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Activities

Employment (1)

Tianjin Medical University: Tianjin, CN

Professor
Employment
Source: Self-asserted source
Hui Shen

Education and qualifications (3)

Wuhan University: Wuhan, CN

1996-09-01 to 1999-07-15 | Ph.D. (Dept. of Internal Medicine, Wuhan University Renmin Hospital)
Education
Source: Self-asserted source
Hui Shen

Hubei Medical University: Wuhan, Hubei, CN

1985-09-01 to 1988-07-14 | Master's Degree (Dept. of Pathophysiology)
Education
Source: Self-asserted source
Hui Shen

Hubei College of Science and Technology: Xiannin, Hubei, CN

1980-09-01 to 1985-07-15 | M.D (School of Medicine)
Education
Source: Self-asserted source
Hui Shen

Professional activities (6)

Society for Neuroscience of China: Beijing, CN

2013-09-09 to present | Member
Membership
Source: Self-asserted source
Hui Shen

Society for Neuroscience: Washington, D.C., US

2001-10-10 to 2015-05-09 | Member
Membership
Source: Self-asserted source
Hui Shen

SUNY Downstate Medical Center: Brooklyn, US

2001-07-30 to 2013-06-14 | Research Associate Professor (Dept. of Physiology & Pharmacology)
Service
Source: Self-asserted source
Hui Shen

University of Toronto: Toronto, CA

1999-12-04 to 2001-07-29 | Post-doctoral fellow (Western Research Institute)
Service
Source: Self-asserted source
Hui Shen

Renmin Hospital of Wuhan University: Wuhan, CN

1999-07-15 to 1999-12-03 | Associate Professor (Dept. of Internal Medicine)
Service
Source: Self-asserted source
Hui Shen

Wuhan First Hospital: Wuhan, Hubei, CN

1988-08-14 to 1996-08-31 | Attending Doctor (Dept. of Internal Medicine)
Service
Source: Self-asserted source
Hui Shen

Works (46)

Unlocking potential of oxytocin: improving intracranial lymphatic drainage for Alzheimer's disease treatment

Theranostics
2024 | Journal article
Contributors: Hui Shen
Source: Self-asserted source
Hui Shen

Sex differences in motor learning flexibility are accompanied by sex differences in mushroom spine pruning of the mouse primary motor cortex during adolescence

Front Neurosci
2024-07 | Journal article
Contributors: Hui Shen
Source: Self-asserted source
Hui Shen

L-DOPA ameliorates hippocampus-based mitochondria respiratory dysfunction caused by GCI/R injury

Biomed Pharmacother
2024-06 | Journal article
Contributors: Hui Shen
Source: Self-asserted source
Hui Shen

Prophylactic Effects of n-Acethylcysteine on Inflammation-induced Depression-like Behaviors in Mice

Neuroscience
2024-05-08 | Journal article
Contributors: Hui Shen
Source: Self-asserted source
Hui Shen

Regulation of specific abnormal calcium signals in the hippocampal CA1 and primary cortex M1 alleviates the progression of temporal lobe epilepsy.

Neural Regen Res
2023-07 | Journal article
Contributors: Hui Shen
Source: Self-asserted source
Hui Shen

Neuropathic pain following spinal cord hemisection induced by the reorganization in primary somatosensory cortex and regulated by neuronal activity of lateral parabrachial nucleus

CNS Neuroscience & Therapeutics
2023-04 | Journal article
Contributors: Hui Shen
Source: Self-asserted source
Hui Shen

Carrier-free quercetin nanomedicine blocks NLRP3 deubiquitination and TXNIP recruitment for Parkinson’s disease therapy

Chemical Engineering Journal
2023-03 | Journal article
Contributors: Hui Shen
Source: Self-asserted source
Hui Shen

Forkhead Box i2 Transcription Factor Regulates Systemic Energy Metabolism Via Neuropeptide AgRP

Diabetes
2022-10 | Journal article
Contributors: Hui Shen
Source: Self-asserted source
Hui Shen

Theoretical design of ultracompact three-dimensional isotropic two-photon 4Pi STED microscopy based on multifunctional metalenses focusing system

Journal of Physics D: Applied Physics
2022-07-28 | Journal article | Author
Part of ISSN: 0022-3727
Part of ISSN: 1361-6463
Contributors: Yang Li; Shihu Zhao; Dandan Ju; Mingyan Luo; Dongming Xiu; shujing liu; Hui Shen
Source: Self-asserted source
Hui Shen

Effects of sleep deprivation of various durations on novelty-related object recognition memory and object location memory in mice.

Behav Brain Res
2022-04-10 | Journal article
Contributors: Hui Shen
Source: Self-asserted source
Hui Shen

Preventing adolescent synaptic pruning in mouse prelimbic cortex via local knockdown of α4βδ GABAA receptors increases anxiety response in adulthood.

