Personal information

United States

Activities

Employment (6)

University of Arizona: Tucson, AZ, US

2019 to present | Research Scientist (Immunobiology)
Employment
Source: Self-asserted source
Jennifer L Uhrlaub

University of Arizona: Tucson, AZ, US

2017 to 2019 | Associate Research Scientist (Immunobiology)
Employment
Source: Self-asserted source
Jennifer L Uhrlaub

The University of Arizona: Tucson, AZ, US

2008 to 2017 | Research Associate (Immunobiology)
Employment
Source: Self-asserted source
Jennifer L Uhrlaub

Oregon Health and Science University: Portland, OR, US

2006 to 2008 | Research Associate
Employment
Source: Self-asserted source
Jennifer L Uhrlaub

Sidney Kimmel Cancer Center: San Diego, CA, US

2004 to 2006 | Research Associate
Employment
Source: Self-asserted source
Jennifer L Uhrlaub

Johns Hopkins University: Baltimore, MD, US

2000 to 2003 | Research Technician
Employment
Source: Self-asserted source
Jennifer L Uhrlaub

Education and qualifications (3)

University of Arizona: Tucson, Arizona, US

2023-08-01 to 2026-05-20 | PhD - Molecular Medicine (Immunobiology)
Education
Source: Self-asserted source
Jennifer L Uhrlaub

Johns Hopkins University: Baltimore, MD, US

2010-05 | MS Biotechnology
Education
Source: Self-asserted source
Jennifer L Uhrlaub

McDaniel College: Westminster, MD, US

1996-09-01 to 2000-05-15 | BA in Biochemistry
Education
Source: Self-asserted source
Jennifer L Uhrlaub

Works (48)

Risk reduction in SARS-CoV-2 infection and reinfection conferred by humoral antibody levels among essential workers during Omicron predominance

PLOS ONE
2024-12-31 | Journal article
Contributors: James Hollister; Maemu Petronella Gededzha; Cynthia Porter; Ryan Sprissler; Shawn C. Beitel; James K. Romine; Jennifer L. Uhrlaub; Lauren Grant; Young M. Yoo; Ashley Fowlkes et al.
Source: check_circle
Crossref

Evaluating Immunologic and Illness Outcomes of SARS-CoV-2 Infection in Vaccinated and Unvaccinated Children Aged ≥ 5 Years, in a Multisite Longitudinal Cohort

Diseases
2024-08-01 | Journal article
Contributors: Cynthia Porter; Zoe L. Lyski; Jennifer L. Uhrlaub; Katherine D. Ellingson; Zuha Jeddy; Lisa Gwynn; Patrick Rivers; Ryan Sprissler; Kurt T. Hegmann; Melissa M. Coughlin et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Risk reduction in SARS-CoV-2 infection and reinfection conferred by humoral antibody levels among essential workers during Omicron predominance

2024-06-30 | Preprint
Contributors: James Hollister; Cynthia Porter; Ryan Sprissler; Shawn C Beitel; James K. Romine; Jennifer L. Uhrlaub; Lauren Grant; Young M. Yoo; Ashley Fowlkes; Amadea Britton et al.
Source: check_circle
Crossref

Virological, innate, and adaptive immune profiles shaped by variation in route and age of host in murine cytomegalovirus infection.

Journal of virology
2024-04-15 | Journal article
Contributors: Christopher Coplen; Jergovic M; Terner EL; Bradshaw CM; Uhrlaub JL; Janko Z. Nikolich
Source: Self-asserted source
Jennifer L Uhrlaub

Anti-cytomegalovirus antibody levels stratify human immune profiles across the lifespan.

