Personal information

Chromatin; Transcription; RNA polymerase I; Ribosome biogenesis
Germany

Biography

since 2016 Associate Professor at the NWFIII at the University of Regensburg, Lehrstuhl Biochemie III
since 2010 Permanent academic staff member (principal investigator) at the University of Regensburg (Germany), Lehrstuhl Biochemie III
2006 - 2010 Habilitation in Biochemistry at the NWFIII at the University of Regensburg (Germany)
2004 - 2010 Group Leader at the University of Regensburg (Germany), Lehrstuhl Biochemie III
2003 - 2004 Life Science Research Associate at Stanford University (U.S.A.), Department of Structural Biology, Laboratory of Prof. Dr. Roger D. Kornberg
1998 - 2003 Postdoctoral Researcher at Stanford University (U.S.A.), Department of Structural Biology, Laboratory of Prof. Dr. Roger D. Kornberg
1994 - 1998 Ph.D. Thesis at the Free University of Berlin (Germany), Institut für Biochemie, Laboratory of Prof. Dr. Dr. Manfred Schweiger

Activities

Employment (1)

Institut für Biochemie, Genetik und Mikrobiologie, Universität Regensburg: Regensburg, Bavaria, DE

2004-09-01 to present | Associate Professor (Biochemie III)
Employment
Source: Self-asserted source
Joachim Griesenbeck

Works (50 of 55)

Items per page:
Page 1 of 2

Features of yeast RNA polymerase I with special consideration of the lobe binding subunits

Biological Chemistry
2023-10-26 | Journal article
Contributors: Katrin Schwank; Catharina Schmid; Tobias Fremter; Christoph Engel; Philipp Milkereit; Joachim Griesenbeck; Herbert Tschochner
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Crossref

Synthesis of the ribosomal RNA precursor in human cells: mechanisms, factors and regulation

Biological Chemistry
2023-10-26 | Journal article
Contributors: Julia L. Daiß; Joachim Griesenbeck; Herbert Tschochner; Christoph Engel
Source: check_circle
Crossref

Impact of the yeast S0/uS2-cluster ribosomal protein rpS21/eS21 on rRNA folding and the architecture of small ribosomal subunit precursors

PLOS ONE
2023-03-30 | Journal article
Contributors: Gisela Pöll; Hyun Ho Park; Joachim Griesenbeck; Herbert Tschochner; Philipp Milkereit
Source: check_circle
Crossref

Impact of the yeast S0/uS2-cluster ribosomal protein rpS21/eS21 on rRNA folding and the architecture of small ribosomal subunit precursors

2023-01-18 | Preprint
Contributors: Gisela Pöll; Joachim Griesenbeck; Herbert Tschochner; Philipp Milkereit
Source: check_circle
Crossref

RNA polymerase I (Pol I) lobe-binding subunit Rpa12.2 promotes RNA cleavage and proofreading

Journal of Biological Chemistry
2022-05 | Journal article
Contributors: Katrin Schwank; Catharina Schmid; Tobias Fremter; Philipp Milkereit; Joachim Griesenbeck; Herbert Tschochner
Source: check_circle
Crossref

Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors

PLOS ONE
2021-11-23 | Journal article
Contributors: Gisela Pöll; Thomas Preiss; Michael Pilsl; Joachim Griesenbeck; Herbert Tschochner; Philipp Milkereit
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Crossref

Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors

2021-05-18 | Other
Contributors: Gisela Pöll; Michael Pilsl; Joachim Griesenbeck; Herbert Tschochner; Philipp Milkereit
Source: check_circle
Crossref

Effects of polyploidy on the coordination of gene expression between organellar and nuclear genomes in Leucanthemum Mill. (Compositae, Anthemideae)

Ecology and Evolution
2019-08 | Journal article
Contributors: Christoph Oberprieler; Martina Talianova; Joachim Griesenbeck
Source: check_circle
Crossref

The C-terminal region of Net1 is an activator of RNA polymerase I transcription with conserved features from yeast to human

PLOS Genetics
2019-02-25 | Journal article
Part of ISSN: 1553-7404
Source: Self-asserted source
Joachim Griesenbeck

ALY RNA-Binding Proteins Are Required for Nucleocytosolic mRNA Transport and Modulate Plant Growth and Development

Plant Physiology
2018-05 | Journal article
Contributors: Christina Pfaff; Hans F. Ehrnsberger; María Flores-Tornero; Brian B. Sørensen; Thomas Schubert; Gernot Längst; Joachim Griesenbeck; Stefanie Sprunck; Marion Grasser; Klaus D. Grasser
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Crossref

Analysis of In Vivo Chromatin and Protein Interactions of Arabidopsis Transcript Elongation Factors.

