Personal information

Emails & domains

Verified email domains

Activities

Collapse all

Employment (6)

National Institutes of Health: Bethesda, MD, US

2023-05 to present | Associate Scientist (NIDDK)
Employment
Source: Self-asserted source
HYE KYUNG LEE

National Institutes of Health: Bethesda, Maryland, US

2020-12-06 to 2023-05 | Staff scientist (NIDDK)
Employment
Source: Self-asserted source
HYE KYUNG LEE

National Institutes of Health: Bethesda, MD, US

2015-12-14 to 2020-12-05 | Postdoc (NIDDK)
Employment
Source: Self-asserted source
HYE KYUNG LEE

Seoul National University: Gwanak-gu, Seoul, KR

2009-12-01 to 2011-08-31 | Research Scientist (Oral Histology-Developmental Biology & Dental Research)
Employment
Source: Self-asserted source
HYE KYUNG LEE

Yonsei University: Seodaemun-gu, Seoul, KR

2008-02-01 to 2009-11-31 | Research Scientist (Bioscience)
Employment
Source: Self-asserted source
HYE KYUNG LEE

Sejong University: Gwangjin-gu, Seoul, KR

2005-03-01 to 2008-01-31 | Research Scientist (Bioscience and Biotechnology)
Employment
Source: Self-asserted source
HYE KYUNG LEE

Education and qualifications (3)

Seoul National University: Gwanak-gu, Seoul, KR

2011-09-01 to 2015-08-31 | PhD (Bioscience and Biotechnology)
Education
Source: Self-asserted source
HYE KYUNG LEE

Sejong University: Gwangjin-gu, Seoul, KR

2003-03-01 to 2005-02-28 | MS (Bioscience and Biotechnology)
Education
Source: Self-asserted source
HYE KYUNG LEE

Sejong University: Gwangjin-gu, Seoul, KR

1999-03-01 to 2003-02-28 | BS (Oral Histology-Developmental Biology & Dental Research)
Education
Source: Self-asserted source
HYE KYUNG LEE

Funding (1)

Korea Visiting Scientist Training Award

2015-12 to 2017-11 | Award
Korea Health Industry Development Institute (Seoul, KR)
Source: Self-asserted source
HYE KYUNG LEE

Works (50 of 77)

Items per page:
Page 1 of 2

Y665F variant of mouseStat5bprotects against acute kidney injury through transcriptomic shifts in renal gene expression

2025-02-23 | Preprint
DOI: 10.1101/2025.02.19.639141
Contributors: Jakub Jankowski; Hye Kyung Lee; Lothar Hennighausen
Source: check_circle
Crossref

STAT5B leukemic mutations, altering SH2 tyrosine 665, have opposing impacts on immune gene programs

2024-12-22 | Preprint
DOI: 10.1101/2024.12.20.629685
Contributors: Hye Kyung Lee; Jichun Chen; Rachael L. Philips; Sung-Gwon Lee; Xingmin Feng; Zhijie Wu; Chengyu Liu; Aaron B. Schultz; Molly Dalzell; Foster Birnbaum et al.
Source: check_circle
Crossref

RNA sequencing depth guidelines for the study of alternative splicing

2024-10-13 | Preprint
DOI: 10.1101/2024.10.09.617406
Contributors: Olga Tsoy; Sabine Ameling; Sören Franzenburg; Markus Hoffmann; Lina Liv-Willuth; Hye Kyung Lee; Ludwig Knabl; Priscilla A. Furth; Uwe Völker; Lothar Hennighausen et al.
Source: check_circle
Crossref

Sexually dimorphic renal expression of mouse Klotho is directed by a kidney-specific distal enhancer responsive to HNF1b

Communications Biology
2024-09-14 | Journal article
DOI: 10.1038/s42003-024-06855-6
Contributors: Jakub Jankowski; Hye Kyung Lee; Chengyu Liu; Julia Wilflingseder; Lothar Hennighausen
Source: check_circle
Crossref

STAT5B SH2 variants disrupt mammary enhancers and the stability of genetic programs during pregnancy

2024-05-09 | Preprint
DOI: 10.1101/2024.05.06.592736
Contributors: Hye Kyung Lee; Chengyu Liu; Lothar Hennighausen
Source: check_circle
Crossref

Sexually dimorphic renal expression of Klotho is directed by a kidney-specific distal enhancer responsive to HNF1b

2024-04-22 | Preprint
DOI: 10.21203/rs.3.rs-4188774/v1
Contributors: Jakub Jankowski; Hye Kyung Lee; Chengyu Liu; Julia Wilflingseder; Lothar Hennighausen
Source: check_circle
Crossref

