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Works (41)

Corticosteroid-triggered acute skeletal muscle loss in lipodystrophy: A case report

Journal of Diabetes Investigation
2024 | Journal article
DOI: 10.1111/JDI.14158
WOSUID: WOS:001164450700001
Contributors: Sasako, Takayoshi; Suzuki, Ken; Odawara, Sara; Suwanai, Hirotsugu; Akuta, Naoko; Kubota, Naoto; Ueki, Kohjiro; Kadowaki, Takashi; Yamauchi, Toshimasa
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Exploring mechanisms of insulin action and strategies to treat diabetes

Endocrine Journal
2024 | Journal article
DOI: 10.1507/ENDOCRJ.EJ24-0003
WOSUID: WOS:001235312600001
Contributors: Sasako, Takayoshi
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Exploring mechanisms underlying diabetes comorbidities and strategies to prevent vascular complications

Diabetology International
2024 | Journal article
DOI: 10.1007/S13340-023-00677-3
WOSUID: WOS:001126283700001
Contributors: Sasako, Takayoshi
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Overexpression of UBE2E2 in Mouse Pancreatic β-Cells Leads to Glucose Intolerance via Reduction of β-Cell Mass

Diabetes
2024 | Journal article
DOI: 10.2337/DB23-0150
WOSUID: WOS:001181383500017
Contributors: Sakurai, Yoshitaka; Kubota, Naoto; Takamoto, Iseki; Wada, Nobuhiro; Aihara, Masakazu; Hayashi, Takanori; Kubota, Tetsuya; Hiraike, Yuta; Sasako, Takayoshi; Nakao, Harumi et al.
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The Influence of Trinucleotide Repeats in the Androgen Receptor Gene on Androgen-related Traits and Diseases

The Journal of Clinical Endocrinology & Metabolism
2024 | Journal article
DOI: 10.1210/CLINEM/DGAE302
WOSUID: WOS:001229687200001
Contributors: Sasako, Takayoshi; Ilboudo, Yann; Liang, Kevin Y. H.; Chen, Yiheng; Yoshiji, Satoshi; Richards, J. Brent
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The performance of AlphaMissense to identify genes causing disease

MedRxiv
2024 | Journal article
DOI: 10.1101/2024.03.05.24303647
WOSUID: PPRN:88050110
Contributors: Chen, Yiheng; Butler-Laporte, Guillaume; Liang, Kevin Y. H; Ilboudo, Yann; Yasmeen, Summaira; Sasako, Takayoshi; Langenberg, Claudia; Greenwood, Celia M.T.; Richards, J Brent
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COL6A3-derived endotrophin mediates the effect of obesity on coronary artery disease: an integrative proteogenomics analysis

MedRxiv
2023 | Journal article
DOI: 10.1101/2023.04.19.23288706
WOSUID: PPRN:65333770
Contributors: Yoshiji, Satoshi; Lu, Tianyuan; Butler-Laporte, Guillaume; Carrasco-Zanini-Sanchez, Julia; Chen, Yiheng; Liang, Kevin; Willett, Julian Daniel Sunday; Su, Chen-Yang; Wang, Shidong; Adra, Darin et al.
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Gut insulin action protects from hepatocarcinogenesis in diabetic mice comorbid with nonalcoholic steatohepatitis

Nature Communications
2023 | Journal article
DOI: 10.1038/S41467-023-42334-Y
WOSUID: WOS:001100768000023
Contributors: Soeda, Kotaro; Sasako, Takayoshi; Enooku, Kenichiro; Kubota, Naoto; Kobayashi, Naoki; Ikushima, Yoshiko Matsumoto; Awazawa, Motoharu; Bouchi, Ryotaro; Toda, Gotaro; Yamada, Tomoharu et al.
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Intensified Multifactorial Intervention in Patients with Type 2 Diabetes Mellitus

Diabetes & Metabolism Journal
2023 | Journal article
DOI: 10.4093/DMJ.2022.0325
WOSUID: WOS:000954551300004
Contributors: Sasako, Takayoshi; Yamauchi, Toshimasa; Ueki, Kohjiro
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Sarcopenia phenotype and impaired muscle function in male mice with fast-twitch muscle-specific knockout of the androgen receptor