2017 | Journal article
Contributors: Pfab A; Antosz W; Holzinger P; Bruckmann A; Griesenbeck J; Grasser KD
Source: Self-asserted source
Joachim Griesenbeck via Europe PubMed Central

Structural transitions during large ribosomal subunit maturation analyzed by tethered nuclease structure probing in S. cerevisiae.

2017 | Journal article
Contributors: Pöll G; Müller C; Bodden M; Teubl F; Eichner N; Lehmann G; Griesenbeck J; Tschochner H; Milkereit P
Source: Self-asserted source
Joachim Griesenbeck via Europe PubMed Central

Structure and Function of RNA Polymerases and the Transcription Machineries.

2017 | Journal article
Contributors: Griesenbeck J; Tschochner H; Grohmann D
Source: Self-asserted source
Joachim Griesenbeck via Europe PubMed Central

The Composition of the Arabidopsis RNA Polymerase II Transcript Elongation Complex Reveals the Interplay between Elongation and mRNA Processing Factors

The Plant Cell
2017-04 | Journal article
Contributors: Wojciech Antosz; Alexander Pfab; Hans F. Ehrnsberger; Philipp Holzinger; Karin Köllen; Simon A. Mortensen; Astrid Bruckmann; Thomas Schubert; Gernot Längst; Joachim Griesenbeck et al.
Source: check_circle
Crossref

Analysis of S. cerevisiae RNA Polymerase I Transcription In Vitro.

2016 | Journal article
Contributors: Pilsl M; Merkl PE; Milkereit P; Griesenbeck J; Tschochner H
Source: Self-asserted source
Joachim Griesenbeck via Europe PubMed Central

Structure of the initiation-competent RNA polymerase I and its implication for transcription.

2016 | Journal article
Contributors: Pilsl M; Crucifix C; Papai G; Krupp F; Steinbauer R; Griesenbeck J; Milkereit P; Tschochner H; Schultz P
Source: Self-asserted source
Joachim Griesenbeck via Europe PubMed Central

Prenatal Exposure to Nitrosatable Drugs, Dietary Intake of Nitrites, and Preterm Birth.

2016-04 | Journal article
Contributors: Vuong AM; Shinde MU; Brender JD; Shipp EM; Huber JC; Sharkey JR; McDonald TJ; Werler MM; Kelley KE; Griesenbeck JS et al.
Source: Self-asserted source
Joachim Griesenbeck via Europe PubMed Central

Chromatin Endogenous Cleavage (ChEC) as a Method to Quantify Protein Interaction with Genomic DNA in Saccharomyces cerevisiae.

2015 | Journal article
Contributors: Babl V; Stöckl U; Tschochner H; Milkereit P; Griesenbeck J
Source: Self-asserted source
Joachim Griesenbeck via Europe PubMed Central

Chromatin structure analysis of single gene molecules by psoralen cross-linking and electron microscopy.

2015 | Journal article
Contributors: Brown CR; Eskin JA; Hamperl S; Griesenbeck J; Jurica MS; Boeger H
Source: Self-asserted source
Joachim Griesenbeck via Europe PubMed Central

Studies on the Coordination of Ribosomal Protein Assembly Events Involved in Processing and Stabilization of Yeast Early Large Ribosomal Subunit Precursors.

2015 | Journal article
Contributors: Ohmayer U; Gil-Hernández Á; Sauert M; Martín-Marcos P; Tamame M; Tschochner H; Griesenbeck J; Milkereit P
Source: Self-asserted source
Joachim Griesenbeck via Europe PubMed Central

Purification of specific chromatin domains from single-copy gene loci in Saccharomyces cerevisiae.

2014 | Journal article
Contributors: Hamperl S; Brown CR; Perez-Fernandez J; Huber K; Wittner M; Babl V; Stöckl U; Boeger H; Tschochner H; Milkereit P et al.
Source: Self-asserted source
Joachim Griesenbeck via Europe PubMed Central

Binding of the termination factor Nsi1 to its cognate DNA site is sufficient to terminate RNA polymerase I transcription in vitro and to induce termination in vivo.

2014-10 | Journal article
Contributors: Merkl P; Perez-Fernandez J; Pilsl M; Reiter A; Williams L; Gerber J; Böhm M; Deutzmann R; Griesenbeck J; Milkereit P et al.
Source: Self-asserted source
Joachim Griesenbeck via Europe PubMed Central

Compositional and structural analysis of selected chromosomal domains from Saccharomyces cerevisiae.

2014-01 | Journal article
Contributors: Hamperl S; Brown CR; Garea AV; Perez-Fernandez J; Bruckmann A; Huber K; Wittner M; Babl V; Stoeckl U; Deutzmann R et al.
Source: Self-asserted source
Joachim Griesenbeck via Europe PubMed Central

UV light-induced DNA lesions cause dissociation of yeast RNA polymerases-I and establishment of a specialized chromatin structure at rRNA genes.

