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Funding (3)

Integrated ImageXpress Micro Confocal High Content Screening System

2021-06-15 to 2022-05-31 | Grant
Office of the Director (Bethesda, US)
URL: https://app.dimensions.ai/details/grant/grant.9734541
GRANT_NUMBER: S10OD028719
Source: Self-asserted source
Joshua Bauer via DimensionsWizard

Cancer Pharmacologist and HTS Scientist

2016-09-19 to 2026-08-31 | Grant
National Cancer Institute (Bethesda, US)
URL: https://app.dimensions.ai/details/grant/grant.6443240
GRANT_NUMBER: R50CA211206
Source: Self-asserted source
Joshua Bauer via DimensionsWizard

Identification of druggable targets for triple-negative breast cancer

2009-03-01 to 2010-02-28 | Grant
National Cancer Institute (Bethesda, US)
URL: https://app.dimensions.ai/details/grant/grant.2373380
GRANT_NUMBER: F32CA138106
Source: Self-asserted source
Joshua Bauer via DimensionsWizard

Works (43)

Refining breast cancer genetic risk and biology through multi-ancestry fine-mapping analyses of 192 risk regions

Nature Genetics
2025-01 | Journal article
DOI: 10.1038/s41588-024-02031-y
Contributors: Guochong Jia; Zhishan Chen; Jie Ping; Qiuyin Cai; Ran Tao; Chao Li; Joshua A. Bauer; Yuhan Xie; Stefan Ambs; Mollie E. Barnard et al.
Source: check_circle
Crossref

A High-Throughput Immune-Oncology Screen Identifies Immunostimulatory Properties of Cytotoxic Chemotherapy Agents in TNBC

Cancers
2024-12-05 | Journal article
DOI: 10.3390/cancers16234075
Contributors: Kennady K. Bullock; Thomas Hasaka; Emily Days; Joshua A. Bauer; Patricia A. Ward; Ann Richmond
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

A High-Throughput Immune-Oncology Screen Identifies Immunostimulatory Properties of Cytotoxic Chemotherapy Agents in TNBC

2024-11-08 | Preprint
DOI: 10.20944/preprints202411.0535.v1
Contributors: Kennady K Bullock; Thomas P Hasaka; Emily Days; Joshua A Bauer; Patricia A Ward; Ann Richmond
Source: check_circle
Crossref

Small-Molecule Modulators of Lipid Raft Stability and Protein-Raft Partitioning

2024-10-31 | Preprint
DOI: 10.1101/2024.10.28.620521
Contributors: Katherine M. Stefanski; Hui Huang; Dustin D. Luu; James M. Hutchison; Nilabh Saksena; Alexander J. Fisch; Thomas P. Hasaka; Joshua A. Bauer; Anne K. Kenworthy; Wade D. Van Horn et al.
Source: check_circle
Crossref

Combined Dusp4 and p53 loss with Dbf4 amplification drives tumorigenesis via cell cycle restriction and replication stress escape in breast cancer.

Breast cancer research : BCR
2022-07-18 | Journal article
DOI: 10.1186/s13058-022-01542-y
PMID: 35850776
PMC: PMC9290202
Source: Self-asserted source
Joshua Bauer

Screen for Small-Molecule Modulators of Circadian Rhythms Reveals Phenazine as a Redox-State Modifying Clockwork Tuner.

ACS chemical biology
2022-06-09 | Journal article
DOI: 10.1021/acschembio.2c00240
PMID: 35679588
Source: Self-asserted source
Joshua Bauer

Utilizing Three-Dimensional Culture Methods to Improve High-Throughput Drug Screening in Anaplastic Thyroid Carcinoma

Cancers
2022-04 | Journal article | Author
DOI: 10.3390/cancers14081855
Contributors: Kensey Bergdorf; Joshua Bauer; David Westover; Courtney Phifer; Barbara Murphy; Darren Tyson; Ethan Lee; Vivian Weiss
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

VU6036720: The First Potent and Selective In Vitro Inhibitor of Heteromeric Kir4.1/5.1 Inward Rectifier Potassium Channels.

