Personal information

Websites & social links

Liu Research Group

Other IDs

ResearcherID: O-4425-2014

Keywords

Non-canonical amino acids, Genetic code expansion, Click chemistry, Phage display, epigenetics, posttranslational modifications, Protein engineering, Drug discovery, Chemical biology

Countries

United States

Activities

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Employment (6)

Texas A&M University: College Station, TX, US

2022-09-01 to present | Harry E. Bovay, Jr. Endowed Chair and Professor in Chemistry (Chemistry)
Employment
Source: Self-asserted source
wenshe Liu

Texas A&M University: College Station, TX, US

2018-09-01 to 2022-08-31 | Gradipore Chair and Professor in Chemistry (Chemistry)
Employment
Source: Self-asserted source
wenshe Liu

Texas A&M University: College Station, TX, US

2016-09-01 to 2018-08-31 | Emile and Marta Schweikert Professor of Chemistry (Chemistry)
Employment
Source: Self-asserted source
wenshe Liu

Texas A&M University: College Station, TX, US

2014-08-01 to 2016-08-31 | Emile & Marta Schweikert Associate Professor (Chemistry)
Employment
Source: Self-asserted source
wenshe Liu

Texas A&M University: College Station, TX, US

2013-09-01 to 2014-07-31 | Associate Professor (Chemistry)
Employment
Source: Self-asserted source
wenshe Liu

Texas A&M University: College Station, TX, US

2007-08-01 to 2013-08-31 | Assistant Professor (Chemistry)
Employment
Source: Self-asserted source
wenshe Liu

Education and qualifications (3)

The Scripps Research Institute: La Jolla, CA, US

2005-07-01 to 2007-07-31 | Postdoc (Chemistry)
Education
Source: Self-asserted source
wenshe Liu

University of California-Davis: Davis, CA, US

2000-09-01 to 2005-06-31 | PhD (Chemistry)
Education
Source: Self-asserted source
wenshe Liu

Peking University: Beijing, CN

1996-09-01 to 2000-09-15 | BS (Chemistry)
Education
Source: Self-asserted source
wenshe Liu

Professional activities (10)

Protein Society: Bethesda, MD, US

Service
Source: Self-asserted source
wenshe Liu

American Society for Biochemistry and Molecular Biology: Rockville, MD, US

Service
Source: Self-asserted source
wenshe Liu

American Peptide Society: Columbus, OH, US

Service
Source: Self-asserted source
wenshe Liu

American Chemical Society: Washington, DC, US

Membership
Source: Self-asserted source
wenshe Liu

American Association for Cancer Research: PA, PA, US

2023-04-24 to present
Membership
Source: Self-asserted source
wenshe Liu

Chinese Chemistry and Chemical Biology Professor Association: Atlanta, US

2007 to present
Membership
Source: Self-asserted source
wenshe Liu

Texas A&M University: College Station, TX, US

2021 | Texas A&M EDGES Fellow (Chemistry)
Distinction
Source: Self-asserted source
wenshe Liu

Texas A&M University: College Station, TX, US

2018 | Presidential Impact Fellow (Chemistry)
Distinction
Source: Self-asserted source
wenshe Liu

Chinese Chemistry and Chemical Biology Professor Association: Atlanta, US

2016 | Biomatrik Distinguished Professor Award
Distinction
Source: Self-asserted source
wenshe Liu

National Science Foundation: Washington DC, US

2012 | NSF CAREER Award
Distinction
Source: Self-asserted source
wenshe Liu

Funding (13)

TREC Major Instrument Award: The Acquisition of an Instrument Suite to Set Up a High-Throughput Screening Core at Texas A&M University

2023-09 to 2025-08 | Grant
Cancer Prevention and Research Institute of Texas (Austin, Texas, US)
GRANT_NUMBER:

RP230449
Source: Self-asserted source
wenshe Liu

VaXCelerate 3.0: a scalable and efficient self-assembling vaccine platform to enable rapid development of U.S. military vaccines

2023-09 to 2025-08 | Grant
U.S. Department of Defense (DC, DC, US)
GRANT_NUMBER:

