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Employment (3)

Københavns Universitet: København K, DK

Employment
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University of Copenhagen

University of Copenhagen Biotech Research and Innovation Centre: Copenhagen, DK

2016-03-01 to present | Postdoctoral Researcher (Finsen laboratory)
Employment
Source: Self-asserted source
Montserrat Estruch

Instituto de Investigacion Hospital Sant Pau Barcelona: Barcelona, Catalunya, ES

2012-02 to 2016-02 | Researcher in clinical trials (Biochemistry)
Employment
Source: Self-asserted source
Montserrat Estruch

Education and qualifications (3)

Universitat Autònoma de Barcelona: Bellaterra, Catalunya, ES

2011-09 to 2014-09 | Doctor (Biochemistry)
Education
Source: Self-asserted source
Montserrat Estruch

Universitat Autònoma de Barcelona: Bellaterra, Catalunya, ES

2010-09 to 2011-09 | Master in Science (Biochemistry)
Education
Source: Self-asserted source
Montserrat Estruch

Universitat Autònoma de Barcelona: Bellaterra, Catalunya, ES

2006-09-01 to 2010-07-01 | Bachelor in Sciences (Health Biology)
Education
Source: Self-asserted source
Montserrat Estruch

Works (40)

Endomucin marks quiescent long-term multi-lineage repopulating hematopoietic stem cells and is essential for their transendothelial migration

Cell Reports
2024 | Journal article | Author
DOI: 10.1016/j.celrep.2024.114475
SOURCE-WORK-ID:

1e46d238-822c-4ad2-ad79-56bc30f0e71e

EID:

2-s2.0-85198069529

PMID: 38996072
Contributors: Sophia Engelhard; Montserrat Estruch; Shuyu Qin; Christoph A. Engelhard; Francisco G Rodriguez Gonzalez; Martine Drilsvik; Javier Martin-Gonzalez; Jeng Wei Lu; David Bryder; Claus Nerlov et al.
Source: check_circle
University of Copenhagen

Presence of Ceramidase Activity in Electronegative LDL

International Journal of Molecular Sciences
2023 | Journal article | Author
DOI: 10.3390/ijms24010165
SOURCE-WORK-ID:

7584a3a2-b0c7-484e-8865-27707057e0a4

EID:

2-s2.0-85145979312

PMID: 36613609
Contributors: Núria Puig; Jose Rives; Montserrat Estruch; Ana Aguilera-Simon; Noemi Rotllan; Mercedes Camacho; Núria Colomé; Francesc Canals; José Luis Sánchez-Quesada; Sonia Benitez
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University of Copenhagen

Data from Inhibition of Oxidized Nucleotide Sanitation By TH1579 and Conventional Chemotherapy Cooperatively Enhance Oxidative DNA Damage and Survival in AML

2023-04-03 | Preprint
DOI: 10.1158/1535-7163.c.6543309.v1
Contributors: Anders Centio; Montserrat Estruch; Kristian Reckzeh; Kumar Sanjiv; Camilla Vittori; Sophia Engelhard; Ulrika Warpman Berglund; Thomas Helleday; Kim Theilgaard-Mönch
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Crossref

Data from Inhibition of Oxidized Nucleotide Sanitation By TH1579 and Conventional Chemotherapy Cooperatively Enhance Oxidative DNA Damage and Survival in AML

2023-04-03 | Preprint
DOI: 10.1158/1535-7163.c.6543309
Contributors: Anders Centio; Montserrat Estruch; Kristian Reckzeh; Kumar Sanjiv; Camilla Vittori; Sophia Engelhard; Ulrika Warpman Berglund; Thomas Helleday; Kim Theilgaard-Mönch
Source: check_circle
Crossref

Supplementary Figure from Inhibition of Oxidized Nucleotide Sanitation By TH1579 and Conventional Chemotherapy Cooperatively Enhance Oxidative DNA Damage and Survival in AML

2023-04-03 | Preprint
DOI: 10.1158/1535-7163.22522227.v1
Contributors: Anders Centio; Montserrat Estruch; Kristian Reckzeh; Kumar Sanjiv; Camilla Vittori; Sophia Engelhard; Ulrika Warpman Berglund; Thomas Helleday; Kim Theilgaard-Mönch
Source: check_circle
Crossref

Supplementary Figure from Inhibition of Oxidized Nucleotide Sanitation By TH1579 and Conventional Chemotherapy Cooperatively Enhance Oxidative DNA Damage and Survival in AML

