Personal information

United Kingdom

Biography

Periklis (Laki) Pantazis is the Director of the Imperial College London and LEICA Microsystems Imaging Hub and a Reader in Advanced Optical Precision Imaging (equiv. Associate Professor) at the Department of Bioengineering at Imperial College London.

He studied Biochemistry at the Leibniz University of Hannover, Hannover/Germany followed by a PhD in Biology and Bioengineering at the Max Planck Institute of Molecular Cell Biology and Genetics in Dresden/Germany.

He pursued then postdoctoral studies at the California Institute of Technology/Pasadena/CA/USA before joining as an Assistant Professor the ETH Zurich Department of Biosystems Science and Engineering in Basel/Switzerland.

In 2018/2019, he established his Laboratory of Advanced Optical Precision Imaging at Imperial College London that conceives and applies cutting-edge imaging technologies, assays and reagents for the mechanistic dissecting of development, disease progression and tissue regeneration. Notable contributions are primed conversion (3D precise and nontoxic labelling using), GenEPi (mechanical force sensor reporting Piezo1 function) and bioharmonophores (biocompatible/biodegradable nonlinear imaging probes). His team fosters interdisciplinary projects in the fields of Developmental and Stem Cell Biology, Engineering, Chemistry and Optics and has secured more than a dozen active/pending patents.

Activities

Employment (3)

Imperial College London: London, London, GB

2020-09-01 to present | Director Leica Imaging Hub and Reader in Advanced Optical Precision Imaging (Department of Bioengineering )
Employment
Source: Self-asserted source
Periklis (Laki) Pantazis

Imperial College London: London, London, GB

2018-08-01 to 2020-08-31 | Senior Lecturer (Associate Professor) (Department of Bioengineering)
Employment
Source: Self-asserted source
Periklis (Laki) Pantazis

ETH Zurich: Basel, CH

2011-11-01 to 2018-07-31 | Assistant Professor of Biosystems Analysis (Department of Biosystems Science and Engineering (D-BSSE))
Employment
Source: Self-asserted source
Periklis (Laki) Pantazis

Education and qualifications (3)

California Institute of Technology: Pasadena, CA, US

2006 to 2011 | Postdoctoral Fellow (Biology)
Education
Source: Self-asserted source
Periklis (Laki) Pantazis

Max Planck Institute of Molecular Cell Biology and Genetics: Dresden, DE

2001 to 2005 | PhD (Biology and Bioengineering)
Education
Source: Self-asserted source
Periklis (Laki) Pantazis

Leibniz Universität Hannover: Hannover, Niedersachsen, DE

1995 to 2000 | MS in Biochemistry (Biochemistry)
Education
Source: Self-asserted source
Periklis (Laki) Pantazis

Works (50 of 63)

Items per page:
Page 1 of 2

Fast In Vivo Imaging of SHG Nanoprobes with Multiphoton Light-Sheet Microscopy

ACS Photonics
2020-04-15 | Journal article
Contributors: Guy Malkinson; Pierre Mahou; Élodie Chaudan; Thierry Gacoin; Ali Y. Sonay; Periklis Pantazis; Emmanuel Beaurepaire; Willy Supatto
Source: check_circle
Crossref

GenEPi: Piezo1-based fluorescent reporter for visualizing mechanical stimuli with high spatiotemporal resolution

2019-07-15 | Other
Contributors: Sine Yaganoglu; Nordine Helassa; Benjamin M. Gaub; Maaike Welling; Jian Shi; Daniel J. Müller; Katalin Török; Periklis Pantazis
Source: check_circle
Crossref

Primed Track, high-fidelity lineage tracing in mouse pre-implantation embryos using primed conversion of photoconvertible proteins

eLife
2019-01-21 | Journal article
Contributors: Maaike Welling; Manuel Alexander Mohr; Aaron Ponti; Lluc Rullan Sabater; Andrea Boni; Yumiko K Kawamura; Prisca Liberali; Antoine HFM Peters; Pawel Pelczar; Periklis Pantazis
Source: check_circle
Crossref

