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University of Michigan: Ann Arbor, MI, US

2017-09-01 to present | Assistant Professor (Chemistry)
Employment
Source: Self-asserted source
Jennifer Bridwell-Rabb

Works (26)

Chlorophyllase from Arabidopsis thaliana Reveals an Emerging Model for Controlling Chlorophyll Hydrolysis

ACS Bio & Med Chem Au
2024-12-18 | Journal article
DOI: 10.1021/acsbiomedchemau.4c00089
Contributors: Madison Knapp; Minshik Jo; Courtney L. Henthorn; Marley Brimberry; Andrew D. Gnann; Daniel P. Dowling; Jennifer Bridwell-Rabb
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Crossref

Conformation-Dependent Hydrogen-Bonding Interactions in a Switchable Artificial Metalloprotein

Biochemistry
2024-08-20 | Journal article
DOI: 10.1021/acs.biochem.4c00209
Contributors: Saman Fatima; Behzad Mehrafrooz; David G. Boggs; Noor Ali; Swapnil Singh; Megan C. Thielges; Jennifer Bridwell-Rabb; Aleksei Aksimentiev; Lisa Olshansky
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Crossref

Structure-driven development of a biomimetic rare earth artificial metalloprotein

Proceedings of the National Academy of Sciences
2024-08-13 | Journal article
DOI: 10.1073/pnas.2405836121
Contributors: Peter J. Thompson; David G. Boggs; Charles A. Wilson; Austin T. Bruchs; Uditha Velidandla; Jennifer Bridwell-Rabb; Lisa Olshansky
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Crossref

Custom tuning of Rieske oxygenase reactivity

Nature Communications
2023-09-20 | Journal article
DOI: 10.1038/s41467-023-41428-x
Contributors: Jiayi Tian; Jianxin Liu; Madison Knapp; Patrick H. Donnan; David G. Boggs; Jennifer Bridwell-Rabb
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Crossref

Leveraging a Structural Blueprint to Rationally Engineer the Rieske Oxygenase TsaM

Biochemistry
2023-06-06 | Journal article
DOI: 10.1021/acs.biochem.3c00150
Contributors: Jiayi Tian; Alejandro Arcadio Garcia; Patrick H. Donnan; Jennifer Bridwell-Rabb
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Crossref

Engineering Rieske oxygenase activity one piece at a time

Current Opinion in Chemical Biology
2023-02 | Journal article
DOI: 10.1016/j.cbpa.2022.102227
Contributors: Marley Brimberry; Alejandro Arcadio Garcia; Jianxin Liu; Jiayi Tian; Jennifer Bridwell-Rabb
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Crossref

Engineering a Conformationally Switchable Artificial Metalloprotein

Journal of the American Chemical Society
2022-11-30 | Journal article
DOI: 10.1021/jacs.2c08885
Contributors: Saman Fatima; David G. Boggs; Noor Ali; Peter J. Thompson; Megan C. Thielges; Jennifer Bridwell-Rabb; Lisa Olshansky
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Crossref

Rieske Oxygenase Catalyzed C–H Bond Functionalization Reactions in Chlorophyll b Biosynthesis

ACS Central Science
2022-10-26 | Journal article
DOI: 10.1021/acscentsci.2c00058
Contributors: Jianxin Liu; Madison Knapp; Minshik Jo; Zerick Dill; Jennifer Bridwell-Rabb
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Crossref

Cobalamin-Dependent Radical S-Adenosylmethionine Enzymes: Capitalizing on Old Motifs for New Functions

ACS Bio & Med Chem Au
2022-06-15 | Journal article
DOI: 10.1021/acsbiomedchemau.1c00051
Contributors: Jennifer Bridwell-Rabb; Bin Li; Catherine L. Drennan
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Crossref

Structural and mechanistic basis for redox sensing by the cyanobacterial transcription regulator RexT

Communications Biology
2022-03-28 | Journal article
DOI: 10.1038/s42003-022-03226-x
Contributors: Bin Li; Minshik Jo; Jianxin Liu; Jiayi Tian; Robert Canfield; Jennifer Bridwell-Rabb
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Crossref

Design principles for site-selective hydroxylation by a Rieske oxygenase

Nature Communications
2022-01-11 | Journal article
DOI: 10.1038/s41467-021-27822-3
Contributors: Jianxin Liu; Jiayi Tian; Christopher Perry; April L. Lukowski; Tzanko I. Doukov; Alison R. H. Narayan; Jennifer Bridwell-Rabb
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Crossref

Structural basis for divergent C–H hydroxylation selectivity in two Rieske oxygenases

Nature Communications
2020-06-12 | Journal article
DOI: 10.1038/s41467-020-16729-0
Contributors: April L. Lukowski; Jianxin Liu; Jennifer Bridwell-Rabb; Alison R. H. Narayan
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Crossref

Functional Annotation of ABHD14B, an Orphan Serine Hydrolase Enzyme

Biochemistry
2020-01-21 | Journal article
DOI: 10.1021/acs.biochem.9b00703
Contributors: Abinaya Rajendran; Kaveri Vaidya; Johnny Mendoza; Jennifer Bridwell-Rabb; Siddhesh S. Kamat
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Crossref

Mechanism of frataxin “bypass” in human iron–sulfur cluster biosynthesis with implications for Friedreich’s ataxia

Journal of Biological Chemistry
2019-06 | Journal article
DOI: 10.1074/jbc.RA119.007716
Contributors: Deepika Das; Shachin Patra; Jennifer Bridwell-Rabb; David P. Barondeau
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Crossref

