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JEFFREY CHEAH SCHOOL OF MEDICINE AND HEALTH SCIENCES: JOHOR BAHRU, JOHOR, MY

2007 to present | ASSOCIATE PROFESSOR (MEDICINE)
Employment
Source: Self-asserted source
SIEW ENG CHOON

Education and qualifications (5)

Royal College of Physicians: London, London, GB

2003 to present | FRCP
Qualification
Source: Self-asserted source
SIEW ENG CHOON

University College London: London, London, GB

1988 to present | Diploma in Genitourinary Medicine
Qualification
Source: Self-asserted source
SIEW ENG CHOON

Saint John's Institute of Dermatology: London, London, GB

1987 to present | Diploma in Dermatology
Qualification
Source: Self-asserted source
SIEW ENG CHOON

Royal College of Physicians: London, London, GB

1987 to present | MRCP
Qualification
Source: Self-asserted source
SIEW ENG CHOON

University of Malaya: Kuala Lumpur, Wilayah Persekutuan, MY

1982 to present | MBBS
Education
Source: Self-asserted source
SIEW ENG CHOON

Works (50 of 73)

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Page 1 of 2

Correction: Analysis of Predefined Safety Events Across Spesolimab Trials in Dermatological and Non-Dermatological Conditions

Dermatology and Therapy
2025-04-05 | Journal article
Contributors: Kenneth B. Gordon; Yayoi Tada; Milan J. Anadkat; Siew Eng Choon; Boni Elewski; Jonathan N. Barker; Arash Mostaghimi; Kilian Eyerich; Ming Tang; Thomas Haeufel et al.
Source: check_circle
Crossref

Spesolimab Reduces Inflammation in Generalized Pustular Psoriasis: Molecular Characterization of Flare Treatment in EFFISAYIL 1

Journal of Investigative Dermatology
2025-03 | Journal article
Contributors: Ahmed Farag; Sudha Visvanathan; Hervé Bachelez; Akimichi Morita; Mark G. Lebwohl; Jonathan N. Barker; Siew Eng Choon; A. David Burden; Tsen-Fang Tsai; Germán Leparc et al.
Source: check_circle
Crossref

Global Delphi consensus on treatment goals for generalized pustular psoriasis

British Journal of Dermatology
2025-03-18 | Journal article
Contributors: Jonathan N Barker; Emmylou Casanova; Siew Eng Choon; Peter Foley; Hideki Fujita; César Gonzalez; Melinda Gooderham; Slaheddine Marrakchi; Luís Puig; Ricardo Romiti et al.
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Crossref

Analysis of Predefined Safety Events Across Spesolimab Trials in Dermatological and Non-Dermatological Conditions

Dermatology and Therapy
2025-02 | Journal article
Contributors: Kenneth B. Gordon; Yayoi Tada; Milan J. Anadkat; Siew Eng Choon; Boni Elewski; Jonathan N. Barker; Arash Mostaghimi; Kilian Eyerich; Ming Tang; Thomas Haeufel et al.
Source: check_circle
Crossref

Asia‐Pacific consensus recommendations on the management of generalized pustular psoriasis

The Journal of Dermatology
2024-12 | Journal article
Contributors: Siew Eng Choon; Peter Anthony Foley; Pravit Asawanonda; Hideki Fujita; Seong‐Jin Jo; Yu‐ling Shi; Colin Theng; Azura Mohd Affandi; Chul Hwan Bang; Maria Lorna Frez et al.
Source: check_circle
Crossref

Health‐related quality of life in patients with generalized pustular psoriasis: A systematic literature review

Journal of the European Academy of Dermatology and Venereology
2024-02 | Journal article
Contributors: S. E. Choon; C. De La Cruz; P. Wolf; R. K. Jha; K. I. Fischer; D. C. Goncalves‐Bradley; T. Hepworth; S. R. Marshall; A. B. Gottlieb
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Crossref

Incidence and prevalence of generalized pustular psoriasis in multiethnic Johor Bahru, Malaysia: a population-based cohort study using routinely captured electronic health records in the Teleprimary Care (TPC®) clinical information system from 2010 to 2020

