Personal information

Streptococcus equi, Streptococcus zooepidemicus, vaccine, diagnostic tests, genomics
United Kingdom

Biography

Dr. Waller's research aims to identify mechanisms that underlie disease processes that can be exploited to improve the health of animals, including humans. His work to develop novel anti-infective agents at British Biotech provided experience of bacterial genetics and product development. Andrew joined the Animal Health Trust in 2003 to study Streptococcus equi and Streptococcus zooepidemicus. His group transformed the understanding of these pathogens and developed new diagnostic tests that permit the eradication of Streptococcus equi from horse populations. The health and welfare benefits of his work were recognised by the British Horse Society in 2012 and the National Equine Forum in 2014. In July 2020, Andrew joined Intervacc AB as Chief Scientific Officer, leading the development of safe and effective vaccines with which to improve animal health. The first of these products, a novel multicomponent subunit vaccine named Strangvacc, which protects up to 95% of horses from strangles, is due to be launched in Europe during 2021. The techniques developed by Dr. Waller's group are also being applied more widely in collaboration with researchers throughout the world to improve the understanding, treatment and prevention of other streptococcal pathogens, including S. canis, S. pyogenes, S. agalactiae and S. gordonii.

Activities

Employment (4)

Intervacc AB: Stockholm, SE

2020-07-01 to present | Chief Scientific Officer
Employment
Source: Self-asserted source
Andrew Waller

Swedish University of Agricultural Sciences: Uppsala, SE

2021-01-01 to 2022-12-31 | Research Scientist (Biomedical Sciences and Veterinary Public Health)
Employment
Source: Self-asserted source
Andrew Waller

Animal Health Trust: Newmarket, Suffolk, GB

2003-06-01 to 2020-06-30 | Head of Bacteriology (Bacteriology)
Employment
Source: Self-asserted source
Andrew Waller

British Biotech Pharmaceuticals Limited: Oxford, Oxfordshire, GB

1996-11-01 to 2003-05-31 | Group Leader Biology (Biology)
Employment
Source: Self-asserted source
Andrew Waller

Education and qualifications (2)

University of York: York, York, GB

1993-10-01 to 1996-09-31 | PhD (Biology)
Education
Source: Self-asserted source
Andrew Waller

University of Bristol: Bristol, Bristol, GB

1990-10-01 to 1993-06-11 | Cellular and Molecular Pathology (Biology)
Education
Source: Self-asserted source
Andrew Waller

Professional activities (6)

Petplan Charitable Trust: London, London, GB

2009 to present | Scientific Advisory Committee
Membership
Source: Self-asserted source
Andrew Waller

University of Northumbria: Newcastle, Northumbria, GB

2007 to present | Visiting Professor
Invited position
Source: Self-asserted source
Andrew Waller

Veterinary Research Club: London, GB

2015 to 2016 | President
Service
Source: Self-asserted source
Andrew Waller

National Equine Forum: London, GB

2014 | Sir Colin Spedding Award (presented by HRH Princess Royal)
Distinction
Source: Self-asserted source
Andrew Waller

British Horse Society: London, GB

2012 | Welfare Award (presented by Martin Clunes)
Distinction
Source: Self-asserted source
Andrew Waller

British Prostate Group: London, GB

1995 | Zeneca Pharma Award
Distinction
Source: Self-asserted source
Andrew Waller

Funding (44)

Understanding the silent carriers of Streptococcus equi: the key to eradicating strangles?

2020-01 to 2023-01 | Grant
Svenska Forskningsrådet Formas (Stockholm, SE)
GRANT_NUMBER:

2019-02127

Source: Self-asserted source
Andrew Waller

Streptococcus equi genomics: Maximising the impact of next generation sequencing data

2020-01 to 2022-01 | Grant
Petplan Charitable Trust (London, GB)
GRANT_NUMBER:

S19-741-780

Source: Self-asserted source
Andrew Waller

First past the post: measuring the fitness of Streptococcus equi strains by SeM allele sequencing

2020-01 to 2021-01 | Grant
Petplan Charitable Trust (London, GB)
GRANT_NUMBER:

S19-824-863

Source: Self-asserted source
Andrew Waller

Utilising the ‘Surveillance of Equine Strangles’ outputs to better understand the dynamics and control of Streptococcus equi transmission

2019-10 to 2023-10 | Grant
The Horse Trust (London, GB)
Source: Self-asserted source
Andrew Waller

