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Scopus Author ID: 36996621300

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Employment (1)

Massachusetts General Hospital/Harvard Medical School: Boston, Massachusetts, US

2018 to present | Graduate Assistant (Pathology)
Employment
Source: Self-asserted source
Derek Oakley

Funding (1)

Modifiers of Age of Onset in ALS Studied Using Patient iPS-derived Motor Neurons

2011-03-01 to 2013-02-28 | Grant
National Institute on Aging (Baltimore, US)
URL: https://app.dimensions.ai/details/grant/grant.2357966
GRANT_NUMBER: F30AG039238
Source: Self-asserted source
Derek Oakley via DimensionsWizard

Works (24)

β-Amyloid species production and tau phosphorylation in iPSC-neurons with reference to neuropathologically characterized matched donor brains

Journal of Neuropathology & Experimental Neurology
2024-09-01 | Journal article
DOI: 10.1093/jnen/nlae053
Contributors: Derek H Oakley; Mirra Chung; Sara Abrha; Bradley T Hyman; Matthew P Frosch
Source: check_circle
Crossref

A correlation map of genome-wide DNA methylation patterns between paired human brain and buccal samples

2021-12-09 | Preprint
DOI: 10.1101/2021.12.09.471962
Contributors: Yasmine Sommerer; Olena Ohlei; Valerija Dobricic; Derek H. Oakley; Tanja Wesse; Sanaz Sedghpour Sabet; Ilja Demuth; Andre Franke; Bradley T. Hyman; Christina M. Lill et al.
Source: check_circle
Crossref

Continuous Monitoring of Tau-Induced Neurotoxicity in Patient-Derived iPSC-Neurons

The Journal of Neuroscience
2021-05-12 | Journal article
DOI: 10.1523/JNEUROSCI.2590-20.2021
Contributors: Derek H. Oakley; Naomi Klickstein; Caitlin Commins; Mirra Chung; Simon Dujardin; Rachel E. Bennett; Bradley T. Hyman; Matthew P. Frosch
Source: check_circle
Crossref

Kinetics of tau aggregation reveals patient-specific tau characteristics among Alzheimer’s cases

Brain Communications
2021-04-05 | Journal article
DOI: 10.1093/braincomms/fcab096
Contributors: Tarun V Kamath; Naomi Klickstein; Caitlin Commins; Analiese R Fernandes; Derek H Oakley; Matthew P Frosch; Bradley T Hyman; Simon Dujardin
Source: check_circle
Crossref

SOD1 Suppression with Adeno-Associated Virus and MicroRNA in Familial ALS

New England Journal of Medicine
2020-07-09 | Journal article
DOI: 10.1056/nejmoa2005056
Part of ISSN: 0028-4793
Part of ISSN: 1533-4406
Source: Self-asserted source
Derek Oakley

The Alzheimer Disease-Causing Presenilin-1 L435F Mutation Causes Increased Production of Soluble Aβ43 Species in Patient-Derived iPSC-Neurons, Closely Mimicking Matched Patient Brain Tissue

Journal of Neuropathology & Experimental Neurology
2020-06-01 | Journal article
DOI: 10.1093/jnen/nlaa025
Contributors: Derek H Oakley; Mirra Chung; Naomi Klickstein; Caitlin Commins; Bradley T Hyman; Matthew P Frosch
Source: check_circle
Crossref

Case 23-2019: A 52-year-old man with fever, cough, and hypoxemia

New England Journal of Medicine
2019 | Journal article
DOI: 10.1056/NEJMcpc1900598
EID:

2-s2.0-85069933837

Part of ISBN:

15334406 00284793
Contributors: Hardin, C.C.; Malhotra, R.; Petranović, M.; Klassen, S.; Mihatov, N.; Oakley, D.H.
Source: Self-asserted source
Derek Oakley via Scopus - Elsevier

Spinal cord α-synuclein deposition associated with myoclonus in patients with MSA-C

Neurology
2019 | Journal article
DOI: 10.1212/WNL.0000000000007949
EID:

2-s2.0-85068057321

Part of ISBN:

1526632X 00283878
Contributors: Hwang, J.; Bank, A.M.; Mortazavi, F.; Oakley, D.H.; Frosch, M.P.; Schmahmann, J.D.
Source: Self-asserted source
Derek Oakley via Scopus - Elsevier

Wide Range of Clinical Outcomes in Patients with Gliomatosis Cerebri Growth Pattern: A Clinical, Radiographic, and Histopathologic Study

Oncologist
2019 | Journal article
DOI: 10.1634/theoncologist.2018-0086
EID:

2-s2.0-85054809794

Part of ISBN:

1549490X 10837159
Contributors: Ly, K.I.; Oakley, D.H.; Pine, A.B.; Frosch, M.P.; Chiou, S.H.; Betensky, R.A.; Pomerantz, S.R.; Hochberg, F.H.; Batchelor, T.T.; Cahill, D.P. et al.
Source: Self-asserted source
Derek Oakley via Scopus - Elsevier

Synaptic tau seeding precedes tau pathology in human Alzheimer's disease brain

Frontiers in Neuroscience
2018 | Journal article
DOI: 10.3389/fnins.2018.00267
EID:

2-s2.0-85046081221

Part of ISBN:

1662453X 16624548
Contributors: DeVos, S.L.; Corjuc, B.T.; Oakley, D.H.; Nobuhara, C.K.; Bannon, R.N.; Chase, A.; Commins, C.; Gonzalez, J.A.; Dooley, P.M.; Frosch, M.P. et al.
Source: Self-asserted source
Derek Oakley via Scopus - Elsevier

The role of microglia in processing and spreading of bioactive tau seeds in Alzheimer's disease 11 Medical and Health Sciences 1109 Neurosciences

Journal of Neuroinflammation
2018 | Journal article
DOI: 10.1186/s12974-018-1309-z
EID:

2-s2.0-85053512508

Part of ISBN:

17422094
Contributors: Hopp, S.C.; Lin, Y.; Oakley, D.; Roe, A.D.; Devos, S.L.; Hanlon, D.; Hyman, B.T.
Source: Self-asserted source
Derek Oakley via Scopus - Elsevier

Case 13-2017: A 41-Year-old man with hearing loss, seizures, weakness, and cognitive decline

New England Journal of Medicine
2017 | Journal article
DOI: 10.1056/NEJMcpc1616022
EID:

2-s2.0-85018991352

Part of ISBN:

15334406 00284793
Contributors: Reda, H.M.; Copen, W.A.; Karaa, A.; Oakley, D.H.
Source: Self-asserted source
Derek Oakley via Scopus - Elsevier

Pathological correlations of [F-18]-AV-1451 imaging in non-alzheimer tauopathies

Annals of Neurology
2017 | Journal article
DOI: 10.1002/ana.24844
EID:

2-s2.0-85010457809

Part of ISBN:

15318249 03645134
Contributors: Marquié, M.; Normandin, M.D.; Meltzer, A.C.; Siao Tick Chong, M.; Andrea, N.V.; Antón-Fernández, A.; Klunk, W.E.; Mathis, C.A.; Ikonomovic, M.D.; Debnath, M. et al.
Source: Self-asserted source
Derek Oakley via Scopus - Elsevier

Case 32-2016: A 20-year-old man with gynecomastia

New England Journal of Medicine
2016 | Journal article
DOI: 10.1056/NEJMcpc1610098
EID:

2-s2.0-84992052035

Part of ISBN:

15334406 00284793
Contributors: MacDonald, S.M.; Rapalino, O.; Sherry, N.A.; Cohen, A.B.; Ebb, D.H.; Tarbell, N.J.; Oakley, D.H.
Source: Self-asserted source
Derek Oakley via Scopus - Elsevier

Directly visualized glioblastoma-derived extracellular vesicles transfer RNA to microglia/macrophages in the brain

Neuro-Oncology
2016 | Journal article
DOI: 10.1093/neuonc/nov244
EID:

2-s2.0-84960442277

Part of ISBN:

15235866 15228517
Contributors: Van Der Vos, K.E.; Abels, E.R.; Zhang, X.; Lai, C.; Carrizosa, E.; Oakley, D.; Prabhakar, S.; Mardini, O.; Crommentuijn, M.H.W.; Skog, J. et al.
Source: Self-asserted source
Derek Oakley via Scopus - Elsevier

Novel Compound Heterozygous Mutations Expand the Recognized Phenotypes of FARS2 -Linked Disease

Journal of Child Neurology
2016 | Journal article
DOI: 10.1177/0883073816643402
EID:

2-s2.0-84978196195

Part of ISBN:

17088283 08830738
Contributors: Walker, M.A.; Mohler, K.P.; Hopkins, K.W.; Oakley, D.H.; Sweetser, D.A.; Ibba, M.; Frosch, M.P.; Thibert, R.L.
Source: Self-asserted source
Derek Oakley via Scopus - Elsevier

Protein Prenylation Constitutes an Endogenous Brake on Axonal Growth

Cell reports
2016 | Journal article
DOI: 10.1016/j.celrep.2016.06.013
EID:

2-s2.0-84991765583

Part of ISBN:

22111247
Contributors: Li, H.; Kuwajima, T.; Oakley, D.; Nikulina, E.; Hou, J.; Yang, W.S.; Lowry, E.R.; Lamas, N.J.; Amoroso, M.W.; Croft, G.F. et al.
Source: Self-asserted source
Derek Oakley via Scopus - Elsevier

A 20-year-old man with back pain and lower extremity weakness

JAMA Neurology
2015 | Journal article
DOI: 10.1001/jamaneurol.2014.3833
EID:

2-s2.0-84926316871

Part of ISBN:

21686149
Contributors: Etherton, M.R.; Neagu, M.R.; Oakley, D.H.; Koch, M.J.; Shin, J.H.; Frosch, M.P.; Berkowitz, A.L.; Dietrich, J.
Source: Self-asserted source
Derek Oakley via Scopus - Elsevier

Erratum: Pathways disrupted in human ALS motor neurons identified through genetic correction of mutant SOD1 (Cell Stem Cell (2014) 14 (781795))

Cell Stem Cell
2014 | Journal article
DOI: 10.1016/j.stem.2014.04.005
EID:

2-s2.0-84902134992

Part of ISBN:

18759777 19345909
Contributors: Kiskinis, E.; Sandoe, J.; Williams, L.A.; Boulting, G.L.; Moccia, R.; Wainger, B.J.; Han, S.; Peng, T.; Thams, S.; Mikkilineni, S. et al.
Source: Self-asserted source
Derek Oakley via Scopus - Elsevier

Pathways disrupted in human ALS motor neurons identified through genetic correction of mutant SOD1

Cell Stem Cell
2014 | Journal article
DOI: 10.1016/j.stem.2014.03.004
EID:

2-s2.0-84902191691

Part of ISBN:

18759777 19345909
Contributors: Kiskinis, E.; Sandoe, J.; Williams, L.A.; Boulting, G.L.; Moccia, R.; Wainger, B.J.; Han, S.; Peng, T.; Thams, S.; Mikkilineni, S. et al.
Source: Self-asserted source
Derek Oakley via Scopus - Elsevier

Stem cells in the nervous system

American Journal of Physical Medicine and Rehabilitation
2014 | Journal article
DOI: 10.1097/PHM.0000000000000111
EID:

2-s2.0-84914810934

Part of ISBN:

15377385 08949115
Contributors: Maldonado-Soto, A.R.; Oakley, D.H.; Wichterle, H.; Stein, J.; Doetsch, F.K.; Henderson, C.E.
Source: Self-asserted source
Derek Oakley via Scopus - Elsevier

Accelerated high-yield generation of limb-innervating motor neurons from human stem cells

Journal of Neuroscience
2013 | Journal article
DOI: 10.1523/JNEUROSCI.0906-12.2013
EID:

2-s2.0-84872058490

Part of ISBN:

02706474 15292401
Contributors: Amoroso, M.W.; Croft, G.F.; Williams, D.J.; O'Keeffe, S.; Carrasco, M.A.; Davis, A.R.; Roybon, L.; Oakley, D.H.; Maniatis, T.; Henderson, C.E. et al.
Source: Self-asserted source
Derek Oakley via Scopus - Elsevier

A functionally characterized test set of human induced pluripotent stem cells

Nature Biotechnology
2011 | Journal article
DOI: 10.1038/nbt.1783
EID:

2-s2.0-79551665440

Part of ISBN:

10870156 15461696
Contributors: Boulting, G.L.; Kiskinis, E.; Croft, G.F.; Amoroso, M.W.; Oakley, D.H.; Wainger, B.J.; Williams, D.J.; Kahler, D.J.; Yamaki, M.; Davidow, L. et al.
Source: Self-asserted source
Derek Oakley via Scopus - Elsevier

Reference maps of human es and ips cell variation enable high-throughput characterization of pluripotent cell lines

Cell
2011 | Journal article
DOI: 10.1016/j.cell.2010.12.032
EID:

2-s2.0-79551677421

Part of ISBN:

00928674
Contributors: Bock, C.; Kiskinis, E.; Verstappen, G.; Gu, H.; Boulting, G.; Smith, Z.D.; Ziller, M.; Croft, G.F.; Amoroso, M.W.; Oakley, D.H. et al.
Source: Self-asserted source
Derek Oakley via Scopus - Elsevier

Peer review (2 reviews for 1 publication/grant)

Review activity for Journal of neuropathology and experimental neurology. (2)
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