British Journal of Dermatology
2023-09-15 | Journal article
Contributors: Siew Eng Choon; Alison K Wright; Christopher E M Griffiths; Kit Wan Wong; Kwee Eng  Tey; Yee Ting Lim; Keow Yin Chua; Darren M Ashcroft
Source: check_circle
Crossref

Clinical profile of patients with acute generalized pustular psoriasis with and without IL36RN mutations in multi‐ethnic Johor Bahru, Malaysia

Experimental Dermatology
2023-08 | Journal article
Contributors: Siew Eng Choon; Peter Seah Keng Tok; Kit Wan Wong; Yee Ting Lim; Nalini M. Nanu; Jonathan N. Barker; Francesca Capon
Source: check_circle
Crossref

Cover Image

Experimental Dermatology
2023-08 | Journal article
Contributors: Siew Eng Choon; Peter Seah Keng Tok; Kit Wan Wong; Yee Ting Lim; Nalini M. Nanu; Jonathan N. Barker; Francesca Capon
Source: check_circle
Crossref

Diversity in the clinical presentation of generalized pustular psoriasis (GPP): A series of case vignettes from around the world

Experimental Dermatology
2023-08 | Journal article
Contributors: Siew Eng Choon; Boni E. Elewski; Hideki Fujita; Songmei Geng; Peter van de Kerkhof; Sicily Mburu; Lluís Puig; Ricardo Romiti; Marina Venturini
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Crossref

Efficacy of spesolimab for the treatment of generalized pustular psoriasis flares across pre‐specified patient subgroups in the Effisayil 1 study

Experimental Dermatology
2023-08 | Journal article
Contributors: A. D. Burden; Y. Okubo; M. Zheng; D. Thaçi; P. van de Kerkhof; N. Hu; M. Quaresma; C. Thoma; S. E. Choon
Source: check_circle
Crossref

Understanding generalized pustular psoriasis for improved patient care

Experimental Dermatology
2023-08 | Journal article
Contributors: Siew Eng Choon; Jonathan Barker; Herve Bachelez
Source: check_circle
Crossref

The Generalized Pustular Psoriasis Physician Global Assessment (GPPGA) score: online assessment and validation study of a specific measure of GPP disease activity

British Journal of Dermatology
2023-07-07 | Journal article
Contributors: A David Burden; Hervé Bachelez; Siew Eng Choon; Slaheddine Marrakchi; Tsen-Fang Tsai; Hamida Turki; Akimichi Morita; Mark G Lebwohl; Robert Bissonnette; Min Zheng et al.
Source: check_circle
Crossref

Generalized pustular psoriasis: A global Delphi consensus on clinical course, diagnosis, treatment goals and disease management

Journal of the European Academy of Dermatology and Venereology
2023-04 | Journal article
Contributors: Lluís Puig; Siew Eng Choon; Alice B. Gottlieb; Slaheddine Marrakchi; Jörg C. Prinz; Ricardo Romiti; Yayoi Tada; Dorothea von Bredow; Melinda Gooderham
Source: check_circle
Crossref

Prevalence, comorbidities and mortality of generalized pustular psoriasis: A literature review

Journal of the European Academy of Dermatology and Venereology
2023-02 | Journal article
Contributors: Jörg C. Prinz; Siew Eng Choon; Christopher E. M. Griffiths; Joseph F. Merola; Akimichi Morita; Darren M. Ashcroft; Manuelle Viguier
Source: check_circle
Crossref

Incidence and prevalence of psoriasis in multiethnic Johor Bahru, Malaysia: a population-based cohort study using electronic health data routinely captured in the Teleprimary Care (TPC®) clinical information system from 2010 to 2020

British Journal of Dermatology
2022-11-01 | Journal article
Contributors: Siew Eng Choon; Alison K. Wright; Christopher E.M. Griffiths; Kwee Eng Tey; Kit Wan Wong; Yoong Wei Lee; Ushananthiny Suvelayutnan; Jeevitha Mariapun; Darren M. Ashcroft
Source: check_circle
Crossref

Time to accurately determine the burden of generalized pustular psoriasis at the population level

British Journal of Dermatology
2022-06 | Journal article
Contributors: Siew Eng Choon; Hervé Bachelez
Source: check_circle
Crossref

