Personal information

Websites & social links

http://www.mh-hannover.de/routier_francoise.html

Other IDs

Scopus Author ID: 57204280777
SciProfiles: 184480

Keywords

Glycobiology, Fungi, Protozoan parasites, Aspergillus fumigatus, Leishmania

Countries

Germany

Activities

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Employment (1)

Hannover Medical School: Hanover, Niedersachsen, DE

2001-07-01 to present | Professor (Clinical Biochemistry)
Employment
Source: Self-asserted source
Francoise Routier

Works (50 of 54)

Items per page:
Page 1 of 2

Identification of Compounds Preventing <i>A. fumigatus</i> Biofilm Formation by Inhibition of the Galactosaminogalactan Deacetylase Agd3

International Journal of Molecular Sciences
2023-01 | Journal article | Author
DOI: 10.3390/ijms24031851
Contributors: Carla I. I. Seegers; Danielle Lee; Patricia Zarnovican; Susanne H. Kirsch; Rolf Müller; Thomas Haselhorst; Francoise Routier
Source: check_circle
Multidisciplinary Digital Publishing Institute

Characterization of a gene cluster involved in Aspergillus fumigatus zwitterionic glycosphingolipid synthesis

Glycobiology
2022 | Journal article
DOI: 10.1093/glycob/cwac036
EID:

2-s2.0-85136910295

Part of ISSN: 14602423
Contributors: Seegers, C.I.I.; Ramón Roth, I.; Zarnovican, P.; Buettner, F.F.R.; Routier, F.H.
Source: Self-asserted source
Francoise Routier via Scopus - Elsevier

C-Mannosylation of Toxoplasma gondii proteins promotes attachment to host cells and parasite virulence

Journal of Biological Chemistry
2020 | Journal article
DOI: 10.1074/jbc.RA119.010590
EID:

2-s2.0-85078560175

Part of ISSN: 1083351X 00219258
Contributors: Albuquerque-Wendt, A.; Jacot, D.; Dos Santos Pacheco, N.; Seegers, C.; Zarnovican, P.; Buettner, F.F.R.; Bakker, H.; Soldati-Favre, D.; Routier, F.H.
Source: Self-asserted source
Francoise Routier via Scopus - Elsevier

Proteoglycan-Dependent Endo-Lysosomal Fusion Affects Intracellular Survival of Salmonella Typhimurium in Epithelial Cells

Frontiers in Immunology
2020 | Journal article
DOI: 10.3389/fimmu.2020.00731
EID:

2-s2.0-85084669993

Part of ISSN: 16643224
Contributors: Galeev, A.; Suwandi, A.; Bakker, H.; Oktiviyari, A.; Routier, F.H.; Krone, L.; Hensel, M.; Grassl, G.A.
Source: Self-asserted source
Francoise Routier via Scopus - Elsevier

Glycobiology of Human Fungal Pathogens: New Avenues for Drug Development

Cells
2019-10 | Journal article | Author
DOI: 10.3390/cells8111348
Contributors: Danielle Lee; Holly O'Donnell; Francoise Routier; Joe Tiralongo; Thomas Haselhorst
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

Membrane Topological Model of Glycosyltransferases of the GT-C Superfamily

International Journal of Molecular Sciences
2019-09 | Journal article | Author
DOI: 10.3390/ijms20194842
Contributors: Andreia Albuquerque or Albuquerque-Wendt; Hermann J. Hütte; Falk F. R. Buettner; Francoise Routier; Hans Bakker
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

Identification of <i>Leishmania major</i> UDP-Sugar Pyrophosphorylase Inhibitors Using Biosensor-Based Small Molecule Fragment Library Screening

Molecules
2019-03 | Journal article | Author
DOI: 10.3390/molecules24050996
Contributors: Ohm Prakash; Jana Führing; John Post; Sharon M. Shepherd; Thomas C. Eadsforth; David Gray; Roman Fedorov; Francoise Routier
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

Protein O- and C-Glycosylation pathways in Toxoplasma gondii and Plasmodium falciparum.