GeroScience
2024-03-21 | Journal article
Contributors: Watanabe M; Davidson L; Smith P; Castellucio PF; Jergovic M; Uhrlaub JL; Smithey MJ; Fantry LE; Dechambre B; Wilson RC et al.
Source: Self-asserted source
Jennifer L Uhrlaub

Hybrid immunity and SARS-CoV-2 antibodies: results of the HEROES-RECOVER prospective cohort study.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
2024-03-11 | Journal article
Contributors: James K. Romine; Li H; Melissa Coughlin; Jefferson Michael Jones; Amadea Britton; Harmony Tyner; Fuller SB; Bloodworth R; Edwards LJ; Etoule JN et al.
Source: Self-asserted source
Jennifer L Uhrlaub

ChronicToxoplasma gondiiinfection curtails the cytotoxic potential of acute T cell responses to West Nile virus in the brain

2024-01-23 | Preprint
Contributors: Jennifer L. Uhrlaub; Kathryn E. McGovern; Emily F. Merritt; Michael S. Kuhns; Anita A. Koshy; Janko Ž. Nikolich
Source: check_circle
Crossref

Author Correction: Infection-induced type I interferons critically modulate the homeostasis and function of CD8+ naïve T cells

Nature Communications
2024-01-11 | Journal article
Contributors: Mladen Jergović; Christopher P. Coplen; Jennifer L. Uhrlaub; David G. Besselsen; Shu Cheng; Megan J. Smithey; Janko Nikolich-Žugich
Source: check_circle
Crossref

Characterization of low copy number human angiotensin-converting enzyme 2 (hACE2)-transgenic mice as an improved model of SARS-CoV-2 infection

2023-09-01 | Preprint
Contributors: Christine M. Bradshaw; Teodora Georgieva; Trevor N. Tankersley; Tama Taylor-Doyle; Larry Johnson; Jennifer L. Uhrlaub; David Besselsen; Janko Ž. Nikolich
Source: check_circle
Crossref

Humoral Immune Response to Messenger RNA Coronavirus Disease 2019 Vaccination Among Children Aged 5–11 Years in a Multisite Prospective Cohort Study, September 2021–September 2022

Open Forum Infectious Diseases
2023-08-01 | Journal article
Contributors: Zoe L Lyski; Cynthia Porter; Jennifer L Uhrlaub; Katherine D Ellingson; Zuha Jeddy; Lisa Gwynn; Patrick Rivers; Ryan Sprissler; Kurt T Hegmann; Melissa Coughlin et al.
Source: check_circle
Crossref

Lifelong cytomegalovirus and early‐LIFE irradiation synergistically potentiate age‐related defects in response to vaccination and infection

Aging Cell
2022-07 | Journal article
Contributors: Jason L. Pugh; Christopher P. Coplen; Alona S. Sukhina; Jennifer L. Uhrlaub; Jose Padilla‐Torres; Tomonori Hayashi; Janko Nikolich‐Žugich
Source: check_circle
Crossref

Smartphone-based sensitive detection of SARS-CoV-2 from saline gargle samples via flow profile analysis on a paper microfluidic chip

Biosensors and Bioelectronics
2022-07 | Journal article
Contributors: Patarajarin Akarapipad; Kattika Kaarj; Lane E. Breshears; Katelyn Sosnowski; Jacob Baker; Brandon T. Nguyen; Ciara Eades; Jennifer L. Uhrlaub; Grace Quirk; Janko Nikolich-Žugich et al.
Source: check_circle
Crossref

Competent immune responses to SARS-CoV-2 variants in older adults following two doses of mRNA vaccination

Nature Communications
2022-05-24 | Journal article
Contributors: Mladen Jergović; Jennifer L. Uhrlaub; Makiko Watanabe; Christine M. Bradshaw; Lisa M. White; Bonnie J. LaFleur; Taylor Edwards; Ryan Sprissler; Michael Worobey; Deepta Bhattacharya et al.
Source: check_circle
Crossref

Quantitative restoration of immune defense in old animals determined by naive antigen‐specific CD8 T‐cell numbers

