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Works (30)

Heterozygous missense variant of the proteasome subunit β-type 9 causes neonatal-onset autoinflammation and immunodeficiency

Nature Communications
2021-12 | Journal article
DOI: 10.1038/s41467-021-27085-y
Part of ISSN: 2041-1723
Contributors: jun hamazaki
Source: Self-asserted source
jun hamazaki

Enhanced O-GlcNAcylation Mediates Cytoprotection under Proteasome Impairment by Promoting Proteasome Turnover in Cancer Cells

IScience
2020 | Journal article
DOI: 10.1016/J.ISCI.2020.101299
WOSUID: WOS:000600609200004
Contributors: Hashimoto, Eiichi; Okuno, Shota; Hirayama, Shoshiro; Arata, Yoshiyuki; Goto, Tsuyoshi; Kosako, Hidetaka; Hamazaki, Jun; Murata, Shigeo
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ER-Resident Transcription Factor Nrf1 Regulates Proteasome Expression and Beyond

International Journal of Molecular Sciences
2020-05 | Journal article | Author
DOI: 10.3390/ijms21103683
Contributors: jun hamazaki; Shigeo Murata
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Multidisciplinary Digital Publishing Institute

NRF3-POMP-20S Proteasome Assembly Axis Promotes Cancer Development via Ubiquitin-Independent Proteolysis of p53 and Retinoblastoma Protein.

Molecular and cellular biology
2020-04 | Journal article
DOI: 10.1128/mcb.00597-19
PMID: 32123008
PMC: PMC7189095
Contributors: Waku T; Nakamura N; Koji M; Watanabe H; Katoh H; Tatsumi C; Tamura N; Hatanaka A; Hirose S; Katayama H et al.
Source: Self-asserted source
jun hamazaki via Europe PubMed Central
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Defective induction of the proteasome associated with T-cell receptor signaling underlies T-cell senescence.

Genes to cells : devoted to molecular & cellular mechanisms
2019-11 | Journal article
DOI: 10.1111/gtc.12728
PMID: 31621149
Contributors: Arata Y; Watanabe A; Motosugi R; Murakami R; Goto T; Hori S; Hirayama S; Hamazaki J; Murata S
Source: Self-asserted source
jun hamazaki via Europe PubMed Central
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Trans-omics Impact of Thymoproteasome in Cortical Thymic Epithelial Cells.

Cell reports
2019-11 | Journal article
DOI: 10.1016/j.celrep.2019.10.079
PMID: 31775054
PMC: PMC6897492
Contributors: Ohigashi I; Tanaka Y; Kondo K; Fujimori S; Kondo H; Palin AC; Hoffmann V; Kozai M; Matsushita Y; Uda S et al.
Source: Self-asserted source
jun hamazaki via Europe PubMed Central
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FAM48A mediates compensatory autophagy induced by proteasome impairment.

Genes to cells : devoted to molecular & cellular mechanisms
2019-07 | Journal article
DOI: 10.1111/gtc.12708
PMID: 31210371
Contributors: Arata Y; Watanabe A; Motosugi R; Iemura SI; Natsume T; Mukai K; Taguchi T; Hirayama S; Hamazaki J; Murata S
Source: Self-asserted source
jun hamazaki via Europe PubMed Central
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Shigella effector IpaH4.5 targets 19S regulatory particle subunit RPN13 in the 26S proteasome to dampen cytotoxic T lymphocyte activation.

Cellular microbiology
2018-12 | Journal article
DOI: 10.1111/cmi.12974
PMID: 30414351
Contributors: Otsubo R; Mimuro H; Ashida H; Hamazaki J; Murata S; Sasakawa C
Source: Self-asserted source
jun hamazaki via Europe PubMed Central
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Specific Modification of Aged Proteasomes Revealed by Tag-Exchangeable Knock-In Mice.

Molecular and cellular biology
2018-12 | Journal article
DOI: 10.1128/mcb.00426-18
PMID: 30348842
PMC: PMC6290375
Contributors: Tomita T; Hirayama S; Sakurai Y; Ohte Y; Yoshihara H; Saeki Y; Hamazaki J; Murata S
Source: Self-asserted source
jun hamazaki via Europe PubMed Central
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PAC1-PAC2 proteasome assembly chaperone retains the core α4-α7 assembly intermediates in the cytoplasm.

Genes to cells : devoted to molecular & cellular mechanisms
2018-08 | Journal article
DOI: 10.1111/gtc.12631
PMID: 30133132
Contributors: Wu W; Sahara K; Hirayama S; Zhao X; Watanabe A; Hamazaki J; Yashiroda H; Murata S
Source: Self-asserted source
jun hamazaki via Europe PubMed Central
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Transcriptional regulation of the 26S proteasome by Nrf1.

