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Scopus Author ID: 55847970000
SciProfiles: 639936

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Education and qualifications (1)

University of Mississippi Medical Center: Jackson, MS, US

2012-08-13 to 2017-08-11 | Ph.D (Pharmacology and Toxicology)
Education
Source: Self-asserted source
Xiaochen He

Funding (1)

Effect of cell specific PD-1 inhibition on cardiac toxicity

2023-01-01 to 2024-12-31 | Grant
American Heart Association (Dallas, US)
DOI: 10.58275/AHA.23POST1029902.pc.gr.161201
GRANT_NUMBER:

23POST1029902
Source: check_circle
American Heart Association

Works (26)

TIGAR Deficiency Blunts Angiotensin-II-Induced Cardiac Hypertrophy in Mice

International Journal of Molecular Sciences
2024-02 | Journal article | Author
DOI: 10.3390/ijms25042433
Contributors: Xiaochen He; Quinesha A. Williams; Aubrey Cantrell; Jessie Besanson; Heng Zeng; Jian-Xiong Chen
Source: check_circle
Multidisciplinary Digital Publishing Institute

Regulatory role of TIGAR on endothelial metabolism and angiogenesis

Journal of Cellular Physiology
2021 | Journal article
DOI: 10.1002/jcp.30401
EID:

2-s2.0-85105222679

Part of ISSN: 10974652 00219541
Contributors: He, X.; Zeng, H.; Cantrell, A.C.; Chen, J.-X.
Source: Self-asserted source
Xiaochen He via Scopus - Elsevier

Sirtuin 3 alleviates diabetic cardiomyopathy by regulating tigar and cardiomyocyte metabolism

Journal of the American Heart Association
2021 | Journal article
DOI: 10.1161/JAHA.120.018913
EID:

2-s2.0-85102536045

Part of ISSN: 20479980
Contributors: Li, L.; Zeng, H.; He, X.; Chen, J.-X.
Source: Self-asserted source
Xiaochen He via Scopus - Elsevier

A mutation in γ-adducin impairs autoregulation of renal blood flow and promotes the development of kidney disease

Journal of the American Society of Nephrology
2020 | Journal article
DOI: 10.1681/ASN.2019080784
EID:

2-s2.0-85082881644

Part of ISSN: 15333450 10466673
Contributors: Fan, F.; Geurts, A.M.; Pabbidi, M.R.; Ge, Y.; Zhang, C.; Wang, S.; Liu, Y.; Gao, W.; Guo, Y.; Li, L. et al.
Source: Self-asserted source
Xiaochen He via Scopus - Elsevier

A sex-specific role of endothelial sirtuin 3 on blood pressure and diastolic dysfunction in female mice

International Journal of Molecular Sciences
2020 | Journal article
DOI: 10.3390/ijms21249744
EID:

2-s2.0-85098323669

Part of ISSN: 14220067 16616596
Contributors: Zeng, H.; He, X.; Chen, J.
Source: Self-asserted source
Xiaochen He via Scopus - Elsevier

Endothelial prolyl hydroxylase 2 is necessary for angiotensin II-mediated renal fibrosis and injury

American Journal of Physiology - Renal Physiology
2020 | Journal article
DOI: 10.1152/ajprenal.00032.2020
EID:

2-s2.0-85089301669

Part of ISSN: 15221466 03636127
Contributors: Zhao, Y.; Zeng, H.; Liu, B.; He, X.; Chen, J.-X.
Source: Self-asserted source
Xiaochen He via Scopus - Elsevier

Endothelial sirtuin 3 dictates glucose transport to cardiomyocyte and sensitizes pressure overload-induced heart failure

Journal of the American Heart Association
2020 | Journal article
DOI: 10.1161/JAHA.120.015895
EID:

2-s2.0-85085904039

Part of ISSN: 20479980
Contributors: Zeng, H.; He, X.; Chen, J.-X.
Source: Self-asserted source
Xiaochen He via Scopus - Elsevier

Histone acetyltransferase p300 inhibitor improves coronary flow reserve in sirt3 (Sirtuin 3) knockout mice

Journal of the American Heart Association
2020 | Journal article
DOI: 10.1161/JAHA.120.017176
EID:

2-s2.0-85091125203

Part of ISSN: 20479980
Contributors: Su, H.; Zeng, H.; He, X.; Zhu, S.-H.; Chen, J.-X.
Source: Self-asserted source
Xiaochen He via Scopus - Elsevier

