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CEA Saclay: Gif-sur-Yvette, FR

2007-10-02 to present | research engineer
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Florence Castelli

Works (50 of 56)

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Nontargeted urine metabolomic analysis of acute intermittent porphyria reveals novel interactions between bile acids and heme metabolism: New promising biomarkers for the long‐term management of patients

Journal of Inherited Metabolic Disease
2024-10-25 | Journal article
Contributors: Thibaud Lefebvre; Thibaut Eguether; Etienne Thévenot; Antoine Poli; Emeline Chu-Van; Pranvera Krasniqi; Caroline Schmitt; Neila Talbi; Gaël Nicolas; Hervé Puy et al.
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Florence Castelli via HAL

Red blood cell metabolomics identify ergothioneine as a key metabolite in DMARD-naïve rheumatoid arthritis and response to methotrexate

Scientific Reports
2024-09-09 | Journal article
Contributors: Johanna Sigaux; Christophe Junot; Marie-Christophe Boissier; Mylène Petit; Magali Breckler; Florence Castelli; François Fenaille; Paul-Henri Roméo; Luca Semerano
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Florence Castelli via HAL

Metabolomics Analysis of Rabbit Plasma after Ocular Exposure to Vapors of Sulfur Mustard

Metabolites
2024-06-21 | Journal article
Contributors: Jihéne Bouhlel; Fanny Caffin; Fanny Gros-Désormeaux; Thierry Douki; Jean-François Benoist; Florence A. Castelli; Emeline Chu-Van; Christophe Piérard; Christophe Junot; François Fenaille
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In-depth characterization of a selection of gut commensal bacteria reveals their functional capacities to metabolize dietary carbohydrates with prebiotic potential

mSystems
2024-04-16 | Journal article
Contributors: Cassandre Bedu-Ferrari; Paul Biscarrat; Frederic Pepke; Sarah Vati; Cyril Chaudemanche; Florence Castelli; Céline Chollet; Olivier Rué; Christelle Hennequet-Antier; Philippe Langella et al.
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Florence Castelli via HAL

Untargeted Metabolomics: Extraction of Plasma Metabolites v1

2024-02-19 | Preprint
Contributors: florence castelli; emeline.chu-van CHU-VAN
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Untargeted Metabolomics: Extraction of Plasma Metabolites v2

2024-02-19 | Preprint
Contributors: florence castelli; emeline.chu-van CHU-VAN
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Metabolomic changes in adults with status epilepticus: A human case–control study

Epilepsia
2024-02-10 | Journal article
Contributors: Aurélie Hanin; Céline Chollet; Sophie Demeret; Lucas Di Meglio; Vincent Navarro; Florence Castelli
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Florence Castelli via HAL

Assessment of local and systemic signature of eosinophilic esophagitis (EoE) in children through multi-omics approaches

Frontiers in Immunology
2023-03-15 | Journal article
Part of ISSN: 1664-3224
Contributors: Karine Adel-Patient; Florence Campeotto; Marta Grauso; Blanche Guillon; Marco Moroldo; Eric Venot; Céline Dietrich; François Machavoine; Florence A. Castelli; François Fenaille et al.
Source: Self-asserted source
Florence Castelli

Development of an Untargeted Metabolomics Strategy to Study the Metabolic Rewiring of Dendritic Cells upon Lipopolysaccharide Activation

Metabolites
2023-02-21 | Journal article
Contributors: Jessica Michieletto; Aurélie Delvaux; Emeline Chu-Van; Christophe Junot; François Fenaille; Florence A. Castelli
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Sympathetic nervous activation, mitochondrial dysfunction and outcome in acutely decompensated cirrhosis: the metabolomic prognostic models (CLIF-C MET)

Gut
2023-02-14 | Journal article
Part of ISSN: 0017-5749
Part of ISSN: 1468-3288
Contributors: Emmanuel Weiss; Carlos de la Peña-Ramirez; Ferran Aguilar; Juan-Jose Lozano; Cristina Sánchez-Garrido; Patricia Sierra; Pedro Izquierdo-Bueno Martin; Juan Manuel Diaz; François Fenaille; Florence A Castelli et al.
Source: Self-asserted source
Florence Castelli