HT94252310586
Source: Self-asserted source
wenshe Liu

The Development of Reversible Chemogenetic Switches for Chimeric Antigen Receptor T Cell Therapy

2023-02-15 to present | Grant
Cancer Prevention and Research Institute of Texas (Austin, US)
URL: https://app.dimensions.ai/details/grant/grant.13250281
GRANT_NUMBER: RP230345
Source: Self-asserted source
wenshe Liu via DimensionsWizard

Development of fluorogenic and chemiluminogenic main protease substrates for cellular and in vivo imaging of SARS-CoV-2

2022-05-01 to 2024-02-29 | Grant
National Institute of Biomedical Imaging and Bioengineering (Bethesda, US)
URL: https://app.dimensions.ai/details/grant/grant.12885215
GRANT_NUMBER: R21EB032983
Source: Self-asserted source
wenshe Liu via DimensionsWizard

Use of the Noncanonical Amino Acid Mutagenesis Technique in Combination with Other Approaches to Study Functions of Posttranslational Lysine Modifications in Proteins

2022-04-01 to 2027-03-31 | Grant
National Institute of General Medical Sciences (Bethesda, US)
URL: https://app.dimensions.ai/details/grant/grant.12852825
GRANT_NUMBER: R35GM145351
Source: Self-asserted source
wenshe Liu via DimensionsWizard

Targeting the ENL YEATS domain for the development of anti-leukemia agents

2021-12-03 to 2023-11-30 | Grant
National Cancer Institute (Bethesda, US)
URL: https://app.dimensions.ai/details/grant/grant.10003600
GRANT_NUMBER: R21CA267512
Source: Self-asserted source
wenshe Liu via DimensionsWizard

STTR Phase I: Discovery and Development of Macrocyclic Peptide Inhibitors of SARS-COV-2 Spike Protein for the Treatment of COVID-19

2021-07-01 to 2022-07-31 | Grant
Directorate for Technology, Innovation and Partnerships (Alexandria, US)
URL: https://app.dimensions.ai/details/grant/grant.9705482
GRANT_NUMBER: 2111297
Source: Self-asserted source
wenshe Liu via DimensionsWizard

The Identification and Characterization of SARS-CoV-2 Main Protease Inhibitors with Novel Chemical Entities

2021-06 to 2024-05 | Grant
Welch Foundation (Houston, Texas, US)
GRANT_NUMBER:

A-1715
Source: Self-asserted source
wenshe Liu
grade
Preferred source (of 3)‎

Develop General Methods for the Synthesis of Proteins with Posttranslational Lysine Modifications

2019-01-15 to 2022-11-30 | Grant
National Institute of General Medical Sciences (Bethesda, US)
URL: https://app.dimensions.ai/details/grant/grant.8383856
GRANT_NUMBER: R01GM127575
Source: Self-asserted source
wenshe Liu via DimensionsWizard

The preparation of novel phage-displayed macrocyclic peptide libraries for the identification of anti-cancer agents

2017-09 to 2019-08 | Grant
Cancer Prevention and Research Institute of Texas (TX, TX, US)
GRANT_NUMBER:

RP170797
Source: Self-asserted source
wenshe Liu
grade
Preferred source (of 2)‎

Studying Reversible Histone Acylations in Nucleosome Contexts

2016-12 to 2021-11 | Grant
National Institute of General Medical Sciences (MD, MD, US)
GRANT_NUMBER: R01GM121584
Source: Self-asserted source
wenshe Liu
grade
Preferred source (of 2)‎

CAREER: Site-specific dual-labeling of a protein through two genetically incorporated noncanonical amino acids

2012-04-01 to 2017-03-31 | Grant
National Science Foundation (n/a, US)
GRANT_NUMBER: 1148684
GRANT_NUMBER: 1148684
Source: Self-asserted source
wenshe Liu via DimensionsWizard

Phage Display with Two Genetically Incorporated Noncanonical Amino Acids

2011-07 to 2017-04 | Grant
National Cancer Institute (Bethesda, US)
GRANT_NUMBER: R01CA161158
Source: Self-asserted source
wenshe Liu
grade
Preferred source (of 3)‎

