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King's College London profile page

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Loop profile: 420646
Scopus Author ID: 8306420300
Scopus Author ID: 8306420300

Keywords

brain biology, nutrition, behavior, drug discovery

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United Kingdom

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Employment (3)

King's College London: London, GB

2023-04-24
Employment
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King's College London

King's College London - Denmark Hill Campus: London, London, GB

2018-09 to 2020-04 | Postdoctoral Research Associate (Basic and Clinical Neuroscience)
Employment
Source: Self-asserted source
Emiliano Pena-Altamira

Università degli Studi di Bologna: Bologna, Emilia-Romagna, IT

2012-07 to 2018-02 | Postdoctoral Research Associate (Pharmacy and Biotechnology)
Employment
Source: Self-asserted source
Emiliano Pena-Altamira

Education and qualifications (5)

King's College London: London, London, GB

2019-09 to present | Postgraduate Diploma Dietetics (Nutritional Sciences)
Education
Source: Self-asserted source
Emiliano Pena-Altamira

Università degli Studi di Padova: Padova, Veneto, IT

2016-01 to 2016-12 | MSc Human Nutrition (Biomedical science)
Education
Source: Self-asserted source
Emiliano Pena-Altamira

Università degli Studi di Padova: Padova, Veneto, IT

2010-01 to 2010-12 | MSc Science Communication
Education
Source: Self-asserted source
Emiliano Pena-Altamira

Università degli Studi di Bologna: Bologna, Emilia-Romagna, IT

2004-01 to 2007-04 | PhD in Cell Biology and Physiology
Education
Source: Self-asserted source
Emiliano Pena-Altamira

Università degli Studi di Bologna: Bologna, Emilia-Romagna, IT

1998-09 to 2003-07 | BSc/MSc Medical Biotechnology
Education
Source: Self-asserted source
Emiliano Pena-Altamira

Professional activities (1)

Association for Nutrition: London, GB

2018-09 to present | Registered Associate Nutritionist
Service
Source: Self-asserted source
Emiliano Pena-Altamira

Works (30)

Dietary Protein Source Influences Brain Inflammation and Memory in a Male Senescence-Accelerated Mouse Model of Dementia

Molecular Neurobiology
2021-04-09 | Journal article
DOI: 10.1007/s12035-020-02191-y
Contributors: Sabrina Petralla; Cristina Parenti; Valentina Ravaioli; Irene Fancello; Francesca Massenzio; Marco Virgili; Barbara Monti; Emiliano Pena-Altamira
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MRI-guided histology of TDP-43 knock-in mice implicates parvalbumin interneuron loss, impaired neurogenesis and aberrant neurodevelopment in amyotrophic lateral sclerosis-frontotemporal dementia

Brain Communications
2021-04-05 | Journal article | Author
DOI: 10.1093/braincomms/fcab114
SOURCE-WORK-ID:

ce10438c-d8ed-46bc-b5e8-9c83ce865ce3

EID:

2-s2.0-85121973784
Contributors: Ziqiang Lin; Eugene Kim; Mohi Ahmed; Gang Han; Camilla Simmons; Yushi Redhead; Jack Bartlett; Emiliano Pena-Altamira; Isobel Callaghan; Matthew Anthony White et al.
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King's College London

Sarm1 deletion suppresses TDP-43-linked motor neuron degeneration and cortical spine loss.

Acta neuropathologica communications
2019-10 | Journal article
DOI: 10.1186/s40478-019-0800-9
PMID: 31661035
Contributors: White MA; Lin Z; Kim E; Henstridge CM; Pena Altamira E; Hunt CK; Burchill E; Callaghan I; Loreto A; Brown-Wright H et al.
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Emiliano Pena-Altamira via Europe PubMed Central
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Deficiency of Mitochondrial Aspartate-Glutamate Carrier 1 Leads to Oligodendrocyte Precursor Cell Proliferation Defects Both In Vitro and In Vivo

International Journal of Molecular Sciences
2019-09-11 | Journal article
DOI: 10.3390/ijms20184486
Contributors: Sabrina Petralla; Luis Emiliano Peña-Altamira; Eleonora Poeta; Francesca Massenzio; Marco Virgili; Simona Nicole Barile; Luigi Sbano; Emanuela Profilo; Mariangela Corricelli; Alberto Danese et al.
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Crossref
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A Focused Library of Psychotropic Analogues with Neuroprotective and Neuroregenerative Potential.

