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Pestones A and B from a Fungus Pestalotiopsis sp. Bound to Mutant p53 and Changed Its Conformation

Journal of Natural Products
2025-02-28 | Journal article
DOI: 10.1021/acs.jnatprod.4c01440
Contributors: Yusaku Sadahiro; Misaki Okubo; Yuki Hitora; Natsuko Hitora-Imamura; Shunsuke Kotani; Sachiko Tsukamoto
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Crossref

Machine Learning Accelerates Screening of Osteoclast Differentiation Inhibitors from Natural Products

Journal of Natural Products
2024-10-25 | Journal article
DOI: 10.1021/acs.jnatprod.4c00640
Contributors: Yuki Hitora; Mako Hokaguchi; Yusaku Sadahiro; Takumi Higaki; Sachiko Tsukamoto
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A new linear peptide, higapeptin, isolated from the mud flat-derived fungus Acremonium persicinum inhibits mitochondrial energy metabolism

Journal of Natural Medicines
2024-06 | Journal article
DOI: 10.1007/s11418-024-01784-4
Contributors: Ahmed H. El-Desoky; Yuki Hitora; Yoshitomo Nishime; Yusaku Sadahiro; Teppei Kawahara; Sachiko Tsukamoto
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Neopetromin, a Cyclic Tripeptide with a C–N Cross-Link, from the Marine Sponge Neopetrosia sp., That Causes Vacuole Fragmentation in Tobacco BY-2 Cells

Journal of Natural Products
2024-04-26 | Journal article
DOI: 10.1021/acs.jnatprod.4c00158
Contributors: Yuki Hitora; Ahmed H. El-Desoky; Yusaku Sadahiro; Ai Sejiyama; Amiri Kinoshita; Yuji Ise; Esther D. Angkouw; Remy E. P. Mangindaan; Takumi Higaki; Sachiko Tsukamoto
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Crossref

Syrosingopine Enhances 20S Proteasome Activity and Degradation of α-Synuclein

Journal of Natural Products
2024-03-22 | Journal article
DOI: 10.1021/acs.jnatprod.3c00661
Contributors: Yusaku Sadahiro; Soichiro Nishimura; Yuki Hitora; Sachiko Tsukamoto
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Aaptocarbamates A−G, chlorinated terpene carbamates with antiosteoclastogenic activities from the marine sponge Aaptos sp.

Phytochemistry
2023-12 | Journal article
DOI: 10.1016/j.phytochem.2023.113872
Contributors: Ahmed H. El-Desoky; Keisuke Eguchi; Ippei Kagiyama; Yuki Hitora; Hikaru Kato; Yuji Ise; Fitje Losung; Remy E.P. Mangindaan; Sachiko Tsukamoto
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Akanthomins A–C, aphidicolin analogs from a fungus Akanthomyces sp., that inhibit cell cycle

Phytochemistry
2023-12 | Journal article
DOI: 10.1016/j.phytochem.2023.113885
Contributors: Koyo Honda; Yuki Hitora; Sachiko Tsukamoto
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A monoacylglyceryltrimethylhomoserine, 21F121-A, containing a branched acyl group from Penicillium glaucoroseum

Journal of Natural Medicines
2023-09 | Journal article
DOI: 10.1007/s11418-023-01735-5
Contributors: Ichiro Kimura; Yuki Hitora; Yusaku Sadahiro; Teppei Kawahara; Sachiko Tsukamoto
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CyclosporinA Derivative as Therapeutic Candidate for Alport Syndrome by Inducing Mutant Type IV Collagen Secretion

Kidney360
2023-07 | Journal article
DOI: 10.34067/KID.0000000000000134
Contributors: Jun Kuwazuru; Mary Ann Suico; Kohei Omachi; Haruka Kojima; Misato Kamura; Shota Kaseda; Teppei Kawahara; Yuki Hitora; Hikaru Kato; Sachiko Tsukamoto et al.
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Arteperoxides A–C, tris-normonoterpene–sesquiterpene conjugates with peroxide-bridges from Artemisia judaica exhibiting antiosteoclastogenic activity