Despite similar clinical features metabolomics reveals distinct signatures in insulin resistant and progressively obese minipigs

Journal of Physiology and Biochemistry
2022-12-27 | Journal article
Part of ISSN: 1138-7548
Part of ISSN: 1877-8755
Contributors: Imene Bousahba; Jérémie David; Florence Castelli; Céline Chollet; Sadia Ouzia; François Fenaille; Didier Rémond; Nathalie Poupin; Sergio Polakof
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Florence Castelli
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Identification of the Major Degradation Pathways of Selumetinib

Pharmaceutics
2022-11-30 | Journal article | Author
Part of ISSN: 1999-4923
Contributors: Tahar Sif eddine Bouchema; maxime annereau; Victoire Vieillard; Raphael Boquet; Gisele Abreu Coelho; Florence Castelli; Audrey Solgadi; Muriel Paul; Najet Yagoubi; Philippe-Henri Secrétan et al.
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Florence Castelli
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Using a multiomics approach to unravel a septic shock specific signature in skeletal muscle

Scientific Reports
2022-11-05 | Journal article
Part of ISSN: 2045-2322
Contributors: Baptiste Duceau; Michael Blatzer; Jean Bardon; Thibault Chaze; Quentin Giai Gianetto; Florence Castelli; François Fenaille; Lucie Duarte; Thomas Lescot; Christophe Tresallet et al.
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Florence Castelli
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Relevance of the TRIAP1/p53 axis in colon cancer cell proliferation and adaptation to glutamine deprivation

Frontiers in Oncology
2022-10-31 | Journal article
Part of ISSN: 2234-943X
Contributors: Kenza Nedara; Camille Reinhardt; Emilie Lebraud; Giuseppe Arena; Céline Gracia; Valérie Buard; Catherine Pioche-Durieu; Florence Castelli; Benoit Colsch; Paule Bénit et al.
Source: Self-asserted source
Florence Castelli

Cystine uptake inhibition potentiates front-line therapies in acute myeloid leukemia

Leukemia
2022-06 | Journal article
Part of ISSN: 0887-6924
Part of ISSN: 1476-5551
Contributors: Bryann Pardieu; Justine Pasanisi; Frank Ling; Reinaldo Dal Bello; Justine Penneroux; Angela Su; Romane Joudinaud; Laureen Chat; Hsin Chieh Wu; Matthieu Duchmann et al.
Source: Self-asserted source
Florence Castelli

The Human Meconium Metabolome and Its Evolution during the First Days of Life

Metabolites
2022-05-05 | Journal article | Author
Part of ISSN: 2218-1989
Contributors: Nihel Bekhti; Florence Castelli; Alain Paris; Blanche Guillon; Christophe Junot; Clémence Moiron; Francois Fenaille; Karine Adel-Patient
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Florence Castelli
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Chronic Consumption of Cocoa Rich in Procyanidins Has a Marginal Impact on Gut Microbiota and on Serum and Fecal Metabolomes in Male Endurance Athletes

Journal of Agricultural and Food Chemistry
2022-02-16 | Journal article
Part of ISSN: 0021-8561
Part of ISSN: 1520-5118
Contributors: Mariangela Tabone; Jose Angel García-Merino; Carlo Bressa; Nuria Elizabeth Rocha Guzmán; Karen Herrera Rocha; Emeline Chu Van; Florence A. Castelli; Francois Fenaille; MAR LARROSA
Source: Self-asserted source
Florence Castelli

Metabolomics for personalized medicine: the input of analytical chemistry from biomarker discovery to point-of-care tests

Analytical and Bioanalytical Chemistry
2022-01 | Journal article
Part of ISSN: 1618-2642
Part of ISSN: 1618-2650
Contributors: Florence Anne Castelli; Giulio Rosati; Christian Moguet; Celia Fuentes; Jose Marrugo-Ramírez; Thibaud Lefebvre; Hervé Volland; Arben Merkoçi; Stéphanie Simon; François Fenaille et al.
Source: Self-asserted source
Florence Castelli
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Metabolomics in the understanding and management of hepatic encephalopathy