Aerobic Enzymes and Their Radical SAM Enzyme Counterparts in Tetrapyrrole Pathways

Biochemistry
2019-01-15 | Journal article
DOI: 10.1021/acs.biochem.8b00906
Contributors: Bin Li; Jennifer Bridwell-Rabb
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Crossref
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A Rich Man, Poor Man Story of S-Adenosylmethionine and Cobalamin Revisited

Annual Review of Biochemistry
2018-06 | Journal article
DOI: 10.1146/annurev-biochem-062917-012500
Part of ISSN: 0066-4154
Contributors: Jennifer Bridwell-Rabb; Tsehai A.J. Grell; Catherine L. Drennan
Source: Self-asserted source
Jennifer Bridwell-Rabb via Crossref Metadata Search

Vitamin B 12 in the spotlight again

Current Opinion in Chemical Biology
2017-04 | Journal article
DOI: 10.1016/j.cbpa.2017.01.013
Part of ISSN: 1367-5931
Contributors: Jennifer Bridwell-Rabb; Catherine L Drennan
Source: Self-asserted source
Jennifer Bridwell-Rabb via Crossref Metadata Search

A B12-dependent radical SAM enzyme involved in oxetanocin A biosynthesis

Nature
2017-03 | Journal article
DOI: 10.1038/nature21689
Part of ISSN: 0028-0836
Contributors: Jennifer Bridwell-Rabb; Aoshu Zhong; He G. Sun; Catherine L. Drennan; Hung-wen Liu
Source: Self-asserted source
Jennifer Bridwell-Rabb via Crossref Metadata Search

An HD domain phosphohydrolase active site tailored for oxetanocin-A biosynthesis

Proceedings of the National Academy of Sciences
2016-11 | Journal article
DOI: 10.1073/pnas.1613610113
Part of ISSN: 0027-8424
Contributors: Jennifer Bridwell-Rabb; Gyunghoon Kang; Aoshu Zhong; Hung-wen Liu; Catherine L. Drennan
Source: Self-asserted source
Jennifer Bridwell-Rabb via Crossref Metadata Search

A radically unexpected mechanism

Science
2016-03 | Journal article
DOI: 10.1126/science.aaf4942
Part of ISSN: 0036-8075
Contributors: J. Bridwell-Rabb; C. L. Drennan
Source: Self-asserted source
Jennifer Bridwell-Rabb via Crossref Metadata Search

Metalloprotein Crystallography: More than a Structure

Accounts of Chemical Research
2016-03 | Journal article
DOI: 10.1021/acs.accounts.5b00538
Part of ISSN: 0001-4842
Contributors: Sarah E. J. Bowman; Jennifer Bridwell-Rabb; Catherine L. Drennan
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Jennifer Bridwell-Rabb via Crossref Metadata Search

Human Frataxin Activates Fe–S Cluster Biosynthesis by Facilitating Sulfur Transfer Chemistry

Biochemistry
2014-07 | Journal article
DOI: 10.1021/bi500532e
Part of ISSN: 0006-2960
Contributors: Jennifer Bridwell-Rabb; Nicholas G. Fox; Chi-Lin Tsai; Andrew M. Winn; David P. Barondeau
Source: Self-asserted source
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Effector Role Reversal during Evolution: The Case of Frataxin in Fe–S Cluster Biosynthesis

Biochemistry
2012-03 | Journal article
DOI: 10.1021/bi201628j
Part of ISSN: 0006-2960
Contributors: Jennifer Bridwell-Rabb; Clara Iannuzzi; Annalisa Pastore; David P. Barondeau
Source: Self-asserted source
Jennifer Bridwell-Rabb via Crossref Metadata Search

Structure–Function Analysis of Friedreich’s Ataxia Mutants Reveals Determinants of Frataxin Binding and Activation of the Fe–S Assembly Complex

Biochemistry
2011-08 | Journal article
DOI: 10.1021/bi200895k
Part of ISSN: 0006-2960
Contributors: Jennifer Bridwell-Rabb; Andrew M. Winn; David P. Barondeau
Source: Self-asserted source
Jennifer Bridwell-Rabb via Crossref Metadata Search

Friedreich’s Ataxia Variants I154F and W155R Diminish Frataxin-Based Activation of the Iron–Sulfur Cluster Assembly Complex

Biochemistry
2011-07 | Journal article
DOI: 10.1021/bi200666h
Part of ISSN: 0006-2960
Contributors: Chi-Lin Tsai; Jennifer Bridwell-Rabb; David P. Barondeau
Source: Self-asserted source
Jennifer Bridwell-Rabb via Crossref Metadata Search

The KaiA protein of the cyanobacterial circadian oscillator is modulated by a redox-active cofactor

Proceedings of the National Academy of Sciences
2010-03 | Journal article
DOI: 10.1073/pnas.0910141107
Part of ISSN: 0027-8424
Contributors: T. L. Wood; J. Bridwell-Rabb; Y.-I. Kim; T. Gao; Y.-G. Chang; A. LiWang; D. P. Barondeau; S. S. Golden
Source: Self-asserted source
Jennifer Bridwell-Rabb via Crossref Metadata Search

Peer review (30 reviews for 10 publications/grants)

Review activity for ACS catalysis. (1)
Review activity for ACS central science. (1)
Review activity for ACS chemical biology. (1)
Review activity for Analytical chemistry. (1)
Review activity for Biochemistry. (11)
Review activity for ChemBioChem. (1)
Review activity for Journal of the American Chemical Society. (6)
Review activity for Nature (2)
Review activity for Nature chemical biology. (1)
Review activity for Nature communications (5)
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