Phytochemistry
2023-02 | Journal article
DOI: 10.1016/j.phytochem.2022.113548
Contributors: Ahmed H. El-Desoky; Toshifumi Asano; Yuka Maeyama; Hikaru Kato; Yuki Hitora; Eishu Goto; Shunsuke Kotani; Makoto Nakajima; Sachiko Tsukamoto
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Divergent Total Syntheses of Hetero-Oligomeric Iridoid Glycosides

Organic Letters
2023-01-20 | Journal article
DOI: 10.1021/acs.orglett.2c03965
Contributors: Akiho Yoshidome; Jukiya Sakamoto; Mizuki Kohara; Shinya Shiomi; Mako Hokaguchi; Yuki Hitora; Mariko Kitajima; Sachiko Tsukamoto; Hayato Ishikawa
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Data Science-Driven Analysis of Substrate-Permissive Diketopiperazine Reverse Prenyltransferase NotF: Applications in Protein Engineering and Cascade Biocatalytic Synthesis of (−)-Eurotiumin A

Journal of the American Chemical Society
2022-10-26 | Journal article
DOI: 10.1021/jacs.2c06631
Contributors: Samantha P. Kelly; Vikram V. Shende; Autumn R. Flynn; Qingyun Dan; Ying Ye; Janet L. Smith; Sachiko Tsukamoto; Matthew S. Sigman; David H. Sherman
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Colletofragarone A2 Inhibits Cancer Cell Growth In Vivo and Leads to the Degradation and Aggregation of Mutant p53

Chemical Research in Toxicology
2022-09-19 | Journal article
DOI: 10.1021/acs.chemrestox.2c00202
Contributors: Yusaku Sadahiro; Yuki Hitora; Ichiro Kimura; Natsuko Hitora-Imamura; Risako Onodera; Keiichi Motoyama; Sachiko Tsukamoto
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Marine natural products that inhibit osteoclastogenesis and promote osteoblast differentiation

Journal of Natural Medicines
2022-06 | Journal article
DOI: 10.1007/s11418-022-01622-5
Contributors: Ahmed H. H. El-Desoky; Sachiko Tsukamoto
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Cell-based screening of extracts of natural sources to search for inhibitors of the ubiquitin–proteasome system and identification of proteasome inhibitors from the fungus Remotididymella sp.

Bioorganic & Medicinal Chemistry Letters
2022-03 | Journal article
DOI: 10.1016/j.bmcl.2022.128566
Contributors: Soichiro Nishimura; Yuki Hitora; Teppei Kawahara; Mika Tanabe; Eisuke Ogata; Hikaru Kato; Pattaravadee Srikoon; Takashi Watanabe; Sachiko Tsukamoto
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Colletofragarone A2 and Colletoins A–C from a Fungus Colletotrichum sp. Decrease Mutant p53 Levels in Cells

Journal of Natural Products
2021-12-24 | Journal article
DOI: 10.1021/acs.jnatprod.1c00913
Contributors: Yusaku Sadahiro; Yuki Hitora; Sachiko Tsukamoto
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Induction of secondary metabolite production by fungal co-culture of Talaromyces pinophilus and Paraphaeosphaeria sp.