ACS chemical neuroscience
2018-10 | Journal article
DOI: 10.1021/acschemneuro.8b00242
PMID: 30253086
Contributors: Uliassi E; Peña-Altamira LE; Morales AV; Massenzio F; Petralla S; Rossi M; Roberti M; Martinez Gonzalez L; Martinez A; Monti B et al.
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Emiliano Pena-Altamira via Europe PubMed Central
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Microglial overexpression of fALS-linked mutant SOD1 induces SOD1 processing impairment, activation and neurotoxicity and is counteracted by the autophagy inducer trehalose.

Biochimica et biophysica acta. Molecular basis of disease
2018-10 | Journal article
DOI: 10.1016/j.bbadis.2018.10.013
PMID: 30315929
Contributors: Massenzio F; Peña-Altamira E; Petralla S; Virgili M; Zuccheri G; Miti A; Polazzi E; Mengoni I; Piffaretti D; Monti B
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Emiliano Pena-Altamira via Europe PubMed Central
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Down-regulation of the mitochondrial aspartate-glutamate carrier isoform 1 AGC1 inhibits proliferation and N-acetylaspartate synthesis in Neuro2A cells

Biochimica et Biophysica Acta - Molecular Basis of Disease
2017 | Journal article
DOI: 10.1016/j.bbadis.2017.02.022
EID:

2-s2.0-85018317333
Contributors: Profilo, E.; Peña-Altamira, L.E.; Corricelli, M.; Castegna, A.; Danese, A.; Agrimi, G.; Petralla, S.; Giannuzzi, G.; Porcelli, V.; Sbano, L. et al.
Source: Self-asserted source
Emiliano Pena-Altamira via Scopus - Elsevier

Nutritional and Pharmacological Strategies to Regulate Microglial Polarization in Cognitive Aging and Alzheimer's Disease.

Frontiers in aging neuroscience
2017 | Journal article
DOI: 10.3389/fnagi.2017.00175
PMID: 28638339
PMC: PMC5461295
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Emiliano Pena-Altamira via Europe PubMed Central
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Release of soluble and vesicular purine nucleoside phosphorylase from rat astrocytes and microglia induced by pro-inflammatory stimulation with extracellular ATP via P2X7 receptors.

Neurochemistry international
2017-10 | Journal article
DOI: 10.1016/j.neuint.2017.10.010
PMID: 29061383
Contributors: Peña-Altamira LE; Polazzi E; Giuliani P; Beraudi A; Massenzio F; Mengoni I; Poli A; Zuccarini M; Ciccarelli R; Di Iorio P et al.
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Emiliano Pena-Altamira via Europe PubMed Central
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New tacrine dimers with antioxidant linkers as dual drugs: Anti-Alzheimer's and antiproliferative agents.

European journal of medicinal chemistry
2017-06 | Journal article
DOI: 10.1016/j.ejmech.2017.06.048
PMID: 28728108
Source: Self-asserted source
Emiliano Pena-Altamira via Europe PubMed Central
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Evidence for purine nucleoside phosphorylase (PNP) release from RAT C6 glioma cells.

2017-03 | Journal article
DOI: 10.1111/jnc.14004
PMID: 28251649
Contributors: Giuliani P; Zuccarini M; Buccella S; Peña-Altamira LE; Polazzi E; Virgili M; Monti B; Poli A; Rathbone MP; Di Iorio P et al.
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Emiliano Pena-Altamira via Europe PubMed Central
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Changing paradigm to target microglia in neurodegenerative diseases: From anti-inflammatory strategy to active immunomodulation

Expert Opinion on Therapeutic Targets
2016 | Journal article
DOI: 10.1517/14728222.2016.1121237
EID:

2-s2.0-84949807682
Contributors: Peña-Altamira, E.; Prati, F.; Massenzio, F.; Virgili, M.; Contestabile, A.; Bolognesi, M.L.; Monti, B.
Source: Self-asserted source
Emiliano Pena-Altamira via Scopus - Elsevier

Tacrine-resveratrol fused hybrids as multi-target-directed ligands against Alzheimer's disease.