Proceedings of the Japan Academy. Series B, Physical and Biological Sciences
2018-01 | Journal article
DOI: 10.2183/pjab.94.021
PMID: 30305478
PMC: PMC6275327
Contributors: Koizumi S; Hamazaki J; Murata S
Source: Self-asserted source
jun hamazaki via Europe PubMed Central
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Ubiquitin-Binding Protein CG5445 Suppresses Aggregation and Cytotoxicity of Amyotrophic Lateral Sclerosis-Linked TDP-43 in Drosophila.

Molecular and cellular biology
2018-01 | Journal article
DOI: 10.1128/mcb.00195-17
PMID: 29109084
PMC: PMC5770533
Contributors: Uechi H; Kuranaga E; Iriki T; Takano K; Hirayama S; Miura M; Hamazaki J; Murata S
Source: Self-asserted source
jun hamazaki via Europe PubMed Central
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Early and consistent overexpression of ADRM1 in ovarian high-grade serous carcinoma.

Journal of ovarian research
2017-08 | Journal article
DOI: 10.1186/s13048-017-0347-y
PMID: 28784174
PMC: PMC5547474
Contributors: Jiang RT; Yemelyanova A; Xing D; Anchoori RK; Hamazaki J; Murata S; Seidman JD; Wang TL; Roden RBS
Source: Self-asserted source
jun hamazaki via Europe PubMed Central
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Structure of the Rpn13-Rpn2 complex provides insights for Rpn13 and Uch37 as anticancer targets.

Nature communications
2017-06 | Journal article
DOI: 10.1038/ncomms15540
PMID: 28598414
PMC: PMC5494190
Contributors: Lu X; Nowicka U; Sridharan V; Liu F; Randles L; Hymel D; Dyba M; Tarasov SG; Tarasova NI; Zhao XZ et al.
Source: Self-asserted source
jun hamazaki via Europe PubMed Central
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Foxn1-β5t transcriptional axis controls CD8+ T-cell production in the thymus.

Nature communications
2017-02 | Journal article
DOI: 10.1038/ncomms14419
PMID: 28176764
PMC: PMC5309848
Contributors: Uddin MM; Ohigashi I; Motosugi R; Nakayama T; Sakata M; Hamazaki J; Nishito Y; Rode I; Tanaka K; Takemoto T et al.
Source: Self-asserted source
jun hamazaki via Europe PubMed Central
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The aspartyl protease DDI2 activates Nrf1 to compensate for proteasome dysfunction.

eLife
2016-08 | Journal article
DOI: 10.7554/elife.18357
PMID: 27528193
PMC: PMC5001836
Contributors: Koizumi S; Irie T; Hirayama S; Sakurai Y; Yashiroda H; Naguro I; Ichijo H; Hamazaki J; Murata S
Source: Self-asserted source
jun hamazaki via Europe PubMed Central
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Redundant Roles of Rpn10 and Rpn13 in Recognition of Ubiquitinated Proteins and Cellular Homeostasis.

PLoS genetics
2015-07 | Journal article
DOI: 10.1371/journal.pgen.1005401
PMID: 26222436
PMC: PMC4519129
Contributors: Hamazaki J; Hirayama S; Murata S
Source: Self-asserted source
jun hamazaki via Europe PubMed Central
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Sirt1-deficiency causes defective protein quality control.

Scientific reports
2015-07 | Journal article
DOI: 10.1038/srep12613
PMID: 26219988
PMC: PMC4518232
Contributors: Tomita T; Hamazaki J; Hirayama S; McBurney MW; Yashiroda H; Murata S
Source: Self-asserted source
jun hamazaki via Europe PubMed Central
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Characterization of the testis-specific proteasome subunit α4s in mammals.

The Journal of biological chemistry
2014-03 | Journal article
DOI: 10.1074/jbc.m114.558866
PMID: 24668818
PMC: PMC4007433
Contributors: Uechi H; Hamazaki J; Murata S
Source: Self-asserted source
jun hamazaki via Europe PubMed Central
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Mouse zygote-specific proteasome assembly chaperone important for maternal-to-zygotic transition.

Biology open
2012-11 | Journal article
DOI: 10.1242/bio.20123020
PMID: 23429752
PMC: PMC3575651
Contributors: Shin SW; Shimizu N; Tokoro M; Nishikawa S; Hatanaka Y; Anzai M; Hamazaki J; Kishigami S; Saeki K; Hosoi Y et al.
Source: Self-asserted source
jun hamazaki via Europe PubMed Central
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A mutation in the immunoproteasome subunit PSMB8 causes autoinflammation and lipodystrophy in humans.