Strangles research

2019-02 to 2020-01 | Award
Sir Peter O'Sullevan Charitable Trust (London, GB)
Source: Self-asserted source
Andrew Waller

The identification of equibactin-binding domains and their potential as vaccine targets for the prevention of strangles in horses

2019-01 to 2020-12 | Grant
Petplan Charitable Trust (London, GB)
GRANT_NUMBER:

S18-603-641

Source: Self-asserted source
Andrew Waller

Developing a molecular tool to characterise the phage-Streptococcus equi host infection mechanism to overcome resistance to phage therapy

2019-01 to 2020-01 | Grant
Petplan Charitable Trust (London, GB)
GRANT_NUMBER:

S18-697-735

Source: Self-asserted source
Andrew Waller

Strangles research

2019-01 to 2020-01 | Salary award
The Paul Mellon Foundation (Pennsylvania, US)
Source: Self-asserted source
Andrew Waller

Strangles research

2018-12 to 2019-12 | Award
Alice Noakes Charitable Trust (London, GB)
Source: Self-asserted source
Andrew Waller

Strangles research

2018-11 to 2019-11 | Award
The Ivo Trust (Guildford, GB)
Source: Self-asserted source
Andrew Waller

Strangles research

2018-01 to 2020-12 | Award
Tattersalls (Newmarket, GB)
Source: Self-asserted source
Andrew Waller

Monitoring the menace: development and implementation of a nationwide strangles surveillance system

2018-01 to 2019-12 | Grant
The Horse Trust (London, GB)
GRANT_NUMBER:

G4017

Source: Self-asserted source
Andrew Waller

VACCINE: Velcro vaccines: directing an enhanced immune response

Source: Self-asserted source
Andrew Waller via DimensionsWizard

Improving the safety of future strangles vaccines

2017-01 to 2018-12 | Grant
Petplan Charitable Trust (London, GB)
Source: Self-asserted source
Andrew Waller

Identification of the equibactin receptor: a new vaccine target for the prevention of strangles in horses. Petplan Charitable Trust pump prime award

2017-01 to 2017-12 | Grant
Petplan Charitable Trust (London, GB)
Source: Self-asserted source
Andrew Waller

Breaking the strangles-hold: identification of the mechanisms underlying carriage of Streptococcus equi

2015-10 to 2017-09 | Grant
The Horse Trust (London, GB)
GRANT_NUMBER:

G3015

Source: Self-asserted source
Andrew Waller

Genetic diversity of Streptococcus zooepidemicus isolated from Thoroughbred horses with inflammatory airway disease, and correlation with clinical and cytological findings

2015-05 to 2016-04 | Grant
Horserace Betting Levy Board (London, GB)
GRANT_NUMBER:

SP006

Source: Self-asserted source
Andrew Waller

Identification of new vaccine targets for the prevention of Strangles

2015-05 to 2016-04 | Grant
Horserace Betting Levy Board (London, GB)
GRANT_NUMBER:

vet/prj/774

Source: Self-asserted source
Andrew Waller

Sequencing the donkey genome

2015-01 to 2016-12 | Grant
Donkey Sanctuary (Sidmouth, GB)
Source: Self-asserted source
Andrew Waller

The identification of antigens targeted by the equine immune response for the prevention of strangles

2015-01 to 2015-12 | Grant
Petplan Charitable Trust (London, GB)
GRANT_NUMBER:

S14-51

Source: Self-asserted source
Andrew Waller

Identification of better vaccine targets for the prevention of Strangles

2014-10 to 2018-09 | Grant
Biotechnology and Biological Sciences Research Council (London, GB)
GRANT_NUMBER:

ref:1503883

Source: Self-asserted source
Andrew Waller

Identification of better vaccine targets for the prevention of Strangles

2014-10 to 2018-09 | Grant
Horse Trust (London, GB)
GRANT_NUMBER:

G4104

Source: Self-asserted source
Andrew Waller

Improved diagnosis and epidemiological understanding of Streptococcus zooepidemicus in dogs

2014-01 to 2015-12 | Grant
PetPlan Charitable Trust (London, GB)
GRANT_NUMBER:

S13.26

Source: Self-asserted source
Andrew Waller

Development of a point of care lateral flow device for the rapid identification of horses exposed to Streptococcus equi

2011-05 to 2014-05 | Grant
The Burghley Bursary (London, GB)
Source: Self-asserted source
Andrew Waller