2023-04-03 | Preprint
DOI: 10.1158/1535-7163.22522224
Contributors: Anders Centio; Montserrat Estruch; Kristian Reckzeh; Kumar Sanjiv; Camilla Vittori; Sophia Engelhard; Ulrika Warpman Berglund; Thomas Helleday; Kim Theilgaard-Mönch
Source: check_circle
Crossref

Supplementary Figure from Inhibition of Oxidized Nucleotide Sanitation By TH1579 and Conventional Chemotherapy Cooperatively Enhance Oxidative DNA Damage and Survival in AML

2023-04-03 | Preprint
DOI: 10.1158/1535-7163.22522218
Contributors: Anders Centio; Montserrat Estruch; Kristian Reckzeh; Kumar Sanjiv; Camilla Vittori; Sophia Engelhard; Ulrika Warpman Berglund; Thomas Helleday; Kim Theilgaard-Mönch
Source: check_circle
Crossref

Supplementary Figure from Inhibition of Oxidized Nucleotide Sanitation By TH1579 and Conventional Chemotherapy Cooperatively Enhance Oxidative DNA Damage and Survival in AML

2023-04-03 | Preprint
DOI: 10.1158/1535-7163.22522215
Contributors: Anders Centio; Montserrat Estruch; Kristian Reckzeh; Kumar Sanjiv; Camilla Vittori; Sophia Engelhard; Ulrika Warpman Berglund; Thomas Helleday; Kim Theilgaard-Mönch
Source: check_circle
Crossref

Supplementary Figure from Inhibition of Oxidized Nucleotide Sanitation By TH1579 and Conventional Chemotherapy Cooperatively Enhance Oxidative DNA Damage and Survival in AML

2023-04-03 | Preprint
DOI: 10.1158/1535-7163.22522212.v1
Contributors: Anders Centio; Montserrat Estruch; Kristian Reckzeh; Kumar Sanjiv; Camilla Vittori; Sophia Engelhard; Ulrika Warpman Berglund; Thomas Helleday; Kim Theilgaard-Mönch
Source: check_circle
Crossref

Supplementary Figure from Inhibition of Oxidized Nucleotide Sanitation By TH1579 and Conventional Chemotherapy Cooperatively Enhance Oxidative DNA Damage and Survival in AML

2023-04-03 | Preprint
DOI: 10.1158/1535-7163.22522221
Contributors: Anders Centio; Montserrat Estruch; Kristian Reckzeh; Kumar Sanjiv; Camilla Vittori; Sophia Engelhard; Ulrika Warpman Berglund; Thomas Helleday; Kim Theilgaard-Mönch
Source: check_circle
Crossref

Supplementary Figure from Inhibition of Oxidized Nucleotide Sanitation By TH1579 and Conventional Chemotherapy Cooperatively Enhance Oxidative DNA Damage and Survival in AML

2023-04-03 | Preprint
DOI: 10.1158/1535-7163.22522206.v1
Contributors: Anders Centio; Montserrat Estruch; Kristian Reckzeh; Kumar Sanjiv; Camilla Vittori; Sophia Engelhard; Ulrika Warpman Berglund; Thomas Helleday; Kim Theilgaard-Mönch
Source: check_circle
Crossref

Supplementary Figure from Inhibition of Oxidized Nucleotide Sanitation By TH1579 and Conventional Chemotherapy Cooperatively Enhance Oxidative DNA Damage and Survival in AML

2023-04-03 | Preprint
DOI: 10.1158/1535-7163.22522215.v1
Contributors: Anders Centio; Montserrat Estruch; Kristian Reckzeh; Kumar Sanjiv; Camilla Vittori; Sophia Engelhard; Ulrika Warpman Berglund; Thomas Helleday; Kim Theilgaard-Mönch
Source: check_circle
Crossref

Supplementary Figure from Inhibition of Oxidized Nucleotide Sanitation By TH1579 and Conventional Chemotherapy Cooperatively Enhance Oxidative DNA Damage and Survival in AML

2023-04-03 | Preprint
DOI: 10.1158/1535-7163.22522212
Contributors: Anders Centio; Montserrat Estruch; Kristian Reckzeh; Kumar Sanjiv; Camilla Vittori; Sophia Engelhard; Ulrika Warpman Berglund; Thomas Helleday; Kim Theilgaard-Mönch
Source: check_circle
Crossref