Clinical Disease Measures in Generalized Pustular Psoriasis

American Journal of Clinical Dermatology
2022-01 | Journal article
Contributors: A. David Burden; Siew Eng Choon; Alice B. Gottlieb; Alexander A. Navarini; Richard B. Warren
Source: check_circle
Crossref

Factors associated with adverse COVID-19 outcomes in patients with psoriasis-insights from a global registry-based study

Journal of Allergy and Clinical Immunology
2021 | Journal article
Contributors: Mahil, Satveer K.; Dand, Nick; Mason, Kayleigh J.; Yiu, Zenas Z. N.; Tsakok, Teresa; Meynell, Freya; Coker, Bola; McAteer, Helen; Moorhead, Lucy; Mackenzie, Teena et al.
Source: check_circle
Web of Science Researcher Profile Sync
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Preferred source (of 2)‎

Loss-of-function myeloperoxidase mutations are associated with increased neutrophil counts and pustular skin disease (vol 107, pg 539, 2020)

The American Journal of Human Genetics
2021 | Journal article
Contributors: Vergnano, Marta; Mockenhaupt, Maja; Benzian-Olsson, Natashia; Paulmann, Maren; Grys, Katarzyna; Mahil, Satveer K.; Chaloner, Charlotte; Barbosa, Ines A.; August, Suzannah; Burden, A. David et al.
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Web of Science Researcher Profile Sync
grade
Preferred source (of 2)‎

Study protocol of the global Effisayil 1 Phase II, multicentre, randomised, double-blind, placebo-controlled trial of spesolimab in patients with generalized pustular psoriasis presenting with an acute flare

BMJ Open
2021 | Journal article
Contributors: Choon, Siew Eng; Lebwohl, Mark G.; Marrakchi, Slaheddine; Burden, A. David; Tsai, Tsen-Fang; Morita, Akimichi; Navarini, Alexander A.; Zheng, Min; Xu, Jinhua; Turki, Hamida et al.
Source: check_circle
Web of Science Researcher Profile Sync
grade
Preferred source (of 2)‎

Whole genome sequencing identifies genetic variants associated with co-trimoxazole hypersensitivity in Asians

Journal of Allergy and Clinical Immunology
2021 | Journal article
Contributors: Wang, Chuang-Wei; Tassaneeyakul, Wichittra; Chen, Chun-Bing; Chen, Wei-Ti; Teng, Yu-Chuan; Huang, Cheng-Yang; Sukasem, Chonlaphat; Lu, Chun-Wei; Lee, Yun-Shien; Choon, Siew-Eng et al.
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Web of Science Researcher Profile Sync
grade
Preferred source (of 2)‎

Trial of spesolimab for generalized pustular psoriasis

The New England Journal of Medicine
2021-12-23 | Journal article | Author
SOURCE-WORK-ID:

78cb93c1-7ad5-4bc7-9618-59278fea2530

EID:

2-s2.0-85122106967

Contributors: Hervé Bachelez; SIEW ENG CHOON; Slaheddine Marrakchi; A. David Burden; Tsen Fang Tsai; Akimichi Morita; Alexander A. Navarini; Min Zheng; Jinhua Xu; Hamida Turki et al.
Source: check_circle
Monash University

Loss-of-Function Myeloperoxidase Mutations Are Associated with Increased Neutrophil Counts and Pustular Skin Diseasek

The American Journal of Human Genetics
2020 | Journal article
Contributors: Vergnano, Marta; Mockenhaupt, Maja; Benzian-Olsson, Natashia; Paulmann, Maren; Grys, Katarzyna; Mahil, Satveer K.; Chaloner, Charlotte; Barbosa, Ines A.; August, Suzannah; Burden, A. David et al.
Source: check_circle
Web of Science Researcher Profile Sync
grade
Preferred source (of 2)‎

IL-36 Promotes Systemic IFN-I Responses in Severe Forms of Psoriasis

Journal of Investigative Dermatology
2020-04 | Journal article
Contributors: Marika Catapano; Marta Vergnano; Marco Romano; Satveer K. Mahil; Siew-Eng Choon; A. David Burden; Helen S. Young; Ian M. Carr; Helen J. Lachmann; Giovanna Lombardi et al.
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Crossref
grade
Preferred source (of 3)‎