2016-12 | Journal article
DOI: 10.1016/j.ejmech.2016.12.048
PMID: 28064079
Contributors: Jeřábek J; Uliassi E; Guidotti L; Korábečný J; Soukup O; Sepsova V; Hrabinova M; Kuča K; Bartolini M; Peña-Altamira LE et al.
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Emiliano Pena-Altamira via Europe PubMed Central
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Zinc supplementation in rats impairs hippocampal-dependent memory consolidation and dampens post-traumatic recollection of stressful event.

2016-01 | Journal article
DOI: 10.1016/j.euroneuro.2015.12.041
PMID: 26774280
Contributors: Contestabile A; Peña-Altamira E; Virgili M; Monti B
Source: Self-asserted source
Emiliano Pena-Altamira via Europe PubMed Central
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Neuronal Regulation of Neuroprotective Microglial Apolipoprotein E Secretion in Rat In Vitro Models of Brain Pathophysiology.

2015-08 | Journal article
DOI: 10.1097/NEN.0000000000000222
PMID: 26185969
Contributors: Polazzi E; Mengoni I; Peña-Altamira E; Massenzio F; Virgili M; Petralla S; Monti B
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Emiliano Pena-Altamira via Europe PubMed Central
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Multitarget drug design strategy: quinone-tacrine hybrids designed to block amyloid-β aggregation and to exert anticholinesterase and antioxidant effects.

2014-10 | Journal article
DOI: 10.1021/jm5010804
PMID: 25259726
Contributors: Nepovimova E; Uliassi E; Korabecny J; Peña-Altamira LE; Samez S; Pesaresi A; Garcia GE; Bartolini M; Andrisano V; Bergamini C et al.
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Emiliano Pena-Altamira via Europe PubMed Central
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The transcription factor CCAAT enhancer-binding protein β protects rat cerebellar granule neurons from apoptosis through its transcription-activating isoforms.

2014-01 | Journal article
DOI: 10.1111/ejn.12407
PMID: 24438488
Contributors: Peña-Altamira E; Polazzi E; Moretto E; Lauriola M; Monti B
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Emiliano Pena-Altamira via Europe PubMed Central
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Copper-zinc superoxide dismutase (SOD1) is released by microglial cells and confers neuroprotection against 6-OHDA neurotoxicity.

2013 | Journal article
DOI: 10.1159/000337115
PMID: 22572742
Contributors: Polazzi E; Mengoni I; Caprini M; Peña-Altamira E; Kurtys E; Monti B
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Emiliano Pena-Altamira via Europe PubMed Central
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Histone post-translational modifications in Huntington's and Parkinson's diseases.

2013 | Journal article
DOI: 10.2174/13816128113199990355
PMID: 23448464
Contributors: Peña-Altamira LE; Polazzi E; Monti B
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Emiliano Pena-Altamira via Europe PubMed Central
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MBNL142 and MBNL143 gene isoforms, overexpressed in DM1-patient muscle, encode for nuclear proteins interacting with Src family kinases.

2013 | Journal article
DOI: 10.1038/cddis.2013.291
PMID: 23949219
PMC: PMC3763452
Contributors: Botta A; Malena A; Tibaldi E; Rocchi L; Loro E; Pena E; Cenci L; Ambrosi E; Bellocchi MC; Pagano MA et al.
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Emiliano Pena-Altamira via Europe PubMed Central
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Tissue distribution and metabolism of guanosine in rats following intraperitoneal injection

Journal of Biological Regulators and Homeostatic Agents
2012 | Journal article
EID:

2-s2.0-84859882118
Contributors: Giuliani, P.; Ballerini, P.; Ciccarelli, R.; Buccella, S.; Romano, S.; D'Alimonte, I.; Poli, A.; Beraudi, A.; Peña, E.; Jiang, S. et al.
Source: Self-asserted source
Emiliano Pena-Altamira via Scopus - Elsevier