Journal of Natural Medicines
2020-06-31 | Journal article
DOI: 10.1007/s11418-020-01400-1
Contributors: Shunya Murakami; Nozomu Hayashi; Teruyo Inomata; Hikaru Kato; Yuki Hitora; Sachiko Tsukamoto
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Melophluosides A and B, new triterpene galactosides from the marine sponge Melophlus sarasinorum

Tetrahedron Letters
2020-05 | Journal article
DOI: 10.1016/j.tetlet.2020.151852
Contributors: Yusaku Sadahiro; Yuki Hitora; Arina Fukumoto; Yuji Ise; Esther D. Angkouw; Remy E.P. Mangindaan; Sachiko Tsukamoto
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Irpexine, an Isoindolinone Alkaloid Produced by Coculture of Endophytic Fungi, Irpex lacteus and Phaeosphaeria oryzae

Journal of Natural Products
2020-05-22 | Journal article
DOI: 10.1021/acs.jnatprod.0c00047
Contributors: Yusaku Sadahiro; Hikaru Kato; Robert M. Williams; Sachiko Tsukamoto
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Nuciferols A and B: Novel sesquineolignans from Cocos nucifera

Tetrahedron Letters
2019-08 | Journal article
DOI: 10.1016/j.tetlet.2019.150948
Contributors: Marwa Elsbaey; Bai Jie; Chiaki Tanaka; Hikaru Kato; Sachiko Tsukamoto; Kazuteru Usui; Go Hirai; Tomofumi Miyamoto
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Taichunins A–D, Norditerpenes from Aspergillus taichungensis (IBT 19404)

Journal of Natural Products
2019-05-24 | Journal article
DOI: 10.1021/acs.jnatprod.8b01032
Contributors: Hikaru Kato; Momona Sebe; Mika Nagaki; Keisuke Eguchi; Ippei Kagiyama; Yuki Hitora; Jens C. Frisvad; Robert M. Williams; Sachiko Tsukamoto
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Halichonic acid, a new rearranged bisabolene-type sesquiterpene from a marine sponge Halichondria sp.

Tetrahedron Letters
2019-04 | Journal article
DOI: 10.1016/j.tetlet.2019.03.030
Contributors: Kenta Raiju; Yuki Hitora; Hikaru Kato; Yuji Ise; Esther D. Angkouw; Remy E.P. Mangindaan; Sachiko Tsukamoto
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Tetradehydrohalicyclamine B, a new proteasome inhibitor from the marine sponge Acanthostrongylophora ingens

Bioorganic & Medicinal Chemistry Letters
2019-01 | Journal article
DOI: 10.1016/j.bmcl.2018.11.028
Contributors: Hikaru Kato; Ahmed H. El-Desoky; Yuya Takeishi; Tatsuo Nehira; Esther D. Angkouw; Remy E.P. Mangindaan; Nicole J. de Voogd; Sachiko Tsukamoto
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Isolation of a new indoxyl alkaloid, Amoenamide B, from Aspergillus amoenus NRRL 35600: Biosynthetic implications and correction of the structure of Speramide B

Tetrahedron Letters
2018-11 | Journal article
DOI: 10.1016/j.tetlet.2018.10.034
Contributors: Aika Kai; Hikaru Kato; David H. Sherman; Robert M. Williams; Sachiko Tsukamoto
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Total syntheses and stereochemical reassignments of mollenines A and B

Bioorganic & Medicinal Chemistry Letters
2018-09 | Journal article
DOI: 10.1016/j.bmcl.2018.01.065
Contributors: Shinya Shiomi; Kohei Wada; Yuhei Umeda; Hikaru Kato; Sachiko Tsukamoto; Hayato Ishikawa
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New inhibitors of RANKL-induced Osteoclastogenesis from the marine sponge Siphonochalina siphonella

Fitoterapia
2018-07 | Journal article
DOI: 10.1016/j.fitote.2018.05.001
Contributors: Ahmed A. El-Beih; Ahmed H. El-Desoky; Montaser A. Al-hammady; Abdelsamed I. Elshamy; Mohamed-Elamir F. Hegazy; Hikaru Kato; Sachiko Tsukamoto
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Crossref

New geranyl flavonoids from the leaves of Artocarpus communis

Journal of Natural Medicines
2018-06-24 | Journal article
DOI: 10.1007/s11418-018-1192-z
Contributors: Masamitsu Inoue; Yuki Hitora; Hikaru Kato; Fitje Losung; Remy E. P. Mangindaan; Sachiko Tsukamoto
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Crossref

