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SciProfiles: 545677

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Employment (1)

CNRS Délégation Bretagne et Pays de Loire: Rennes, Bretagne, FR

2001-09-15 to present | Research Engineer (Station Biologique de Roscoff)
Employment
Source: Self-asserted source
Stéphane Bach

Education and qualifications (2)

Université de Bretagne Occidentale: Brest, Bretagne, FR

2007 | Habilitation à Diriger des Recherches
Education
Source: Self-asserted source
Stéphane Bach

Faculté Universitaire des Sciences Agronomiques de Gembloux: Gembloux, BE

2000 | PhD Thesis
Education
Source: Self-asserted source
Stéphane Bach

Works (30)

Investigating the C2 Modulation of the Imidazo[1,2‐a]pyrazine‐Based Hit Compound CTN1122: Synthesis, in vitro Antileishmanial Activity, Cytotoxicity and Casein Kinase 1 Inhibition

ChemMedChem
2025-03-15 | Journal article
DOI: 10.1002/cmdc.202400862
Contributors: Lhana Tisseur; Sandrine Cojean; Khadidiatou Gassama; Cédric Logé; Fabrice Pagniez; Christian Cavé; Guillaume Bernadat; Philippe M. Loiseau; Stéphane Bach; Jérôme Thiéfaine et al.
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Crossref

On the Synthesis of [1,3]Azaphospholo[4,5‐f]quino(xa)lines and 2,3‐Dihydro‐[1,3]azaphospholo[4,5‐f]quino(xa)line 1‐oxides

European Journal of Organic Chemistry
2025-02-28 | Journal article
DOI: 10.1002/ejoc.202500080
Contributors: Mohamed Ali Dridi; Mohamed Hasyeoui; Frédéric Lassagne; William Erb; Charline Piroud; Thomas Robert; Stéphane Bach; Ali Samarat; Soufiane Touil; Florence Mongin
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The pyrazolo[4,3-c]pyrazole core as a novel and versatile scaffold for developing dual DYRK1A-CLK1 inhibitors targeting key processes of Alzheimer's disease pathology

European Journal of Medicinal Chemistry Reports
2024-12 | Journal article
DOI: 10.1016/j.ejmcr.2024.100193
Contributors: Vaia-Argyro Bakalakou; Barbara Mavroidi; Amalia D. Kalampaliki; Béatrice Josselin; Stéphane Bach; Alexios-Leandros Skaltsounis; Panagiotis Marakos; Nicole Pouli; Maria Pelecanou; Vassilios Myrianthopoulos et al.
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Crossref

Novel Thiazole-Fused [4,5-g] or [5,4-g]Quinazolin-8-ones and Their Quinazoline Analogues: Synthesis and Biological Evaluation

Pharmaceuticals
2024-10-30 | Journal article
DOI: 10.3390/ph17111452
Contributors: Nathan Broudic; Alexandra Pacheco-Benichou; Cécile Corbière; Blandine Baratte; Thomas Robert; Stéphane Bach; Hélène Solhi; Rémy Le Guével; Corinne Fruit; Thierry Besson
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New Fusarochromanone Derivatives from the Marine Fungus <i>Fusarium equiseti</i> UBOCC-A-117302

Marine Drugs
2024-09 | Journal article | Author
DOI: 10.3390/md22100444
Contributors: Giang Nam Pham; Béatrice Josselin; Arnaud Cousseau; Blandine BARATTE; Marie Dayras; Christophe Le Meur; Stella Debaets; Amélie Weill; Thomas Robert; Gaetan Burgaud et al.
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Multidisciplinary Digital Publishing Institute

Ethaverine and Papaverine Target Cyclin-Dependent Kinase 5 and Inhibit Lung Cancer Cell Proliferation and Migration

ACS Pharmacology & Translational Science
2024-05-10 | Journal article
DOI: 10.1021/acsptsci.4c00023
Contributors: Arthur Laure; Chloé Royet; Frederic Bihel; Blandine Baratte; Stéphane Bach; Marion Peyressatre; May C. Morris
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Crossref

