/2007/60623
Contributors: Saenz-Méndez, Patricia; Guedes, Rita C.; dos Santos, Daniel J. V. A.; Eriksson, Leif A.
Source: Self-asserted source
Patricia Saenz-Méndez via ResearcherID
grade
Preferred source (of 2)‎

A new perspective in the Lewis acid catalyzed ring opening of epoxides. Theoretical study of some complexes of methanol, acetic acid, dimethyl ether, diethyl ether, and ethylene oxide with boron trifluoride

The journal of physical chemistry. A
2006 | Journal article
DOI: 10.1021/jp061359y
Contributors: Saenz, Patricia; Cachau, Raúl E.; Seoane, Gustavo; Kieninger, Martina; Ventura, Oscar N.
Source: Self-asserted source
Patricia Saenz-Méndez via ResearcherID

1, 2, 4-Triazine N-oxide derivatives: studies as potential hypoxic cytotoxins. Part II

Archiv der Pharmazie
2004 | Journal article
DOI: 10.1002/ardp.200300782
Contributors: Cerecetto, Hugo; González, Mercedes; Onetto, Silvia; Saenz, Patricia; Ezpeleta, Olga; De Ceráin, Adela López; Monge, Antonio
Source: Self-asserted source
Patricia Saenz-Méndez via ResearcherID

1, 2, 4-Triazine N-oxide derivatives: studies as potential hypoxic cytotoxins. Part III

Archiv der Pharmazie
2004 | Journal article
DOI: 10.1002/ardp.200300839
Contributors: Cerecetto, Hugo; González, Mercedes; Risso, Mariela; Saenz, Patricia; Olea-Azar, Claudio; Bruno, Ana M.; Azqueta, Amaia; De Ceráin, Adela López; Monge, Antonio
Source: Self-asserted source
Patricia Saenz-Méndez via ResearcherID

Synthesis, Biological Evaluation and Modeling Studies of Dual Binding AChE Inhibitors

Medicinal Chemistry Research
2002 | Journal article
Contributors: Castro, A.; Hernandez, L.; Dorronsoro, I.; Saenz, P.; Pérez, C.; Kalko, S.; Orozco, M.; Luque, F. J.; Martínez, A.
Source: Self-asserted source
Patricia Saenz-Méndez via ResearcherID

1,2,4-triazine N-oxide and N,N'-dioxide derivates: studies as potential hypoxic cytotoxins and DNA binder

Medicinal Chemistry Research
2001 | Journal article
Contributors: Cerecetto, H.; González, M.; Onetto, S.; Risso, M.; Saenz, P.; Seoane, G.; Bruno, A. M.; Alarcon, J.; Olea-Azar, C.; López de Ceráin, A. et al.
Source: Self-asserted source
Patricia Saenz-Méndez via ResearcherID

Synthesis and herbicidal activity of N-oxide derivatives

Journal of agricultural and food chemistry
2000 | Journal article
DOI: 10.1021/jf9904766
Contributors: Cerecetto, H.; Dias, E.; Di Maio, R.; González, M.; Pacce, S.; Saenz, P.; Seoane, G.; Suescun, L.; Mombrú, A.; Fernández, G. et al.
Source: Self-asserted source
Patricia Saenz-Méndez via ResearcherID

1,2,5-Oxadiazole N-oxide derivatives and related compounds as potential antitrypanosomal drugs: structure-activity relationships

Journal of medicinal chemistry
1999 | Journal article
DOI: 10.1021/jm9805790
Contributors: Cerecetto, H.; Di Maio, R.; González, M.; Risso, M.; Saenz, P.; Seoane, G.; Denicola, A.; Peluffo, G.; Quijano, C.; Olea-Azar, C.
Source: Self-asserted source
Patricia Saenz-Méndez via ResearcherID

Peer review (79 reviews for 20 publications/grants)

Review activity for ACS omega. (3)
Review activity for Biochemistry. (2)
Review activity for Biomolecules. (2)
Review activity for Computational biology and chemistry (5)
Review activity for Environmental pollution. (1)
Review activity for Interdisciplinary sciences: computational life sciences. (3)
Review activity for Interdisciplinary sciences: computational life sciences. (1)
Review activity for International journal of biological macromolecules. (4)
Review activity for International journal of molecular sciences. (1)
Review activity for Journal of biophysical chemistry (2)
Review activity for Journal of molecular modeling. (33)
Review activity for Journal of molecular modeling. (7)
Review activity for Journal of organic chemistry. (4)
Review activity for Journal of organic chemistry. (1)
Review activity for Letters in organic chemistry. (1)
Review activity for Molecular informatics (1)
Review activity for Molecules. (1)
Review activity for Recent innovations in chemical engineering. (1)
Review activity for Scientific reports. (1)
Review activity for Theoretical Chemistry accounts. (5)
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