Sci Rep
2021-10 | Journal article
Contributors: Hui Shen
Source: Self-asserted source
Hui Shen

Two-photon calcium imaging of neuronal and astrocytic responses: the influence of electrical stimulus parameters and calcium signaling mechanisms

Journal of Neural Engineering
2021-08-01 | Journal article | Author
Part of ISSN: 1741-2560
Part of ISSN: 1741-2552
Contributors: Zengguang Ma; Liangpeng Wei; Xiaolang Du; Shaowei Hou; Feng Chen; Qingyan Jiao; Aili Liu; shujing liu; Junsong Wang; Hui Shen
Source: Self-asserted source
Hui Shen

Arctigenin Exerts Neuroprotective Effect by Ameliorating Cortical Activities in Experimental Autoimmune Encephalomyelitis In Vivo.

Front Immunol
2021-07 | Journal article
Contributors: Hui Shen
Source: Self-asserted source
Hui Shen

Two-photon calcium imaging of neuronal and astrocytic responses: the influence of electrical stimulus parameters and calcium signaling mechanisms.

J Neural Eng
2021-07-02 | Journal article
Contributors: Hui Shen
Source: Self-asserted source
Hui Shen

Arctigenin Exerts Neuroprotective Effect By Ameliorating Cortical Activities in Experimental Autoimmune Encephalomyelitis in Vivo

2021-01-25 | Preprint | Author
Contributors: Liangpeng Wei; Zhenyi Xue; Baihui Lan; Shiyang Yuan; Yuanyuan Li; Cunle Guo; Rongxin Zhang; Ran Ding; Hui Shen
Source: Self-asserted source
Hui Shen

Sleep Deprivation Aggravates Cognitive Impairment by the Alteration of Hippocampal Neuronal Activity and the Density of Dendritic Spine in Isoflurane-Exposed Mice

Front Behav Neurosci
2020-11 | Journal article
Contributors: Hui Shen
Source: Self-asserted source
Hui Shen

Increased Dendritic Branching of and Reduced δ-GABAA Receptor Expression on Parvalbumin-Positive Interneurons Increase Inhibitory Currents and Reduce Synaptic Plasticity at Puberty in Female Mouse CA1 Hippocampus

Front Cell Neurosci
2020-07 | Journal article
Contributors: Hui Shen
Source: Self-asserted source
Hui Shen

Ketamine contributes to the alteration of Ca2+ transient evoked by behavioral tests in the prelimbic area of mPFC: A study on chronic CORT-induced depressive mice

Neurosci Lett
2020-06 | Journal article
Contributors: Hui Shen
Source: Self-asserted source
Hui Shen

Simultaneous calcium recordings of hippocampal CA1 and primary motor cortex M1 and their relations to behavioral activities in freely moving epileptic mice

Exp Brain Res
2020-06 | Journal article
Contributors: Hui Shen
Source: Self-asserted source
Hui Shen

ω-3PUFAs Improve Cognitive Impairments Through Ser133 Phosphorylation of CREB Upregulating BDNF/TrkB Signal in Schizophrenia

Neurotherapeutics
2020-05 | Journal article
Contributors: Hui Shen
Source: Self-asserted source
Hui Shen

Transient ischemia-reperfusion induces cortical hyperactivity and AMPAR trafficking in the somatosensory cortex

Aging
2020-03-09 | Journal article
Contributors: Hui Shen
Source: Self-asserted source
Hui Shen

ortical Plasticity Induced by Anodal Transcranial Pulsed Current Stimulation Investigated by Combining Two-Photon Imaging and Electrophysiological Recording

Front Cell Neurosci
2019-08 | Journal article
Contributors: Hui Shen
Source: Self-asserted source
Hui Shen

Stereotypical patterns of epileptiform calcium signal in hippocampal CA1, CA3, dentate gyrus and entorhinal cortex in freely moving mice

Sci Rep
2019-05 | Journal article
Contributors: Hui Shen
Source: Self-asserted source
Hui Shen

α4βδ GABAA Receptors Trigger Synaptic Pruning and Reduce Dendritic Length of Female Mouse CA3 Hippocampal Pyramidal Cells at Puberty

Neuroscience
2019-02 | Journal article
Contributors: Hui Shen
Source: Self-asserted source
Hui Shen

GLYX-13, a NMDA Receptor Glycine-Site Functional Partial Agonist, Attenuates Cerebral Ischemia Injury In Vivo and Vitro by Differential Modulations of NMDA Receptors Subunit Components at Different Post-Ischemia Stage in Mice

Front Aging Neurosci
2017-06 | Journal article
Contributors: Hui Shen
Source: Self-asserted source
Hui Shen

Targeted Patching and Dendritic Ca2+ Imaging in Nonhuman Primate Brain in vivo

Sci Rep
2017-06 | Journal article
Contributors: Hui Shen
Source: Self-asserted source
Hui Shen