CLINICAL CHARACTERISTICS, CULPRIT DRUGS AND OUTCOME OF PATIENTS WITH ACUTE GENERALISED EXANTHEMATOUS PUSTULOSIS SEEN IN HOSPITAL SULTANAH AMINAH, JOHOR BAHRU, MALAYSIA

Internal Medicine Journal
2019 | Journal article
Contributors: Choon, Siew Eng; Der, Yi Shan; Lai, Nai Liang Joel; Yu, Evelyn Sing Ee; Yap, Xiao Ling; Madhavan, Nalini Nanu
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Web of Science Researcher Profile Sync

Inhibition of the Interleukin-36 Pathway for the Treatment of Generalized Pustular Psoriasis

New England Journal of Medicine
2019 | Journal article
Contributors: Bachelez, Herve; Choon, Siew-Eng; Marrakchi, Slaheddine; Burden, A. David; Tsai, Tsen-Fang; Morita, Akimichi; Turki, Hamida; Hall, David B.; Shear, Michael; Baum, Patrick et al.
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Web of Science Researcher Profile Sync
grade
Preferred source (of 2)‎

Serum 25-hydroxyvitamin D deficiency in Malaysian children with severe atopic dermatitis

Medical Journal of Malaysia
2019-08 | Journal article | Author
SOURCE-WORK-ID:

5bed8680-470f-4bde-ade7-103c8dc63088

EID:

2-s2.0-85071472872

Contributors: Yoong Wei Lee; SIEW ENG CHOON; Shahannim Izham
Source: check_circle
Monash University

Clinical and genetic differences between pustular psoriasis subtypes

Journal of Allergy and Clinical Immunology
2018 | Journal article
EID:

2-s2.0-85051522281

Contributors: Twelves, S.; Mostafa, A.; Dand, N.; Burri, E.; Farkas, K.; Wilson, R.; Cooper, H.L.; Irvine, A.D.; Oon, H.H.; Kingo, K. et al.
Source: Self-asserted source
SIEW ENG CHOON via Scopus - Elsevier
grade
Preferred source (of 3)‎

Clinical characteristics, culprit drugs and outcome of patients with acute generalised exanthematous pustulosis seen in hospital sultanah aminah, johor bahru

Medical Journal of Malaysia
2018 | Journal article
EID:

2-s2.0-85051858818

Contributors: Choon, S.E.; Der, Y.S.; Lai, N.L.J.; Yu, E.S.E.; Yap, X.L.; Madhavan, N.N.
Source: Self-asserted source
SIEW ENG CHOON via Scopus - Elsevier
grade
Preferred source (of 2)‎

Erythematous verrucous plaque on the hand

Cutis
2018 | Journal article
EID:

2-s2.0-85054988466

Contributors: Yee, E.Y.W.; Choon, S.E.
Source: Self-asserted source
SIEW ENG CHOON via Scopus - Elsevier
grade
Preferred source (of 2)‎

Erythematous Verrucous Plaque on the Hand Chromomycosis

Cutis
2018 | Journal article
Contributors: Yee, Evelyn Yap Wen; Choon, Siew Eng
Source: check_circle
Web of Science Researcher Profile Sync

Features of pustular psoriasis observed in 863 patients: Clinical and genetic analysis of a multi-ethnic cohort

Journal of Investigative Dermatology
2018 | Journal article
Contributors: Twelves, S.; Mostafa, A.; Bata-Csorg, Z.; Szell, M.; Griffiths, C. E. M.; Burden, D.; Choon, S.; Smith, C.; Navarini, A.; Barker, J. et al.
Source: check_circle
Web of Science Researcher Profile Sync

The Function of HLA-B*13:01 Involved in the Pathomechanism of Dapsone-Induced Severe Cutaneous Adverse Reactions

Journal of Investigative Dermatology
2018 | Journal article
EID:

2-s2.0-85044984507

Contributors: Chen, W.-T.; Wang, C.-W.; Lu, C.-W.; Chen, C.-B.; Lee, H.-E.; Hung, S.-I.; Choon, S.-E.; Yang, C.-H.; Liu, M.-T.; Chen, T.J. et al.
Source: Self-asserted source
SIEW ENG CHOON via Scopus - Elsevier
grade
Preferred source (of 3)‎