Aging Cell
2022-04 | Journal article
Contributors: Jennifer L. Uhrlaub; Mladen Jergović; Christine M. Bradshaw; Sandip Sonar; Christopher P. Coplen; Jarrod Dudakov; Kristy O. Murray; Marion C. Lanteri; Michael P. Busch; Marcel R. M. van den Brink et al.
Source: check_circle
Crossref

Early age–related atrophy of cutaneous lymph nodes precipitates an early functional decline in skin immunity in mice with aging

Proceedings of the National Academy of Sciences
2022-04-26 | Journal article
Contributors: Sandip Ashok Sonar; Jennifer L. Uhrlaub; Christopher P. Coplen; Gregory D. Sempowski; Jarrod A. Dudakov; Marcel R. M. van den Brink; Bonnie J. LaFleur; Mladen Jergović; Janko Nikolich-Žugich
Source: check_circle
Crossref

Sensitive, smartphone-based SARS-CoV-2 detection from clinical saline gargle samples

PNAS Nexus
2022-04-15 | Journal article
Contributors: Lane E Breshears; Brandon T Nguyen; Patarajarin Akarapipad; Katelyn Sosnowski; Kattika Kaarj; Grace Quirk; Jennifer L Uhrlaub; Janko Nikolich-Žugich; Michael Worobey; Jeong-Yeol Yoon et al.
Source: check_circle
Crossref

Direct capture and smartphone quantification of airborne SARS-CoV-2 on a paper microfluidic chip

Biosensors and Bioelectronics
2022-03 | Journal article
Contributors: Sangsik Kim; Patarajarin Akarapipad; Brandon T. Nguyen; Lane E. Breshears; Katelyn Sosnowski; Jacob Baker; Jennifer L. Uhrlaub; Janko Nikolich-Žugich; Jeong-Yeol Yoon
Source: check_circle
Crossref

Lifelong Cytomegalovirus and Early-Life Irradiation Synergistically Potentiate Age-Related Defects in Response to Vaccination and Infection

2021-12-03 | Other
Contributors: Jason L. Pugh; Christopher P. Coplen; Alona S. Sukhina; Jennifer L. Uhrlaub; Jose Padilla-Torres; Tomonori Hayashi; Janko Nikolich-Zugich
Source: check_circle
Crossref

The impact of murine cytomegalovirus (mCMV) route and age at infection upon virus spread, immune responses and the establishment of latency

2021-12-01 | Other
Contributors: Christopher P. Coplen; Mladen Jergovic; Elana L. Terner; Jennifer L. Uhrlaub; Janko Nikolich-Žugich
Source: check_circle
Crossref

Infection-induced type I interferons critically modulate the homeostasis and function of CD8+ naïve T cells

Nature Communications
2021-09-06 | Journal article
Contributors: Mladen Jergović; Christopher P. Coplen; Jennifer L. Uhrlaub; David G. Besselsen; Shu Cheng; Megan J. Smithey; Janko Nikolich-Žugich
Source: check_circle
Crossref

Quantitative Restoration of Immune Defense in Old Animals Determined by Naïve Antigen-Specific CD8 T cell Numbers

2021-08-10 | Preprint
Contributors: Jennifer L. Uhrlaub; Mladen Jergović; Christine M. Bradshaw; Sandip Sonar; Christopher P. Coplen; Jarrod Dudakov; Kristy O. Murray; Marion C. Lanteri; Michael P. Busch; Marcel R. M. van den Brink et al.
Source: check_circle
Crossref

Competent immune responses to SARS-CoV-2 variants in older adults following mRNA vaccination

2021-07-22 | Preprint
Contributors: Mladen Jergović; Jennifer L. Uhrlaub; Makiko Watanabe; Christine M. Bradshaw; Lisa M. White; Bonnie J. LaFleur; Taylor Edwards; Ryan Sprissler; Michael Worobey; Deepta Bhattacharya et al.
Source: check_circle
Crossref

Affinity-Restricted Memory B Cells Dominate Recall Responses to Heterologous Flaviviruses