2014-01 | Journal article
Contributors: Tremblay M; Charton R; Wittner M; Levasseur G; Griesenbeck J; Conconi A
Source: Self-asserted source
Joachim Griesenbeck via Europe PubMed Central

Chromatin states at ribosomal DNA loci.

2013 | Journal article
Contributors: Hamperl S; Wittner M; Babl V; Perez-Fernandez J; Tschochner H; Griesenbeck J
Source: Self-asserted source
Joachim Griesenbeck via Europe PubMed Central

RNA polymerase I termination: Where is the end?

2013 | Journal article
Contributors: Németh A; Perez-Fernandez J; Merkl P; Hamperl S; Gerber J; Griesenbeck J; Tschochner H
Source: Self-asserted source
Joachim Griesenbeck via Europe PubMed Central

Studies on the assembly characteristics of large subunit ribosomal proteins in S. cerevisae.

2013 | Journal article
Contributors: Ohmayer U; Gamalinda M; Sauert M; Ossowski J; Pöll G; Linnemann J; Hierlmeier T; Perez-Fernandez J; Kumcuoglu B; Leger-Silvestre I et al.
Source: Self-asserted source
Joachim Griesenbeck via Europe PubMed Central

Rrp5p, Noc1p and Noc2p form a protein module which is part of early large ribosomal subunit precursors in S. cerevisiae.

2013-01 | Journal article
Contributors: Hierlmeier T; Merl J; Sauert M; Perez-Fernandez J; Schultz P; Bruckmann A; Hamperl S; Ohmayer U; Rachel R; Jacob A et al.
Source: Self-asserted source
Joachim Griesenbeck via Europe PubMed Central

Chromatin endogenous cleavage and psoralen crosslinking assays to analyze rRNA gene chromatin in vivo.

2012 | Journal article
Contributors: Griesenbeck J; Wittner M; Charton R; Conconi A
Source: Self-asserted source
Joachim Griesenbeck via Europe PubMed Central

Interrelationships between yeast ribosomal protein assembly events and transient ribosome biogenesis factors interactions in early pre-ribosomes.

2012 | Journal article
Contributors: Jakob S; Ohmayer U; Neueder A; Hierlmeier T; Perez-Fernandez J; Hochmuth E; Deutzmann R; Griesenbeck J; Tschochner H; Milkereit P
Source: Self-asserted source
Joachim Griesenbeck via Europe PubMed Central

Local tertiary structure probing of ribonucleoprotein particles by nuclease fusion proteins.

2012 | Journal article
Contributors: Ohmayer U; Perez-Fernandez J; Hierlmeier T; Pöll G; Williams L; Griesenbeck J; Tschochner H; Milkereit P
Source: Self-asserted source
Joachim Griesenbeck via Europe PubMed Central

The Reb1-homologue Ydr026c/Nsi1 is required for efficient RNA polymerase I termination in yeast.

2012-08 | Journal article
Contributors: Reiter A; Hamperl S; Seitz H; Merkl P; Perez-Fernandez J; Williams L; Gerber J; Németh A; Léger I; Gadal O et al.
Source: Self-asserted source
Joachim Griesenbeck via Europe PubMed Central

Selective removal of promoter nucleosomes by the RSC chromatin-remodeling complex.

2011-07 | Journal article
Contributors: Lorch Y; Griesenbeck J; Boeger H; Maier-Davis B; Kornberg RD
Source: Self-asserted source
Joachim Griesenbeck via Europe PubMed Central

Establishment and maintenance of alternative chromatin states at a multicopy gene locus.

2011-05 | Journal article
Contributors: Wittner M; Hamperl S; Stöckl U; Seufert W; Tschochner H; Milkereit P; Griesenbeck J
Source: Self-asserted source
Joachim Griesenbeck via Europe PubMed Central

Occlusion of regulatory sequences by promoter nucleosomes in vivo.

2011-03 | Journal article
Contributors: Mao C; Brown CR; Griesenbeck J; Boeger H
Source: Self-asserted source
Joachim Griesenbeck via Europe PubMed Central

Reduction in ribosomal protein synthesis is sufficient to explain major effects on ribosome production after short-term TOR inactivation in Saccharomyces cerevisiae.

2011-02 | Journal article
Contributors: Reiter A; Steinbauer R; Philippi A; Gerber J; Tschochner H; Milkereit P; Griesenbeck J
Source: Self-asserted source
Joachim Griesenbeck via Europe PubMed Central

TOR-dependent reduction in the expression level of Rrn3p lowers the activity of the yeast RNA Pol I machinery, but does not account for the strong inhibition of rRNA production.