Molecular pharmacology
2022-03-03 | Journal article
DOI: 10.1124/molpharm.121.000464
PMID: 35246480
Source: Self-asserted source
Joshua Bauer

High-Content Imaging Platform to Discover Chemical Modulators of Plasma Membrane Rafts.

ACS central science
2022-02-21 | Journal article
DOI: 10.1021/acscentsci.1c01058
PMID: 35355811
PMC: PMC8961798
Source: Self-asserted source
Joshua Bauer

TBX1 functions as a putative oncogene of breast cancer through promoting cell cycle progression.

Carcinogenesis
2022-02-01 | Journal article
DOI: 10.1093/carcin/bgab111
PMID: 34919666
Source: Self-asserted source
Joshua Bauer

Functional Genomic Analyses of the 21q22.3 Locus Identifying Functional Variants and Candidate Gene YBEY for Breast Cancer Risk

Cancers
2021-04-23 | Journal article
DOI: 10.3390/cancers13092037
Contributors: Chris Shidal; Xiang Shu; Jie Wu; Jifeng Wang; Shuya Huang; Jirong Long; Joshua A. Bauer; Jie Ping; Xingyi Guo; Wei Zheng et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

High-throughput drug screening of fine-needle aspiration-derived cancer organoids.

STAR protocols
2020-12-16 | Journal article
DOI: 10.1016/j.xpro.2020.100212
PMID: 33377106
PMC: PMC7757655
Source: Self-asserted source
Joshua Bauer

Fine-Needle Aspiration-Based Patient-Derived Cancer Organoids.

iScience
2020-07-24 | Journal article
DOI: 10.1016/j.isci.2020.101408
PMID: 32771978
PMC: PMC7415927
Source: Self-asserted source
Joshua Bauer

Targeting MYCN-expressing triple-negative breast cancer with BET and MEK inhibitors.

Science translational medicine
2020-03-01 | Journal article
DOI: 10.1126/scitranslmed.aaw8275
PMID: 32161105
PMC: PMC7427123
Source: Self-asserted source
Joshua Bauer

Novel three-dimensional cultures provide insights into thyroid cancer behavior.

Endocrine-related cancer
2020-02-01 | Journal article
DOI: 10.1530/erc-19-0374
PMID: 31804972
PMC: PMC7295136
Source: Self-asserted source
Joshua Bauer

Discovery and Optimization of Salicylic Acid-Derived Sulfonamide Inhibitors of the WD Repeat-Containing Protein 5-MYC Protein-Protein Interaction.

Journal of medicinal chemistry
2019-12-05 | Journal article
DOI: 10.1021/acs.jmedchem.9b01411
PMID: 31724864
PMC: PMC6933084
Source: Self-asserted source
Joshua Bauer

Aberrant FGFR signaling mediates resistance to CDK4/6 inhibitors in ER+ breast cancer.

Nature communications
2019-03-26 | Journal article
DOI: 10.1038/s41467-019-09068-2
PMID: 30914635
PMC: PMC6435685
Source: Self-asserted source
Joshua Bauer

Quantifying Drug Combination Synergy along Potency and Efficacy Axes.

Cell systems
2019-02-20 | Journal article
DOI: 10.1016/j.cels.2019.01.003
PMID: 30797775
PMC: PMC6675406
Source: Self-asserted source
Joshua Bauer

Dual inhibition of Kif15 by oxindole and quinazolinedione chemical probes.

Bioorganic & medicinal chemistry letters
2018-12-04 | Journal article
DOI: 10.1016/j.bmcl.2018.12.008
PMID: 30528696
PMC: PMC6681659
Source: Self-asserted source
Joshua Bauer

The TRiC chaperonin controls reovirus replication through outer-capsid folding.