Total Synthesis and Biological Evaluation of Siladenoserinol A and its Analogues

Angewandte Chemie International Edition
2018-04-23 | Journal article
DOI: 10.1002/anie.201801659
Contributors: Masahito Yoshida; Koya Saito; Hikaru Kato; Sachiko Tsukamoto; Takayuki Doi
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Crossref

Total Synthesis and Biological Evaluation of Siladenoserinol A and its Analogues

Angewandte Chemie
2018-04-23 | Journal article
DOI: 10.1002/ange.201801659
Contributors: Masahito Yoshida; Koya Saito; Hikaru Kato; Sachiko Tsukamoto; Takayuki Doi
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Crossref

Identification of the Biosynthetic Gene Cluster for Himeic Acid A: A Ubiquitin‐Activating Enzyme (E1) Inhibitor in Aspergillus japonicus MF275

ChemBioChem
2018-03-16 | Journal article
DOI: 10.1002/cbic.201700584
Contributors: Makoto Hashimoto; Hikaru Kato; Ayako Katsuki; Sachiko Tsukamoto; Isao Fujii
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Correction to “Isolation of Notoamide S and Enantiomeric 6-epi-Stephacidin A from the Terrestrial Fungus Aspergillus amoenus: Biogenetic Implications”

Organic Letters
2018-01-05 | Journal article
DOI: 10.1021/acs.orglett.7b03781
Contributors: Hikaru Kato; Takashi Nakahara; Kayo Sugimoto; Kanae Matsuo; Ippei Kagiyama; Jens C. Frisvad; David H. Sherman; Robert M. Williams; Sachiko Tsukamoto
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Enantioselective inhibitory abilities of enantiomers of notoamides against RANKL-induced formation of multinuclear osteoclasts

Bioorganic & Medicinal Chemistry Letters
2017-11 | Journal article
DOI: 10.1016/j.bmcl.2017.10.017
Contributors: Hikaru Kato; Aika Kai; Tetsuro Kawabata; James D. Sunderhaus; Timothy J. McAfoos; Jennifer M. Finefield; Yukihiko Sugimoto; Robert M. Williams; Sachiko Tsukamoto
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Crossref

Ceylonins G–I: spongian diterpenes from the marine sponge Spongia ceylonensis

Journal of Natural Medicines
2017-10-03 | Journal article
DOI: 10.1007/s11418-017-1087-4
Contributors: Ahmed H. El-Desoky; Hikaru Kato; Sachiko Tsukamoto
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Lamellodysidines A and B, Sesquiterpenes Isolated from the Marine Sponge Lamellodysidea herbacea

Journal of Natural Products
2017-09-22 | Journal article
DOI: 10.1021/acs.jnatprod.7b00610
Contributors: Masumi Torii; Hikaru Kato; Yuki Hitora; Esther D. Angkouw; Remy E. P. Mangindaan; Nicole J. de Voogd; Sachiko Tsukamoto
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Isolation of amoenamide A and five antipodal prenylated alkaloids from Aspergillus amoenus NRRL 35600

Tetrahedron Letters
2017-07 | Journal article
DOI: 10.1016/j.tetlet.2017.05.057
Contributors: Kayo Sugimoto; Yusaku Sadahiro; Ippei Kagiyama; Hikaru Kato; David H. Sherman; Robert M. Williams; Sachiko Tsukamoto
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Crossref

Sulawesins A–C, Furanosesterterpene Tetronic Acids That Inhibit USP7, from a Psammocinia sp. Marine Sponge

Journal of Natural Products
2017-07-28 | Journal article
DOI: 10.1021/acs.jnatprod.7b00184
Contributors: Ahmed H. Afifi; Ippei Kagiyama; Ahmed H. El-Desoky; Hikaru Kato; Remy E. P. Mangindaan; Nicole J. de Voogd; Nagwa M. Ammar; Mohammed S. Hifnawy; Sachiko Tsukamoto
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Crossref