The Journal of clinical investigation
2011-09 | Journal article
DOI: 10.1172/jci58414
PMID: 21881205
PMC: PMC3195477
Contributors: Kitamura A; Maekawa Y; Uehara H; Izumi K; Kawachi I; Nishizawa M; Toyoshima Y; Takahashi H; Standley DM; Tanaka K et al.
Source: Self-asserted source
jun hamazaki via Europe PubMed Central
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PAC1 gene knockout reveals an essential role of chaperone-mediated 20S proteasome biogenesis and latent 20S proteasomes in cellular homeostasis.

Molecular and cellular biology
2010-05 | Journal article
DOI: 10.1128/mcb.00216-10
PMID: 20498273
PMC: PMC2916404
Contributors: Sasaki K; Hamazaki J; Koike M; Hirano Y; Komatsu M; Uchiyama Y; Tanaka K; Murata S
Source: Self-asserted source
jun hamazaki via Europe PubMed Central
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Crystal structure of the de-ubiquitinating enzyme UCH37 (human UCH-L5) catalytic domain.

Biochemical and biophysical research communications
2009-10 | Journal article
DOI: 10.1016/j.bbrc.2009.10.062
PMID: 19836345
Contributors: Nishio K; Kim SW; Kawai K; Mizushima T; Yamane T; Hamazaki J; Murata S; Tanaka K; Morimoto Y
Source: Self-asserted source
jun hamazaki via Europe PubMed Central
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Assembly pathway of the Mammalian proteasome base subcomplex is mediated by multiple specific chaperones.

Cell
2009-05 | Journal article
DOI: 10.1016/j.cell.2009.05.008
PMID: 19490896
Contributors: Kaneko T; Hamazaki J; Iemura S; Sasaki K; Furuyama K; Natsume T; Tanaka K; Murata S
Source: Self-asserted source
jun hamazaki via Europe PubMed Central
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17-DMAG ameliorates polyglutamine-mediated motor neuron degeneration through well-preserved proteasome function in an SBMA model mouse.

Human molecular genetics
2008-12 | Journal article
DOI: 10.1093/hmg/ddn419
PMID: 19066230
Contributors: Tokui K; Adachi H; Waza M; Katsuno M; Minamiyama M; Doi H; Tanaka K; Hamazaki J; Murata S; Tanaka F et al.
Source: Self-asserted source
jun hamazaki via Europe PubMed Central
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Genetic evidence linking age-dependent attenuation of the 26S proteasome with the aging process.

Molecular and cellular biology
2008-12 | Journal article
DOI: 10.1128/mcb.01227-08
PMID: 19075009
PMC: PMC2643801
Contributors: Tonoki A; Kuranaga E; Tomioka T; Hamazaki J; Murata S; Tanaka K; Miura M
Source: Self-asserted source
jun hamazaki via Europe PubMed Central
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Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice.

Cell
2007-12 | Journal article
DOI: 10.1016/j.cell.2007.10.035
PMID: 18083104
Contributors: Komatsu M; Waguri S; Koike M; Sou YS; Ueno T; Hara T; Mizushima N; Iwata J; Ezaki J; Murata S et al.
Source: Self-asserted source
jun hamazaki via Europe PubMed Central
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Rpn10-mediated degradation of ubiquitinated proteins is essential for mouse development.

Molecular and cellular biology
2007-07 | Journal article
DOI: 10.1128/mcb.00509-07
PMID: 17646385
PMC: PMC2099239
Contributors: Hamazaki J; Sasaki K; Kawahara H; Hisanaga S; Tanaka K; Murata S
Source: Self-asserted source
jun hamazaki via Europe PubMed Central
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A novel proteasome interacting protein recruits the deubiquitinating enzyme UCH37 to 26S proteasomes.

The EMBO journal
2006-09 | Journal article
DOI: 10.1038/sj.emboj.7601338
PMID: 16990800
PMC: PMC1589993
Contributors: Hamazaki J; Iemura S; Natsume T; Yashiroda H; Tanaka K; Murata S
Source: Self-asserted source
jun hamazaki via Europe PubMed Central
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Genetic analysis of Rpn10 subunit in mice

Cell Structure and Function
2005 | Journal article
WOSUID: WOS:000202995600311
Contributors: Hamazaki, Jun; Tanaka, Keiji; Murata, Shigeo
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Peer review (41 reviews for 12 publications/grants)

Review activity for Biomolecules. (1)
Review activity for Cancers. (2)
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Review activity for Communications biology. (2)
Review activity for International journal of molecular sciences. (21)
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