Image Correlation Spectroscopy with Second Harmonic Generating Nanoparticles in Suspension and in Cells

The Journal of Physical Chemistry Letters
2018-10-18 | Journal article
Contributors: Eli Slenders; Hannelore Bové; Mathias Urbain; Yannick Mugnier; Ali Yasin Sonay; Periklis Pantazis; Luigi Bonacina; Pieter Vanden Berghe; Martin vandeVen; Marcel Ameloot
Source: check_circle
Crossref

Engineered Photoconvertible Fluorescent Proteins (pcfps) For Primed Conversion

2018-07-19 | Patent
URI:

lens.org/012-671-176-156-758

PAT:

WO 2018/132842 A1

Source: Self-asserted source
Periklis (Laki) Pantazis via The Lens
grade
Preferred source (of 2)‎

Frontispiece: Primed Conversion: The New Kid on the Block for Photoconversion

Chemistry – A European Journal
2018-06-12 | Journal article
Contributors: Manuel Alexander Mohr; Periklis Pantazis
Source: check_circle
Crossref

Primed Conversion: The New Kid on the Block for Photoconversion

Chemistry – A European Journal
2018-06-12 | Journal article
Contributors: Manuel Alexander Mohr; Periklis Pantazis
Source: check_circle
Crossref

Method And Device To Achieve Spatially Confined Photointeraction At The Focal Volume Of A Microscope

2018-05-15 | Patent
URI:

lens.org/035-603-141-709-746

PAT:

US 9971136 B2

Source: Self-asserted source
Periklis (Laki) Pantazis via The Lens
grade
Preferred source (of 2)‎

Biodegradable, Second-harmonic-generating Nanoprobe For Biomedical Imaging Applications

2018-04-05 | Patent
URI:

lens.org/072-480-172-874-458

PAT:

WO 2018/060378 A1

Source: Self-asserted source
Periklis (Laki) Pantazis via The Lens
grade
Preferred source (of 2)‎

Effective Labeling of Primary Somatic Stem Cells with BaTiO3 Nanocrystals for Second Harmonic Generation Imaging

Small
2018-02 | Journal article
Contributors: Nami Sugiyama; Ali Y. Sonay; Roxanne Tussiwand; Bruce E. Cohen; Periklis Pantazis
Source: check_circle
Crossref

Second Harmonic Imaging Nanoprobes And Techniques For Use Thereof

2018-02-20 | Patent
URI:

lens.org/168-186-387-101-27X

PAT:

US 9897587 B2

Source: Self-asserted source
Periklis (Laki) Pantazis via The Lens
grade
Preferred source (of 2)‎

Second Harmonic Imaging Nanoprobes And Techniques For Use Thereof

2018-01-17 | Patent
URI:

lens.org/049-931-151-152-874

PAT:

EP 2092297 A4

Source: Self-asserted source
Periklis (Laki) Pantazis via The Lens
grade
Preferred source (of 2)‎

High fidelity lineage tracing in mouse pre-implantation embryos using primed conversion of photoconvertible proteins

2017-11-12 | Other
Contributors: Maaike Welling; Manuel Alexander Mohr; Aaron Ponti; Lluc Rullan Sabater; Andrea Boni; Prisca Liberali; Pawel Pelczar; Periklis Pantazis
Source: check_circle
Crossref

Monitoring and manipulating cellular crosstalk during kidney fibrosis inside a 3D in vitro co-culture

Scientific Reports
2017-11-03 | Journal article
Contributors: Bramasta Nugraha; Manuel A. Mohr; Aaron Ponti; Maximilian Y. Emmert; Franziska Weibel; Simon P. Hoerstrup; Solange Moll; Ulrich Certa; Marco Prunotto; Periklis Pantazis
Source: check_circle
Crossref

Multipurpose Analysis Using Second Harmonic Generating Nanoprobes

2017-10-25 | Patent
URI:

lens.org/057-203-762-739-951

PAT:

EP 2380019 A4

Source: Self-asserted source
Periklis (Laki) Pantazis via The Lens
grade
Preferred source (of 2)‎

Rational Engineering of Photoconvertible Fluorescent Proteins for Dual‐Color Fluorescence Nanoscopy Enabled by a Triplet‐State Mechanism of Primed Conversion

Angewandte Chemie
2017-09-11 | Journal article
Contributors: Manuel Alexander Mohr; Andrei Yu. Kobitski; Lluc Rullan Sabater; Karin Nienhaus; Christopher John Obara; Jennifer Lippincott‐Schwartz; Gerd Ulrich Nienhaus; Periklis Pantazis
Source: check_circle
Crossref

Rational Engineering of Photoconvertible Fluorescent Proteins for Dual‐Color Fluorescence Nanoscopy Enabled by a Triplet‐State Mechanism of Primed Conversion

Angewandte Chemie International Edition
2017-09-11 | Journal article
Contributors: Manuel Alexander Mohr; Andrei Yu. Kobitski; Lluc Rullan Sabater; Karin Nienhaus; Christopher John Obara; Jennifer Lippincott‐Schwartz; Gerd Ulrich Nienhaus; Periklis Pantazis
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Optogenetic control with a photocleavable protein, PhoCl.

2017-04 | Journal article
Contributors: Zhang W; Lohman AW; Zhuravlova Y; Lu X; Wiens MD; Hoi H; Yaganoglu S; Mohr MA; Kitova EN; Klassen JS et al.
Source: Self-asserted source
Periklis (Laki) Pantazis via Europe PubMed Central

Second Harmonic Imaging Nanoprobes And Techniques For Use Thereof

2017-03-23 | Patent
URI:

lens.org/013-367-711-538-02X

PAT:

US 2017/0082596 A1

Source: Self-asserted source
Periklis (Laki) Pantazis via The Lens
grade
Preferred source (of 2)‎

Single neuron morphology in vivo with confined primed conversion.

2016 | Journal article
Contributors: Mohr MA; Pantazis P
Source: Self-asserted source
Periklis (Laki) Pantazis via Europe PubMed Central

Labeling cellular structures in vivo using confined primed conversion of photoconvertible fluorescent proteins

Nature Protocols
2016-12-03 | Journal article
Contributors: Manuel Alexander Mohr; Paul Argast; Periklis Pantazis
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Second Harmonic Imaging Nanoprobes And Techniques For Use Thereof

2016-10-25 | Patent
URI:

lens.org/013-917-225-928-771

PAT:

US 9476830 B2

Source: Self-asserted source
Periklis (Laki) Pantazis via The Lens
grade
Preferred source (of 2)‎

Functionalization Of And Use Of Functionalized Second Harmonic Generating Nanoprobes

2016-05-31 | Patent
URI:

lens.org/162-785-906-889-000

PAT:

US 9352055 B2

Source: Self-asserted source
Periklis (Laki) Pantazis via The Lens
grade
Preferred source (of 2)‎

Symmetry breaking in the early mammalian embryo: the case for quantitative single-cell imaging analysis.

2016-03 | Journal article
Contributors: Welling M; Ponti A; Pantazis P
Source: Self-asserted source
Periklis (Laki) Pantazis via Europe PubMed Central

Functionalization Of And Use Of Functionalized Second Harmonic Generating Nanoprobes

2016-02-25 | Patent
URI:

lens.org/001-866-942-277-809

PAT:

US 2016/0051705 A1

Source: Self-asserted source
Periklis (Laki) Pantazis via The Lens
grade
Preferred source (of 2)‎

Method And Device To Achieve Spatially Confined Photointeraction At The Focal Volume Of A Microscope

2016-02-25 | Patent
URI:

lens.org/064-746-398-747-537

PAT:

US 2016/0054553 A1

Source: Self-asserted source
Periklis (Laki) Pantazis via The Lens
grade
Preferred source (of 2)‎