Machine Learning to Identify Critical Biomarker Profiles in New SARS-CoV-2 Variants

Microorganisms
2024-04-15 | Journal article
DOI: 10.3390/microorganisms12040798
Contributors: Christoph Schatz; Ludwig Knabl; Hye Kyung Lee; Rita Seeboeck; Dorothee von Laer; Eliott Lafon; Wegene Borena; Harald Mangge; Florian Prüller; Adelina Qerimi et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Variant- and vaccination-specific alternative splicing profiles in SARS-CoV-2 infections

iScience
2024-03 | Journal article
DOI: 10.1016/j.isci.2024.109177
Contributors: Sung-Gwon Lee; Priscilla A. Furth; Lothar Hennighausen; Hye Kyung Lee
Source: check_circle
Crossref

Sexually dimorphic renal expression ofKlothois directed by a kidney-specific distal enhancer responsive to HNF1b

2024-03-04 | Preprint
DOI: 10.1101/2024.02.29.582831
Contributors: Jakub Jankowski; Hye Kyung Lee; Chengyu Liu; Julia Wilflingseder; Lothar Hennighausen
Source: check_circle
Crossref

Insights into SARS-CoV-2 Immune Responses, Disease Severity, and Optimal Sequencing Depth

2023 | Conference paper
DOI: 10.14293/GOF.23.43
Contributors: Markus Hoffmann; Lina-Liv Willruth; Alexander Dietrich; Hye Kyung Lee; Ludwig Knabl; Nico Trummer; Jakub Jankowski; Jan Baumbach; Priscilla Furth; Lothar Hennighausen et al.
Source: check_circle
Crossref

Multi-omics analysis of microbiome ‘Kimchi” in cancer research

2023 | Conference paper
DOI: 10.14293/GOF.23.07
Contributors: Woo Kyun Bae; Hye Kyung Lee; Misun Yun; Lothar Hennighausen
Source: check_circle
Crossref

Supporting data for "TF-Prioritizer: a java pipeline to prioritize condition-specific transcription factors"

GigaScience Database
2023 | Dataset
DOI: 10.5524/102379
Contributors: Markus Hoffmann; Nico Trummer; Leon Schwartz; Jankowski Jakub; HYE KYUNG LEE; Lina-Liv Willruth; Olga Lazareva; Kevin Yuan; Nina Baumgarten; Florian Schmidt et al.
Source: check_circle
DataCite

TF-Prioritizer: a Java pipeline to prioritize condition-specific transcription factors

2023 | Conference paper
DOI: 10.14293/GOF.23.44
Contributors: Markus Hoffmann; Nico Trummer; Leon Schwartz; Jakub Jankowski; Hye Kyung Lee; Lina-Liv Willruth; Olga Lazareva; Kevin Yuan; Nina Baumgarten; Florian Schmidt et al.
Source: check_circle
Crossref

Understanding human disease mutations through gene editing and genome-wide next generation investigations

2023 | Conference paper
DOI: 10.14293/GOF.23.10
Contributors: Hye-Kyung Lee; Lothar Hennighausen
Source: check_circle
Crossref

Variant- and Vaccination-Specific Alternative Splicing Profiles in SARS-CoV-2 Infections

2023-11-27 | Preprint
DOI: 10.1101/2023.11.24.568603
Contributors: Sung-Gwon Lee; Priscilla A. Furth; Lothar Hennighausen; Hye Kyung Lee
Source: check_circle
Crossref

Blood transcriptomics analysis offers insights into variant-specific immune response to SARS-CoV-2

2023-11-06 | Preprint
DOI: 10.1101/2023.11.03.564190
Contributors: Markus Hoffmann; Lina-Liv Willruth; Alexander Dietrich; Hye Kyung Lee; Ludwig Knabl; Nico Trummer; Jan Baumbach; Priscilla A. Furth; Lothar Hennighausen; Markus List
Source: check_circle
Crossref

Cell-specific and shared regulatory elements control a multigene locus active in mammary and salivary glands

Nature Communications
2023-08-17 | Journal article
DOI: 10.1038/s41467-023-40712-0
Contributors: Hye Kyung Lee; Michaela Willi; Chengyu Liu; Lothar Hennighausen
Source: check_circle
Crossref

Analysis of immune responses in patients with CLL after heterologous COVID-19 vaccination