Supplementary Figure from Inhibition of Oxidized Nucleotide Sanitation By TH1579 and Conventional Chemotherapy Cooperatively Enhance Oxidative DNA Damage and Survival in AML

2023-04-03 | Preprint
DOI: 10.1158/1535-7163.22522218.v1
Contributors: Anders Centio; Montserrat Estruch; Kristian Reckzeh; Kumar Sanjiv; Camilla Vittori; Sophia Engelhard; Ulrika Warpman Berglund; Thomas Helleday; Kim Theilgaard-Mönch
Source: check_circle
Crossref

Supplementary Figure from Inhibition of Oxidized Nucleotide Sanitation By TH1579 and Conventional Chemotherapy Cooperatively Enhance Oxidative DNA Damage and Survival in AML

2023-04-03 | Preprint
DOI: 10.1158/1535-7163.22522227
Contributors: Anders Centio; Montserrat Estruch; Kristian Reckzeh; Kumar Sanjiv; Camilla Vittori; Sophia Engelhard; Ulrika Warpman Berglund; Thomas Helleday; Kim Theilgaard-Mönch
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Crossref

Supplementary Figure from Inhibition of Oxidized Nucleotide Sanitation By TH1579 and Conventional Chemotherapy Cooperatively Enhance Oxidative DNA Damage and Survival in AML

2023-04-03 | Preprint
DOI: 10.1158/1535-7163.22522209
Contributors: Anders Centio; Montserrat Estruch; Kristian Reckzeh; Kumar Sanjiv; Camilla Vittori; Sophia Engelhard; Ulrika Warpman Berglund; Thomas Helleday; Kim Theilgaard-Mönch
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Crossref

Supplementary Figure from Inhibition of Oxidized Nucleotide Sanitation By TH1579 and Conventional Chemotherapy Cooperatively Enhance Oxidative DNA Damage and Survival in AML

2023-04-03 | Preprint
DOI: 10.1158/1535-7163.22522224.v1
Contributors: Anders Centio; Montserrat Estruch; Kristian Reckzeh; Kumar Sanjiv; Camilla Vittori; Sophia Engelhard; Ulrika Warpman Berglund; Thomas Helleday; Kim Theilgaard-Mönch
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Crossref

Supplementary Figure from Inhibition of Oxidized Nucleotide Sanitation By TH1579 and Conventional Chemotherapy Cooperatively Enhance Oxidative DNA Damage and Survival in AML

2023-04-03 | Preprint
DOI: 10.1158/1535-7163.22522221.v1
Contributors: Anders Centio; Montserrat Estruch; Kristian Reckzeh; Kumar Sanjiv; Camilla Vittori; Sophia Engelhard; Ulrika Warpman Berglund; Thomas Helleday; Kim Theilgaard-Mönch
Source: check_circle
Crossref

Supplementary Figure from Inhibition of Oxidized Nucleotide Sanitation By TH1579 and Conventional Chemotherapy Cooperatively Enhance Oxidative DNA Damage and Survival in AML

2023-04-03 | Preprint
DOI: 10.1158/1535-7163.22522206
Contributors: Anders Centio; Montserrat Estruch; Kristian Reckzeh; Kumar Sanjiv; Camilla Vittori; Sophia Engelhard; Ulrika Warpman Berglund; Thomas Helleday; Kim Theilgaard-Mönch
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Crossref

Supplementary Figure from Inhibition of Oxidized Nucleotide Sanitation By TH1579 and Conventional Chemotherapy Cooperatively Enhance Oxidative DNA Damage and Survival in AML

2023-04-03 | Preprint
DOI: 10.1158/1535-7163.22522209.v1
Contributors: Anders Centio; Montserrat Estruch; Kristian Reckzeh; Kumar Sanjiv; Camilla Vittori; Sophia Engelhard; Ulrika Warpman Berglund; Thomas Helleday; Kim Theilgaard-Mönch
Source: check_circle
Crossref

TET2 deficiency cooperates with CBFB-MYH11 to induce acute myeloid leukaemia and represents an early leukaemogenic event

British Journal of Haematology
2022 | Journal article | Author
DOI: 10.1111/bjh.18027
SOURCE-WORK-ID:

c6ea39a4-44d7-4ac3-92f3-90f927343879

WOSUID:

000751658200001

PMID: 35128634
EID:

2-s2.0-85124476051
Contributors: Kristian Reckzeh; Montserrat Estruch; Mina Ali; Alexandra Søgaard Helbo; Anna Mosbech; Kyoung Jae Won; Frank Rücker; Konstanze Döhner; Kim Theilgaard-Mönch
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University of Copenhagen