Parasitology
2019-02-18 | Journal article
DOI: 10.1017/s0031182019000040
PMID: 30773146
Source: Self-asserted source
Francoise Routier
grade
Preferred source (of 2)‎

O-fucosylation of thrombospondin-like repeats is required for processing of MIC2 and for efficient host cell invasion by Toxoplasma gondii tachyzoites

bioRxiv
2018 | Other
DOI: 10.1101/382515
EID:

2-s2.0-85095628285

Part of ISSN: 26928205
Contributors: Bandini, G.; Leon, D.R.; Hoppe, C.M.; Zhang, Y.; Agop-Nersesian, C.; Shears, M.J.; Mahal, L.K.; Routier, F.H.; Costello, C.E.; Samuelson, J.
Source: Self-asserted source
Francoise Routier via Scopus - Elsevier

O-Fucosylation of thrombospondin-like repeats is required for processing of microneme protein 2 and for efficient host cell invasion by Toxoplasma gondii tachyzoites.

The Journal of biological chemistry
2018-12-11 | Journal article
DOI: 10.1074/jbc.ra118.005179
PMID: 30538131
Source: Self-asserted source
Francoise Routier
grade
Preferred source (of 2)‎

Apicomplexan C-Mannosyltransferases Modify Thrombospondin Type I-containing Adhesins of the TRAP Family.

Glycobiology
2018-05-01 | Journal article
DOI: 10.1093/glycob/cwy013
PMID: 29432542
PMC: PMC6018953
Source: Self-asserted source
Francoise Routier
grade
Preferred source (of 2)‎

Parasite Glycobiology: A Bittersweet Symphony.

PLoS pathogens
2015-11-12 | Journal article
DOI: 10.1371/journal.ppat.1005169
PMID: 26562305
PMC: PMC4642930
Source: Self-asserted source
Francoise Routier
grade
Preferred source (of 2)‎

Depletion of UDP-Glucose and UDP-Galactose Using a Degron System Leads to Growth Cessation of Leishmania major.

PLoS neglected tropical diseases
2015-11-03 | Journal article
DOI: 10.1371/journal.pntd.0004205
PMID: 26529232
PMC: PMC4631452
Source: Self-asserted source
Francoise Routier
grade
Preferred source (of 2)‎

Aspergillus fumigatus Cap59-like protein A is involved in α1,3-mannosylation of GPI-anchors.

Glycobiology
2015-09-14 | Journal article
DOI: 10.1093/glycob/cwv078
PMID: 26369907
Source: Self-asserted source
Francoise Routier
grade
Preferred source (of 2)‎

Characterization of an N-acetylglucosaminyltransferase involved in Aspergillus fumigatus zwitterionic glycoinositolphosphoceramide biosynthesis.

Glycobiology
2015-08-24 | Journal article
DOI: 10.1093/glycob/cwv059
PMID: 26306635
Source: Self-asserted source
Francoise Routier
grade
Preferred source (of 2)‎

Identification, biochemical characterization, and in-vivo expression of the intracellular invertase BfrA from the pathogenic parasite Leishmania major.

Carbohydrate research
2015-07-26 | Journal article
DOI: 10.1016/j.carres.2015.07.001
PMID: 26279524
Source: Self-asserted source
Francoise Routier
grade
Preferred source (of 2)‎

Leishmania major UDP-sugar pyrophosphorylase salvages galactose for glycoconjugate biosynthesis.