SIRT3 Deficiency Sensitizes Angiotensin-II-Induced Renal Fibrosis

Cells
2020 | Journal article
DOI: 10.3390/cells9112510
EID:

2-s2.0-85096817065

Part of ISSN: 20734409
Contributors: Feng, X.; Su, H.; He, X.; Chen, J.-X.; Zeng, H.
Source: Self-asserted source
Xiaochen He via Scopus - Elsevier

Emerging role of SIRT3 in endothelial metabolism, angiogenesis, and cardiovascular disease

Journal of Cellular Physiology
2019 | Journal article
DOI: 10.1002/jcp.27200
EID:

2-s2.0-85052662848

Part of ISSN: 10974652 00219541
Contributors: He, X.; Zeng, H.; Chen, J.-X.
Source: Self-asserted source
Xiaochen He via Scopus - Elsevier

Knockout of dual-specificity protein phosphatase 5 protects against hypertension-induced renal injury

Journal of Pharmacology and Experimental Therapeutics
2019 | Journal article
DOI: 10.1124/jpet.119.258954
EID:

2-s2.0-85070025580

Part of ISSN: 15210103 00223565
Contributors: Zhang, C.; He, X.; Murphy, S.R.; Zhang, H.; Wang, S.; Ge, Y.; Gao, W.; Williams, J.M.; Geurts, A.M.; Roman, R.J. et al.
Source: Self-asserted source
Xiaochen He via Scopus - Elsevier

Visualization of the intrarenal distribution of capillary blood flow

Physiological Reports
2019 | Journal article
DOI: 10.14814/phy2.14065
EID:

2-s2.0-85065015869

Part of ISSN: 2051817X
Contributors: Fan, L.; Wang, S.; He, X.; Gonzalez-Fernandez, E.; Lechene, C.; Fan, F.; Roman, R.J.
Source: Self-asserted source
Xiaochen He via Scopus - Elsevier

Conflicting roles of 20-HETE in hypertension and renal end organ damage

European Journal of Pharmacology
2018 | Journal article
DOI: 10.1016/j.ejphar.2018.06.010
EID:

2-s2.0-85048349138

Part of ISSN: 18790712 00142999
Contributors: Zhang, C.; Booz, G.W.; Yu, Q.; He, X.; Wang, S.; Fan, F.
Source: Self-asserted source
Xiaochen He via Scopus - Elsevier

Enhanced renal ischemia-reperfusion injury in aging and diabetes

American Journal of Physiology - Renal Physiology
2018 | Journal article
DOI: 10.1152/AJPRENAL.00184.2018
EID:

2-s2.0-85061136265

Part of ISSN: 15221466 03636127
Contributors: Muroya, Y.; He, X.; Fan, L.; Wang, S.; Xu, R.; Fan, F.; Roman, R.J.
Source: Self-asserted source
Xiaochen He via Scopus - Elsevier

Inhibition of prolyl hydroxylases alters cell metabolism and reverses pre-existing diastolic dysfunction in mice

International Journal of Cardiology
2018 | Journal article
DOI: 10.1016/j.ijcard.2018.08.065
EID:

2-s2.0-85052728581

Part of ISSN: 18741754 01675273
Contributors: He, X.; Zeng, H.; Roman, R.J.; Chen, J.-X.
Source: Self-asserted source
Xiaochen He via Scopus - Elsevier

Ablation of endothelial prolyl hydroxylase domain protein-2 promotes renal vascular remodelling and fibrosis in mice

Journal of Cellular and Molecular Medicine
2017 | Journal article
DOI: 10.1111/jcmm.13117
EID:

2-s2.0-85014581548

Part of ISSN: 15821838
Contributors: Wang, S.; Zeng, H.; Chen, S.T.; Zhou, L.; Xie, X.-J.; He, X.; Tao, Y.-K.; Tuo, Q.-H.; Deng, C.; Liao, D.-F. et al.
Source: Self-asserted source
Xiaochen He via Scopus - Elsevier

Endothelial specific SIRT3 deletion impairs glycolysis and angiogenesis and causes diastolic dysfunction

Journal of Molecular and Cellular Cardiology
2017 | Journal article
DOI: 10.1016/j.yjmcc.2017.09.007
EID:

2-s2.0-85029808022

Part of ISSN: 10958584 00222828
Contributors: He, X.; Zeng, H.; Chen, S.T.; Roman, R.J.; Aschner, J.L.; Didion, S.; Chen, J.-X.
Source: Self-asserted source
Xiaochen He via Scopus - Elsevier

