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Uncertainty quantification of reference-based cellular deconvolution algorithms

Epigenetics
2023-12-31 | Journal article
DOI: 10.1080/15592294.2022.2137659
Contributors: Dorothea Seiler Vellame; Gemma Shireby; Ailsa MacCalman; Emma L Dempster; Joe Burrage; Tyler Gorrie-Stone; Leonard S Schalkwyk; Jonathan Mill; Eilis Hannon
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DNA methylation signatures of Alzheimer’s disease neuropathology in the cortex are primarily driven by variation in non-neuronal cell-types

Nature Communications
2022-09-24 | Journal article
DOI: 10.1038/s41467-022-33394-7
Contributors: Gemma Shireby; Emma L. Dempster; Stefania Policicchio; Rebecca G. Smith; Ehsan Pishva; Barry Chioza; Jonathan P. Davies; Joe Burrage; Katie Lunnon; Dorothea Seiler Vellame et al.
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Characterizing the properties of bisulfite sequencing data: maximizing power and sensitivity to identify between-group differences in DNA methylation

2021-01-23 | Preprint
DOI: 10.1101/2021.01.22.427791
Contributors: Dorothea Seiler Vellame; Isabel Castanho; Aisha Dahir; Jonathan Mill; Eilis Hannon
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