Analytical Biochemistry
2022-01 | Journal article
Part of ISSN: 0003-2697
Contributors: Juliette Pelle; Florence A. Castelli; Marika Rudler; Imen Alioua; Benoit Colsch; François Fenaille; Christophe Junot; Dominique Thabut; Nicolas WEISS
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Florence Castelli

ProMetIS, deep phenotyping of mouse models by combined proteomics and metabolomics analysis

Scientific Data
2021-12-03 | Journal article
Part of ISSN: 2052-4463
Contributors: Alyssa Imbert; Magali Rompais; Mohammed Selloum; Florence Castelli; Emmanuelle Mouton-Barbosa; Marion Brandolini-Bunlon; Emeline Chu-Van; Charlotte Joly; Aurélie Hirschler; Pierrick Roger et al.
Source: Self-asserted source
Florence Castelli

Untargeted lipidomics uncovers lipid signatures that distinguish severe from moderate forms of acutely decompensated cirrhosis

Journal of Hepatology
2021-11 | Journal article
Part of ISSN: 0168-8278
Contributors: Joan Clària; Anna Curto Vilalta; Richard Moreau; Benoit Colsch; Cristina López-Vicario; Juan José Lozano; Ferran Aguilar; Florence A. Castelli; François Fenaille; Christophe Junot et al.
Source: Self-asserted source
Florence Castelli

Activation of Vitamin D Receptor Pathway Enhances Differentiating Capacity in Acute Myeloid Leukemia with Isocitrate Dehydrogenase Mutations

Cancers
2021-10-19 | Journal article | Author
Part of ISSN: 2072-6694
Contributors: Marie Sabatier; Emeline Boet; Sonia Zaghdoudi; Nathan Guiraud; Alexis Hucteau; Nathaniel Polley; Guillaume Cognet; Estelle Saland; Laura Lauture; Thomas Farge et al.
Source: Self-asserted source
Florence Castelli
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Arginine-selective modulation of the lysosomal transporter PQLC2 through a gate-tuning mechanism

Proceedings of the National Academy of Sciences
2021-08-10 | Journal article
Contributors: Xavier Leray; Rossella Conti; Yan Li; Cécile Debacker; Florence Castelli; François Fenaille; Anselm A. Zdebik; Michael Pusch; Bruno Gasnier
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Multiplatform metabolomics for an integrative exploration of metabolic syndrome in older men

eBioMedicine
2021-07 | Journal article
Part of ISSN: 2352-3964
Contributors: Blandine Comte; Stéphanie Monnerie; Marion Brandolini-Bunlon; Cécile Canlet; Florence Castelli; Emeline Chu-Van; Benoit Colsch; François Fenaille; Charlotte Joly; Fabien Jourdan et al.
Source: Self-asserted source
Florence Castelli

Assessing the role of amino acids in systemic inflammation and organ failure in patients with ACLF

Journal of Hepatology
2021-05 | Journal article
Part of ISSN: 0168-8278
Contributors: Giacomo Zaccherini; Ferran Aguilar; Paolo Caraceni; Joan Clària; Juan José Lozano; François Fenaille; Florence Castelli; Christophe Junot; Anna Curto Vilalta; Chiara Formentin et al.
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Florence Castelli
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Mitochondrial metabolism supports resistance to IDH mutant inhibitors in acute myeloid leukemia

Journal of Experimental Medicine
2021-05-03 | Journal article | Author
Part of ISSN: 0022-1007
Part of ISSN: 1540-9538
Contributors: Lucille Stuani; Marie Sabatier; Estelle Saland; Guillaume Cognet; Nathalie Poupin; Claudie Bosc; Florence Castelli; GALES; Evegnia Turtoi; camille et al.
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Florence Castelli
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The effect of acute moderate-intensity exercise on the serum and fecal metabolomes and the gut microbiota of cross-country endurance athletes