Works (50 of 124)

Items per page:
Page 1 of 3

2-Cyanopyrimidine-Containing Molecules for N-Terminal Selective Cyclization of Phage-Displayed Peptides

ACS Chemical Biology
2025-01-17 | Journal article
DOI: 10.1021/acschembio.4c00725
Contributors: J. Trae Hampton; Connor R. Dobie; Demonta D. Coleman; Moulay I. Cherif; Sukant Das; Wenshe Ray Liu
Source: check_circle
Crossref

Prioritization of Eleven-Nineteen-Leukemia Inhibitors as Orally Available Drug Candidates for Acute Myeloid Leukemia

Journal of Medicinal Chemistry
2024-11-28 | Journal article
DOI: 10.1021/acs.jmedchem.4c01337
Contributors: Xuejiao Shirley Guo; Sandeep Atla; Satyanarayana Nyalata; Yugendar R. Alugubelli; Peng-Hsun Chase Chen; Shiqing Xu; Wenshe Ray Liu
Source: check_circle
Crossref

Computational Model-Assisted Development of a Nonenzymatic Fluorescent Glucose-Sensing Assay

ACS Sensors
2024-11-22 | Journal article
DOI: 10.1021/acssensors.4c02117
Contributors: Lydia Colvin; Diana Al Husseini; Dandan Tu; Darin Dunlap; Tyler Lalonde; Muhammed Üçüncü; Alicia Megia-Fernandez; Mark Bradley; Wenshe Liu; Melissa A. Grunlan et al.
Source: check_circle
Crossref

Directed Evolution of Candidatus Methanomethylophilus alvus Pyrrolysyl-tRNA Synthetase for the Genetic Incorporation of Two Different Noncanonical Amino Acids in One Protein

ACS Bio & Med Chem Au
2024-10-16 | Journal article
DOI: 10.1021/acsbiomedchemau.4c00028
Contributors: Chia-Chuan D. Cho; Waye Michelle Leeuwon; Wenshe Ray Liu
Source: check_circle
Crossref

Diversification of Phage-Displayed Peptide Libraries with Noncanonical Amino Acid Mutagenesis and Chemical Modification

Chemical Reviews
2024-05-08 | Journal article
DOI: 10.1021/acs.chemrev.4c00004
Contributors: J. Trae Hampton; Wenshe Ray Liu
Source: check_circle
Crossref

Leveraging a Phage-Encoded Noncanonical Amino Acid: A Novel Pathway to Potent and Selective Epigenetic Reader Protein Inhibitors

ACS Central Science
2024-02-27 | Journal article
DOI: 10.1021/acscentsci.3c01419
Contributors: Peng-Hsun Chase Chen; Xuejiao Shirley Guo; Hanyuan Eric Zhang; Gopal K. Dubey; Zhi Zachary Geng; Carol A. Fierke; Shiqing Xu; J. Trae Hampton; Wenshe Ray Liu
Source: check_circle
Crossref

BRD4354 Is a Potent Covalent Inhibitor against the SARS-CoV-2 Main Protease

Biochemistry
2024-02-08 | Journal article
DOI: 10.1021/acs.biochem.3c00685
Contributors: Yan J. Sheng; Syuan-Ting A. Kuo; Tingyuan Yang; Hanyuan E. Zhang; David H. Russell; Xin Yan; Shiqing Xu; Wenshe R. Liu; Carol A. Fierke
Source: check_circle
Crossref

A Systematic Survey of Reversibly Covalent Dipeptidyl Inhibitors of the SARS-CoV-2 Main Protease

Journal of Medicinal Chemistry
2023-08-24 | Journal article | Author
DOI: 10.1021/acs.jmedchem.3c00221
Part of ISSN: 0022-2623
Part of ISSN: 1520-4804
Contributors: Zhi Zachary Geng; Sandeep Atla; Namir Shaabani; Veerabhadra Vulupala; Kai Yang; Yugendar R. Alugubelli; Kaustav Khatua; Peng-Hsun Chen; Jing Xiao; Lauren R. Blankenship et al.
Source: Self-asserted source
wenshe Liu