Blood Advances
2023-05-23 | Journal article
DOI: 10.1182/bloodadvances.2022008445
Contributors: Hye Kyung Lee; Manuela A. Hoechstetter; Maike Buchner; Trang Thu Pham; Jin Won Huh; Katharina Müller; Sabine Zange; Heiner von Buttlar; Philipp Girl; Roman Wölfel et al.
Source: check_circle
Crossref

A cytokine-responsive promoter is required for distal enhancer function mediating the hundreds-fold increase in milk protein gene expression during lactation

2023-02-07 | Preprint
DOI: 10.21203/rs.3.rs-2533546/v1
Contributors: Lothar Hennighausen; Hye Kyung Lee; Chengyu Liu
Source: check_circle
Crossref

Cell-specific and shared enhancers control a high-density multi-gene locus active in mammary and salivary glands

2023-02-07 | Preprint
DOI: 10.1101/2023.02.06.527373
Contributors: Hye Kyung Lee; Michaela Willi; Chengyu Liu; Lothar Hennighausen
Source: check_circle
Crossref

Cell-specific and shared enhancers control a high-density multi-gene locus active in mammary and salivary glands

2023-02-07 | Preprint
DOI: 10.21203/rs.3.rs-2533579/v1
Contributors: Lothar Hennighausen; Hye Kyung Lee; Michaela Willi; Chengyu Liu
Source: check_circle
Crossref

A cytokine-responsive promoter is required for distal enhancer function mediating the hundreds-fold increase in milk protein gene expression during lactation

2023-02-06 | Preprint
DOI: 10.1101/2023.02.06.527375
Contributors: Hye Kyung Lee; Chengyu Liu; Lothar Hennighausen
Source: check_circle
Crossref

circRNA-sponging: a pipeline for extensive analysis of circRNA expression and their role in miRNA sponging

2023-01-20 | Preprint
DOI: 10.1101/2023.01.19.524495
Contributors: Markus Hoffmann; Leon Schwartz; Octavia-Andreea Ciora; Nico Trummer; Lina-Liv Willruth; Jakub Jankowski; Hye Kyung Lee; Jan Baumbach; Priscilla Furth; Lothar Hennighausen et al.
Source: check_circle
Crossref

circRNA-sponging: a pipeline for extensive analysis of circRNA expression and their role in miRNA sponging

Bioinformatics Advances
2023-01-05 | Journal article
DOI: 10.1093/bioadv/vbad093
Contributors: Markus Hoffmann; Leon Schwartz; Octavia-Andreea Ciora; Nico Trummer; Lina-Liv Willruth; Jakub Jankowski; Hye Kyung Lee; Jan Baumbach; Priscilla A Furth; Lothar Hennighausen et al.
Source: check_circle
Crossref

TF-Prioritizer: a Java pipeline to prioritize condition-specific transcription factors

GigaScience
2022-12-28 | Journal article
DOI: 10.1093/gigascience/giad026
Contributors: Markus Hoffmann; Nico Trummer; Leon Schwartz; Jakub Jankowski; Hye Kyung Lee; Lina-Liv Willruth; Olga Lazareva; Kevin Yuan; Nina Baumgarten; Florian Schmidt et al.
Source: check_circle
Crossref

TF-Prioritizer: a java pipeline to prioritize condition-specific transcription factors

2022-10-21 | Preprint
DOI: 10.1101/2022.10.19.512881
Contributors: Markus Hoffmann; Nico Trummer; Leon Schwartz; Jakub Jankowski; Hye Kyung Lee; Lina-Liv Willruth; Olga Lazareva; Kevin Yuan; Nina Baumgarten; Florian Schmidt et al.
Source: check_circle
Crossref

Comprehensive analysis of immune responses in CLL patients after heterologous COVID-19 vaccination

2022-09-21 | Preprint
DOI: 10.1101/2022.09.21.22280205
Contributors: Hye Kyung Lee; Manuela A. Hoechstetter; Maike Buchner; Trang Thu Pham; Jin Won Huh; Katharina Müller; Sabine Zange; Heiner von Buttlar; Philipp Girl; Roman Wölfel et al.
Source: check_circle
Crossref

Prior Vaccination Exceeds Prior Infection in Eliciting Innate and Humoral Immune Responses in Omicron Infected Outpatients.

Frontiers in immunology
2022-06-15 | Journal article
DOI: 10.3389/fimmu.2022.916686
PMID: 35784346
PMC: PMC9240221
Contributors: HYE KYUNG LEE
Source: Self-asserted source
HYE KYUNG LEE

Heterologous ChAdOx1-BNT162b2 vaccination in Korean cohort induces robust immune and antibody responses that includes Omicron.

iScience
2022-05-26 | Journal article
DOI: 10.1016/j.isci.2022.104473
PMID: 35637788
PMC: PMC9132682
Contributors: HYE KYUNG LEE
Source: Self-asserted source
HYE KYUNG LEE

Immune transcriptome and antibody response in adult-onset Still's disease with mild flare following administration of mRNA vaccine BNT162b2.