Notch3 deficiency impairs coronary microvascular maturation and reduces cardiac recovery after myocardial ischemia

International Journal of Cardiology
2017 | Journal article
DOI: 10.1016/j.ijcard.2017.01.096
EID:

2-s2.0-85010495374

Part of ISSN: 18741754 01675273
Contributors: Tao, Y.-K.; Zeng, H.; Zhang, G.-Q.; Chen, S.T.; Xie, X.-J.; He, X.; Wang, S.; Wen, H.; Chen, J.-X.
Source: Self-asserted source
Xiaochen He via Scopus - Elsevier

Ablation of SIRT3 causes coronary microvascular dysfunction and impairs cardiac recovery post myocardial ischemia

International Journal of Cardiology
2016 | Journal article
DOI: 10.1016/j.ijcard.2016.04.092
EID:

2-s2.0-84966269124

Part of ISSN: 18741754 01675273
Contributors: He, X.; Zeng, H.; Chen, J.-X.
Source: Self-asserted source
Xiaochen He via Scopus - Elsevier

Loss of prolyl hydroxylase domain protein 2 in vascular endothelium increases pericyte coverage and promotes pulmonary arterial remodeling

Oncotarget
2016 | Journal article
DOI: 10.18632/oncotarget.11585
EID:

2-s2.0-84991407908

Part of ISSN: 19492553
Contributors: Wang, S.; Zeng, H.; Xie, X.-J.; Tao, Y.-K.; He, X.; Roman, R.J.; Aschner, J.L.; Chen, J.-X.
Source: Self-asserted source
Xiaochen He via Scopus - Elsevier

LPS causes pericyte loss and microvascular dysfunction via disruption of Sirt3/angiopoietins/Tie-2 and HIF-2α/Notch3 pathways

Scientific Reports
2016 | Journal article
DOI: 10.1038/srep20931
EID:

2-s2.0-84958213599

Part of ISSN: 20452322
Contributors: Zeng, H.; He, X.; Tuo, Q.-H.; Liao, D.-F.; Zhang, G.-Q.; Chen, J.-X.
Source: Self-asserted source
Xiaochen He via Scopus - Elsevier

High-fat diet induces cardiac remodelling and dysfunction: Assessment of the role played by SIRT3 loss

Journal of Cellular and Molecular Medicine
2015 | Journal article
DOI: 10.1111/jcmm.12556
EID:

2-s2.0-84929011194

Part of ISSN: 15821838
Contributors: Zeng, H.; Vaka, V.R.; He, X.; Booz, G.W.; Chen, J.-X.
Source: Self-asserted source
Xiaochen He via Scopus - Elsevier

Sirt3 is essential for apelin-induced angiogenesis in post-myocardial infarction of diabetes

Journal of Cellular and Molecular Medicine
2015 | Journal article
DOI: 10.1111/jcmm.12453
EID:

2-s2.0-84921536410

Part of ISSN: 15821838
Contributors: Hou, X.; Zeng, H.; He, X.; Chen, J.-X.
Source: Self-asserted source
Xiaochen He via Scopus - Elsevier

Apelin gene therapy increases myocardial vascular density and ameliorates diabetic cardiomyopathy via upregulation of sirtuin 3

American Journal of Physiology - Heart and Circulatory Physiology
2014 | Journal article
DOI: 10.1152/ajpheart.00821.2013
EID:

2-s2.0-84894047561

Part of ISSN: 03636135 15221539
Contributors: Zeng, H.; He, X.; Hou, X.; Li, L.; Chen, J.-X.
Source: Self-asserted source
Xiaochen He via Scopus - Elsevier

Myocardial Injection of Apelin-Overexpressing Bone Marrow Cells Improves Cardiac Repair via Upregulation of Sirt3 after Myocardial Infarction

PLoS ONE
2013 | Journal article
DOI: 10.1371/journal.pone.0071041
EID:

2-s2.0-84883615107

Part of ISSN: 19326203
Contributors: Li, L.; Zeng, H.; Hou, X.; He, X.; Chen, J.-X.
Source: Self-asserted source
Xiaochen He via Scopus - Elsevier

Early superoxide scavenging accelerates renal microvascular rarefaction and damage in the stenotic kidney

American Journal of Physiology - Renal Physiology
2012 | Journal article
DOI: 10.1152/ajprenal.00154.2012
EID:

2-s2.0-84865132929

Part of ISSN: 03636127 15221466
Contributors: Kelsen, S.; He, X.; Chade, A.R.
Source: Self-asserted source
Xiaochen He via Scopus - Elsevier
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