Inhibition of Oxidized Nucleotide Sanitation By TH1579 and Conventional Chemotherapy Cooperatively Enhance Oxidative DNA Damage and Survival in AML

Molecular Cancer Therapeutics
2022-05-04 | Journal article
DOI: 10.1158/1535-7163.MCT-21-0185
Contributors: Anders Centio; Montserrat Estruch; Kristian Reckzeh; Kumar Sanjiv; Camilla Vittori; Sophia Engelhard; Ulrika Warpman Berglund; Thomas Helleday; Kim Theilgaard-Mönch
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Crossref
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MTH1 Inhibitor TH1579 Induces Oxidative DNA Damage and Mitotic Arrest in Acute Myeloid Leukemia

Cancer Research
2021 | Journal article | Author
DOI: 10.1158/0008-5472.CAN-21-0061
SOURCE-WORK-ID:

2cd6dc8a-8f39-4583-9cb3-26633b130d5d

PMID: 34593524
WOSUID:

000719879600016

EID:

2-s2.0-85119472509
Contributors: Kumar Sanjiv; José Manuel Calderón-Montaño; Therese M Pham; Tom Erkers; Viktoriia Tsuber; Ingrid Almlöf; Andreas Höglund; Yaser Heshmati; Brinton Seashore-Ludlow; Akhilesh Nagesh Danda et al.
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University of Copenhagen

Novel Combination Treatments for AML

Journal of Cellular Immunology
2021 | Journal article | Author
DOI: 10.33696/immunology.3.105
SOURCE-WORK-ID:

1007dfb3-5977-45ed-9266-dccbf28c28b6
Contributors: Montserrat Estruch; Camilla Vittori; Teresa Muñoz-Montesinos; Kristian Reckzeh; Kim Theilgaard-Mönch
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University of Copenhagen

Targeting of PI3K/AKT signaling and DNA damage response in acute myeloid leukemia

Cancer Drug Resistance
2021 | Journal article | Author
DOI: 10.20517/cdr.2021.76
SOURCE-WORK-ID:

2dfcb035-5dce-4585-b7e2-ee33b0924584

EID:

2-s2.0-85123370145

PMID: 35582388
WOSUID:

000849619900019
Contributors: Montserrat Estruch; Camilla Vittori; Teresa Muñoz Montesinos; Kristian Reckzeh; Kim Theilgaard-Mönch
Source: check_circle
University of Copenhagen

Targeted inhibition of cooperative mutation- and therapy-induced AKT activation in AML effectively enhances response to chemotherapy

Leukemia
2021-07-09 | Journal article
DOI: 10.1038/s41375-020-01094-0
Contributors: Montserrat Estruch; Kristian Reckzeh; Camilla Vittori; Anders Centio; Mina Ali; Sophia Engelhard; Ling Zhao; Kyoung Jae Won; Paul Liu; Bo Torben Porse et al.
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Crossref
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Preferred source (of 2)‎

Inhibition of oxidised nucleotide sanitation effectively enhances chemotherapy response in AML

2019-10-03 | Conference poster
Source: Self-asserted source
Montserrat Estruch

The Role of Distinctive Sphingolipids in the Inflammatory and Apoptotic Effects of Electronegative LDL on Monocytes.

Biomolecules
2019-07 | Journal article
DOI: 10.3390/biom9080300
PMID: 31344975
PMC: PMC6722802
Contributors: Puig N; Estruch M; Jin L; Sanchez-Quesada JL; Benitez S
Source: Self-asserted source
Montserrat Estruch via Europe PubMed Central

PI3K inhibition combined with standard chemotherapy effectively inhibits KIT mutant AML

Annual Conference of the European Hematology Association (EHA)
2019-06-13 | Conference abstract
Source: Self-asserted source
Montserrat Estruch

Human adult HSCs can be discriminated from lineage-committed HPCs by the expression of endomucin

Blood Advances
2018-07-10 | Journal article
DOI: 10.1182/bloodadvances.2018015743
Contributors: Kristian Reckzeh; Hüsün Kizilkaya; Alexandra Søgaard Helbo; Montserrat Estruch Alrich; André Gundersen Deslauriers; Amit Grover; Nicolas Rapin; Fazila Asmar; Kirsten Grønbæk; Bo Porse et al.
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Crossref
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TARGETED COMBINATION THERAPY AGAINST ONCOGENIC PI3K/AKT/MTOR AND NFKB SIGNALLING PATHWAYS USING ACUTE MYELOID LEUKEMIA AS A CANCER MODEL