International journal for parasitology
2015-07-26 | Journal article
DOI: 10.1016/j.ijpara.2015.06.004
PMID: 26215058
PMC: PMC4722067
Source: Self-asserted source
Francoise Routier
grade
Preferred source (of 2)‎

GDP-fucose transporter 1 (SLC35C1)

Handbook of Glycosyltransferases and Related Genes, Second Edition
2014 | Book chapter
Part of DOI: 10.1007/978-4-431-54240-7_38
EID:

2-s2.0-84999009432
Contributors: Bakker, H.; Ashikov, A.; Routier, F.H.; Gerardy-Schahn, R.
Source: Self-asserted source
Francoise Routier via Scopus - Elsevier

Catalytic mechanism and allosteric regulation of UDP-glucose pyrophosphorylase from Leishmania major

ACS Catalysis
2013 | Journal article
DOI: 10.1021/cs4007777
EID:

2-s2.0-84890369114

Part of ISSN: 21555435
Contributors: Führing, J.; Cramer, J.T.; Routier, F.H.; Lamerz, A.-C.; Baruch, P.; Gerardy-Schahn, R.; Fedorov, R.
Source: Self-asserted source
Francoise Routier via Scopus - Elsevier

Biosynthesis of the fungal cell wall polysaccharide galactomannan requires intraluminal GDP-mannose.

The Journal of biological chemistry
2012-11-08 | Journal article
DOI: 10.1074/jbc.M112.398321
PMID: 23139423
PMC: PMC3531755
Source: Self-asserted source
Francoise Routier
grade
Preferred source (of 2)‎

Towards the crystal structure elucidation of eukaryotic UDP-galactopyranose mutase.

Acta crystallographica. Section F, Structural biology and crystallization communications
2012-03-28 | Journal article
DOI: 10.1107/S1744309112006914
PMID: 22505419
PMC: PMC3325819
Source: Self-asserted source
Francoise Routier
grade
Preferred source (of 2)‎

Structural insight into the unique substrate binding mechanism and flavin redox state of UDP-galactopyranose mutase from Aspergillus fumigatus.

The Journal of biological chemistry
2012-02-10 | Journal article
DOI: 10.1074/jbc.M111.322974
PMID: 22334662
PMC: PMC3322874
Source: Self-asserted source
Francoise Routier
grade
Preferred source (of 2)‎

Direct investigation of the Aspergillus GDP-mannose transporter by STD NMR spectroscopy.

Chembiochem : a European journal of chemical biology
2011-09-23 | Journal article
DOI: 10.1002/cbic.201100483
PMID: 21953835
Source: Self-asserted source
Francoise Routier
grade
Preferred source (of 2)‎

Galactofuranose in eukaryotes: aspects of biosynthesis and functional impact.

Glycobiology
2011-09-22 | Journal article
DOI: 10.1093/glycob/cwr144
PMID: 21940757
Source: Self-asserted source
Francoise Routier
grade
Preferred source (of 2)‎

Studies on galactofuranose-containing glycostructures of the pathogenic mold Aspergillus fumigatus.

International journal of medical microbiology : IJMM
2011-05-20 | Journal article
DOI: 10.1016/j.ijmm.2011.02.003
PMID: 21601522
Source: Self-asserted source
Francoise Routier
grade
Preferred source (of 2)‎

Approaching the secrets of N-glycosylation in Aspergillus fumigatus: characterization of the AfOch1 protein.

PloS one
2010-12-29 | Journal article
DOI: 10.1371/journal.pone.0015729
PMID: 21206755
PMC: PMC3012087
Source: Self-asserted source
Francoise Routier
grade
Preferred source (of 2)‎

Structural basis for the broad substrate range of the UDP-sugar pyrophosphorylase from Leishmania major.

Journal of molecular biology
2010-11-10 | Journal article
DOI: 10.1016/j.jmb.2010.10.057
PMID: 21073876
Source: Self-asserted source
Francoise Routier
grade
Preferred source (of 2)‎

Farnesol misplaces tip-localized Rho proteins and inhibits cell wall integrity signalling in Aspergillus fumigatus.

Molecular microbiology
2010-04-14 | Journal article
DOI: 10.1111/j.1365-2958.2010.07170.x
PMID: 20398212
Source: Self-asserted source
Francoise Routier
grade
Preferred source (of 2)‎

Deletion of UDP-glucose pyrophosphorylase reveals a UDP-glucose independent UDP-galactose salvage pathway in Leishmania major.