Scientific Reports
2021-02-11 | Journal article
Part of ISSN: 2045-2322
Contributors: Mariangela Tabone; Carlo Bressa; Jose Angel García-Merino; Diego Moreno-Pérez; Emeline Chu Van; Florence A. Castelli; François Fenaille; Mar Larrosa
Source: Self-asserted source
Florence Castelli

Metabotypes of Pseudomonas aeruginosa Correlate with Antibiotic Resistance, Virulence and Clinical Outcome in Cystic Fibrosis Chronic Infections

Metabolites
2021-01-21 | Journal article
Part of ISSN: 2218-1989
Contributors: Oriane Moyne; Florence Castelli; Dominique Bicout; Julien Boccard; Boubou Camara; Benoit Cournoyer; Eric Faudry; Terrier Samuel; Dalil Hannani; Sarah Huot-Marchand et al.
Source: Self-asserted source
Florence Castelli

The Adipose Microenvironment Dysregulates the Mammary Myoepithelial Cells and Could Participate to the Progression of Breast Cancer

Frontiers in Cell and Developmental Biology
2021-01-11 | Journal article
Part of ISSN: 2296-634X
Contributors: Laetitia Delort; Juliette Cholet; Caroline Decombat; Marion Vermerie; Charles Dumontet; Florence A. Castelli; François Fenaille; Céline Auxenfans; Adrien Rossary; Florence Caldefie-Chezet
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Florence Castelli
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Gout and pseudo-gout-related crystals promote GLUT1-mediated glycolysis that governs NLRP3 and interleukin-1β activation on macrophages

Annals of the Rheumatic Diseases
2020-11 | Journal article
Part of ISSN: 0003-4967
Part of ISSN: 1468-2060
Contributors: Felix Renaudin; Lucie Orliaguet; Florence Castelli; François Fenaille; Aurelie Prignon; Fawaz Alzaid; Christele Combes; Aurélie Delvaux; Yasmina Adimy; Martine Cohen-Solal et al.
Source: Self-asserted source
Florence Castelli

Blood metabolomics uncovers inflammation-associated mitochondrial dysfunction as a potential mechanism underlying ACLF

Journal of Hepatology
2020-04 | Journal article | Author
Part of ISSN: 0168-8278
Contributors: Richard Moreau; Joan Clària; Ferran Aguilar; François Fenaille; Juan José Lozano; Christophe Junot; Benoit Colsch; Paolo Caraceni; Jonel Trebicka; Marco Pavesi et al.
Source: Self-asserted source
Florence Castelli
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Metabolomic Investigation of Staphylococcus aureus Antibiotic Susceptibility by Liquid Chromatography Coupled to High-Resolution Mass Spectrometry

Functional Proteomics
2019 | Book chapter
Part of ISBN: 9781493988136
Part of ISBN: 9781493988143
Part of ISSN: 1064-3745
Part of ISSN: 1940-6029
Contributors: Sandrine Aros-Calt; Florence A. Castelli; Patricia Lamourette; Gaspard Gervasi; Christophe Junot; Bruno H. Muller; François Fenaille
Source: Self-asserted source
Florence Castelli

Immune components of early breastmilk: Association with maternal factors and with reported food allergy in childhood

Pediatric Allergy and Immunology
2019-02 | Journal article
Part of ISSN: 0905-6157
Contributors: Mikaïl Berdi; Blandine de Lauzon-Guillain; Anne Forhan; Florence Anne Castelli; François Fenaille; Marie-Aline Charles; Barbara Heude; Christophe Junot; Karine Adel-Patient; the EDEN Mother-Child Cohort Study Group
Source: Self-asserted source
Florence Castelli

Deep analysis of immune response and metabolic signature in children with food protein induced enterocolitis to cow’s milk

Clinical and Translational Allergy
2018-12 | Journal article
Part of ISSN: 2045-7022
Contributors: Karine Adel-Patient; Guillaume Lezmi; Florence Anne Castelli; Sibylle Blanc; Hervé Bernard; Pascale Soulaines; Pascale Dumond; Sandrine Ah-Leung; Florence Lageix; Delphine de Boissieu et al.
Source: Self-asserted source
Florence Castelli