Rheumatology (Oxford, England)
2022-05-09 | Journal article
DOI: 10.1093/rheumatology/keac281
PMID: 35532082
Contributors: HYE KYUNG LEE
Source: Self-asserted source
HYE KYUNG LEE

Limited cross-variant immune response from SARS-CoV-2 Omicron BA.2 in naïve but not previously infected outpatients

2022-04-10 | Preprint
DOI: 10.1101/2022.04.07.22273565
Contributors: Hye Kyung Lee; Ludwig Knabl; Mary Walter; Priscilla A. Furth; Lothar Hennighausen
Source: check_circle
Crossref

Differences in transcriptional response underlie why prior vaccination exceeds prior infection in eliciting robust immune responses in Omicron infected outpatients

2022-03-30 | Preprint
DOI: 10.1101/2022.03.24.22272837
Contributors: Hye Kyung Lee; Ludwig Knabl; Mary Walter; Ludwig Knabl, Sr.; Yuhai Dai; Magdalena Füßl; Yasemin Caf; Claudia Jeller; Philipp Knabl; Martina Obermoser et al.
Source: check_circle
Crossref

mRNA vaccination in octogenarians 15 and 20 months after recovery from COVID-19 elicits robust immune and antibody responses that include Omicron.

Cell reports
2022-03-25 | Journal article
DOI: 10.1016/j.celrep.2022.110680
PMID: 35395191
PMC: PMC8947943
Contributors: HYE KYUNG LEE
Source: Self-asserted source
HYE KYUNG LEE

Tubular dentin formation by TGF-β/BMP signaling in dental epithelial cells.

Oral diseases
2022-02-24 | Journal article
DOI: 10.1111/odi.14170
PMID: 35199415
Contributors: HYE KYUNG LEE
Source: Self-asserted source
HYE KYUNG LEE

BNT162b2 vaccination enhances interferon-JAK-STAT-regulated antiviral programs in COVID-19 patients infected with the SARS-CoV-2 Beta variant.

Communications medicine
2022-02-22 | Journal article
DOI: 10.1038/s43856-022-00083-x
PMID: 35465056
PMC: PMC9029844
Contributors: HYE KYUNG LEE
Source: Self-asserted source
HYE KYUNG LEE

Immune transcriptome analysis of COVID-19 patients infected with SARS-CoV-2 variants carrying the E484K escape mutation identifies a distinct gene module.

Scientific reports
2022-02-18 | Journal article
DOI: 10.1038/s41598-022-06752-0
PMID: 35181735
PMC: PMC8857234
Contributors: HYE KYUNG LEE
Source: Self-asserted source
HYE KYUNG LEE

Genetic immune response and antibody repertoire of heterologous ChAdOx1-BNT162b2 vaccination in a Korean cohort

2022-02-08 | Preprint
DOI: 10.1101/2022.02.07.22270617
Contributors: Hye Kyung Lee; Jinyoung Go; Heungsup Sung; Seong Who Kim; Mary Walter; Ludwig Knabl; Priscilla Furth; Lothar Hennighausen; Jin Won Huh
Source: check_circle
Crossref

Robust immune response to the BNT162b mRNA vaccine in an elderly population vaccinated 15 months after recovery from COVID-19

2021-09-12 | Other
DOI: 10.1101/2021.09.08.21263284
Contributors: Hye Kyung Lee; Ludwig Knabl; Ludwig Knabl, Sr.; Sebastian Kapferer; Birgit Pateter; Mary Walter; Priscilla A. Furth; Lothar Hennighausen
Source: check_circle
Crossref

JAK inhibitors dampen activation of interferon-stimulated transcription of ACE2 isoforms in human airway epithelial cells.