α4βδ GABAA receptors reduce dendritic spine density in CA1 hippocampus and impair relearning ability of adolescent female mice: Effects of a GABA agonist and a stress steroid

Neuroscience
2017-04 | Journal article
Contributors: Hui Shen
Source: Self-asserted source
Hui Shen

Role of α4-containing GABAA receptors in limiting synaptic plasticity and spatial learning of female mice during the pubertal period

Brain Res
2017-01 | Journal article
Contributors: Hui Shen
Source: Self-asserted source
Hui Shen

The decrease of NMDAR subunit expression and NMDAR EPSC in hippocampus by neonatal exposure to desflurane in mice

Behav Brain Res
2017-01 | Journal article
Contributors: Hui Shen
Source: Self-asserted source
Hui Shen

GSK-3β inhibitors reverse cocaine-induced synaptic transmission dysfunction in the nucleus accumbens.

Synapse
2016-11 | Journal article
Contributors: Hui Shen
Source: Self-asserted source
Hui Shen

Pubertal Expression of α4βδ GABAA Receptors Reduces Seizure-Like Discharges in CA1 Hippocampus

Sci Rep
2016-08 | Journal article
Contributors: Hui Shen
Source: Self-asserted source
Hui Shen

Synaptic pruning in the female hippocampus is triggered at puberty by extrasynaptic GABAA receptors on dendritic spines

elife
2016-05 | Journal article
Contributors: Hui Shen
Source: Self-asserted source
Hui Shen

Neurosteroid effects at α4βδ GABAA receptors alter spatial learning and synaptic plasticity in CA1 hippocampus across the estrous cycle of the mouse

Brain Res
2015-09 | Journal article
Contributors: Hui Shen
Source: Self-asserted source
Hui Shen

The neuroprotection of liraglutide on Alzheimer-like learning and memory impairment by modulating the hyperphosphorylation of tau and neurofilament proteins and insulin signaling pathways in mice

Alzheimers Di
2013 | Journal article
Contributors: Hui Shen
Source: Self-asserted source
Hui Shen

A stress steroid triggers anxiety via increased expression of α4βδ GABAA receptors in methamphetamine dependence

Neuroscience
2013-12 | Journal article
Contributors: Hui Shen
Source: Self-asserted source
Hui Shen

Regulation of the surface expression of α4β2δ GABAA receptors by high efficacy states

Brain Res
2012-06 | Journal article
Contributors: Hui Shen
Source: Self-asserted source
Hui Shen

Knockout of the γ-aminobutyric acid receptor subunit α4 reduces functional δ-containing extrasynaptic receptors in hippocampal pyramidal cells at the onset of puberty

Brain Res
2012-04 | Journal article
Contributors: Hui Shen
Source: Self-asserted source
Hui Shen

A critical role for α4βδ GABAA receptors in shaping learning deficits at puberty in mice

Science
2010-03-19 | Journal article
Contributors: Hui Shen
Source: Self-asserted source
Hui Shen

Plasticity of the alpha4betadelta GABAA receptor

Biochem Soc Trans
2009-12 | Journal issue or edition
Contributors: Hui Shen
Source: Self-asserted source
Hui Shen

Puberty, steroids and GABA(A) receptor plasticity

Psychoneuroendocrinology
2009-12 | Journal issue or edition
Contributors: Hui Shen
Source: Self-asserted source
Hui Shen

Neurosteroid regulation of GABA(A) receptors: Focus on the alpha4 and delta subunits

Pharmacol Ther
2007-10 | Journal article
Contributors: Hui Shen
Source: Self-asserted source
Hui Shen

Reversal of neurosteroid effects at α4βδ GABAA receptors triggers anxiety at puberty.

Nature Neuroscience
2007-04 | Journal article
Contributors: Hui Shen
Source: Self-asserted source
Hui Shen

Short-term steroid treatment increases delta GABAA receptor subunit expression in rat CA1 hippocampus: pharmacological and behavioral effects

Neuropharmacology
2005-10 | Journal article
Contributors: Hui Shen
Source: Self-asserted source
Hui Shen

Expression and function of A1 adenosine receptors in the rat hippocampus following transient forebrain ischemia

Neuroscience
2002 | Journal article
Contributors: Hui Shen
Source: Self-asserted source
Hui Shen

A fundamental oscillatory state of isolated rodent hippocampus

J Physiol
2002-04 | Journal article
Contributors: Hui Shen
Source: Self-asserted source
Hui Shen

Upregulation of gap junction connexin 32 with epileptiform activity in the isolated mouse hippocampus

Neuroscience
2001 | Journal article
Contributors: Hui Shen
Source: Self-asserted source
Hui Shen

Peer review (2 reviews for 2 publications/grants)

Review activity for Molecular neurobiology. (1)
Review activity for Nature communications (1)