Ceylonins A–F, Spongian Diterpene Derivatives That Inhibit RANKL-Induced Formation of Multinuclear Osteoclasts, from the Marine Sponge Spongia ceylonensis

Journal of Natural Products
2017-01-27 | Journal article
DOI: 10.1021/acs.jnatprod.6b00725
Contributors: Ahmed H. El-Desoky; Hikaru Kato; Ippei Kagiyama; Yuki Hitora; Fitje Losung; Remy E. P. Mangindaan; Nicole J. de Voogd; Sachiko Tsukamoto
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Ceylonamides A-F, Nitrogenous Spongian Diterpenes That Inhibit RANKL-Induced Osteoclastogenesis, from the Marine Sponge Spongia ceylonensis

Journal of Natural Products
2016 | Journal article
DOI: 10.1021/acs.jnatprod.6b00158
EID:

2-s2.0-84984801410
Contributors: El-Desoky, A.H.; Kato, H.; Angkouw, E.D.; Mangindaan, R.E.P.; De Voogd, N.J.; Tsukamoto, S.
Source: Self-asserted source
Sachiko Tsukamoto via Scopus - Elsevier

Collective synthesis and biological evaluation of tryptophan-based dimeric diketopiperazine alkaloids

Chemistry - A European Journal
2016 | Journal article
DOI: 10.1002/chem.201503417
EID:

2-s2.0-84954398052
Contributors: Tadano, S.; Sugimachi, Y.; Sumimoto, M.; Tsukamoto, S.; Ishikawa, H.
Source: Self-asserted source
Sachiko Tsukamoto via Scopus - Elsevier

Foreword

Chemical and Pharmaceutical Bulletin
2016 | Journal article
EID:

2-s2.0-84958206598
Contributors: Tsukamoto, S.
Source: Self-asserted source
Sachiko Tsukamoto via Scopus - Elsevier

Petroquinones: trimeric and dimeric xestoquinone derivatives isolated from the marine sponge Petrosia alfiani

Tetrahedron
2016 | Journal article
DOI: 10.1016/j.tet.2016.07.045
EID:

2-s2.0-84979881242
Contributors: Tanokashira, N.; Kukita, S.; Kato, H.; Nehira, T.; Angkouw, E.D.; Mangindaan, R.E.P.; de Voogd, N.J.; Tsukamoto, S.
Source: Self-asserted source
Sachiko Tsukamoto via Scopus - Elsevier

Search for inhibitors of the ubiquitin-proteasome system from natural sources for cancer therapy

Chemical and Pharmaceutical Bulletin
2016 | Journal article
EID:

2-s2.0-84958156968
Contributors: Tsukamoto, S.
Source: Self-asserted source
Sachiko Tsukamoto via Scopus - Elsevier

Taichunamides: Prenylated indole alkaloids from Aspergillus taichungensis (IBT 19404)

Angewandte Chemie - International Edition
2016 | Journal article
DOI: 10.1002/anie.201509462
EID:

2-s2.0-84954305650
Contributors: Kagiyama, I.; Kato, H.; Nehira, T.; Frisvad, J.C.; Sherman, D.H.; Williams, R.M.; Tsukamoto, S.
Source: Self-asserted source
Sachiko Tsukamoto via Scopus - Elsevier

Bastadins, brominated-tyrosine derivatives, suppress accumulation of cholesterol ester in macrophages

Bioorganic and Medicinal Chemistry Letters
2015 | Journal article
DOI: 10.1016/j.bmcl.2015.09.024
EID:

2-s2.0-84945904798
Contributors: Eguchi, K.; Kato, H.; Fujiwara, Y.; Losung, F.; Mangindaan, R.E.P.; De Voogd, N.J.; Takeya, M.; Tsukamoto, S.
Source: Self-asserted source
Sachiko Tsukamoto via Scopus - Elsevier

Bioconversion of 6-epi-Notoamide T produces metabolites of unprecedented structures in a marine-derived Aspergillus sp.