Immunity
2020-11 | Journal article
Contributors: Rachel Wong; Julia A. Belk; Jennifer Govero; Jennifer L. Uhrlaub; Dakota Reinartz; Haiyan Zhao; John M. Errico; Lucas D’Souza; Tyler J. Ripperger; Janko Nikolich-Zugich et al.
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Crossref

MAVS regulates the quality of the antibody response to West-Nile Virus

PLOS Pathogens
2020-10-26 | Journal article
Contributors: Marvin O’Ketch; Sonja Best; Spencer Williams; Cameron Larson; Jennifer L. Uhrlaub; Rachel Wong; Brenna Hall; Neha R. Deshpande; Dominik Schenten
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Crossref

Lymph nodes as barriers to T-cell rejuvenation in aging mice and nonhuman primates

Aging Cell
2018-11 | Journal article
Part of ISSN: 1474-9718
Contributors: Heather L. Thompson; Megan J. Smithey; Jennifer L. Uhrlaub; Ilija Jeftić; Mladen Jergović; Sarah E. White; Noreen Currier; Anna M. Lang; Afam Okoye; Byung Park et al.
Source: Self-asserted source
Jennifer L Uhrlaub via Crossref Metadata Search

Abstract 020: Sex Difference in T Regulatory Cells After Adoptive Transfer From Hypertensive Donors Leads to Protection Against T Cell-Mediated Hypertension in Premenopausal Female Mice

Hypertension
2018-09 | Journal article
Part of ISSN: 0194-911X
Contributors: Dennis P Pollow; Megan A Sylvester; Nathaniel A Husband; Joshua A Uhlorn; Jill Romero-Aleshire; Jennifer Uhrlaub; Janko Nikolich-Zugich; Heddwen L Brooks
Source: Self-asserted source
Jennifer L Uhrlaub via Crossref Metadata Search

A disconnect between precursor frequency, expansion potential, and site-specific CD4+ T cell responses in aged mice

PLOS ONE
2018-06-04 | Journal article
Part of ISSN: 1932-6203
Contributors: Neha R. Deshpande; Jennifer L. Uhrlaub; Sing Sing Way; Janko Nikolich-Žugich; Michael S. Kuhns; Steven M. Varga
Source: Self-asserted source
Jennifer L Uhrlaub via Crossref Metadata Search

Cutting Edge: The Aging Immune System Reveals the Biological Impact of Direct Antigen Presentation on CD8 T Cell Responses

The Journal of Immunology
2017-07-15 | Journal article
Contributors: Jennifer L. Uhrlaub; Megan J. Smithey; Janko Nikolich-Žugich
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Crossref

Dysregulated TGF-β Production Underlies the Age-Related Vulnerability to Chikungunya Virus

PLOS Pathogens
2016-10 | Journal article
Contributors: Jennifer L. Uhrlaub; Vesna Pulko; Victor R. DeFilippis; Rebecca Broeckel; Daniel N. Streblow; Gary D. Coleman; Byung S. Park; John F. Lindo; Ivan Vickers; Joshua J. Anzinger et al.
Source: Self-asserted source
Jennifer L Uhrlaub via Crossref Metadata Search

Acute systemic DNA damage in youth does not impair immune defense with aging

Aging Cell
2016-04 | Journal article
Contributors: Jason L. Pugh; Sarah A. Foster; Alona S. Sukhina; Janka Petravic; Jennifer L. Uhrlaub; Jose Padilla-Torres; Tomonori Hayashi; Kei Nakachi; Megan J. Smithey; Janko Nikolich-Žugich
Source: Self-asserted source
Jennifer L Uhrlaub via Crossref Metadata Search

Immune Protection against Virus Challenge in Aging Mice Is Not Affected by Latent Herpesviral Infections