Method And Device To Achieve Spatially Confined Photointeraction At The Focal Volume Of A Microscope

2016-01-27 | Patent
URI:

lens.org/188-886-421-187-090

PAT:

EP 2976621 A1

Source: Self-asserted source
Periklis (Laki) Pantazis via The Lens
grade
Preferred source (of 2)‎

Determination of the source of SHG verniers in zebrafish skeletal muscle

Scientific Reports
2015 | Journal article
EID:

2-s2.0-84949659842

Contributors: Dempsey, W.P.; Hodas, N.O.; Ponti, A.; Pantazis, P.
Source: Self-asserted source
Periklis (Laki) Pantazis via Scopus - Elsevier
grade
Preferred source (of 2)‎

In vivo single-cell labeling by confined primed conversion

Nature Methods
2015 | Journal article
EID:

2-s2.0-84934444120

Contributors: Dempsey, W.P.; Georgieva, L.; Helbling, P.M.; Sonay, A.Y.; Truong, T.V.; Haffner, M.; Pantazis, P.
Source: Self-asserted source
Periklis (Laki) Pantazis via Scopus - Elsevier
grade
Preferred source (of 3)‎

Functionalization Of And Use Of Functionalized Second Harmonic Generating Nanoprobes

2015-12-29 | Patent
URI:

lens.org/079-186-321-751-986

PAT:

US 9221919 B2

Source: Self-asserted source
Periklis (Laki) Pantazis via The Lens
grade
Preferred source (of 2)‎

Multipurpose Analysis Using Second Harmonic Generating Nanoprobes

2015-02-03 | Patent
URI:

lens.org/159-079-828-358-733

PAT:

US 8945471 B2

Source: Self-asserted source
Periklis (Laki) Pantazis via The Lens
grade
Preferred source (of 2)‎

In vivo cell tracking using PhOTO zebrafish.

2014 | Journal article
Contributors: Dempsey WP; Qin H; Pantazis P
Source: Self-asserted source
Periklis (Laki) Pantazis via Europe PubMed Central
grade
Preferred source (of 2)‎

Method And Device To Achieve Spatially Confined Photointeraction At The Focal Volume Of A Microscope

2014-09-25 | Patent
URI:

lens.org/045-866-508-054-254

PAT:

WO 2014/147211 A1

Source: Self-asserted source
Periklis (Laki) Pantazis via The Lens
grade
Preferred source (of 2)‎

Advances in whole-embryo imaging: a quantitative transition is underway.

2014-05 | Journal article
Contributors: Pantazis P; Supatto W
Source: Self-asserted source
Periklis (Laki) Pantazis via Europe PubMed Central
grade
Preferred source (of 2)‎

Automated processing of zebrafish imaging data: a survey.

2013-09 | Journal article
Contributors: Mikut R; Dickmeis T; Driever W; Geurts P; Hamprecht FA; Kausler BX; Ledesma-Carbayo MJ; Marée R; Mikula K; Pantazis P et al.
Source: Self-asserted source
Periklis (Laki) Pantazis via Europe PubMed Central
grade
Preferred source (of 2)‎

Functionalization Of And Use Of Functionalized Second Harmonic Generating Nanoprobes

2013-05-30 | Patent
URI:

lens.org/154-151-224-804-255

PAT:

WO 2013/078410 A1

Source: Self-asserted source
Periklis (Laki) Pantazis via The Lens
grade
Preferred source (of 2)‎

Functionalization Of And Use Of Functionalized Second Harmonic Generating Nanoprobes

2013-05-23 | Patent
URI:

lens.org/087-340-675-355-174

PAT:

US 2013/0129628 A1

Source: Self-asserted source
Periklis (Laki) Pantazis via The Lens
grade
Preferred source (of 2)‎

PhOTO zebrafish: a transgenic resource for in vivo lineage tracing during development and regeneration.