Tissue distribution and metabolism of guanosine in rats following intraperitoneal injection (Journal of Biological Regulators 26, 1, (51))

Journal of Biological Regulators and Homeostatic Agents
2012 | Journal article
EID:

2-s2.0-84864997034
Contributors: Giuliani, P.; Ballerini, P.; Ciccarelli, R.; Buccella, S.; Romano, S.; D'Alimonte, I.; Poli, A.; Beraudi, A.; Peña, E.; Jiang, S. et al.
Source: Self-asserted source
Emiliano Pena-Altamira via Scopus - Elsevier

Erratum: Transcriptional profiling in the lumbar spinal cord of a mouse model of amyotrophic lateral sclerosis: A role for wild-type superoxide dismutase 1 in sporadic disease? (Journal of Molecular Neuroscience DOI: 10.1007/s12031-010-9332-2)

Journal of Molecular Neuroscience
2010 | Journal article
DOI: 10.1007/s12031-010-9363-8
EID:

2-s2.0-77954539434
Contributors: D'Arrigo, A.; Colavito, D.; Peña-Altamira, E.; Fabris, M.; Dam, M.; Contestabile, A.; Leon, A.
Source: Self-asserted source
Emiliano Pena-Altamira via Scopus - Elsevier

Nitric oxide control of proliferation in nerve cells and in tumor cells of nervous origin.

2010 | Journal article
DOI: 10.2174/138161210790232211
PMID: 20236073
Contributors: Peña-Altamira E; Petazzi P; Contestabile A
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Emiliano Pena-Altamira via Europe PubMed Central
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Transcriptional profiling in the lumbar spinal cord of a mouse model of amyotrophic lateral sclerosis: a role for wild-type superoxide dismutase 1 in sporadic disease?

2010-07 | Journal article
DOI: 10.1007/s12031-010-9332-2
PMID: 20177826
Contributors: D'Arrigo A; Colavito D; Peña-Altamira E; Fabris M; Dam M; Contestabile A; Leon A
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Emiliano Pena-Altamira via Europe PubMed Central
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Neuroprotection of microglial conditioned medium on 6-hydroxydopamine-induced neuronal death: role of transforming growth factor beta-2.

2009-07 | Journal article
DOI: 10.1111/j.1471-4159.2009.06117.x
PMID: 19457129
Contributors: Polazzi E; Altamira LE; Eleuteri S; Barbaro R; Casadio C; Contestabile A; Monti B
Source: Self-asserted source
Emiliano Pena-Altamira via Europe PubMed Central

Long-term dietary administration of valproic acid does not affect, while retinoic acid decreases, the lifespan of G93A mice, a model for amyotrophic lateral sclerosis.

2009-04 | Journal article
DOI: 10.1002/mus.21260
PMID: 19296491
Contributors: Crochemore C; Virgili M; Bonamassa B; Canistro D; Pena-Altamira E; Paolini M; Contestabile A
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Emiliano Pena-Altamira via Europe PubMed Central
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Regional and temporal alterations of ODC/polyamine system during ALS-like neurodegenerative motor syndrome in G93A transgenic mice.

2006-02 | Journal article
DOI: 10.1016/j.neuint.2005.10.004
PMID: 16290266
Contributors: Virgili M; Crochemore C; Peña-Altamira E; Contestabile A
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Emiliano Pena-Altamira via Europe PubMed Central
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Neurochemical correlates of differential neuroprotection by long-term dietary creatine supplementation.

2005-10 | Journal article
DOI: 10.1016/j.brainres.2005.07.011
PMID: 16140286
Contributors: Peña-Altamira E; Crochemore C; Virgili M; Contestabile A
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Emiliano Pena-Altamira via Europe PubMed Central
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Disease-related regressive alterations of forebrain cholinergic system in SOD1 mutant transgenic mice.

2005-04 | Journal article
DOI: 10.1016/j.neuint.2004.12.004
PMID: 15737434
Contributors: Crochemore C; Peña-Altamira E; Virgili M; Monti B; Contestabile A
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Emiliano Pena-Altamira via Europe PubMed Central
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