Glycobiology
2010-03-24 | Journal article
DOI: 10.1093/glycob/cwq045
PMID: 20335578
PMC: PMC2900899
Source: Self-asserted source
Francoise Routier
grade
Preferred source (of 2)‎

Leishmania UDP-sugar pyrophosphorylase: the missing link in galactose salvage?

The Journal of biological chemistry
2009-11-11 | Journal article
DOI: 10.1074/jbc.M109.067223
PMID: 19906649
PMC: PMC2801289
Source: Self-asserted source
Francoise Routier
grade
Preferred source (of 2)‎

A single UDP-galactofuranose transporter is required for galactofuranosylation in Aspergillus fumigatus.

The Journal of biological chemistry
2009-10-19 | Journal article
DOI: 10.1074/jbc.M109.070219
PMID: 19840949
PMC: PMC2797156
Source: Self-asserted source
Francoise Routier
grade
Preferred source (of 2)‎

The mitA gene of Aspergillus fumigatus is required for mannosylation of inositol-phosphorylceramide, but is dispensable for pathogenicity.

Fungal genetics and biology : FG & B
2009-10-12 | Journal article
DOI: 10.1016/j.fgb.2009.10.001
PMID: 19822220
Source: Self-asserted source
Francoise Routier
grade
Preferred source (of 2)‎

The yeast oligosaccharyltransferase complex can be replaced by STT3 from Leishmania major.

Glycobiology
2008-10-25 | Journal article
DOI: 10.1093/glycob/cwn118
PMID: 18955371
Source: Self-asserted source
Francoise Routier
grade
Preferred source (of 2)‎

Contribution of galactofuranose to the virulence of the opportunistic pathogen Aspergillus fumigatus.

Eukaryotic cell
2008-06-13 | Journal article
DOI: 10.1128/EC.00109-08
PMID: 18552284
PMC: PMC2519766
Source: Self-asserted source
Francoise Routier
grade
Preferred source (of 2)‎

A CMP-sialic acid transporter cloned from Arabidopsis thaliana.

Carbohydrate research
2008-01-17 | Journal article
DOI: 10.1016/j.carres.2008.01.010
PMID: 18258224
Source: Self-asserted source
Francoise Routier
grade
Preferred source (of 2)‎

Targeted gene deletion of Leishmania major UDP-galactopyranose mutase leads to attenuated virulence.

The Journal of biological chemistry
2007-02-06 | Journal article
DOI: 10.1074/jbc.m700023200
PMID: 17284446
Source: Self-asserted source
Francoise Routier
grade
Preferred source (of 2)‎

Functional expression of the CMP-sialic acid transporter in Escherichia coli and its identification as a simple mobile carrier.

Glycobiology
2005-08-23 | Journal article
DOI: 10.1093/glycob/cwj029
PMID: 16118285
Source: Self-asserted source
Francoise Routier
grade
Preferred source (of 2)‎

Identification and partial characterization of two eukaryotic UDP-galactopyranose mutases.

Biological chemistry
2005-07-01 | Journal article
DOI: 10.1515/bc.2005.076
PMID: 16207086
Source: Self-asserted source
Francoise Routier
grade
Preferred source (of 2)‎

The human solute carrier gene SLC35B4 encodes a bifunctional nucleotide sugar transporter with specificity for UDP-xylose and UDP-N-acetylglucosamine.

The Journal of biological chemistry
2005-05-23 | Journal article
DOI: 10.1074/jbc.m504783200
PMID: 15911612
Source: Self-asserted source
Francoise Routier
grade
Preferred source (of 2)‎

Synthetic fragments of antigenic lipophosphoglycans from Leishmania major and Leishmania mexicana and their use for characterisation of the Leishmania elongating alpha-D-mannopyranosylphosphate transferase.