2010-09 | Journal article
Contributors: Philippi A; Steinbauer R; Reiter A; Fath S; Leger-Silvestre I; Milkereit P; Griesenbeck J; Tschochner H
Source: Self-asserted source
Joachim Griesenbeck via Europe PubMed Central

Alternative chromatin structures of the 35S rRNA genes in Saccharomyces cerevisiae provide a molecular basis for the selective recruitment of RNA polymerases I and II.

2010-04 | Journal article
Contributors: Goetze H; Wittner M; Hamperl S; Hondele M; Merz K; Stoeckl U; Griesenbeck J
Source: Self-asserted source
Joachim Griesenbeck via Europe PubMed Central

Actively transcribed rRNA genes in S. cerevisiae are organized in a specialized chromatin associated with the high-mobility group protein Hmo1 and are largely devoid of histone molecules.

2008-05 | Journal article
Contributors: Merz K; Hondele M; Goetze H; Gmelch K; Stoeckl U; Griesenbeck J
Source: Self-asserted source
Joachim Griesenbeck via Europe PubMed Central

Nucleosome retention and the stochastic nature of promoter chromatin remodeling for transcription.

2008-05 | Journal article
Contributors: Boeger H; Griesenbeck J; Kornberg RD
Source: Self-asserted source
Joachim Griesenbeck via Europe PubMed Central

Site specific phosphorylation of yeast RNA polymerase I.

2008-02 | Journal article
Contributors: Gerber J; Reiter A; Steinbauer R; Jakob S; Kuhn CD; Cramer P; Griesenbeck J; Milkereit P; Tschochner H
Source: Self-asserted source
Joachim Griesenbeck via Europe PubMed Central

Structural basis of eukaryotic gene transcription.

2005-02 | Journal article
Contributors: Boeger H; Bushnell DA; Davis R; Griesenbeck J; Lorch Y; Strattan JS; Westover KD; Kornberg RD
Source: Self-asserted source
Joachim Griesenbeck via Europe PubMed Central

Purification of defined chromosomal domains.

2004 | Journal article
Contributors: Griesenbeck J; Boeger H; Strattan JS; Kornberg RD
Source: Self-asserted source
Joachim Griesenbeck via Europe PubMed Central

Removal of promoter nucleosomes by disassembly rather than sliding in vivo.

2004-06 | Journal article
Contributors: Boeger H; Griesenbeck J; Strattan JS; Kornberg RD
Source: Self-asserted source
Joachim Griesenbeck via Europe PubMed Central

Affinity purification of specific chromatin segments from chromosomal loci in yeast.

2003-12 | Journal article
Contributors: Griesenbeck J; Boeger H; Strattan JS; Kornberg RD
Source: Self-asserted source
Joachim Griesenbeck via Europe PubMed Central

Nucleosomes unfold completely at a transcriptionally active promoter.

2003-06 | Journal article
Contributors: Boeger H; Griesenbeck J; Strattan JS; Kornberg RD
Source: Self-asserted source
Joachim Griesenbeck via Europe PubMed Central

A trithorax-group complex purified from Saccharomyces cerevisiae is required for methylation of histone H3.

2002-01 | Journal article
Contributors: Nagy PL; Griesenbeck J; Kornberg RD; Cleary ML
Source: Self-asserted source
Joachim Griesenbeck via Europe PubMed Central

A novel human DNA-binding protein with sequence similarity to a subfamily of redox proteins which is able to repress RNA-polymerase-III-driven transcription of the Alu-family retroposons in vitro.

1999-03 | Journal article
Contributors: Kropotov A; Sedova V; Ivanov V; Sazeeva N; Tomilin A; Krutilina R; Oei SL; Griesenbeck J; Buchlow G; Tomilin N
Source: Self-asserted source
Joachim Griesenbeck via Europe PubMed Central

Stimulation of the catalytic activity of poly(ADP-ribosyl) transferase by transcription factor Yin Yang 1.

1999-01 | Journal article
PMID: 9928945
Contributors: Griesenbeck J; Ziegler M; Tomilin N; Schweiger M; Oei SL
Source: Self-asserted source
Joachim Griesenbeck via Europe PubMed Central

Regulation of RNA polymerase II-dependent transcription by poly(ADP-ribosyl)ation of transcription factors.

1998-11 | Journal article
PMID: 9822623
Contributors: Oei SL; Griesenbeck J; Schweiger M; Ziegler M
Source: Self-asserted source
Joachim Griesenbeck via Europe PubMed Central
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Peer review (2 reviews for 2 publications/grants)

Review activity for PLOS genetics. (1)
Review activity for Seminars in cell & developmental biology. (1)