An amber-encoding helper phage for more efficient phage display of noncanonical amino acids

Nucleic Acids Research
2023-07-21 | Journal article
DOI: 10.1093/nar/gkad488
Contributors: Joshua Trae Hampton; Chia-Chuan Dean Cho; Demonta D Coleman; Zhi Zachary Geng; Peng-Hsun Chase Chen; Gopal K Dubey; Lauralee D Sylvain; Shiqing Xu; Wenshe Ray Liu
Source: check_circle
Crossref

An Azapeptide Platform in Conjunction with Covalent Warheads to Uncover High-Potency Inhibitors for SARS-CoV-2 Main Protease

2023-04 | Preprint
DOI: 10.1101/2023.04.11.536467
PPR: PPR644778
Contributors: Khatua K; Alugubelli YR; Yang KS; Vulupala VR; Blankenship LR; Coleman DD; Atla S; Chaki SP; Geng ZZ; Ma XR et al.
Source: Self-asserted source
wenshe Liu via Europe PubMed Central

A Novel Y-Shaped, S–O–N–O–S-Bridged Cross-Link between Three Residues C22, C44, and K61 Is Frequently Observed in the SARS-CoV-2 Main Protease

ACS Chemical Biology
2023-03-17 | Journal article
DOI: 10.1021/acschembio.2c00695
Contributors: Kai S. Yang; Lauren R. Blankenship; Syuan-Ting Alex Kuo; Yan J. Sheng; Pingwei Li; Carol A. Fierke; David H. Russell; Xin Yan; Shiqing Xu; Wenshe Ray Liu
Source: check_circle
Crossref

Phage-Assisted, Active Site-Directed Ligand Evolution with a Genetically EncodedNε-Butyryl-L-Lysine to Identify a Cellularly Potent and Selective Inhibitor for the ENL YEATS Domain as an Anti-Leukemia Agent

2023-01-09 | Preprint
DOI: 10.1101/2023.01.08.523168
Contributors: Peng-Hsun Chase Chen; Xuejiao Shirley Guo; Hanyuan Eric Zhang; Zhi Zachary Geng; Gopal K. Dubey; Carol A. Fierke; Shiqing Xu; Wenshe Ray Liu
Source: check_circle
Crossref

Protein Synthesis via Activated Cysteine-Directed Protein Ligation

Methods in Molecular Biology
2022 | Book chapter
DOI: 10.1007/978-1-0716-2489-0_11
Part of ISBN: 9781071624883
Part of ISBN: 9781071624890
Part of ISSN: 1064-3745
Part of ISSN: 1940-6029
Contributors: Ge Yu; Yuchen Qiao; Lauren R. Blankenship; Wenshe Ray Liu
Source: Self-asserted source
wenshe Liu

Repurposing Halicin as a potent covalent inhibitor for the SARS-CoV-2 main protease

Current Research in Chemical Biology
2022 | Journal article
DOI: 10.1016/j.crchbi.2022.100025
Contributors: Kai S. Yang; Syuan-Ting Alex Kuo; Lauren R. Blankenship; Zhi Zachary Geng; Shuhua G. Li; David H. Russell; Xin Yan; Shiqing Xu; Wenshe Ray Liu
Source: check_circle
Crossref

<scp>Phage‐assisted</scp>, active <scp>site‐directed</scp> ligand evolution of a potent and selective histone deacetylase 8 inhibitor

Protein Science
2022-12 | Journal article | Author
DOI: 10.1002/pro.4512
Part of ISSN: 0961-8368
Part of ISSN: 1469-896X
Contributors: Jared Morse; Yan J. Sheng; Joshua Hampton; Lauralee D. Sylvain; Sukant Das; Yugendar R. Alugubelli; Peng-Hsun Chen; Kai Yang; Shiqing Xu; Carol A. Fierke et al.
Source: Self-asserted source
wenshe Liu

The Prioritization of Eleven-Nineteen-Leukemia Inhibitors as Potential Drug Candidates to Treat Acute Myeloid Leukemia