Chemistry (Weinheim an der Bergstrasse, Germany)
2005-03-01 | Journal article
DOI: 10.1002/chem.200400563
PMID: 15685582
Source: Self-asserted source
Francoise Routier
grade
Preferred source (of 2)‎

Molecular cloning of two Arabidopsis UDP-galactose transporters by complementation of a deficient Chinese hamster ovary cell line.

Glycobiology
2004-09-29 | Journal article
DOI: 10.1093/glycob/cwh159
PMID: 15456736
Source: Self-asserted source
Francoise Routier
grade
Preferred source (of 2)‎

Characterization of the elongating alpha-D-mannosyl phosphate transferase from three species of Leishmania using synthetic acceptor substrate analogues.

Biochemistry
2000-07-01 | Journal article
DOI: 10.1021/bi000371s
PMID: 10891083
Source: Self-asserted source
Francoise Routier
grade
Preferred source (of 2)‎

The preparation of neoglycoconjugates containing inter-saccharide phosphodiester linkages as potential anti-Leishmania vaccines.

Glycoconjugate journal
1999-12-01 | Journal article
DOI: 10.1023/a:1007171613195
PMID: 11133017
Source: Self-asserted source
Francoise Routier
grade
Preferred source (of 2)‎

Quantitation of the oligosaccharides of human serum IgG from patients with rheumatoid arthritis: a critical evaluation of different methods.

Journal of immunological methods
1998-04-01 | Journal article
DOI: 10.1016/s0022-1759(98)00032-5
PMID: 9692845
Source: Self-asserted source
Francoise Routier
grade
Preferred source (of 2)‎

Leishmania adleri, a lizard parasite, expresses structurally similar glycoinositolphospholipids to mammalian Leishmania.

Glycobiology
1997-07-01 | Journal article
DOI: 10.1093/glycob/7.5.687
PMID: 9254050
Source: Self-asserted source
Francoise Routier
grade
Preferred source (of 2)‎

1H NMR analysis of novel sialylated and fucosylated lactose-based oligosaccharides having linear GlcNAc(beta 1-6) Gal and Neu5Ac(alpha 2-6) GlcNAc sequences.

Carbohydrate research
1997-05-01 | Journal article
DOI: 10.1016/s0008-6215(96)00338-2
PMID: 9210297
Source: Self-asserted source
Francoise Routier
grade
Preferred source (of 2)‎

The glycosylation pattern of humanized IgGI antibody (D1.3) expressed in CHO cells.

Glycoconjugate journal
1997-02-01 | Journal article
DOI: 10.1023/a:1018589704981
PMID: 9111137
Source: Self-asserted source
Francoise Routier
grade
Preferred source (of 2)‎

Chemical characterisation of glycosylinositolphospholipids of Herpetomonas samuelpessoai.

Molecular and biochemical parasitology
1995-01-01 | Journal article
DOI: 10.1016/0166-6851(94)00202-x
PMID: 7723791
Source: Self-asserted source
Francoise Routier
grade
Preferred source (of 2)‎

Structure determination of phosphoinositol oligosaccharides from parasitic protozoa using fast atom bombardment mass spectrometry

Organic Mass Spectrometry
1994 | Journal article
DOI: 10.1002/oms.1210291209
EID:

2-s2.0-84989026591

Part of ISSN: 10969888 0030493X
Contributors: Wait, R.; Jones, C.; Routier, F.H.; Previato, J.O.; Mendonça‐Previato, L.
Source: Self-asserted source
Francoise Routier via Scopus - Elsevier

Structures of four oligosaccharides derived from the glycoinositolphospholipid of Leishmania adleri.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.]
1994 | Journal article
EID:

2-s2.0-0028379139

Part of ISSN: 0100879X
Contributors: Routier, F.; Mendonça-Previato, L.; Previato, J.O.; Jones, C.; Wait, R.
Source: Self-asserted source
Francoise Routier via Scopus - Elsevier
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