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https://heleneruffieux.com

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Scopus Author ID: 57196260336

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Employment (1)

University of Cambridge: Cambridge, Cambridgeshire, GB

2019-08-01 to present (MRC Biostatistics Unit,)
Employment
Source: Self-asserted source
Hélène Ruffieux

Works (17)

Efficient Bayesian functional principal component analysis of irregularly-observed multivariate curves

Computational Statistics & Data Analysis
2025-03 | Journal article
DOI: 10.1016/j.csda.2024.108094
Contributors: Tui H. Nolan; Sylvia Richardson; Hélène Ruffieux
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Crossref

A modeling framework for detecting and leveraging node-level information in Bayesian network inference

Biostatistics
2024-12-31 | Journal article
DOI: 10.1093/biostatistics/kxae021
Contributors: Xiaoyue Xi; Hélène Ruffieux
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Crossref

Iron dysregulation and inflammatory stress erythropoiesis associates with long-term outcome of COVID-19

Nature Immunology
2024-03 | Journal article
DOI: 10.1038/s41590-024-01754-8
Contributors: Aimee L. Hanson; Matthew P. Mulè; Hélène Ruffieux; Federica Mescia; Laura Bergamaschi; Victoria S. Pelly; Lorinda Turner; Prasanti Kotagiri; Berthold Göttgens; Christoph Hess et al.
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Crossref

A modelling framework for detecting and leveraging node-level information in Bayesian network inference

2023-09-06 | Preprint
DOI: 10.48550/ARXIV.2309.03067
Contributors: Xiaoyue Xi; Hélène Ruffieux
Source: Self-asserted source
Hélène Ruffieux

A patient-centric modeling framework captures recovery from SARS-CoV-2 infection

Nature Immunology
2023-02 | Journal article
DOI: 10.1038/s41590-022-01380-2
Contributors: Hélène Ruffieux; Aimee L. Hanson; Samantha Lodge; Nathan G. Lawler; Luke Whiley; Nicola Gray; Tui H. Nolan; Laura Bergamaschi; Federica Mescia; Lorinda Turner et al.
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Crossref

Scalable Multiple Network Inference with the Joint Graphical Horseshoe

2022-06-23 | Preprint
DOI: 10.48550/ARXIV.2206.11820
Contributors: Camilla Lingjærde; Benjamin P. Fairfax; Sylvia Richardson; Hélène Ruffieux
Source: Self-asserted source
Hélène Ruffieux

A patient-centric characterization of systemic recovery from SARS-CoV-2 infection

2022-06-19 | Preprint
DOI: 10.1101/2022.06.18.22276437
Contributors: Hélène Ruffieux; Aimee L. Hanson; Samantha Lodge; Nathan G. Lawler; Luke Whiley; Nicola Gray; Tui Nolan; Laura Bergamaschi; Federica Mescia; Nathalie Kingston et al.
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Crossref

Immune checkpoint blockade sensitivity and progression-free survival associates with baseline CD8 + T cell clone size and cytotoxicity

Science Immunology
2021-10-29 | Journal article
DOI: 10.1126/sciimmunol.abj8825
Contributors: Robert A. Watson; Orion Tong; Rosalin Cooper; Chelsea A. Taylor; Piyush K. Sharma; Alba Verge de los Aires; Elise A. Mahé; Hélène Ruffieux; Isar Nassiri; Mark R. Middleton et al.
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Crossref

Longitudinal analysis reveals that delayed bystander CD8+ T cell activation and early immune pathology distinguish severe COVID-19 from mild disease

Immunity
2021-06 | Journal article
DOI: 10.1016/j.immuni.2021.05.010
Contributors: Laura Bergamaschi; Federica Mescia; Lorinda Turner; Aimee L. Hanson; Prasanti Kotagiri; Benjamin J. Dunmore; Hélène Ruffieux; Aloka De Sa; Oisín Huhn; Michael D. Morgan et al.
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Crossref

Delayed bystander CD8 T cell activation, early immune pathology and persistent dysregulation characterise severe COVID-19

2021-01-15 | Other
DOI: 10.1101/2021.01.11.20248765
Contributors: Laura Bergamaschi; Federica Mescia; Lorinda Turner; Aimee Hanson; Prasanti Kotagiri; Benjamin J. Dunmore; Hélène Ruffieux; Aloka De Sa; Oisín Huhn; Michael D Morgan et al.
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Crossref

Sensitivity to Immune Checkpoint Blockade and Progression-Free Survival is associated with baseline CD8+T cell clone size and cytotoxicity

2020-11-16 | Preprint
DOI: 10.1101/2020.11.15.383786
Contributors: RA Watson; O Tong; R Cooper; CA Taylor; PK Sharma; A Verge de Los Aires; EA Mahé; H Ruffieux; I Nassiri; MR Middleton et al.
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Crossref

EPISPOT: an epigenome-driven approach for detecting and interpreting hotspots in molecular QTL studies

2020-09-22 | Preprint
DOI: 10.1101/2020.09.21.305789
Contributors: Hélène Ruffieux; Benjamin P. Fairfax; Isar Nassiri; Elena Vigorito; Chris Wallace; Sylvia Richardson; Leonardo Bottolo
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Crossref

A fully joint Bayesian quantitative trait locus mapping of human protein abundance in plasma

PLOS Computational Biology
2020-06-03 | Journal article
DOI: 10.1371/journal.pcbi.1007882
Contributors: Hélène Ruffieux; Karsten Borgwardt; Jérôme Carayol; Radu Popescu; Mary-Ellen Harper; Robert Dent; Wim H. M. Saris; Arne Astrup; Jörg Hager; Anthony C. Davison et al.
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Crossref

A fully joint Bayesian quantitative trait locus mapping of human protein abundance in plasma

2019-01-18 | Other
DOI: 10.1101/524405
Contributors: Hélène Ruffieux; Jérôme Carayol; Radu Popescu; Mary-Ellen Harper; Robert Dent; Wim H. M. Saris; Arne Astrup; Jörg Hager; Anthony C. Davison; Armand Valsesia
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Crossref

A large-scale multivariate pQTL study sheds light on the genetic architecture of obesity

2019-01-18 | Preprint
Source: Self-asserted source
Hélène Ruffieux

A global-local approach for detecting hotspots in multiple-response regression

2018-11-08 | Preprint
Source: Self-asserted source
Hélène Ruffieux

Efficient inference for genetic association studies with multiple outcomes

Biostatistics
2017 | Journal article
DOI: 10.1093/biostatistics/kxx007
EID:

2-s2.0-85032448364
Contributors: Ruffieux, H.; Davison, A.C.; Hager, J.; Irincheeva, I.
Source: Self-asserted source
Hélène Ruffieux via Scopus - Elsevier

Peer review (2 reviews for 2 publications/grants)

Review activity for American journal of human genetics. (1)
Review activity for PLoS computational biology. (1)
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