2022-12-07 | Preprint | Author
DOI: 10.1101/2022.12.07.519474
Contributors: Xuejiao Shirley Guo; Peng-Hsun Chen; Shiqing Xu; wenshe Liu
Source: Self-asserted source
wenshe Liu
grade
Preferred source (of 2)‎

A multi-pronged evaluation of aldehyde-based tripeptidyl main protease inhibitors as SARS-CoV-2 antivirals

European Journal of Medicinal Chemistry
2022-10 | Journal article
DOI: 10.1016/j.ejmech.2022.114570
Part of ISSN: 0223-5234
Contributors: Yuying Ma; Kai S. Yang; Zhi Zachary Geng; Yugendar R. Alugubelli; Namir Shaabani; Erol C. Vatansever; Xinyu R. Ma; Chia-Chuan Cho; Kaustav Khatua; Jing Xiao et al.
Source: Self-asserted source
wenshe Liu

A systematic exploration of boceprevir-based main protease inhibitors as SARS-CoV-2 antivirals

European Journal of Medicinal Chemistry
2022-10 | Journal article | Author
DOI: 10.1016/j.ejmech.2022.114596
Part of ISSN: 0223-5234
Contributors: Yugendar R. Alugubelli; Zhi Zachary Geng; Kai S. Yang; Namir Shaabani; Kaustav Khatua; Xinyu R. Ma; Erol C. Vatansever; Chia-Chuan Cho; Yuying Ma; Jing Xiao et al.
Source: Self-asserted source
wenshe Liu

Novel Regioselective Approach to Cyclize Phage-Displayed Peptides in Combination with Epitope-Directed Selection to Identify a Potent Neutralizing Macrocyclic Peptide for SARS-CoV-2

ACS Chemical Biology
2022-10-21 | Journal article
DOI: 10.1021/acschembio.2c00565
Contributors: J. Trae Hampton; Tyler J. Lalonde; Jeffery M. Tharp; Yadagiri Kurra; Yugendar R. Alugubelli; Christopher M. Roundy; Gabriel L. Hamer; Shiqing Xu; Wenshe Ray Liu
Source: check_circle
Crossref

Resveratrol Binds Nuclear Receptor 4A1 (NR4A1) and Acts as an NR4A1 Antagonist in Lung Cancer Cells

Molecular Pharmacology
2022-08 | Journal article
DOI: 10.1124/molpharm.121.000481
Part of ISSN: 0026-895X
Part of ISSN: 1521-0111
Contributors: Lei Zhang; Greg Martin; Kumaravel Mohankumar; Joshua Trae Hampton; Wenshe Ray Liu; Stephen Safe
Source: Self-asserted source
wenshe Liu

Evolutionary and Structural Insights about Potential SARS-CoV-2 Evasion of Nirmatrelvir

Journal of Medicinal Chemistry
2022-07-14 | Journal article
DOI: 10.1021/acs.jmedchem.2c00404
Contributors: Kai S. Yang; Sunshine Z. Leeuwon; Shiqing Xu; Wenshe Ray Liu
Source: check_circle
Crossref

Taf2 mediates DNA binding of Taf14

Nature Communications
2022-06-08 | Journal article | Author
DOI: 10.1038/s41467-022-30937-w
Part of ISSN: 2041-1723
Contributors: Brianna J. Klein; Jordan T. Feigerle; Jibo Zhang; CHRISTOPHER EBMEIER; Lixin Fan; Rohit K. Singh; Wesley W. Wang; Lauren R. Schmitt; Thomas Lee; Kirk C. Hansen et al.
Source: Self-asserted source
wenshe Liu

Accurate Mass Identification of an Interfering Water Adduct and Strategies in Development and Validation of an LC-MS/MS Method for Quantification of MPI8, a Potent SARS-CoV-2 Main Protease Inhibitor, in Rat Plasma in Pharmacokinetic Studies