From benzofuro-, benzothieno- and 10-methylindolo-[2,3-b]-fused benzothiopyrano[4,3,2-de]quinolines to the corresponding benzothiopyrano[4,3,2-de]1,8-naphthyridines: synthesis and properties of these hexacyclic heteroaromatic compounds

New Journal of Chemistry
2023 | Journal article
DOI: 10.1039/D2NJ04567B
Contributors: Nicolas Mast; William Erb; Lionel Nauton; Pascale Moreau; Olivier Mongin; Thierry Roisnel; Margaux Macaigne; Thomas Robert; Stéphane Bach; Laurent Picot et al.
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Quinazoline-based VEGFR-2 inhibitors as potential anti-angiogenic agents: A contemporary perspective of SAR and molecular docking studies

European Journal of Medicinal Chemistry
2023-11 | Journal article
DOI: 10.1016/j.ejmech.2023.115626
Contributors: Mahfam Moradi; Alireza Mousavi; Zahra Emamgholipour; Johanna Giovannini; Setareh Moghimi; Fariba Peytam; Amin Honarmand; Stéphane Bach; Alireza Foroumadi
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Crossref

Potassium 6-Oxo-7,13,16,22-tetraazatetracyclo[12.6.2.18,12.017,21]tricosa-1(20),8(23),9,11,14,16,18,21-octaen-2-yne-15-carboxylate

Molbank
2023-10-09 | Journal article
DOI: 10.3390/M1735
Contributors: Camille Blouet; Stéphanie Letast; Thomas Robert; Stéphane Bach; Noël Pinaud; Nicolas Joubert; Marie-Claude Viaud-Massuard; Jean Guillon; Cédric Logé; Caroline Denevault-Sabourin
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Potassium 6-oxo-7,13,16,22-tetraazatetracyclo[12.6.2.18,12.017,21]tricosa-1(20),8(23),9,11,14,16,18,21-octaen-2-yne-15-carboxylate

2023-09-11 | Preprint
DOI: 10.20944/preprints202309.0598.v1
Contributors: Camille Blouet; Stéphanie Letast; Thomas Robert; Stéphane Bach; Noël Pinaud; Nicolas Joubert; Marie-Claude Viaud-Massuard; Jean Guillon; Cédric Logé; Caroline Denevault-Sabourin
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Identification of Novel Compounds Inhibiting the Kinase Activity of the CDK5/p25 Complex via Direct Binding to p25

Biochemistry
2023-05-02 | Journal article
DOI: 10.1021/acs.biochem.2c00691
Contributors: Riheb Jabeur; Caroline Corbel; Pascal Loyer; Annabelle Le Parc; Adélaide Le Grand; Arnaud Comte; Stéphane Bach; Gwenaëlle André-Leroux; Olivier Sire; Hedi Ben Mansour et al.
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Crossref

An Optimized Workflow for the Discovery of New Antimicrobial Compounds Targeting Bacterial RNA Polymerase Complex Formation

Antibiotics
2022-10 | Journal article | Author
DOI: 10.3390/antibiotics11101449
Contributors: Alessia Caputo; Sara Sartini; Elisabetta Levati; Ilaria Minato; Gian Marco Elisi; Adriana Di Stasi; catherine guillou; Peter G. Goekjian; Pierre Garcia; David Gueyrard et al.
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Multidisciplinary Digital Publishing Institute

Practical approach to N-benzyl derivatives of 2-amino-8-methoxy-4H-chromene-3-carbonitrile by reductive amination: exploration of their effects against protein kinases and in silico ADME profiling

Journal of Molecular Structure
2022-10 | Journal article
DOI: 10.1016/j.molstruc.2022.134319
Contributors: Marwa Dhiabi; Ali Bouattour; Mehdi Fakhfakh; Souhir Abid; Ludovic Paquin; Thomas Robert; Stephane Bach; Jean-Pierre Bazureau; Houcine Ammar
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Crossref

Structure Activity Relationship Studies around DB18, a Potent and Selective Inhibitor of CLK Kinases