2012 | Journal article
Contributors: Dempsey WP; Fraser SE; Pantazis P
Source: Self-asserted source
Periklis (Laki) Pantazis via Europe PubMed Central
grade
Preferred source (of 2)‎

Surface functionalization of barium titanate SHG nanoprobes for in vivo imaging in zebrafish.

2012-09 | Journal article
Contributors: Čulić-Viskota J; Dempsey WP; Fraser SE; Pantazis P
Source: Self-asserted source
Periklis (Laki) Pantazis via Europe PubMed Central
grade
Preferred source (of 2)‎

Transcription factor kinetics and the emerging asymmetry in the early mammalian embryo.

2012-06 | Journal article
Contributors: Pantazis P; Bollenbach T
Source: Self-asserted source
Periklis (Laki) Pantazis via Europe PubMed Central
grade
Preferred source (of 2)‎

Second Harmonic Imaging Nanoprobes And Techniques For Use Thereof

2012-06-07 | Patent
URI:

lens.org/096-898-754-960-38X

PAT:

US 2012/0141981 A1

Source: Self-asserted source
Periklis (Laki) Pantazis via The Lens
grade
Preferred source (of 2)‎

SHG nanoprobes: advancing harmonic imaging in biology.

2012-05 | Journal article
Contributors: Dempsey WP; Fraser SE; Pantazis P
Source: Self-asserted source
Periklis (Laki) Pantazis via Europe PubMed Central
grade
Preferred source (of 2)‎

Erratum: Oct4 kinetics predict cell lineage patterning in the early mammalian embryo (Nature Cell Biology (2011) 13 (117-123))

Nature Cell Biology
2011 | Journal article
EID:

2-s2.0-79952260599

Contributors: Plachta, N.; Bollenbach, T.; Pease, S.; Fraser, S.E.; Pantazis, P.
Source: Self-asserted source
Periklis (Laki) Pantazis via Scopus - Elsevier

Intercellular bridges in vertebrate gastrulation.

2011 | Journal article
Contributors: Caneparo L; Pantazis P; Dempsey W; Fraser SE
Source: Self-asserted source
Periklis (Laki) Pantazis via Europe PubMed Central
grade
Preferred source (of 2)‎

Multipurpose Analysis Using Second Harmonic Generating Nanoprobes

2011-10-26 | Patent
URI:

lens.org/111-865-334-102-988

PAT:

EP 2380019 A2

Source: Self-asserted source
Periklis (Laki) Pantazis via The Lens
grade
Preferred source (of 2)‎

Oct4 kinetics predict cell lineage patterning in the early mammalian embryo.

2011-02 | Journal article
Contributors: Plachta N; Bollenbach T; Pease S; Fraser SE; Pantazis P
Source: Self-asserted source
Periklis (Laki) Pantazis via Europe PubMed Central
grade
Preferred source (of 2)‎

Multipurpose Analysis Using Second Harmonic Generating Nanoprobes

2010-11-25 | Patent
URI:

lens.org/148-090-528-043-869

PAT:

WO 2010/090844 A3

Source: Self-asserted source
Periklis (Laki) Pantazis via The Lens
grade
Preferred source (of 2)‎

Multipurpose Analysis Using Second Harmonic Generating Nanoprobes

2010-09-16 | Patent
URI:

lens.org/029-590-568-818-792

PAT:

US 2010/0233820 A1

Source: Self-asserted source
Periklis (Laki) Pantazis via The Lens
grade
Preferred source (of 2)‎

Second harmonic generating (SHG) nanoprobes for in vivo imaging.

2010-08 | Journal article
Contributors: Pantazis P; Maloney J; Wu D; Fraser SE
Source: Self-asserted source
Periklis (Laki) Pantazis via Europe PubMed Central
grade
Preferred source (of 2)‎

Multipurpose Analysis Using Second Harmonic Generating Nanoprobes

2010-08-12 | Patent
URI:

lens.org/198-781-194-276-959

PAT:

WO 2010/090844 A2

Source: Self-asserted source
Periklis (Laki) Pantazis via The Lens
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