Proceedings of the National Academy of Sciences
2023 | Journal article
DOI: 10.1073/PNAS.2218032120
WOSUID: WOS:001015120500003
Contributors: Hosoi, Tatsuya; Yakabe, Mitsutaka; Sasakawa, Hiroko; Sasako, Takayoshi; Ueki, Kohjiro; Kato, Shigeaki; Tokuoka, Suzumi M.; Oda, Yoshiya; Abe, Masahiro; Matsumoto, Toshio et al.
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Sarcopenia: Loss of mighty armor against frailty and aging

Journal of Diabetes Investigation
2023 | Journal article
DOI: 10.1111/JDI.14067
WOSUID: WOS:001044316800001
Contributors: Sasako, Takayoshi; Ueki, Kohjiro
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Addressing screams for evidence on renoprotection by GLP-1 receptor agonists

Kidney International
2022 | Journal article
DOI: 10.1016/J.KINT.2021.11.021
WOSUID: WOS:000746612100008
Contributors: Sasako, Takayoshi; Yamauchi, Toshimasa
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Deletion of skeletal muscle <i>Akt1</i>/<i>2</i> causes osteosarcopenia and reduces lifespan in mice

Nature Communications
2022 | Journal article
DOI: 10.1038/S41467-022-33008-2
WOSUID: WOS:000864193100005
Contributors: Sasako, Takayoshi; Umehara, Toshihiro; Soeda, Kotaro; Kaneko, Kazuma; Suzuki, Miho; Kobayashi, Naoki; Okazaki, Yukiko; Tamura-Nakano, Miwa; Chiba, Tomoki; Accili, Domenico et al.
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Severe aortic stenosis during leptin replacement therapy in a patient with generalized lipodystrophy-associated progeroid syndrome due to an <i>LMNA</i> variant: A case report

Journal of Diabetes Investigation
2022 | Journal article
DOI: 10.1111/JDI.13827
WOSUID: WOS:000809265800001
Contributors: Sasako, Takayoshi; Kadowaki, Hiroko; Fujiwara, Takayuki; Kodera, Satoshi; Komuro, Issei; Kadowaki, Takashi; Yamauchi, Toshimasa
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Skeletal muscle mitoribosomal defects are linked to low bone mass caused by bone marrow inflammation in male mice

Journal of Cachexia, Sarcopenia and Muscle
2022 | Journal article
DOI: 10.1002/JCSM.12975
WOSUID: WOS:000770782500001
Contributors: Tian, Jingwen; Chung, Hyo Kyun; Moon, Ji Sun; Nga, Ha Thi; Lee, Ho Yeop; Kim, Jung Tae; Chang, Joon Young; Kang, Seul Gi; Ryu, Dongryeol; Che, Xiangguo et al.
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Adaptive Response as a Potential Key Link Between SGLT2 Inhibition and Renoprotection

Kidney International Reports
2021 | Journal article
DOI: 10.1016/J.EKIR.2021.05.035
WOSUID: WOS:000684577400005
Contributors: Sasako, Takayoshi; Tanaka, Tetsuhiro; Yamauchi, Toshimasa
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Effect of a Multifactorial Intervention on Fracture in Patients With Type 2 Diabetes: Subanalysis of the J-DOIT3 Study

The Journal of Clinical Endocrinology & Metabolism
2021 | Journal article
DOI: 10.1210/CLINEM/DGAB013
WOSUID: WOS:000658260400017
Contributors: Sasako, Takayoshi; Ueki, Kohjiro; Miyake, Kana; Okazaki, Yukiko; Takeuchi, Yasuhiro; Ohashi, Yasuo; Noda, Mitsuhiko; Kadowaki, Takashi
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Hepatocellular carcinoma development in diabetic patients: a nationwide survey in Japan

Journal of Gastroenterology
2021 | Journal article
DOI: 10.1007/S00535-020-01754-Z
WOSUID: WOS:000607037700001
Contributors: Tateishi, Ryosuke; Matsumura, Takeshi; Okanoue, Takeshi; Shima, Toshihide; Uchino, Koji; Fujiwara, Naoto; Senokuchi, Takafumi; Kon, Kazuyoshi; Sasako, Takayoshi; Taniai, Makiko et al.
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Multifactorial intervention has a significant effect on diabetic kidney disease in patients with type 2 diabetes

Kidney International
2021 | Journal article
DOI: 10.1016/J.KINT.2020.08.012
WOSUID: WOS:000610556500031
Contributors: Ueki, Kohjiro; Sasako, Takayoshi; Okazaki, Yukiko; Miyake, Kana; Nangaku, Masaomi; Ohashi, Yasuo; Noda, Mitsuhiko; Kadowaki, Takashi
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Clinical usefulness of multigene screening with phenotype-driven bioinformatics analysis for the diagnosis of patients with monogenic diabetes or severe insulin resistance