Communications biology
2021-06-02 | Journal article
DOI: 10.1038/s42003-021-02167-1
PMID: 34079039
PMC: PMC8172581
Contributors: HYE KYUNG LEE
Source: Self-asserted source
HYE KYUNG LEE
grade
Preferred source (of 2)‎

Immune transcriptomes from hospitalized patients infected with the SARS-CoV-2 variants B.1.1.7 and B.1.1.7 carrying the E484K escape mutation

2021-05-30 | Other
DOI: 10.1101/2021.05.27.21257952
Contributors: Hye Kyung Lee; Ludwig Knabl; Ludwig Knabl, Sr.; Manuel Wieser; Anna Mur; August Zabernigg; Jana Schumacher; Norbert Kaiser; Priscilla A. Furth; Lothar Hennighausen
Source: check_circle
Crossref

Impact of BNT162b first vaccination on the immune transcriptome of elderly patients infected with the B.1.351 SARS-CoV-2 variant

2021-05-14 | Other
DOI: 10.1101/2021.05.11.21256862
Contributors: Ludwig Knabl; Hye Kyung Lee; Manuel Wieser; Anna Mur; August Zabernigg; Ludwig Knabl, Sr.; Simon Rauch; Matthias Bock; Jana Schumacher; Norbert Kaiser et al.
Source: check_circle
Crossref

Redundant and non-redundant cytokine-activated enhancers control Csn1s2b expression in the lactating mouse mammary gland

Nature Communications
2021-04-14 | Journal article
DOI: 10.1038/s41467-021-22500-w
Contributors: Hye Kyung Lee; Michaela Willi; Tyler Kuhns; Chengyu Liu; Lothar Hennighausen
Source: check_circle
Crossref

Immune transcriptomes of highly exposed SARS-CoV-2 asymptomatic seropositive versus seronegative individuals from the Ischgl community.

Scientific reports
2021-02-19 | Journal article
DOI: 10.1038/s41598-021-83110-6
PMID: 33608566
PMC: PMC7895922
Contributors: HYE KYUNG LEE
Source: Self-asserted source
HYE KYUNG LEE

Activation of Interferon-Stimulated Transcriptomes and ACE2 Isoforms in Human Airway Epithelium Is Curbed by Janus Kinase Inhibitors

2020-12-11 | Preprint
DOI: 10.21203/rs.3.rs-119695/v1
Contributors: Hye Kyung Lee; Olive Jung; Lothar Hennighausen
Source: check_circle
Crossref

Regulation of theACE2locus in human airways cells

2020-10-05 | Preprint
DOI: 10.1101/2020.10.04.325415
Contributors: Hye Kyung Lee; Olive Jung; Lothar Hennighausen
Source: check_circle
Crossref

Immune transcriptomes of highly exposed SARS-CoV-2 asymptomatic seropositive versus seronegative individuals from the Ischgl community

2020-09-23 | Other
DOI: 10.21203/rs.3.rs-69657/v1
Contributors: Hye Kyung Lee; Ludwig Knabl; Lisa Pipperger; Andre Volland; Priscilla Furth; Keunsoo Kang; Harold Smith; Ludwig Knabl; Romuald Bellmann; Christina Bernhard et al.
Source: check_circle
Crossref

Activation of the SARS-CoV-2 Receptor Ace2 through JAK/STAT-Dependent Enhancers during Pregnancy.

Cell reports
2020-09-06 | Journal article
DOI: 10.1016/j.celrep.2020.108199
PMID: 32966801
PMC: PMC7474886
Contributors: HYE KYUNG LEE
Source: Self-asserted source
HYE KYUNG LEE

Immune transcriptomes of highly exposed SARS-CoV-2 asymptomatic seropositive versus seronegative individuals from the Ischgl community

2020-09-02 | Other
DOI: 10.1101/2020.09.01.20185884
Contributors: Hye Kyung Lee; Ludwig Knabl; Lisa Pipperger; Andre Volland; Priscilla A. Furth; Keunsoo Kang; Harold E. Smith; Knabl Ludwig, Sr.; Romuald Bellmann; Christina Bernhard et al.
Source: check_circle
Crossref

Enhancer and super-enhancer dynamics in repair after ischemic acute kidney injury

Nature Communications
2020-07-07 | Journal article
DOI: 10.1038/s41467-020-17205-5
Contributors: Julia Wilflingseder; Michaela Willi; Hye Kyung Lee; Hannes Olauson; Jakub Jankowski; Takaharu Ichimura; Reinhold Erben; M. Todd Valerius; Lothar Hennighausen; Joseph V. Bonventre
Source: check_circle
Crossref

The transcription factor STAT5 binds to distinct super-enhancer sites and controlsLrrc32expression in a prominent autoimmune and allergic disease risk locus

2020-06-15 | Preprint
DOI: 10.1101/2020.06.13.150177
Contributors: Lothar Hennighausen; Hye Kyung Lee
Source: check_circle
Crossref
Items per page:
Page 1 of 2

Peer review (1 review for 1 publication/grant)

Review activity for Nature communications (1)
How many people are using ORCID?