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mitochondria
Spain

Activities

Employment (1)

Universidad de Castilla-La Mancha: Campus de Toledo, Castilla-La Mancha, ES

2003 to present | Profesor Titular de Universidad (Departamento de Química Orgánica, Inorgánica y Bioquímica)
Employment
Source: Self-asserted source
Araceli del Arco

Works (50 of 56)

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IF1 ablation prevents ATP synthase oligomerization, enhances mitochondrial ATP turnover and promotes an adenosine-mediated pro-inflammatory phenotype.

Cell death & disease
2023-07-12 | Journal article
Contributors: Sonia Dominguez Zorita; Inés Romero; Santacatterina F; Pau B. Esparza-Moltó; Simó C; Del-Arco A; Cristina Núñez de Arenas; Saiz J; Coral Barbas; Jose Manuel Cuezva Marcos
Source: Self-asserted source
Araceli del Arco

Regulation of neuronal energy metabolism by calcium: Role of MCU and Aralar/malate-aspartate shuttle.

Biochimica et biophysica acta. Molecular cell research
2023-03-28 | Journal article
Contributors: Del Arco A; González-Moreno L; Pérez-Liébana I; Juaristi I; González-Sánchez P; Contreras L; Pardo B; Satrústegui J
Source: Self-asserted source
Araceli del Arco

Exogenous aralar/slc25a12 can replace citrin/slc25a13 as malate aspartate shuttle component in liver.

Molecular genetics and metabolism reports
2023-03-16 | Journal article
Contributors: González-Moreno L; Santamaría-Cano A; Paradela A; Martínez-Chantar ML; Martín MÁ; Pérez-Carreras M; García-Picazo A; Vázquez J; Calvo E; González-Aseguinolaza G et al.
Source: Self-asserted source
Araceli del Arco

A Ca<sup>2+</sup>-Dependent Mechanism Boosting Glycolysis and OXPHOS by Activating Aralar-Malate-Aspartate Shuttle, upon Neuronal Stimulation.

The Journal of neuroscience : the official journal of the Society for Neuroscience
2022-04-06 | Journal article
Contributors: Pérez-Liébana I; Juaristi I; González-Sánchez P; González-Moreno L; Eduardo Rial; Podunavac M; Zakarian A; Molgó J; Ainara Vallejo-Illarramendi; Laura Mosqueira-Martín et al.
Source: Self-asserted source
Araceli del Arco

AGC1 Deficiency: Pathology and Molecular and Cellular Mechanisms of the Disease.

International journal of molecular sciences
2022-01-04 | Journal article
Contributors: Pardo B; Herrada-Soler E; Jorgina Satrustegui Gil Delgado; Laura Contreras; Del Arco A
Source: Self-asserted source
Araceli del Arco

The mitochondrial aspartate/glutamate carrier (AGC or Aralar1) isoforms in D. melanogaster: biochemical characterization, gene structure, and evolutionary analysis.

Biochimica et biophysica acta. General subjects
2021-01-23 | Journal article
Contributors: Paola LUNETTI; René Marsano; rosita curcio; Dolce V; Fiermonte G; anna rita cappello; Marra F; Moschetti R; Li Y; Aiello D et al.
Source: Self-asserted source
Araceli del Arco

Mitochondrial movement in Aralar/Slc25a12/AGC1 deficient cortical neurons.

Neurochemistry international
2019-08-28 | Journal article
Contributors: Puertas-Frías G; Del Arco A; Pardo B; Satrústegui J; Laura Contreras
Source: Self-asserted source
Araceli del Arco

The Response to Stimulation in Neurons and Astrocytes.

Neurochemical research
2019-04-23 | Journal article
Contributors: Juaristi I; Laura Contreras; Paloma Gonzalez Sanchez; Irene Pérez-Liébana; Luis González-Moreno; Pardo B; Del Arco A; Satrústegui J
Source: Self-asserted source
Araceli del Arco

Calcium Deregulation and Mitochondrial Bioenergetics in GDAP1-Related CMT Disease

International Journal of Molecular Sciences
2019-01 | Journal article | Author
Contributors: Paloma González-Sánchez; Jorgina Satrustegui Gil Delgado; Francesc Palau; Araceli del Arco
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Multidisciplinary Digital Publishing Institute
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Preferred source (of 2)‎

Extracellular ATP and glutamate drive pyruvate production and energy demand to regulate mitochondrial respiration in astrocytes.