Diabetes Research and Clinical Practice
2020 | Journal article
DOI: 10.1016/J.DIABRES.2020.108461
WOSUID: WOS:000598123600012
Contributors: Hosoe, Jun; Miya, Fuyuki; Kadowaki, Hiroko; Fujiwara, Toyofumi; Suzuki, Ken; Kato, Takashi; Waki, Hironori; Sasako, Takayoshi; Aizu, Katsuya; Yamamura, Natsumi et al.
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Hepatic FATP5 expression is associated with histological progression and loss of hepatic fat in NAFLD patients

Journal of Gastroenterology
2020 | Journal article
DOI: 10.1007/S00535-019-01633-2
WOSUID: WOS:000512003100009
Contributors: Enooku, Kenichiro; Tsutsumi, Takeya; Kondo, Mayuko; Fujiwara, Naoto; Sasako, Takayoshi; Shibahara, Junji; Kado, Akira; Okushin, Kazuya; Fujinaga, Hidetaka; Nakagomi, Ryo et al.
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Insulin- and Lipopolysaccharide-Mediated Signaling in Adipose Tissue Macrophages Regulates Postprandial Glycemia through Akt-mTOR Activation

Molecular Cell
2020 | Journal article
DOI: 10.1016/J.MOLCEL.2020.04.033
WOSUID: WOS:000548786000006
Contributors: Toda, Gotaro; Soeda, Kotaro; Okazaki, Yukiko; Kobayashi, Naoki; Masuda, Yukari; Arakawa, Naoko; Suwanai, Hirotsugu; Masamoto, Yosuke; Izumida, Yoshihiko; Kamei, Nozomu et al.
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Skeletal muscle mitochondrial dysfunction in mice is linked to bone loss via the bone marrow immune microenvironment

bioRxiv
2020 | Other
DOI: 10.1101/2020.12.09.417147
EID:

2-s2.0-85099895169

Part of ISSN: 26928205
Contributors: Tian, J.; Moon, J.S.; Nga, H.T.; Chung, H.K.; Lee, H.Y.; Kim, J.T.; Chang, J.Y.; Kang, S.G.; Ryu, D.; Che, X. et al.
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Takayoshi Sasako via Scopus - Elsevier

ADDITION-Europe: the first decade and beyond

The Lancet Diabetes & Endocrinology
2019 | Journal article
DOI: 10.1016/S2213-8587(19)30347-X
WOSUID: WOS:000497977100006
Contributors: Sasako, Takayoshi; Kadowaki, Takashi; Ueki, Kohjiro
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Effect of Multifactorial Intervention on Diabetic Kidney Disease in Patients with Type 2 Diabetes

SSRN
2019 | Other
DOI: 10.2139/ssrn.3409298
EID:

2-s2.0-85111460250

Part of ISSN: 15565068
Contributors: Ueki, K.; Sasako, T.; Okazaki, Y.; Miyake, K.; Nangaku, M.; Ohashi, Y.; Noda, M.; Kadowaki, T.
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Takayoshi Sasako via Scopus - Elsevier

Effectiveness of Comprehensive Gene Panel-Based Next-Generation Sequencing with Phenotype-Driven Bioinformatics Analysis for Diagnosis of Atypical Diabetes

Diabetes
2019 | Journal article
DOI: 10.2337/DB19-1325-P
WOSUID: WOS:000501366903209
Contributors: Hosoe, Jun; Kadowaki, Hiroko; Miya, Fuyuki; Takakura, Minaka; Waki, Hironori; Sasako, Takayoshi; Kato, Takashi; Tsunoda, Tatsuhiko; Shojima, Nobuhiro; Yamauchi, Toshimasa et al.
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Hepatic Sdf2l1 controls feeding-induced ER stress and regulates metabolism

Nature Communications
2019 | Journal article
DOI: 10.1038/S41467-019-08591-6
WOSUID: WOS:000459802500001
Contributors: Sasako, Takayoshi; Ohsugi, Mitsuru; Kubota, Naoto; Itoh, Shinsuke; Okazaki, Yukiko; Terai, Ai; Kubota, Tetsuya; Yamashita, Satoshi; Nakatsukasa, Kunio; Kamura, Takumi et al.
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Robust and highly efficient hiPSC generation from patient non-mobilized peripheral blood-derived CD34<SUP>+</SUP> cells using the auto-erasable Sendai virus vector