Nature microbiology
2018-03-12 | Journal article
DOI: 10.1038/s41564-018-0122-x
PMID: 29531365
PMC: PMC5874176
Source: Self-asserted source
Joshua Bauer

Corrigendum to "Comparative Study of Exome Copy Number Variation Estimation Tools Using Array Comparative Genomic Hybridization as Control".

BioMed research international
2017-07-18 | Journal article
DOI: 10.1155/2017/7409598
PMID: 28804721
PMC: PMC5540237
Source: Self-asserted source
Joshua Bauer
grade
Preferred source (of 2)‎

SFK/FAK Signaling Attenuates Osimertinib Efficacy in Both Drug-Sensitive and Drug-Resistant Models of EGFR-Mutant Lung Cancer.

Cancer research
2017-04-17 | Journal article
DOI: 10.1158/0008-5472.can-16-2300
PMID: 28416483
PMC: PMC5467531
Source: Self-asserted source
Joshua Bauer

Kinome-Wide RNA Interference Screen Reveals a Role for PDK1 in Acquired Resistance to CDK4/6 Inhibition in ER-Positive Breast Cancer.

Cancer research
2017-03-01 | Journal article
DOI: 10.1158/0008-5472.can-16-2653
PMID: 28249908
PMC: PMC5421398
Source: Self-asserted source
Joshua Bauer

Antagonism of the Sodium-Potassium ATPase Impairs Chikungunya Virus Infection.

mBio
2016-05-24 | Journal article
DOI: 10.1128/mbio.00693-16
PMID: 27222471
PMC: PMC4895112
Source: Self-asserted source
Joshua Bauer

Cellular manganese content is developmentally regulated in human dopaminergic neurons.

Scientific reports
2014-10-28 | Journal article
DOI: 10.1038/srep06801
PMID: 25348053
PMC: PMC4210885
Source: Self-asserted source
Joshua Bauer

PIK3CA mutations in androgen receptor-positive triple negative breast cancer confer sensitivity to the combination of PI3K and androgen receptor inhibitors.

Breast cancer research : BCR
2014-08-08 | Journal article
DOI: 10.1186/s13058-014-0406-x
PMID: 25103565
PMC: PMC4187324
Source: Self-asserted source
Joshua Bauer

Molecular profiling of the residual disease of triple-negative breast cancers after neoadjuvant chemotherapy identifies actionable therapeutic targets.

Cancer discovery
2013-12-19 | Journal article
DOI: 10.1158/2159-8290.cd-13-0286
PMID: 24356096
PMC: PMC3946308
Source: Self-asserted source
Joshua Bauer

Comparative study of exome copy number variation estimation tools using array comparative genomic hybridization as control.

BioMed research international
2013-11-04 | Journal article
DOI: 10.1155/2013/915636
PMID: 24303503
PMC: PMC3835197
Source: Self-asserted source
Joshua Bauer

A novel reporter system for molecular imaging and high-throughput screening of anticancer drugs.

Chembiochem : a European journal of chemical biology
2013-07-24 | Journal article
DOI: 10.1002/cbic.201300142
PMID: 23881799
PMC: PMC3819221
Source: Self-asserted source
Joshua Bauer

Analysis of high-throughput RNAi screening data in identifying genes mediating sensitivity to chemotherapeutic drugs: statistical approaches and perspectives.

BMC genomics
2012-12-17 | Journal article
DOI: 10.1186/1471-2164-13-s8-s3
PMID: 23281588
PMC: PMC3535706
Source: Self-asserted source
Joshua Bauer

TNBCtype: A Subtyping Tool for Triple-Negative Breast Cancer.

Cancer informatics
2012-07-24 | Journal article
DOI: 10.4137/cin.s9983
PMID: 22872785
PMC: PMC3412597
Source: Self-asserted source
Joshua Bauer

Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies.

The Journal of clinical investigation
2011-07-01 | Journal article
DOI: 10.1172/jci45014
PMID: 21633166
PMC: PMC3127435
Source: Self-asserted source
Joshua Bauer

Preoperative concurrent paclitaxel-radiation in locally advanced breast cancer: pathologic response correlates with five-year overall survival.

