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Employment (1)

University of Texas MD Anderson Cancer Center: Houston, TX, US

2021-10-01 to present | Assistant Professor (Lymphoma & Myeloma)
Employment
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Heng-Huan Lee

Works (6)

Targeting ALK averts ribonuclease 1-induced immunosuppression and enhances antitumor immunity in hepatocellular carcinoma

Nature Communications
2024-02-02 | Journal article
DOI: 10.1038/s41467-024-45215-0
Contributors: Chunxiao Liu; Chenhao Zhou; Weiya Xia; Yifan Zhou; Yufan Qiu; Jialei Weng; Qiang Zhou; Wanyong Chen; Ying-Nai Wang; Heng-Huan Lee et al.
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Crossref

Dual targeting of CDK4/6 and Bcl-2 exhibits a potent antitumor effect on mantle cell lymphoma

Blood Advances
2023-07-25 | Journal article
DOI: 10.1182/bloodadvances.2022008954
Contributors: Yuxuan Che; Yang Liu; Yijing Li; Joseph M. McIntosh; Alexa Jordan; Fangfang Yan; Wei Wang; Lei Nie; Heng-Huan Lee; Jingling Jin et al.
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Crossref

Targeting the ALK–CDK9-Tyr19 kinase cascade sensitizes ovarian and breast tumors to PARP inhibition via destabilization of the P-TEFb complex

Nature Cancer
2022-10-17 | Journal article
DOI: 10.1038/s43018-022-00438-2
Contributors: Yu-Yi Chu; Mei-Kuang Chen; Yongkun Wei; Heng-Huan Lee; Weiya Xia; Ying-Nai Wang; Clinton Yam; Jennifer L. Hsu; Hung-Ling Wang; Wei-Chao Chang et al.
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Crossref

Human ribonuclease 1 serves as a secretory ligand of ephrin A4 receptor and induces breast tumor initiation

Nature Communications
2021-05-13 | Journal article
DOI: 10.1038/s41467-021-23075-2
Contributors: Heng-Huan Lee; Ying-Nai Wang; Wen-Hao Yang; Weiya Xia; Yongkun Wei; Li-Chuan Chan; Yu-Han Wang; Zhou Jiang; Shouping Xu; Jun Yao et al.
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Crossref

TYRO3 induces anti–PD-1/PD-L1 therapy resistance by limiting innate immunity and tumoral ferroptosis

Journal of Clinical Investigation
2021-04-15 | Journal article
DOI: 10.1172/JCI139434
Contributors: Zhou Jiang; Seung-Oe Lim; Meisi Yan; Jennifer L. Hsu; Jun Yao; Yongkun Wei; Shih-Shin Chang; Hirohito Yamaguchi; Heng-Huan Lee; Baozhen Ke et al.
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Crossref

IL-6/JAK1 pathway drives PD-L1 Y112 phosphorylation to promote cancer immune evasion

Journal of Clinical Investigation
2019-07-15 | Journal article
DOI: 10.1172/JCI126022
Contributors: Li-Chuan Chan; Chia-Wei Li; Weiya Xia; Jung-Mao Hsu; Heng-Huan Lee; Jong-Ho Cha; Hung-Ling Wang; Wen-Hao Yang; Er-Yen Yen; Wei-Chao Chang et al.
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Crossref
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