Molecules
2022-09-20 | Journal article
DOI: 10.3390/molecules27196149
Contributors: Dabbugoddu Brahmaiah; Anagani Kanaka Durga Bhavani; Pasula Aparna; Nangunoori Sampath Kumar; Hélène Solhi; Rémy Le Guevel; Blandine Baratte; Thomas Robert; Sandrine Ruchaud; Stéphane Bach et al.
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Dibenzofuran Derivatives Inspired from Cercosporamide as Dual Inhibitors of Pim and CLK1 Kinases

Molecules
2021-10-30 | Journal article
DOI: 10.3390/molecules26216572
Contributors: Viet Hung Dao; Isabelle Ourliac-Garnier; Cédric Logé; Florence O. McCarthy; Stéphane Bach; Teresinha Gonçalves da Silva; Caroline Denevault-Sabourin; Jérôme Thiéfaine; Blandine Baratte; Thomas Robert et al.
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Betulin, a Newly Characterized Compound in <i>Acacia auriculiformis</i> Bark, Is a Multi-Target Protein Kinase Inhibitor

Molecules
2021-07 | Journal article | Author
DOI: 10.3390/molecules26154599
Contributors: Augustine A. Ahmadu; Claire Delehouzé; Anas Haruna; Lukman Mustapha; Bilqis A. Lawal; Aniefiok Udobre; Blandine BARATTE; Camilla Triscornia; Axelle Autret; Thomas Robert et al.
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Multidisciplinary Digital Publishing Institute

New Quinoxaline Derivatives as Dual Pim-1/2 Kinase Inhibitors: Design, Synthesis and Biological Evaluation

Molecules
2021-02 | Journal article | Author
DOI: 10.3390/molecules26040867
Contributors: Bruno Oyallon; Marie Brachet-Botineau; cédric logé; Thomas Robert; Stéphane Bach; sajida IBRAHIM; William Raoul; Cécile Croix; Pascal Berthelot; Jean Guillon et al.
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Multidisciplinary Digital Publishing Institute
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From Synthetic Simplified Marine Metabolite Analogues to New Selective Allosteric Inhibitor of Aurora B Kinase

Journal of Medicinal Chemistry
2021-01-28 | Journal article
DOI: 10.1021/acs.jmedchem.0c02064
Contributors: Charlotte Juillet; Ludmila Ermolenko; Dina Boyarskaya; Blandine Baratte; Béatrice Josselin; Hristo Nedev; Stéphane Bach; Bogdan I. Iorga; Jérôme Bignon; Sandrine Ruchaud et al.
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From simple quinoxalines to potent oxazolo[5,4-f]quinoxaline inhibitors of glycogen-synthase kinase 3 (GSK3)

Organic & Biomolecular Chemistry
2020 | Journal article
DOI: 10.1039/C9OB02002K
Contributors: Frédéric Lassagne; Camille Duguépéroux; Carlos Roca; Concepcion Perez; Ana Martinez; Blandine Baratte; Thomas Robert; Sandrine Ruchaud; Stéphane Bach; William Erb et al.
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Crossref

Regorafenib analogues and their ferrocenic counterparts: synthesis and biological evaluation

New Journal of Chemistry
2020 | Journal article
DOI: 10.1039/D0NJ05334A
Contributors: Myron Wilde; Danielle Arzur; Blandine Baratte; Dorian Lefebvre; Thomas Robert; Thierry Roisnel; Catherine Le Jossic-Corcos; Stéphane Bach; Laurent Corcos; William Erb
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Crossref

Nigratine as first-in-class dual inhibitor of necroptosis and ferroptosis regulated cell death

2020-12-15 | Preprint
DOI: 10.1101/2020.12.15.422885
Contributors: Claire Delehouzé; Arnaud Comte; Marcelle Hauteville; Peter Goekjian; Marie-Thérèse Dimanche-Boitrel; Morgane Rousselot; Stéphane Bach
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Crossref

Kinase-Based Screening of Marine Natural Extracts Leads to the Identification of a Cytotoxic High Molecular Weight Metabolite from the Mediterranean Sponge <i>Crambe tailliezi</i>