Stem Cell Research & Therapy
2019 | Journal article
DOI: 10.1186/S13287-019-1273-2
WOSUID: WOS:000472941700003
Contributors: Okumura, Takashi; Horie, Yumi; Lai, Chen-Yi; Lin, Huan-Ting; Shoda, Hirofumi; Natsumoto, Bunki; Fujio, Keishi; Kumaki, Eri; Okano, Tsubasa; Ono, Shintaro et al.
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Variation in process quality measures of diabetes care by region and institution in Japan during 2015-2016: An observational study of nationwide claims data

Diabetes Research and Clinical Practice
2019 | Journal article
DOI: 10.1016/J.DIABRES.2019.05.029
WOSUID: WOS:000487832100028
Contributors: Sugiyama, Takehiro; Imai, Kenjiro; Ihana-Sugiyama, Noriko; Tanaka, Hirokazu; Yanagisawa-Sugita, Ayako; Sasako, Takayoshi; Higashi, Takahiro; Okamura, Tomonori; Yamauchi, Toshimasa; Ueki, Kohjiro et al.
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Hepatic IRS1 and β-catenin expression is associated with histological progression and overt diabetes emergence in NAFLD patients

Journal of Gastroenterology
2018 | Journal article
DOI: 10.1007/S00535-018-1472-0
WOSUID: WOS:000450128700004
Contributors: Enooku, Kenichiro; Kondo, Mayuko; Fujiwara, Naoto; Sasako, Takayoshi; Shibahara, Junji; Kado, Akira; Okushin, Kazuya; Fujinaga, Hidetaka; Tsutsumi, Takeya; Nakagomi, Ryo et al.
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The RNA Methyltransferase Complex of WTAP, METTL3, and METTL14 Regulates Mitotic Clonal Expansion in Adipogenesis

Molecular and Cellular Biology
2018 | Journal article
DOI: 10.1128/MCB.00116-18
WOSUID: WOS:000440136900004
Contributors: Kobayashi, Masatoshi; Ohsugi, Mitsuru; Sasako, Takayoshi; Awazawa, Motoharu; Umehara, Toshihiro; Iwane, Aya; Kobayashi, Naoki; Okazaki, Yukiko; Kubota, Naoto; Suzuki, Ryo et al.
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Dual Regulation of Gluconeogenesis by Insulin and Glucose in the Proximal Tubules of the Kidney

Diabetes
2017 | Journal article
DOI: 10.2337/DB16-1602
WOSUID: WOS:000408156600004
Contributors: Sasaki, Motohiro; Sasako, Takayoshi; Kubota, Naoto; Sakurai, Yoshitaka; Takamoto, Iseki; Kubota, Tetsuya; Inagi, Reiko; Seki, George; Goto, Moritaka; Ueki, Kohjiro et al.
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Effect of an intensified multifactorial intervention on cardiovascular outcomes and mortality in type 2 diabetes (J-DOIT3): an open-label, randomised controlled trial

The Lancet Diabetes & Endocrinology
2017 | Journal article
DOI: 10.1016/S2213-8587(17)30327-3
WOSUID: WOS:000416514700017
Contributors: Ueki, Kohjiro; Sasako, Takayoshi; Okazaki, Yukiko; Kato, Masayuki; Okahata, Sumie; Katsuyama, Hisayuki; Haraguchi, Mikiko; Morita, Ai; Ohashi, Ken; Hara, Kazuo et al.
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Willingness of patients with diabetes to use an ICT-based self-management tool: a cross-sectional study

BMJ Open Diabetes Research & Care
2017 | Journal article
DOI: 10.1136/BMJDRC-2016-000322
WOSUID: WOS:000397037300014
Contributors: Shibuta, Tomomi; Waki, Kayo; Tomizawa, Nobuko; Igarashi, Ayumi; Yamamoto-Mitani, Noriko; Yamaguchi, Satoko; Fujita, Hideo; Kimura, Shigeko; Fujiu, Katsuhito; Waki, Hironori et al.
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Design of and rationale for the Japan Diabetes Optimal Integrated Treatment study for 3 major risk factors of cardiovascular diseases (J-DOIT3): a multicenter, open-label, randomized, parallel-group trial