A novel subfamily of bacterial AAT-fold basic amino acid decarboxylases and functional characterization of its first representative: Pseudomonas aeruginosa LdcA

Genome Biology and Evolution
2018-10-13 | Journal article
Part of ISSN: 1759-6653
Contributors: Diego Carriel; Pierre Simon Garcia; Florence Castelli; Patricia Lamourette; François Fenaille; Céline Brochier-Armanet; Sylvie Elsen; Irina Gutsche
Source: Self-asserted source
Florence Castelli

Low-Protein Diet Induces IRE1α-Dependent Anticancer Immunosurveillance

Cell Metabolism
2018-04 | Journal article
Part of ISSN: 1550-4131
Contributors: Camila Rubio-Patiño; Jozef P. Bossowski; Gian Marco De Donatis; Laura Mondragón; Elodie Villa; Lazaro E. Aira; Johanna Chiche; Rana Mhaidly; Cynthia Lebeaupin; Sandrine Marchetti et al.
Source: Self-asserted source
Florence Castelli

Isocitrate dehydrogenase 1 mutations prime the all-trans retinoic acid myeloid differentiation pathway in acute myeloid leukemia

Journal of Experimental Medicine
2016-04-04 | Journal article
Part of ISSN: 0022-1007
Part of ISSN: 1540-9538
Contributors: Héléna Boutzen; Estelle Saland; Clément Larrue; Fabienne de Toni; Lara Gales; Florence A. Castelli; Mathilde Cathebas; Sonia Zaghdoudi; Lucille Stuani; Tony Kaoma et al.
Source: Self-asserted source
Florence Castelli

The Tumor Antigen Cyclin B1 Hosts Multiple CD4 T Cell Epitopes Differently Recognized by Pre-Existing Naive and Memory Cells in Both Healthy and Cancer Donors

The Journal of Immunology
2015-08-15 | Journal article
Part of ISSN: 0022-1767
Part of ISSN: 1550-6606
Contributors: Claire Chevaleyre; Nadine Benhamouda; Emmanuel Favry; Elizabeth Fabre; Anais Mhoumadi; Hervé Nozach; Elodie Marcon; Guillaume Cosler; Emeline Vinatier; Stephane Oudard et al.
Source: Self-asserted source
Florence Castelli

Bee Venom Phospholipase A2, a Good “Chauffeur” for Delivering Tumor Antigen to the MHC I and MHC II Peptide-Loading Compartments of the Dendritic Cells: The Case of NY-ESO-1

PLoS ONE
2013-06-18 | Journal article
Part of ISSN: 1932-6203
Contributors: Christine Almunia; Marie Bretaudeau; Gerhard Held; Aurélie Babon; Charles Marchetti; Florence Anne Castelli; André Ménez; Bernard Maillere; Daniel Gillet
Source: Self-asserted source
Florence Castelli

Hierarchy of CD4 T Cell Epitopes of the ANRS Lipo5 Synthetic Vaccine Relies on the Frequencies of Pre-Existing Peptide-Specific T Cells in Healthy Donors

The Journal of Immunology
2013-06-01 | Journal article
Part of ISSN: 0022-1767
Part of ISSN: 1550-6606
Contributors: Florence Anne Castelli; Natacha Szely; Alexis Olivain; Nicoletta Casartelli; Caroline Grygar; Aurélie Schneider; Aurore Besse; Yves Levy; Olivier Schwartz; Bernard Maillère
Source: Self-asserted source
Florence Castelli

The Signal Peptide of the Tumor-shared Antigen Midkine Hosts CD4+ T Cell Epitopes

Journal of Biological Chemistry
2013-05 | Journal article
Part of ISSN: 0021-9258
Contributors: Jerome Kerzerho; Aurélie Schneider; Emmanuel Favry; Florence Anne Castelli; Bernard Maillère
Source: Self-asserted source
Florence Castelli

Human CD4 T cell epitopes selective for Vaccinia versus Variola virus

Molecular Immunology
2013-04 | Journal article
Part of ISSN: 0161-5890
Contributors: Alicia Probst; Aurore Besse; Emmanuel Favry; Gilles Imbert; Valérie Tanchou; Florence Anne Castelli; Bernard Maillere
Source: Self-asserted source
Florence Castelli