Tetrahedron Letters
2015 | Journal article
DOI: 10.1016/j.tetlet.2014.11.083
EID:

2-s2.0-84918560106
Contributors: Kato, H.; Nakahara, T.; Yamaguchi, M.; Kagiyama, I.; Finefield, J.M.; Sunderhaus, J.D.; Sherman, D.H.; Williams, R.M.; Tsukamoto, S.
Source: Self-asserted source
Sachiko Tsukamoto via Scopus - Elsevier

Carteritins A and B, cyclic heptapeptides from the marine sponge Stylissa carteri

Tetrahedron Letters
2015 | Journal article
DOI: 10.1016/j.tetlet.2016.02.031
EID:

2-s2.0-84968378031
Contributors: Afifi, A.H.; El-Desoky, A.H.; Kato, H.; Mangindaan, R.E.P.; de Voogd, N.J.; Ammar, N.M.; Hifnawy, M.S.; Tsukamoto, S.
Source: Self-asserted source
Sachiko Tsukamoto via Scopus - Elsevier

Comment on "asymmetric syntheses of sceptrin and massadine and evidence for biosynthetic enantiodivergence"

Science
2015 | Journal article
DOI: 10.1126/science.aaa9349
EID:

2-s2.0-84937544453
Contributors: Sherman, D.H.; Tsukamoto, S.; Williams, R.M.
Source: Self-asserted source
Sachiko Tsukamoto via Scopus - Elsevier

Inhibitors for cholesterol ester accumulation in macrophages from Chinese cabbage

Bioscience, Biotechnology and Biochemistry
2015 | Journal article
DOI: 10.1080/09168451.2015.1023247
EID:

2-s2.0-84942234228
Contributors: Takamoto, H.; Eguchi, K.; Kawabata, T.; Fujiwara, Y.; Takeya, M.; Tsukamoto, S.
Source: Self-asserted source
Sachiko Tsukamoto via Scopus - Elsevier

Isolation of notoamide S and enantiomeric 6- epi -stephacidin a from the fungus aspergillus amoenus: Biogenetic implications

Organic Letters
2015 | Journal article
DOI: 10.1021/ol5037198
EID:

2-s2.0-84922641436
Contributors: Kato, H.; Nakahara, T.; Sugimoto, K.; Matsuo, K.; Kagiyama, I.; Frisvad, J.C.; Sherman, D.H.; Williams, R.M.; Tsukamoto, S.
Source: Self-asserted source
Sachiko Tsukamoto via Scopus - Elsevier

Manadodioxans A-E: Polyketide endoperoxides from the marine sponge Plakortis bergquistae

Journal of Natural Medicines
2015 | Journal article
DOI: 10.1007/s11418-015-0920-x
EID:

2-s2.0-84941261011
Contributors: Gushiken, M.; Kagiyama, I.; Kato, H.; Kuwana, T.; Losung, F.; Mangindaan, R.E.P.; De Voogd, N.J.; Tsukamoto, S.
Source: Self-asserted source
Sachiko Tsukamoto via Scopus - Elsevier
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Peer review (63 reviews for 11 publications/grants)

Review activity for ACS omega. (1)
Review activity for Bioorganic & medicinal chemistry letters. (1)
Review activity for ChemBioChem. (1)
Review activity for Fitoterapia. (1)
Review activity for Journal of agricultural and food chemistry. (2)
Review activity for Journal of medicinal chemistry. (2)
Review activity for Journal of natural products. (27)
Review activity for Journal of organic chemistry. (19)
Review activity for Organic letters. (5)
Review activity for Tetrahedron letters. (2)
Review activity for Tetrahedron. (2)
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