Glia
2019-01-09 | Journal article
Contributors: Juaristi I; Llorente-Folch I; Jorgina Satrustegui Gil Delgado; Del Arco A
Source: Self-asserted source
Araceli del Arco

Store-Operated Calcium Entry Is Required for mGluR-Dependent Long Term Depression in Cortical Neurons.

Frontiers in cellular neuroscience
2017-12-14 | Journal article
Contributors: Paloma Gonzalez Sanchez; Del Arco A; Esteban JA; Jorgina Satrustegui Gil Delgado
Source: Self-asserted source
Araceli del Arco

De Novo Mutations in SLC25A24 Cause a Disorder Characterized by Early Aging, Bone Dysplasia, Characteristic Face, and Early Demise.

American journal of human genetics
2017-11-01 | Journal article
Contributors: Writzl K; Maver A; Kovačič L; Martinez-Valero P; Laura Contreras; Jorgina Satrustegui Gil Delgado; Marco Castori; Faivre L; Pablo Lapunzina; André van Kuilenburg et al.
Source: Self-asserted source
Araceli del Arco

CMT-linked loss-of-function mutations in GDAP1 impair store-operated Ca<sup>2+</sup> entry-stimulated respiration.

Scientific reports
2017-02-21 | Journal article
Contributors: Paloma Gonzalez Sanchez; David Pla-Martín; Martínez-Valero P; Rueda CB; Eduardo Calpena; Del Arco A; Francesc Palau; Jorgina Satrustegui Gil Delgado
Source: Self-asserted source
Araceli del Arco

Calcium regulation of mitochondrial carriers

Biochimica et Biophysica Acta - Molecular Cell Research
2016 | Journal article
EID:

2-s2.0-84964370071

Contributors: del Arco, A.; Contreras, L.; Pardo, B.; Satrustegui, J.
Source: Self-asserted source
Araceli del Arco via Scopus - Elsevier

Glutamate excitotoxicity and Ca<sup>2+</sup>-regulation of respiration: Role of the Ca<sup>2+</sup> activated mitochondrial transporters (CaMCs)

Biochimica et Biophysica Acta - Bioenergetics
2016 | Journal article
EID:

2-s2.0-84963969164

Contributors: Rueda, C.B.; Llorente-Folch, I.; Traba, J.; Amigo, I.; Gonzalez-Sanchez, P.; Contreras, L.; Juaristi, I.; Martinez-Valero, P.; Pardo, B.; del Arco, A. et al.
Source: Self-asserted source
Araceli del Arco via Scopus - Elsevier

Mitochondrial ATP-Mg/pi carrier SCaMC-3/Slc25a23 counteracts PARP-1-dependent fall in mitochondrial ATP caused by excitotoxic insults in neurons

Journal of Neuroscience
2015 | Journal article
EID:

2-s2.0-84923363265

Contributors: Rueda, X.B.; Traba, J.; Amigo, I.; Llorente-Folch, I.; González-Sánchez, P.; Pardo, B.; Esteban, J.A.; Del Arco, A.; Satrústegui, J.
Source: Self-asserted source
Araceli del Arco via Scopus - Elsevier

PKA Phosphorylates the ATPase Inhibitory Factor 1 and Inactivates Its Capacity to Bind and Inhibit the Mitochondrial H<sup>+</sup>-ATP Synthase

Cell Reports
2015 | Journal article
EID:

2-s2.0-84942816776

Contributors: García-Bermúdez, J.; Sánchez-Aragó, M.; Soldevilla, B.; del Arco, A.; Nuevo-Tapioles, C.; Cuezva, J.M.
Source: Self-asserted source
Araceli del Arco via Scopus - Elsevier

Ca<sup>2 +</sup> regulation of mitochondrial function in neurons

Biochimica et Biophysica Acta - Bioenergetics
2014 | Journal article
EID:

2-s2.0-84905784762

Contributors: Rueda, C.B.; Llorente-Folch, I.; Amigo, I.; Contreras, L.; González-Sánchez, P.; Martínez-Valero, P.; Juaristi, I.; Pardo, B.; Del Arco, A.; Satrústegui, J.
Source: Self-asserted source
Araceli del Arco via Scopus - Elsevier

Calcium-regulation of mitochondrial respiration maintains ATP homeostasis and requires ARALAR/AGC1-malate aspartate shuttle in intact cortical neurons

Journal of Neuroscience
2013 | Journal article
EID:

2-s2.0-84882980197

Contributors: Llorente-Folch, I.; Rueda, C.B.; Amigo, I.; del Arco, A.; Saheki, T.; Pardo, B.; Satrústegui, J.
Source: Self-asserted source
Araceli del Arco via Scopus - Elsevier