Pharmaceuticals
2022-05-27 | Journal article
DOI: 10.3390/ph15060676
Part of ISSN: 1424-8247
Contributors: Yang Wang; Huan Xie; Yugendar R. Alugubelli; Yuying Ma; Shiqing Xu; Jing Ma; Wenshe R. Liu; Dong Liang
Source: Self-asserted source
wenshe Liu

A Designed, Highly Efficient Pyrrolysyl-tRNA Synthetase Mutant Binds o-Chlorophenylalanine Using Two Halogen Bonds

Journal of Molecular Biology
2022-04 | Journal article
DOI: 10.1016/j.jmb.2022.167534
Part of ISSN: 0022-2836
Contributors: Erol C. Vatansever; Kai S. Yang; Zhi Zachary Geng; Yuchen Qiao; Pingwei Li; Shiqing Xu; Wenshe Ray Liu
Source: Self-asserted source
wenshe Liu

The Pyrrolysyl-tRNA Synthetase Activity can be Improved by a P188 Mutation that Stabilizes the Full-Length Enzyme

Journal of Molecular Biology
2022-04 | Journal article
DOI: 10.1016/j.jmb.2022.167453
Part of ISSN: 0022-2836
Contributors: Chia-Chuan Cho; Lauren R. Blankenship; Xinyu Ma; Shiqing Xu; Wenshe Liu
Source: Self-asserted source
wenshe Liu

A Reversible Chemogenetic Switch for Chimeric Antigen Receptor T Cells**

Angewandte Chemie International Edition
2022-03 | Journal article
DOI: 10.1002/anie.202109550
Contributors: Wenyue Cao; Zhi Zachary Geng; Na Wang; Quan Pan; Shaodong Guo; Shiqing Xu; Jianfeng Zhou; Wenshe Ray Liu
Source: check_circle
Crossref

Evaluation of SARS-CoV-2 Main Protease Inhibitors Using a Novel Cell-Based Assay

ACS Central Science
2022-02-23 | Journal article | Author
DOI: 10.1021/acscentsci.1c00910
Part of ISSN: 2374-7943
Part of ISSN: 2374-7951
Contributors: Wenyue Cao; Chia-Chuan Dean Cho; Zhi Zachary Geng; Namir Shaabani; Xinyu R. Ma; Erol C. Vatansever; Yugendar R. Alugubelli; Yuying Ma; Sankar P. Chaki; William H. Ellenburg et al.
Source: Self-asserted source
wenshe Liu

An Enhanced Hybrid Screening Approach to Identify Potent Inhibitors for the SARS-CoV-2 Main Protease From the NCI Compound Library

Frontiers in Chemistry
2022-02-17 | Journal article
DOI: 10.3389/fchem.2022.816576
Part of ISSN: 2296-2646
Contributors: Shuhua G. Li; Kai S. Yang; Lauren R. Blankenship; Chia-Chuan D. Cho; Shiqing Xu; Hongbin Wang; Wenshe Ray Liu
Source: Self-asserted source
wenshe Liu

Drug Repurposing for the SARS‐CoV‐2 Papain‐Like Protease

ChemMedChem
2022-01-05 | Journal article
DOI: 10.1002/cmdc.202100455
Contributors: Chia‐Chuan Cho; Shuhua G. Li; Tyler J. Lalonde; Kai S. Yang; Ge Yu; Yuchen Qiao; Shiqing Xu; Wenshe Ray Liu
Source: check_circle
Crossref

Front Cover: MPI8 is Potent against SARS‐CoV‐2 by Inhibiting Dually and Selectively the SARS‐CoV‐2 Main Protease and the Host Cathepsin L (ChemMedChem 1/2022)

ChemMedChem
2022-01-05 | Journal article
DOI: 10.1002/cmdc.202100769
Contributors: Xinyu R. Ma; Yugendar R. Alugubelli; Yuying Ma; Erol C. Vatansever; Danielle A. Scott; Yuchen Qiao; Ge Yu; Shiqing Xu; Wenshe Ray Liu
Source: check_circle
Crossref

The Construction of a Genetically Encoded, Phage-Displayed Cyclic-Peptide Library