Breast cancer research and treatment
2010-09-29 | Journal article
DOI: 10.1007/s10549-010-1181-8
PMID: 20878462
PMC: PMC3655407
Source: Self-asserted source
Joshua Bauer

RNA interference (RNAi) screening approach identifies agents that enhance paclitaxel activity in breast cancer cells.

Breast cancer research : BCR
2010-06-24 | Journal article
DOI: 10.1186/bcr2595
PMID: 20576088
PMC: PMC2917036
Source: Self-asserted source
Joshua Bauer

Identification of markers of taxane sensitivity using proteomic and genomic analyses of breast tumors from patients receiving neoadjuvant paclitaxel and radiation.

Clinical cancer research : an official journal of the American Association for Cancer Research
2010-01-12 | Journal article
DOI: 10.1158/1078-0432.ccr-09-1091
PMID: 20068102
PMC: PMC2892225
Source: Self-asserted source
Joshua Bauer

Reactivation of p53 by a specific MDM2 antagonist (MI-43) leads to p21-mediated cell cycle arrest and selective cell death in colon cancer.

Molecular cancer therapeutics
2008-06-01 | Journal article
DOI: 10.1158/1535-7163.mct-08-0140
PMID: 18566224
PMC: PMC2494594
Source: Self-asserted source
Joshua Bauer

Anti-oxidant treatment enhances anti-tumor cytotoxicity of (-)-gossypol.

Cancer biology & therapy
2008-05-20 | Journal article
DOI: 10.4161/cbt.7.5.5767
PMID: 18376141
PMC: PMC4157391
Source: Self-asserted source
Joshua Bauer

EGFR, p16, HPV Titer, Bcl-xL and p53, sex, and smoking as indicators of response to therapy and survival in oropharyngeal cancer.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology
2008-05-12 | Journal article
DOI: 10.1200/jco.2007.12.7662
PMID: 18474878
PMC: PMC2744895
Source: Self-asserted source
Joshua Bauer

Targeting apoptosis to overcome cisplatin resistance: a translational study in head and neck cancer.

International journal of radiation oncology, biology, physics
2007-01-01 | Journal article
DOI: 10.1016/j.ijrobp.2007.05.080
PMID: 17848273
PMC: PMC2064007
Source: Self-asserted source
Joshua Bauer

A novel BH3 mimetic reveals a mitogen-activated protein kinase-dependent mechanism of melanoma cell death controlled by p53 and reactive oxygen species.

Cancer research
2006-12-01 | Journal article
DOI: 10.1158/0008-5472.can-06-1748
PMID: 17145881
Source: Self-asserted source
Joshua Bauer

Reversal of cisplatin resistance with a BH3 mimetic, (-)-gossypol, in head and neck cancer cells: role of wild-type p53 and Bcl-xL.

Molecular cancer therapeutics
2005-07-01 | Journal article
DOI: 10.1158/1535-7163.mct-05-0081
PMID: 16020667
Source: Self-asserted source
Joshua Bauer

In vitro effects of the BH3 mimetic, (-)-gossypol, on head and neck squamous cell carcinoma cells.

Clinical cancer research : an official journal of the American Association for Cancer Research
2004-11-01 | Journal article
DOI: 10.1158/1078-0432.ccr-04-0551
PMID: 15570010
Source: Self-asserted source
Joshua Bauer

Growth inhibition and differentiation in human prostate carcinoma cells induced by the vitamin D analog 1alpha,24-dihydroxyvitamin D2.

The Prostate
2003-05-01 | Journal article
DOI: 10.1002/pros.10219
PMID: 12692781
Source: Self-asserted source
Joshua Bauer

Peer review (2 reviews for 2 publications/grants)

Review activity for Nature communications (1)
Review activity for SLAS discovery. (1)
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