Journal of Virology
2015-09-02 | Journal article
Contributors: Thomas F. Marandu; Jennifer D. Oduro; Lisa Borkner; Iryna Dekhtiarenko; Jennifer L. Uhrlaub; Anja Drabig; Andrea Kröger; Janko Nikolich-Zugich; Luka Cicin-Sain; K. Frueh
Source: Self-asserted source
Jennifer L Uhrlaub via Crossref Metadata Search

Lifespan-extending caloric restriction or mTOR inhibition impair adaptive immunity of old mice by distinct mechanisms

Aging Cell
2014-11 | Journal article
Contributors: Emily L. Goldberg; Melissa J. Romero-Aleshire; Kristin R. Renkema; Melissa S. Ventevogel; Wade M. Chew; Jennifer L. Uhrlaub; Megan J. Smithey; Kirsten H. Limesand; Gregory D. Sempowski; Heddwen L. Brooks et al.
Source: Self-asserted source
Jennifer L Uhrlaub via Crossref Metadata Search

Lost in translation: mice, men and cutaneous immunity in old age

Biogerontology
2014-07 | Journal article
Contributors: Megan J. Smithey; Jennifer L. Uhrlaub; Gang Li; Milica Vukmanovic-Stejic; Arne N. Akbar; Janko Nikolich-Zugich
Source: Self-asserted source
Jennifer L Uhrlaub via Crossref Metadata Search

Immune Memory–Boosting Dose of Rapamycin Impairs Macrophage Vesicle Acidification and Curtails Glycolysis in Effector CD8 Cells, Impairing Defense against Acute Infections

The Journal of Immunology
2014-06-09 | Journal article
Contributors: Emily L. Goldberg; Megan J. Smithey; Lydia K. Lutes; Jennifer L. Uhrlaub; Janko Nikolich-Žugich
Source: Self-asserted source
Jennifer L Uhrlaub via Crossref Metadata Search

Sex Differences in T-Lymphocyte Tissue Infiltration and Development of Angiotensin II Hypertension

Hypertension
2014-06-02 | Journal article
Contributors: D. P. Pollow; J. Uhrlaub; M. J. Romero-Aleshire; K. Sandberg; J. Nikolich-Zugich; H. L. Brooks; M. Hay
Source: Self-asserted source
Jennifer L Uhrlaub via Crossref Metadata Search

Aging and Cytomegalovirus Infection Differentially and Jointly Affect Distinct Circulating T Cell Subsets in Humans

The Journal of Immunology
2014-02-05 | Journal article
Contributors: A. M. Wertheimer; M. S. Bennett; B. Park; J. L. Uhrlaub; C. Martinez; V. Pulko; N. L. Currier; D. Nikolich-Zugich; J. Kaye; J. Nikolich-Zugich
Source: Self-asserted source
Jennifer L Uhrlaub via Crossref Metadata Search

Age-related changes in CD8 T cell homeostasis and immunity to infection

Seminars in Immunology
2012-10 | Journal article
Contributors: Janko Nikolich-Žugich; Gang Li; Jennifer L. Uhrlaub; Kristin R. Renkema; Megan J. Smithey
Source: Self-asserted source
Jennifer L Uhrlaub via Crossref Metadata Search

Cytomegalovirus Infection Impairs Immune Responses and Accentuates T-cell Pool Changes Observed in Mice with Aging

PLoS Pathogens
2012-08 | Journal article
Contributors: Luka Cicin-Sain; James D. Brien; Jennifer L. Uhrlaub; Anja Drabig; Thomas F. Marandu; Janko Nikolich-Zugich; Karen L. Mossman
Source: Self-asserted source
Jennifer L Uhrlaub via Crossref Metadata Search

Induction of the Cellular MicroRNA, Hs_154, by West Nile Virus Contributes to Virus-Mediated Apoptosis through Repression of Antiapoptotic Factors

Journal of Virology
2012-02 | Journal article
Contributors: J. L. Smith; F. E. Grey; J. L. Uhrlaub; J. Nikolich-Zugich; A. J. Hirsch
Source: Self-asserted source
Jennifer L Uhrlaub via Crossref Metadata Search

