Personal information

Switzerland

Biography

Jean-François Dufour studied mathematics at the University of Geneva, Switzerland, and received his medical degree from the Geneva Medical School. After training in internal medicine at the University Hospital Geneva and the University Hospital Bern, he joined the laboratory of Professor I. Arias at Tufts University in Boston, Massachusetts, USA where he studied the effects of calcium signalling on bile canaliculus. He then returned to the clinic to complete a gastroenterology fellowship with Professor M. Kaplan at the New England Medical Center, also at Tufts University. In 1997, Professor Dufour established his own laboratory at the University of Bern. He was Clinic Director and Full Professor of Hepatology frtom 2011 to 2021. He transformed the Liver Unit to a national and internationally center of excellence for liver diseases. He is now director of the Centre des Maladies Digestives in Lausanne. Professor Dufour is member of the AASLD, AGA, EASL, ACG, the Swiss Association for the Study of the Liver, and the Schweizerische Gesellschaft für Gastroenterologie und Hepatologie. He is a founding member of the International Liver Cancer Association. He was twice member of the Governing Board of EASL as a Scientific Committee Member and then as Educational Councillor. He was also a member of the UEG Educational Committee. Professor Dufour has a broad understanding of basic, translational and clinical research, its bottlenecks and the challenges in disseminating and exploiting knowledge. Professor Dufour has served as the principal investigator on multiple clinical studies, focusing on NASH and HCC. His laboratory explores the link between fatty liver, physical activity and liver cancer. He was/is an Associate Editor of the Journal of Hepatology, Hepatology (section Highlights), GUT, Liver International and Clinical Sciences. Professor Dufour has published more than 300 peer-reviewed publications.

Activities

Employment (1)

Insel Gruppe AG: Bern, Bern, CH

2011-03-01 to 2021-02-28 | Clinic Director UVCM Hepatology / Head Physician Hepatology (University Clinic for Visceral Surgery and Medicine / Hepatology)
Employment
Source: Self-asserted source
Jean-François Dufour

Education and qualifications (2)

University of Geneva: Geneva, Geneva, CH

1979 to 1986 | Medical School
Education
Source: Self-asserted source
Jean-François Dufour

University Geneva: Geneva, Geneva, CH

1979 to 1984 | Mathematical studies:
Education
Source: Self-asserted source
Jean-François Dufour

Professional activities (8)

STAL Arbeitsgruppe Lebertransplantation von Swisstransplant: Bern, CH

Membership
Source: Self-asserted source
Jean-François Dufour

Schweizerische Gesellschaft für Zellbiologie, Molekularbiologie und Genetik: Basel, CH

Membership
Source: Self-asserted source
Jean-François Dufour

Schweizerische Gesellschaft für Gastroenterologie und Hepatologie : Bern, CH

Membership
Source: Self-asserted source
Jean-François Dufour

ILCA International Liver Cancer Association: Brussels, BE

founding member
Membership
Source: Self-asserted source
Jean-François Dufour

European Association for the Study of the Liver: Geneve, GE, CH

Membership
Source: Self-asserted source
Jean-François Dufour

American College of Gastroenterology: Md., Md., US

Fellow
Membership
Source: Self-asserted source
Jean-François Dufour

American College of Gastroenterology: Md., Md., US

Membership
Source: Self-asserted source
Jean-François Dufour

American Association for the Study of Liver Diseases: Alexandria, VA, US

Fellow
Membership
Source: Self-asserted source
Jean-François Dufour

Funding (16)

Liver Investigation: Testing Marker Utility in Steatohepatitis

2017 to 2019 | Grant
LITMUS (Newcastle, GB)
Source: Self-asserted source
Jean-François Dufour

Metabolic control of hepatocytes proliferation in regeneration and cancer

2016 to 2018 | Grant
Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (Bern, CH)
Source: Self-asserted source
Jean-François Dufour

Hint2 and nutritional stress

2015 to 2018 | Grant
Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (Bern, CH)
Source: Self-asserted source
Jean-François Dufour

How physical activity influences carcinogenesis: the case of HCC

2015 to 2018 | Grant
Swiss Cancer Research (Bern, CH)
Source: Self-asserted source
Jean-François Dufour

Nitric oxide in hepatocellular carcinoma: mechanistic and therapeutic implications

2015 to 2017 | Grant
Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (Bern, CH)
Source: Self-asserted source
Jean-François Dufour

Metabolic pathways governing liver carcinogenesis and regeneration

2013 to 2015 | Grant
Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (Bern, CH)
Source: Self-asserted source
Jean-François Dufour

Hint proteins a closer look

2012 to 2015 | Grant
Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (Bern, CH)
Source: Self-asserted source
Jean-François Dufour

FP7-HEALTH-2009-single-stage, Proposal No: 241762. Fatty liver: Inhibition of progression (FLIP)

2009 to 2009 | Contract
FLIP - Fatty Liver Inhibition of Progression (Paris, FR)
GRANT_NUMBER: 241762
Source: Self-asserted source
Jean-François Dufour

Hint1, Hint2, apoptosis and cell proliferation

2009 to 2009 | Grant
Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (Bern, CH)
Source: Self-asserted source
Jean-François Dufour

Studying the effect of mTOR inhibitor and sunitinib on hepatic stellate cells

2009 to 2009 | Grant
Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (Bern, CH)
Source: Self-asserted source
Jean-François Dufour

The link between aberrant MET signaling and DNA repair pathways in liver tumor cells as a target for sensitization to DNA damaging agents

2009 to 2009 | Grant
Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (Bern, CH)
Source: Self-asserted source
Jean-François Dufour

Hint2, a mitochondrial tumor suppressor

2006 to 2006 | Grant
Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (Bern, CH)
Source: Self-asserted source
Jean-François Dufour

Swiss Hepatitis C Cohort Study

2006 to 2006 | Grant
Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (Bern, CH)
Source: Self-asserted source
Jean-François Dufour

Ion-selective microelectrode array for the detection of intracellular calcium activities

2004 to 2004 | Grant
Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (Bern, CH)
Source: Self-asserted source
Jean-François Dufour

Systemic gene therapy of hepatocellular carcinoma by tumor restricted, self-limited E2F-1 overexpression from the hTERT promoter

2004 to 2004 | Grant
Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (Bern, CH)
Source: Self-asserted source
Jean-François Dufour

Hint2, a new Hint protein

2003 to 2003 | Grant
Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (Bern, CH)
Source: Self-asserted source
Jean-François Dufour

Peer review (1 review for 1 publication/grant)

Review activity for Nature reviews. (1)