The Angiogenic Growth Factor and Biomarker Midkine Is a Tumor-Shared Antigen

The Journal of Immunology
2010-07-01 | Journal article
Part of ISSN: 0022-1767
Part of ISSN: 1550-6606
Contributors: Jerome Kerzerho; Olivier Adotevi; Florence A. Castelli; Magalie Dosset; Karine Bernardeau; Natacha Szely; Francois Lang; Eric Tartour; Bernard Maillere
Source: Self-asserted source
Florence Castelli

In vitro human CD4+ T cell response to the vaccinia protective antigens B5R and A33R

Molecular Immunology
2009-04 | Journal article
Part of ISSN: 0161-5890
Contributors: Philemon Sirven; Florence Anne Castelli; Alicia Probst; Natacha Szely; Bernard Maillere
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Florence Castelli

Immunoprevalence of the CD4+T-cell response to HIV Tat and Vpr proteins is provided by clustered and disperse epitopes, respectively

European Journal of Immunology
2008-10 | Journal article
Part of ISSN: 0014-2980
Part of ISSN: 1521-4141
Contributors: Florence A. Castelli; Diane Houitte; Gaetan Munier; Natacha Szely; Alain Lecoq; Jean-Paul Briand; Sylviane Muller; Bernard Maillere
Source: Self-asserted source
Florence Castelli

Gender-Dependent HLA-DR-Restricted Epitopes Identified from Herpes Simplex Virus Type 1 Glycoprotein D

Clinical and Vaccine Immunology
2008-09 | Journal article
Part of ISSN: 1556-6811
Part of ISSN: 1556-679X
Contributors: Xiuli Zhang; Florence A. Castelli; Xiaoming Zhu; Michele Wu; Bernard Maillère; Lbachir BenMohamed
Source: Self-asserted source
Florence Castelli

Cross-Reactive CD4+ T Cells against One Immunodominant Tumor-Derived Epitope in Melanoma Patients

The Journal of Immunology
2007-12-01 | Journal article
Part of ISSN: 0022-1767
Part of ISSN: 1550-6606
Contributors: Pavol Kudela; Bratislav Janjic; Julien Fourcade; Florence Castelli; Pedro Andrade; John M. Kirkwood; Talal El-Hefnawy; Massimo Amicosante; Bernard Maillere; Hassane M. Zarour
Source: Self-asserted source
Florence Castelli

Differential capacity of T cell priming in naive donors of promiscuous CD4+ T cell epitopes of HCV NS3 and Core proteins

European Journal of Immunology
2007-06 | Journal article
Part of ISSN: 0014-2980
Part of ISSN: 1521-4141
Contributors: Florence A. Castelli; Mélanie Leleu; Sandra Pouvelle-Moratille; Sandrine Farci; Hassane M. Zarour; Muriel Andrieu; Claude Auriault; André Ménez; Bertrand Georges; Bernard Maillere
Source: Self-asserted source
Florence Castelli

Selective identification of HLA-DP4 binding T cell epitopes encoded by the MAGE-A gene family

Cancer Immunology, Immunotherapy
2007-06 | Journal article
Part of ISSN: 0340-7004
Part of ISSN: 1432-0851
Contributors: Xiao-Fei Wang; William M. Cohen; Florence A. Castelli; Christine Almunia; Bernard Lethé; Sandra Pouvelle-Moratille; Gaetan Munier; Dominique Charron; André Ménez; Hassan M. Zarour et al.
Source: Self-asserted source
Florence Castelli

Determination of a HLA II Promiscuous Peptide Cocktail as Potential Vaccine Against EBV Latency II Malignancies

Journal of Immunotherapy
2007-02 | Journal article
Part of ISSN: 1524-9557
Contributors: Stéphane Depil; Olivier Moralès; Florence A. Castelli; Nadira Delhem; Violaine François; Bertrand Georges; Françoise Dufossé; Franck Morschhauser; Juergen Hammer; Bernard Maillère et al.
Source: Self-asserted source
Florence Castelli
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