Glucagon regulation of oxidative phosphorylation requires an increase in matrix adenine nucleotide content through Ca2+ activation of the mitochondrial ATP-Mg/Pi carrier SCaMC-3

Journal of Biological Chemistry
2013 | Journal article
EID:

2-s2.0-84875141425

Contributors: Amigo, I.; Traba, J.; González-Barroso, M.M.; Rueda, C.B.; Fernández, M.; Rial, E.; Sánchez, A.; Satrústegui, J.; Del Arco, A.
Source: Self-asserted source
Araceli del Arco via Scopus - Elsevier

Clonal Human Fetal Ventral Mesencephalic Dopaminergic Neuron Precursors for Cell Therapy Research

PLoS ONE
2012 | Journal article
EID:

2-s2.0-84871792575

Contributors: Ramos-Moreno, T.; Lendínez, J.G.; Pino-Barrio, M.J.; del Arco, A.; Martínez-Serrano, A.
Source: Self-asserted source
Araceli del Arco via Scopus - Elsevier

SCaMC-1 promotes cancer cell survival by desensitizing mitochondrial permeability transition via ATP/ADP-mediated matrix Ca 2 buffering

Cell Death and Differentiation
2012 | Journal article
EID:

2-s2.0-84858158689

Contributors: Traba, J.; Del Arco, A.; Duchen, M.R.; Szabadkai, G.; Satrústegui, J.
Source: Self-asserted source
Araceli del Arco via Scopus - Elsevier

SCaMC-1Like a member of the mitochondrial carrier (mc) family preferentially expressed in testis and localized in mitochondria and chromatoid body

PLoS ONE
2012 | Journal article
EID:

2-s2.0-84863676916

Contributors: Amigo, I.; Traba, J.; Satrústegui, J.; del Arco, A.
Source: Self-asserted source
Araceli del Arco via Scopus - Elsevier

Adenine nucleotide transporters in organelles: Novel genes and functions

Cellular and Molecular Life Sciences
2011 | Journal article
EID:

2-s2.0-79953688974

Contributors: Traba, J.; Satrústegui, J.; Del Arco, A.
Source: Self-asserted source
Araceli del Arco via Scopus - Elsevier

Deficiency of the mitochondrial transporter of aspartate/glutamate aralar/AGC1 causes hypomyelination and neuronal defects unrelated to myelin deficits in mouse brain

Journal of Neuroscience Research
2011 | Journal article
EID:

2-s2.0-80053641826

Contributors: Ramos, M.; Pardo, B.; Llorente-Folch, I.; Saheki, T.; del Arco, A.; Satrústegui, J.
Source: Self-asserted source
Araceli del Arco via Scopus - Elsevier

S-resistin inhibits adipocyte differentiation and increases TNFα expression and secretion in 3T3-L1 cells

Biochimica et Biophysica Acta - Molecular Cell Research
2010 | Journal article
EID:

2-s2.0-77955660747

Contributors: Fernández, C.M.; del Arco, A.; Gallardo, N.; Aguado, L.; Rodriguez, M.; Ros, M.; Carrascosa, J.M.; Andrés, A.; Arribas, C.
Source: Self-asserted source
Araceli del Arco via Scopus - Elsevier

Characterization of SCaMC-3-like/slc25a41, a novel calcium-independent mitochondrial ATP-Mg/Pi carrier

Biochemical Journal
2009 | Journal article
EID:

2-s2.0-59849112359

Contributors: Traba, J.; Satrústegui, J.; del Arco, A.
Source: Self-asserted source
Araceli del Arco via Scopus - Elsevier

The expression of rat resistin isoforms is differentially regulated in visceral adipose tissues: effects of aging and food restriction

Metabolism: Clinical and Experimental
2009 | Journal article
EID:

2-s2.0-58249131167

Contributors: Fernández, C.M.; Moltó, E.; Gallardo, N.; del Arco, A.; Martínez, C.; Andrés, A.; Ros, M.; Carrascosa, J.M.; Arribas, C.
Source: Self-asserted source
Araceli del Arco via Scopus - Elsevier

Transport of adenine nucleotides in the mitochondria of Saccharomyces cerevisiae: Interactions between the ADP/ATP carriers and the ATP-Mg/Pi carrier

Mitochondrion
2009 | Journal article
EID:

2-s2.0-62549139614

Contributors: Traba, J.; Satrústegui, J.; del Arco, A.
Source: Self-asserted source
Araceli del Arco via Scopus - Elsevier

Requirement for aralar and its Ca2+-binding sites in Ca2+ signal transduction in mitochondria from INS-1 clonal beta-cells.