Strangles Research

2011-05 to 2013-05 | Award
European Breeders Fund (London, GB)
Source: Self-asserted source
Andrew Waller

Streptococcus equi evolution: quantification of the importance of key genome acquisition events

2010-10 to 2011-09 | Grant
Horserace Betting Levy Board (London, GB)
GRANT_NUMBER:

vet/prj/758

Source: Self-asserted source
Andrew Waller

Genetic typing of Streptococcus zooepidemicus isolates from dogs with respiratory disease

2010-02 to 2011-02 | Grant
PetPlan Charitable Trust (London, GB)
Source: Self-asserted source
Andrew Waller

Strangles research

2009-11 to 2012-11 | Award
The Anne Duchess of Westminster’s Charitable Trust (London, GB)
Source: Self-asserted source
Andrew Waller

The importance of Streptococcus zooepidemicus surface protein SZO08560 in attachment and/or invasion of the equine respiratory tract

2009-10 to 2012-09 | Grant
Horserace Betting Levy Board (London, GB)
GRANT_NUMBER:

vet/prj/751

Source: Self-asserted source
Andrew Waller

Development of a point-of-care Velox™ diagnostic test for equine strangles

Source: Self-asserted source
Andrew Waller via DimensionsWizard

Strangles research

2009-05 to 2012-05 | Award
Mrs Elise Pilkington's Charitable Trust (London, GB)
Source: Self-asserted source
Andrew Waller

The association between Streptococcus equi infection, reactivation of equine herpesvirus and disease severity in horses

2009-02 to 2010-02 | Grant
PetPlan Charitable Trust (London, GB)
Source: Self-asserted source
Andrew Waller

MLST of S. zooepidemicus

2009-01 to 2009-06 | Contract
Nordvacc (Stockholm, SE)
Source: Self-asserted source
Andrew Waller

Genome sequencing of Sz1775, from a case of equine abortion

2008-11 to 2009-11 | Grant
Royal College of Veterinary Surgeons Charitable Trust (London, GB)
Source: Self-asserted source
Andrew Waller

Genome sequencing of SzBHS5, from a case of acute fatal haemorrhagic pneumonia in dogs

2008-11 to 2009-11 | Grant
Royal College of Veterinary Surgeons Charitable Trust (London, GB)
Source: Self-asserted source
Andrew Waller

The functional and immunological consequences of SeM variation in the pathogenesis of strangles

2007-11 to 2010-10 | Grant
Horserace Betting Levy Board (London, GB)
GRANT_NUMBER:

vet/prj/733

Source: Self-asserted source
Andrew Waller

Determination of SHMAPR live strangles vaccine efficacy in Welsh mountain ponies

2007-07 to 2008-06 | Grant
Horserace Betting Levy Board (London, GB)
GRANT_NUMBER:

vet/prj/734

Source: Self-asserted source
Andrew Waller

Generation of a recombinant type-C Clostridium botulinum toxoid vaccine for the prevention of equine grass sickness

2007-06 to 2008-07 | Grant
Bransby Home of Rest for Horses (Lincoln, GB)
Source: Self-asserted source
Andrew Waller

Breaking the strangles hold

2007-02 to 2009-02 | Award
British Horse Society (London, GB)
Source: Self-asserted source
Andrew Waller

The genetic susceptibility to strangles

2006-11 to 2008-10 | Grant
Bransby Home of Rest for Horses (Lincoln, GB)
Source: Self-asserted source
Andrew Waller

Differentiation of virulent and commensal Streptococcus zooepidemicus from equids

2006-11 to 2007-10 | Grant
Horserace Betting Levy Board (London, GB)
GRANT_NUMBER:

vet/prj/730

Source: Self-asserted source
Andrew Waller

Improved S. equi diagnostics for the more effective management of strangles outbreaks

2006-05 to 2009-05 | Grant
Home of Rest for Horses (London, GB)
GRANT_NUMBER:

G1606

Source: Self-asserted source
Andrew Waller

Evaluation of an improved live attenuated strangles vaccine in horses

2006-01 to 2006-02 | Grant
European Breeders Fund (London, GB)
Source: Self-asserted source
Andrew Waller

Multilocus sequence typing of S. aureus isolates from dogs and their association with antibiotic resistance

2005-09 to 2006-08 | Grant
PetPlan Charitable Trust (London, GB)
GRANT_NUMBER:

05-47

Source: Self-asserted source
Andrew Waller