BMJ Open Diabetes Research & Care
2016 | Journal article
DOI: 10.1136/BMJDRC-2015-000123
WOSUID: WOS:000386333100002
Contributors: Ueki, Kohjiro; Sasako, Takayoshi; Kato, Masayuki; Okazaki, Yukiko; Okahata, Sumie; Katsuyama, Hisayuki; Haraguchi, Mikiko; Morita, Ai; Ohashi, Ken; Hara, Kazuo et al.
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Differential hepatic distribution of insulin receptor substrates causes selective insulin resistance in diabetes and obesity

Nature Communications
2016 | Journal article
DOI: 10.1038/NCOMMS12977
WOSUID: WOS:000385554600001
Contributors: Kubota, Naoto; Kubota, Tetsuya; Kajiwara, Eiji; Iwamura, Tomokatsu; Kumagai, Hiroki; Watanabe, Taku; Inoue, Mariko; Takamoto, Iseki; Sasako, Takayoshi; Kumagai, Katsuyoshi et al.
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Adiponectin Enhances Insulin Sensitivity by Increasing Hepatic IRS-2 Expression via a Macrophage-Derived IL-6-Dependent Pathway

Cell Metabolism
2011 | Journal article
DOI: 10.1016/J.CMET.2011.02.010
WOSUID: WOS:000289381300011
Contributors: Awazawa, Motoharu; Ueki, Kohjiro; Inabe, Kazunori; Yamauchi, Toshimasa; Kubota, Naoto; Kaneko, Kazuma; Kobayashi, Masatoshi; Iwane, Aya; Sasako, Takayoshi; Okazaki, Yukiko et al.
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Blockade of class IB phosphoinositide-3 kinase ameliorates obesity-induced inflammation and insulin resistance

Proceedings of the National Academy of Sciences
2011 | Journal article
DOI: 10.1073/PNAS.1016430108
WOSUID: WOS:000289265300052
Contributors: Kobayashi, Naoki; Ueki, Kohjiro; Okazaki, Yukiko; Iwane, Aya; Kubota, Naoto; Ohsugi, Mitsuru; Awazawa, Motoharu; Kobayashi, Masatoshi; Sasako, Takayoshi; Kaneko, Kazuma et al.
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Generation of Transgenic Mice on an NOD/SCID Background Using the Conventional Microinjection Technique

Biology of Reproduction
2011 | Journal article
DOI: 10.1095/BIOLREPROD.110.087106
WOSUID: WOS:000288596900009
Contributors: Kumagai, Katsuyoshi; Kubota, Naoto; Saito, Toshiki I.; Sasako, Takayoshi; Takizawa, Rumi; Sudo, Katsuko; Kurokawa, Mineo; Kadowaki, Takashi
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Impaired Insulin Signaling in Endothelial Cells Reduces Insulin-Induced Glucose Uptake by Skeletal Muscle

Cell Metabolism
2011 | Journal article
DOI: 10.1016/J.CMET.2011.01.018
WOSUID: WOS:000288150200010
Contributors: Kubota, Tetsuya; Kubota, Naoto; Kumagai, Hiroki; Yamaguchi, Shinichi; Kozono, Hideki; Takahashi, Takehiro; Inoue, Mariko; Itoh, Shinsuke; Takamoto, Iseki; Sasako, Takayoshi et al.
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Dynamic functional relay between insulin receptor substrate 1 and 2 in hepatic insulin signaling during fasting and feeding

Cell Metabolism
2008 | Journal article
DOI: 10.1016/J.CMET.2008.05.007
WOSUID: WOS:000257339600009
Contributors: Kubota, Naoto; Kubota, Tetsuya; Itoh, Shinsuke; Kumagai, Hiroki; Kozono, Hideki; Takamoto, Iseki; Mineyama, Tomoka; Ogata, Hitomi; Tokuyama, Kumpei; Ohsugi, Mitsuru et al.
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Peer review (47 reviews for 12 publications/grants)

Review activity for Acta diabetologica. (4)
Review activity for Acta diabetologica. (1)
Review activity for Advances in therapy. (6)
Review activity for Advances in therapy. (1)
Review activity for Cellular and molecular life sciences (1)
Review activity for Diabetes Therapy (13)
Review activity for Diabetes therapy. (3)
Review activity for Diabetic medicine. (1)
Review activity for Gene. (2)
Review activity for Heliyon. (2)
Review activity for Journal of cachexia, sarcopenia and muscle. (7)
Review activity for Journal of diabetes investigation. (6)
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