2009-01 | Journal article
Contributors: Mármol P; Pardo B; Wiederkehr A; del Arco A; Wollheim CB; Satrústegui J
Source: Self-asserted source
Araceli del Arco via Europe PubMed Central

Yeast mitochondria import ATP through the calcium-dependent ATP-Mg/Pi carrier Sal1p, and are ATP consumers during aerobic growth in glucose

Molecular Microbiology
2008 | Journal article
EID:

2-s2.0-46949105141

Contributors: Traba, J.; Froschauer, E.M.; Wiesenberger, G.; Satrústegui, J.; Del Arco, A.
Source: Self-asserted source
Araceli del Arco via Scopus - Elsevier

Mitochondrial transporters as novel targets for intracellular calcium signaling

Physiological Reviews
2007 | Journal article
EID:

2-s2.0-33846796330

Contributors: Satrústegui, J.; Pardo, B.; Del Arco, A.
Source: Self-asserted source
Araceli del Arco via Scopus - Elsevier

Role of aralar, the mitochondrial transporter of aspartate-glutamate, in brain N-acetylaspartate formation and Ca2+ signaling in neuronal mitochondria

Journal of Neuroscience Research
2007 | Journal article
EID:

2-s2.0-35848969787

Contributors: Satrústegui, J.; Contreras, L.; Ramos, M.; Marmol, P.; Del Arco, A.; Saheki, T.; Pardo, B.
Source: Self-asserted source
Araceli del Arco via Scopus - Elsevier

Cloning, tissue expression and metal inducibility of an ubiquitous metallothionein from Panulirus argus

Gene
2005 | Journal article
EID:

2-s2.0-27144531040

Contributors: Moltó, E.; Bonzón-Kulichenko, E.; Del Arco, A.; López-Alañón, D.M.; Carrillo, O.; Gallardo, N.; Andrés, A.
Source: Self-asserted source
Araceli del Arco via Scopus - Elsevier

New mitochondrial carriers: An overview

Cellular and Molecular Life Sciences
2005 | Journal article
EID:

2-s2.0-27144525581

Contributors: Del Arco, A.; Satrústegui, J.
Source: Self-asserted source
Araceli del Arco via Scopus - Elsevier

Novel variants of human SCaMC-3, an isoform of the ATP-Mg/Pi mitochondrial carrier, generated by alternative splicing from 3′-flanking transposable elements

Biochemical Journal
2005 | Journal article
EID:

2-s2.0-23644440525

Contributors: Del Arco, A.
Source: Self-asserted source
Araceli del Arco via Scopus - Elsevier

Reduced N-acetylaspartate levels in mice lacking aralar, a brain- and muscle-type mitochondrial aspartate-glutamate carrier

Journal of Biological Chemistry
2005 | Journal article
EID:

2-s2.0-24744452808

Contributors: Jalil, Md.A.; Begumi, L.; Contreras, L.; Pardo, B.; Iijima, M.; Li, M.X.; Ramos, M.; Marmol, P.; Horiuchi, M.; Shimotsu, K. et al.
Source: Self-asserted source
Araceli del Arco via Scopus - Elsevier

The calcium-dependent ATP-Mg/Pi mitochondrial carrier is a target of glucose-induced calcium signalling in Saccharomyces cerevisiae

Biochemical Journal
2005 | Journal article
EID:

2-s2.0-29644439674

Contributors: Cavero, S.; Traba, J.; Del Arco, A.; Satrústegui, J.
Source: Self-asserted source
Araceli del Arco via Scopus - Elsevier

Identification of a novel human subfamily of mitochondrial carriers with calcium-binding domains

Journal of Biological Chemistry
2004 | Journal article
EID:

2-s2.0-2642522210

Contributors: Del Arco, A.; Satrústegui, J.
Source: Self-asserted source
Araceli del Arco via Scopus - Elsevier

The malate-aspartate NADH shuttle member aralar1 determines glucose metabolic fate, mitochondrial activity, and insulin secretion in beta cells

Journal of Biological Chemistry
2004 | Journal article
EID:

2-s2.0-11244318158

Contributors: Rubi, B.; Del Arco, A.; Bartley, C.; Satrustegui, J.; Maechler, P.
Source: Self-asserted source
Araceli del Arco via Scopus - Elsevier

Alternative splicing generates a novel non-secretable resistin isoform in Wistar rats

FEBS Letters
2003 | Journal article
EID:

2-s2.0-0344440754

Contributors: Del Arco, A.; Peralta, S.; Carrascosa, J.M.; Ros, M.; Andrés, A.; Arribas, C.
Source: Self-asserted source
Araceli del Arco via Scopus - Elsevier

Developmental changes in the Ca2+-regulated mitochondrial aspartate-glutamate carrier aralar1 in brain and prominent expression in the spinal cord

Developmental Brain Research
2003 | Journal article
EID:

2-s2.0-0038632103

Contributors: Ramos, M.; Del Arco, A.; Pardo, B.; Martínez-Serrano, A.; Martínez-Morales, J.R.; Kobayashi, K.; Yasuda, T.; Bogónez, E.; Bovolenta, P.; Saheki, T. et al.
Source: Self-asserted source
Araceli del Arco via Scopus - Elsevier

Identification and metabolic role of the mitochondrial aspartate-glutamate transporter in Saccharomyces cerevisiae

Molecular Microbiology
2003 | Journal article
EID:

2-s2.0-10744230390

Contributors: Cavero, S.; Vozza, A.; Del Arco, A.; Palmieri, L.; Villa, A.; Blanco, E.; Runswick, M.J.; Walker, J.E.; Cerdán, S.; Palmieri, F. et al.
Source: Self-asserted source
Araceli del Arco via Scopus - Elsevier

Expression of the aspartate/glutamate mitochondrial carriers aralar1 and citrin during development and in adult rat tissues

European Journal of Biochemistry
2002 | Journal article
EID:

2-s2.0-0036306987

Contributors: Del Arco, A.; Morcillo, J.; Martínez-Morales, J.R.; Galián, C.; Martos, V.; Bovolenta, P.; Satrústegui, J.
Source: Self-asserted source
Araceli del Arco via Scopus - Elsevier

Expression of three mitochondrial solute carriers, citrin, aralar1 and ornithine transporter, in relation to urea cycle in mice

Biochimica et Biophysica Acta - Gene Structure and Expression
2002 | Journal article
EID:

2-s2.0-0037066593

Contributors: Begum, L.; Jalil, Md.Abdul; Kobayashi, K.; Iijima, M.; Li, M.X.; Yasuda, T.; Horiuchi, M.; Del Arco, A.; Satrústegui, J.; Saheki, T.
Source: Self-asserted source
Araceli del Arco via Scopus - Elsevier

Citrin and aralar1 are Ca2+-stimulated aspartate/glutamate transporters in mitochondria

EMBO Journal
2001 | Journal article
EID:

2-s2.0-17944378173

Contributors: Palmieri, L.; Pardo, B.; Lasorsa, F.M.; Del Arco, A.; Kobayashi, K.; Iijima, M.; Runswick, M.J.; Walker, J.E.; Saheki, T.; Satrústegui, J. et al.
Source: Self-asserted source
Araceli del Arco via Scopus - Elsevier

Assignment of the calcium-binding mitochondrial carrier Aralar1 gene (SLC25A12) to human chromosome band 2q31 by in situ hybridization

Cytogenetics and Cell Genetics
2000 | Journal article
EID:

2-s2.0-0033820495

Contributors: Sanz, R.; Del Arco, A.; Ayuso, C.; Ramos, C.; Satrústegui, J.
Source: Self-asserted source
Araceli del Arco via Scopus - Elsevier

Characterization of a second member of the subfamily of calcium-binding mitochondrial carriers expressed in human non-excitable tissues

Biochemical Journal
2000 | Journal article
EID:

2-s2.0-0034141637

Contributors: Del Arco, A.; Agudo, M.; Satrústegui, J.
Source: Self-asserted source
Araceli del Arco via Scopus - Elsevier

BDNF gene transfer to the mammalian brain using CNS-derived neural precursors

Gene Therapy
1999 | Journal article
EID:

2-s2.0-0032711822

Contributors: Rubio, F.T.; Kokaia, Z.; Del Arco, A.; García-Simón, M.I.; Snyder, E.Y.; Lindvall, O.; Satrústegui, J.; Martínez-Serrano, A.
Source: Self-asserted source
Araceli del Arco via Scopus - Elsevier

Molecular cloning of aralar, a new member of the mitochondrial carrier superfamily that binds calcium and is present in human muscle and brain

Journal of Biological Chemistry
1998 | Journal article
EID:

2-s2.0-0032483516

Contributors: Del Arco, A.; Satrústegui, J.
Source: Self-asserted source
Araceli del Arco via Scopus - Elsevier
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