The Medication Risk of Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis in Asians: The Major Drug Causality and Comparison With the US FDA Label

Clinical Pharmacology and Therapeutics
2018 | Journal article
EID:

2-s2.0-85052614824

Contributors: Wang, Y.-H.; Chen, C.-B.; Tassaneeyakul, W.; Saito, Y.; Aihara, M.; Choon, S.E.; Lee, H.Y.; Chang, M.M.; Roa, F.D.; Wu, C.-W. et al.
Source: Self-asserted source
SIEW ENG CHOON via Scopus - Elsevier
grade
Preferred source (of 3)‎

Towards global consensus on core outcomes for hidradenitis suppurativa research: an update from the HISTORIC consensus meetings I and II

British Journal of Dermatology
2018 | Journal article
EID:

2-s2.0-85037057845

Contributors: Thorlacius, L.; Garg, A.; Ingram, J.R.; Villumsen, B.; Theut Riis, P.; Gottlieb, A.B.; Merola, J.F.; Dellavalle, R.; Ardon, C.; Baba, R. et al.
Source: Self-asserted source
SIEW ENG CHOON via Scopus - Elsevier
grade
Preferred source (of 3)‎

Association of HLA-B∗15:13 and HLA-B∗15:02 with phenytoin-induced severe cutaneous adverse reactions in a Malay population

Pharmacogenomics Journal
2017 | Journal article
EID:

2-s2.0-84959528710

Contributors: Chang, C.-C.; Ng, C.-C.; Too, C.-L.; Choon, S.-E.; Lee, C.-K.; Chung, W.-H.; Hussein, S.H.; Lim, K.-S.; Murad, S.
Source: Self-asserted source
SIEW ENG CHOON via Scopus - Elsevier
grade
Preferred source (of 3)‎

Clinical features and prognostic factors of cutaneous vasculitis among dermatology patients in johor bahru, Malaysia

Medical Journal of Malaysia
2017 | Journal article
EID:

2-s2.0-85042549669

Contributors: Selvarajah, L.R.; Choon, S.E.; Tey, K.E.; Chee, Y.N.
Source: Self-asserted source
SIEW ENG CHOON via Scopus - Elsevier
grade
Preferred source (of 2)‎

Incidence of cutaneous adverse drug reactions among medical inpatients of Sultanah Aminah hospital Johor Bahru

Medical Journal of Malaysia
2017 | Journal article
EID:

2-s2.0-85025649185

Contributors: Selvarajah, L.R.; Choon, S.E.
Source: Self-asserted source
SIEW ENG CHOON via Scopus - Elsevier
grade
Preferred source (of 2)‎

Juvenile generalized pustular psoriasis is a chronic recalcitrant disease: an analysis of 27 patients seen in a tertiary hospital in Johor, Malaysia

International Journal of Dermatology
2017 | Journal article
EID:

2-s2.0-85013032038

Contributors: Lau, B.-W.; Lim, D.-Z.; Capon, F.; Barker, J.N.; Choon, S.-E.
Source: Self-asserted source
SIEW ENG CHOON via Scopus - Elsevier
grade
Preferred source (of 3)‎

The genetic analysis of a large pustular psoriasis resource highlights differential effects for <i>IL36RN</i> and <i>AP1S3</i> mutations

British Journal of Dermatology
2017 | Journal article
Contributors: Twelves, S.; Farkas, K.; Choon, S. E.; Burden, D.; Griffiths, C. E. M.; Irvine, A.; Tan, E.; Szell, M.; Bata-Csorgo, Z.; Smith, C. et al.
Source: check_circle
Web of Science Researcher Profile Sync

Widespread Indurated Plaques and Nodules

Indian Journal of Dermatology
2017 | Journal article
Contributors: Yap, Evelyn; Lee, Senhong; Tey, Kwee Eng; Choon, Siew Eng
Source: check_circle
Web of Science Researcher Profile Sync

AP1S3 Mutations Cause Skin Autoinflammation by Disrupting Keratinocyte Autophagy and Up-Regulating IL-36 Production

Journal of Investigative Dermatology
2016 | Journal article
EID:

2-s2.0-84994745820

Contributors: Mahil, S.K.; Twelves, S.; Farkas, K.; Setta-Kaffetzi, N.; Burden, A.D.; Gach, J.E.; Irvine, A.D.; Képíró, L.; Mockenhaupt, M.; Oon, H.H. et al.
Source: Self-asserted source
SIEW ENG CHOON via Scopus - Elsevier
grade
Preferred source (of 3)‎

Cerebral tuberculoma with pulmonary tuberculosis in a patient with psoriasis treated with adalimumab, an anti-tumor necrosis factor-α agent

International Journal of Dermatology
2016 | Journal article
EID:

2-s2.0-84954389222

Contributors: Selvarajah, L.; Choon, S.E.; Tarekh, N.A.; Chhetri, A.D.
Source: Self-asserted source
SIEW ENG CHOON via Scopus - Elsevier
grade
Preferred source (of 3)‎

Clinico-epidemiological profile, including body mass index of Malaysian children with psoriasis

Medical Journal of Malaysia
2016 | Journal article
EID:

2-s2.0-84992143121

Contributors: Choon, S.E.; Ngim, C.F.; Supramaniam, P.; Tey, K.E.; Madhavan, N.N.
Source: Self-asserted source
SIEW ENG CHOON via Scopus - Elsevier
grade
Preferred source (of 2)‎

First report of digenic inheritance in pustular psoriasis

Journal of Investigative Dermatology
2016 | Journal article
Contributors: Twelves, S.; Burden, D.; Marta, S.; Bata-Csorgo, Z.; Choon, S.; Mockenhaupt, M.; Smith, C. H.; Capon, F.; Barker, J.
Source: check_circle
Web of Science Researcher Profile Sync

Rosai-dorfman disease with autoimmune haemolytic anaemia in an adult

Australasian Journal of Dermatology
2016 | Journal article
Contributors: Lee, S.; Yap, E.; Tey, K. E.; Choon, S. E.
Source: check_circle
Web of Science Researcher Profile Sync

The MARCOPOLO study of ustekinumab utilization and efficacy in a real-world setting: Treatment of patients with plaque psoriasis in Asia-pacific countries

Annals of Dermatology
2016 | Journal article
EID:

2-s2.0-84963512342

Contributors: Youn, S.W.; Tsai, T.-F.; Theng, C.; Choon, S.-E.; Wiryadi, B.E.; Pires, A.; Tan, W.; Lee, M.-G.
Source: Self-asserted source
SIEW ENG CHOON via Scopus - Elsevier
grade
Preferred source (of 3)‎

Activating CARD14 mutations are associated with generalized pustular psoriasis but rarely account for familial recurrence in psoriasis vulgaris

Journal of Investigative Dermatology
2015 | Journal article
EID:

2-s2.0-84948712112

Contributors: Berki, D.M.; Liu, L.; Choon, S.-E.; Burden, A.D.; Griffiths, C.E.M.; Navarini, A.A.; Tan, E.S.; Irvine, A.D.; Ranki, A.; Ogo, T. et al.
Source: Self-asserted source
SIEW ENG CHOON via Scopus - Elsevier
grade
Preferred source (of 3)‎

Genetic analysis of <i>CARD14</i> mutations in an extended pustular psoriasis resource

British Journal of Dermatology
2015 | Journal article
Contributors: Berki, D.; Burden, D.; Choon, S. E.; Allen, M.; Seyger, M.; Smith, C.; Capon, F.; Barker, J.
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Items per page:
Page 1 of 2

Peer review (26 reviews for 13 publications/grants)

Review activity for American journal of clinical dermatology. (3)
Review activity for Australasian journal of dermatology (1)
Review activity for BioDrugs. (1)
Review activity for BioDrugs. (1)
Review activity for British journal of dermatology (3)
Review activity for Clinical and experimental dermatology (1)
Review activity for Experimental dermatology. (1)
Review activity for International journal of dermatology. (1)
Review activity for Journal of clinical medicine. (1)
Review activity for Journal of dermatological treatment. (2)
Review activity for Journal of psoriasis and psoriatic arthritis. (2)
Review activity for Journal of the European Academy of Dermatology and Venereology : (8)
Review activity for Skin health and disease. (1)