Methods in Molecular Biology
2021 | Book chapter
DOI: 10.1007/978-1-0716-1617-8_17
Part of ISBN: 9781071616161
Part of ISBN: 9781071616178
Part of ISSN: 1064-3745
Part of ISSN: 1940-6029
Contributors: Peng-Hsun Chase Chen; Wenshe Ray Liu
Source: Self-asserted source
wenshe Liu

Zinc thiotropolone combinations as inhibitors of the SARS-CoV-2 main protease

Dalton Transactions
2021 | Journal article
DOI: 10.1039/d1dt02499j
Part of ISSN: 1477-9226
Part of ISSN: 1477-9234
Contributors: Christopher DeLaney; Yan Sheng; D. Chase Pectol; Erol Vantansever; Hanyuan Zhang; Nattamai Bhuvanesh; Isaiah Salas; Wenshe R. Liu; Carol F. Fierke; Marcetta Y. Darensbourg
Source: Self-asserted source
wenshe Liu

Self-Masked Aldehyde Inhibitors: A Novel Strategy for Inhibiting Cysteine Proteases.

Journal of medicinal chemistry
2021-07-21 | Journal article
DOI: 10.1021/acs.jmedchem.1c00628
PMID: 34288674
Source: Self-asserted source
wenshe Liu

Discovery of Selective Small-Molecule Inhibitors for the ENL YEATS Domain.

Journal of medicinal chemistry
2021-07-19 | Journal article
DOI: 10.1021/acs.jmedchem.1c00367
PMID: 34279931
Source: Self-asserted source
wenshe Liu

MPI8 is Potent Against SARS-CoV-2 by Inhibiting Dually and Selectively the SARS-CoV-2 Main Protease and the Host Cathepsin L.

ChemMedChem
2021-07-09 | Journal article
DOI: 10.1002/cmdc.202100456
PMID: 34242492
Source: Self-asserted source
wenshe Liu
grade
Preferred source (of 2)‎

Cellular Activities of SARS-CoV-2 Main Protease Inhibitors Reveal Their Unique Characteristics

[]
2021-06-09 | Preprint
DOI: 10.1101/2021.06.08.447613
Source: Self-asserted source
wenshe Liu

Drug Repurposing for the SARS-CoV-2 Papain-Like Protease

[]
2021-06-06 | Preprint
DOI: 10.1101/2021.06.04.447160
Source: Self-asserted source
wenshe Liu

Site-Specific Conversion of Cysteine in a Protein to Dehydroalanine Using 2-Nitro-5-thiocyanatobenzoic Acid

Molecules
2021-04-29 | Journal article
DOI: 10.3390/molecules26092619
Contributors: Yuchen Qiao; Ge Yu; Sunshine Z. Leeuwon; Wenshe Ray Liu
Source: check_circle
Crossref

Bepridil is potent against SARS-CoV-2 in vitro.

Proceedings of the National Academy of Sciences of the United States of America
2021-03-01 | Journal article
DOI: 10.1073/pnas.2012201118
PMID: 33597253
PMC: PMC7958448
Source: Self-asserted source
wenshe Liu

Site Specific Lysine Acetylation of Histones for Nucleosome Reconstitution using Genetic Code Expansion in Escherichia coli.

Journal of visualized experiments : JoVE
2020-12-26 | Journal article
DOI: 10.3791/62113
PMID: 33427240
Source: Self-asserted source
wenshe Liu

A Quick Route to Multiple Highly Potent SARS-CoV-2 Main Protease Inhibitors

ChemMedChem
2020-12-07 | Journal article
DOI: 10.1002/cmdc.202000924
PMID: 33283984
Source: Self-asserted source
wenshe Liu

The molecular basis of tight nuclear tethering and inactivation of cGAS

Nature
2020-11-26 | Journal article
DOI: 10.1038/s41586-020-2749-z
Contributors: Baoyu Zhao; Pengbiao Xu; Chesley M. Rowlett; Tao Jing; Omkar Shinde; Yuanjiu Lei; A. Phillip West; Wenshe Ray Liu; Pingwei Li
Source: check_circle
Crossref

An optimal "Click" formulation strategy for antibody-drug conjugate synthesis.