EHA Learning Center
2018-06-16 | Conference paper
SOURCE-WORK-ID:

215289
Source: Self-asserted source
Montserrat Estruch

Targeted Combination Therapy against Oncogenic PI3K/AKT/MTOR and NFKB Signalling Pathways In Cancer Patients

Marie Curie Seminars
2018-05-24 | Conference paper
SOURCE-WORK-ID:

O10
Source: Self-asserted source
Montserrat Estruch

Increased inflammatory effect of electronegative LDL and decreased protection by HDL in type 2 diabetic patients.

Atherosclerosis
2017-07 | Journal article
DOI: 10.1016/j.atherosclerosis.2017.07.015
PMID: 28734591
Contributors: Estruch M; Miñambres I; Sanchez-Quesada JL; Soler M; Pérez A; Ordoñez-Llanos J; Benitez S
Source: Self-asserted source
Montserrat Estruch via Europe PubMed Central

Inflammatory intracellular pathways activated by electronegative LDL in monocytes.

Biochimica et biophysica acta
2016-05 | Journal article
DOI: 10.1016/j.bbalip.2016.05.010
PMID: 27235719
Contributors: Estruch M; Sanchez-Quesada JL; Ordoñez-Llanos J; Benitez S
Source: Self-asserted source
Montserrat Estruch via Europe PubMed Central

Electronegative LDL induces priming and inflammasome activation leading to IL-1β release in human monocytes and macrophages.

Biochimica et biophysica acta
2015-08 | Journal article
DOI: 10.1016/j.bbalip.2015.08.009
PMID: 26327597
Contributors: Estruch M; Rajamäki K; Sanchez-Quesada JL; Kovanen PT; Öörni K; Benitez S; Ordoñez-Llanos J
Source: Self-asserted source
Montserrat Estruch via Europe PubMed Central

Ceramide-enriched LDL induces cytokine release through TLR4 and CD14 in monocytes. Similarities with electronegative LDL.

Clinica e investigacion en arteriosclerosis : publicacion oficial de la Sociedad Espanola de Arteriosclerosis
2014-03 | Journal article
DOI: 10.1016/j.arteri.2013.12.003
PMID: 24630524
Contributors: Estruch M; Sánchez-Quesada JL; Ordóñez-Llanos J; Benítez S
Source: Self-asserted source
Montserrat Estruch via Europe PubMed Central

Electronegative LDL: a circulating modified LDL with a role in inflammation.

Mediators of Inflammation
2013-08 | Journal article
DOI: 10.1155/2013/181324
PMID: 24062611
PMC: PMC3766570
Contributors: Estruch M; Sánchez-Quesada JL; Ordóñez Llanos J; Benítez S
Source: Self-asserted source
Montserrat Estruch via Europe PubMed Central

Eplerenone in systemic right ventricle: double blind randomized clinical trial. The evedes study.

International journal of cardiology
2013-07 | Journal article
DOI: 10.1016/j.ijcard.2013.07.163
PMID: 23972966
Contributors: Dos L; Pujadas S; Estruch M; Mas A; Ferreira-González I; Pijuan A; Serra R; Ordóñez-Llanos J; Subirana M; Pons-Lladó G et al.
Source: Self-asserted source
Montserrat Estruch via Europe PubMed Central

CD14 and TLR4 mediate cytokine release promoted by electronegative LDL in monocytes.

Atherosclerosis
2013-05 | Journal article
DOI: 10.1016/j.atherosclerosis.2013.05.011
PMID: 23880187
Contributors: Estruch M; Bancells C; Beloki L; Sanchez-Quesada JL; Ordóñez-Llanos J; Benitez S
Source: Self-asserted source
Montserrat Estruch via Europe PubMed Central

The Induction of Cytokine Release in Monocytes by Electronegative Low-Density Lipoprotein (LDL) Is Related to Its Higher Ceramide Content than Native LDL.

International journal of molecular sciences
2013-01 | Journal article
DOI: 10.3390/ijms14022601
PMID: 23358250
PMC: PMC3588005
Contributors: Estruch M; Sanchez-Quesada JL; Beloki L; Ordoñez-Llanos J; Benitez S
Source: Self-asserted source
Montserrat Estruch via Europe PubMed Central
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