Repeated In Vivo Stimulation of T and B Cell Responses in Old Mice Generates Protective Immunity against Lethal West Nile Virus Encephalitis

The Journal of Immunology
2011-02 | Journal article
Contributors: J. L. Uhrlaub; J. D. Brien; D. G. Widman; P. W. Mason; J. Nikolich-Zugich
Source: Self-asserted source
Jennifer L Uhrlaub via Crossref Metadata Search

Immune Response to the West Nile Virus in Aged Non-Human Primates

PLoS ONE
2010 | Journal article
Contributors: Anne M. Wertheimer; Jennifer L. Uhrlaub; Alec Hirsch; Guruprasad Medigeshi; Jerald Sprague; Alfred Legasse; Jennifer Wilk; Clayton A. Wiley; Peter Didier; Robert B. Tesh et al.
Source: Self-asserted source
Jennifer L Uhrlaub via Crossref Metadata Search

Key role of T cell defects in age-related vulnerability to West Nile virus

The Journal of Experimental Medicine
2009-11-09 | Journal article
Contributors: James D. Brien; Jennifer L. Uhrlaub; Alec Hirsch; Clayton A. Wiley; Janko Nikolich-Žugich
Source: Self-asserted source
Jennifer L Uhrlaub via Crossref Metadata Search

West Nile Virus Capsid Degradation of Claudin Proteins Disrupts Epithelial Barrier Function

Journal of Virology
2009-04 | Journal article
Contributors: G. R. Medigeshi; A. J. Hirsch; J. D. Brien; J. L. Uhrlaub; P. W. Mason; C. Wiley; J. Nikolich-Zugich; J. A. Nelson
Source: Self-asserted source
Jennifer L Uhrlaub via Crossref Metadata Search

West Nile Virus-Specific CD4 T Cells Exhibit Direct Antiviral Cytokine Secretion and Cytotoxicity and Are Sufficient for Antiviral Protection

The Journal of Immunology
2008 | Journal article
Contributors: J. D. Brien; J. L. Uhrlaub; J. Nikolich-Zugich
Source: Self-asserted source
Jennifer L Uhrlaub via Crossref Metadata Search

Protective capacity and epitope specificity of CD8+ T cells responding to lethal West Nile virus infection

European Journal of Immunology
2007-06-11 | Journal article
Contributors: James D. Brien; Jennifer L. Uhrlaub; Janko Nikolich-Žugich
Source: Self-asserted source
Jennifer L Uhrlaub via Crossref Metadata Search

Neuroprotective and Anti–Human Immunodeficiency Virus Activity of Minocycline

JAMA
2005-04 | Journal article
Contributors: M. Christine Zink
Source: Self-asserted source
Jennifer L Uhrlaub via Crossref Metadata Search

Dysregulation of Mitogen-Activated Protein Kinase Signaling Pathways in Simian Immunodeficiency Virus Encephalitis

The American Journal of Pathology
2004-02 | Journal article
Contributors: Sheila A. Barber; Jennifer L. Uhrlaub; Jesse B. DeWitt; Patrick M. Tarwater; M. Christine Zink
Source: Self-asserted source
Jennifer L Uhrlaub via Crossref Metadata Search

Expression of Simian Immunodeficiency Virus (SIV) Nef in Astrocytes during Acute and Terminal Infection and Requirement of Nef for Optimal Replication of Neurovirulent SIV In Vitro

Journal of Virology
2003-06 | Journal article
Contributors: E. D. Overholser; G. D. Coleman; J. L. Bennett; R. J. Casaday; M. C. Zink; S. A. Barber; J. E. Clements
Source: Self-asserted source
Jennifer L Uhrlaub via Crossref Metadata Search

Peer review (1 review for 1 publication/grant)

Review activity for BMC medicine (1)