Bioorganic & medicinal chemistry
2020-10-06 | Journal article
DOI: 10.1016/j.bmc.2020.115808
PMID: 33071032
Source: Self-asserted source
wenshe Liu

A Speedy Route to Multiple Highly Potent SARS-CoV-2 Main Protease Inhibitors

2020-07-28 | Preprint | Author
DOI: 10.1101/2020.07.28.223784
Contributors: Kai S. Yang; Xinyu R. Ma; Yuying Ma; Yugendar R. Alugubelli; Danielle A. Scott; Erol C. Vatansever; Aleksandra K. Drelich; Banumathi Sankaran; Zhi Z. Geng; Lauren R. Blankenship et al.
Source: Self-asserted source
wenshe Liu

Stepwise Assembly of Turn‐on Fluorescence Sensors in Multicomponent Metal–Organic Frameworks for in Vitro Cyanide Detection

Angewandte Chemie
2020-06-08 | Journal article
DOI: 10.1002/ange.202000702
Contributors: Jialuo Li; Shuai Yuan; Jun‐Sheng Qin; Jiandong Pang; Peng Zhang; Yingmu Zhang; Yanyan Huang; Hannah F. Drake; Wenshe R. Liu; Hong‐Cai Zhou
Source: check_circle
Crossref

Bepridil is potent against SARS-CoV-2 In Vitro

2020-05-23 | Preprint
DOI: 10.1101/2020.05.23.112235
Contributors: Erol C. Vatansever; Kai Yang; Kaci C. Kratch; Aleksandra Drelich; Chia-Chuan Cho; Drake M. Mellott; Shiqing Xu; Chien-Te K. Tseng; Wenshe Ray Liu
Source: check_circle
Crossref

Expressed Protein Ligation without Intein.

Journal of the American Chemical Society
2020-04-02 | Journal article
DOI: 10.1021/jacs.0c00252
PMID: 32212692
Source: Self-asserted source
wenshe Liu
grade
Preferred source (of 2)‎

Stepwise Assembly of Turn-on Fluorescence Sensors in Multicomponent Metal-Organic Frameworks for in Vitro Cyanide Detection.

Angewandte Chemie (International ed. in English)
2020-04-01 | Journal article
DOI: 10.1002/anie.202000702
PMID: 32174003
Source: Self-asserted source
wenshe Liu
grade
Preferred source (of 2)‎

An amber obligate active site-directed ligand evolution technique for phage display.

Nature communications
2020-03-13 | Journal article
DOI: 10.1038/s41467-020-15057-7
PMID: 32170178
PMC: PMC7070036
Source: Self-asserted source
wenshe Liu
grade
Preferred source (of 2)‎

Learning from the Past: Possible Urgent Prevention and Treatment Options for Severe Acute Respiratory Infections Caused by 2019-nCoV.

Chembiochem : a European journal of chemical biology
2020-02-25 | Journal article
DOI: 10.1002/cbic.202000047
PMID: 32022370
PMC: PMC7162020
Source: Self-asserted source
wenshe Liu
grade
Preferred source (of 2)‎
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Peer review (106 reviews for 19 publications/grants)

Review activity for Accounts of chemical research. (1)
Review activity for ACS central science. (4)
Review activity for ACS chemical biology. (14)
Review activity for ACS combinatorial science. (2)
Review activity for ACS infectious diseases. (3)
Review activity for ACS medicinal chemistry letters. (3)
Review activity for ACS nano. (1)
Review activity for ACS synthetic biology. (5)
Review activity for Angewandte Chemie. (6)
Review activity for Biochemistry. (7)
Review activity for Bioconjugate chemistry. (1)
Review activity for Biomacromolecules. (1)
Review activity for ChemBioChem. (6)
Review activity for Chemical reviews. (4)
Review activity for ChemMedChem. (3)
Review activity for Journal of medicinal chemistry. (7)
Review activity for Journal of the American Chemical Society. (33)
Review activity for Nature chemistry. (1)
Review activity for Nature communications (4)
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