Marine Drugs
2019-10 | Journal article | Author
DOI: 10.3390/md17100569
Contributors: Thi-Ngoc-Dung Nguyen; Omid Feizbakhsh; Estelle Sfecci; Blandine Baratte; Claire Delehouzé; Adrien Garcia; Corentin Moulin; Pierre Colas; Sandrine Ruchaud; Mohamed Mehiri et al.
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Multidisciplinary Digital Publishing Institute

New Antimicrobials Targeting Bacterial RNA Polymerase Holoenzyme Assembly Identified with an in Vivo BRET-Based Discovery Platform

ACS Chemical Biology
2019-08-16 | Journal article
DOI: 10.1021/acschembio.9b00178
Contributors: Sara Sartini; Elisabetta Levati; Martina Maccesi; Matteo Guerra; Gilberto Spadoni; Stéphane Bach; Monica Benincasa; Marco Scocchi; Simone Ottonello; Silvia Rivara et al.
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Crossref

Neurymenolide A, a Novel Mitotic Spindle Poison from the New Caledonian Rhodophyta <i>Phacelocarpus neurymenioides</i>

Marine Drugs
2019-02 | Journal article | Author
DOI: 10.3390/md17020093
Contributors: Sofia-Eléna Motuhi; Omid Feizbakhsh; Béatrice Foll-Josselin; Blandine BARATTE; Claire Delehouzé; Arnaud Cousseau; Xavier Fant; Jeannette Chloë Bulinski; Claude Elisabeth Payri; Sandrine Ruchaud et al.
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Multidisciplinary Digital Publishing Institute

The Anti-<i>Candida albicans</i> Agent 4-AN Inhibits Multiple Protein Kinases

Molecules
2019-01 | Journal article | Author
DOI: 10.3390/molecules24010153
Contributors: Maciej Masłyk; Monika Janeczko; Aleksandra Martyna; Sławomir Czernik; Małgorzata Tokarska-Rodak; Marta Chwedczuk; Béatrice Foll-Josselin; Sandrine Ruchaud; Stéphane Bach; Oleg M. Demchuk et al.
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Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

From Quinoxaline, Pyrido[2,3-<i>b</i>]pyrazine and Pyrido[3,4-<i>b</i>]pyrazine to Pyrazino-Fused Carbazoles and Carbolines

Molecules
2018-11 | Journal article | Author
DOI: 10.3390/molecules23112961
Contributors: Frédéric Lassagne; Timothy Langlais; Elsa Caytan; Emmanuelle Limanton; Ludovic Paquin; Manon BOULLARD; Coline Courtel; Idriss Curbet; Clément Gédéon; Julien Lebreton et al.
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Multidisciplinary Digital Publishing Institute

Bioactive Metabolites from the Deep Subseafloor Fungus Oidiodendron griseum UBOCC-A-114129

Marine Drugs
2017-04-07 | Journal article
DOI: 10.3390/md15040111
Contributors: Marion Navarri; Camille Jégou; Arnaud Bondon; Sandrine Pottier; Stéphane Bach; Blandine Baratte; Sandrine Ruchaud; Georges Barbier; Gaëtan Burgaud; Yannick Fleury
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Crossref

Marine Natural Products from New Caledonia—A Review

Marine Drugs
2016-03-16 | Journal article
DOI: 10.3390/md14030058
Contributors: Sofia-Eléna Motuhi; Mohamed Mehiri; Claude Payri; Stéphane La Barre; Stéphane Bach
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Crossref

Bioprospecting Marine Plankton

Marine Drugs
2013-11-14 | Journal article
DOI: 10.3390/md11114594
Contributors: Heni Abida; Sandrine Ruchaud; Laurent Rios; Anne Humeau; Ian Probert; Colomban De Vargas; Stéphane Bach; Chris Bowler
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Crossref

Betulin, a Newly Characterized Compound in Acacia Auriculiformis Bark, is a Multi-target Protein Kinase Inhibitor
Source: check_circle
Multidisciplinary Digital Publishing Institute
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