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A gene risk score using missense variants in SLCO1B1 is associated with earlier onset statin intolerance

European Heart Journal - Cardiovascular Pharmacotherapy
2023-09-20 | Journal article
DOI: 10.1093/ehjcvp/pvad040
Contributors: Margherita Bigossi; Cyrielle Maroteau; Adem Y Dawed; Alasdair Taylor; Sundararajan Srinivasan; Alaa’ Lufti Melhem; Ewan R Pearson; Roberto Pola; Colin N A Palmer; Moneeza K Siddiqui
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Crossref

The cholesterol-lowering effect of statins is modified by LILRB5 intolerance genotype: Results from a recruit-by-genotype clinical trial

Frontiers in Pharmacology
2023-03-14 | Journal article
DOI: 10.3389/fphar.2023.1090010
Part of ISSN: 1663-9812
Contributors: Aleksi Tornio; Margherita Bigossi; Moneeza K. Siddiqui; Gwen Kennedy; Ala’a Melhem; Mehul K. Chourasia; Cyrielle Maroteau; Roberto Pola; Daniel I. Chasman; Alexander S. F. Doney et al.
Source: Self-asserted source
Alaa' Lutfi Melhem

Common and rare variants in SLCO1B1 are associated with statin intolerance

2022-08-10 | Preprint
DOI: 10.1101/2022.08.09.22278584
Contributors: Margherita Bigossi; Cyrielle Maroteau; Adem Y Dawed; Alasdair Taylor; Sundararajan Srinivasan; Alaa’ Lufti Melhem; Ewan R Pearson; Roberto Pola; Colin N A Palmer; Moneeza K Siddiqui
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Crossref

Common Statin Intolerance Variants in ABCB1 and LILRB5 Show Synergistic Effects on Statin Response: An Observational Study Using Electronic Health Records

2021 | Journal article
URI:

https://doi.org/10.3389/fgene.2021.713181
Source: Self-asserted source
Alaa' Lutfi Melhem

Data_Sheet_1_Common Statin Intolerance Variants in ABCB1 and LILRB5 Show Synergistic Effects on Statin Response: An Observational Study Using Electronic Health Records.docx

2021 | Other
URI:

https://doi.org/10.3389/fgene.2021.713181.s001
Source: Self-asserted source
Alaa' Lutfi Melhem
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