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Scopus Author ID: 26534503100

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Employment (4)

The Ohio State University: Columbus, Ohio, US

2024-01-01 to present | Associate Professor (Emergency Medicine)
Employment
Source: Self-asserted source
Onur Kanisicak

University of Cincinnati: Cincinnati, OH, US

2018 to present | Assistant Professor (Department of Pathology and Laboratory Medicine)
Employment
Source: Self-asserted source
Onur Kanisicak

Cincinnati Children's Hospital Medical Center: Cincinnati, OH, US

2011 to 2018 | Postdoctoral Research Fellow (Molecular Cardiovascular Biology)
Employment
Source: Self-asserted source
Onur Kanisicak

University of Connecticut: Storrs, CT, US

2005 to 2011 | Graduate Research Assistant (Molecular and Cell Biology)
Employment
Source: Self-asserted source
Onur Kanisicak

Education and qualifications (3)

University of Connecticut: Storrs, CT, US

2005-08-28 to 2011-08-28 | Ph.D. (Molecular and Cellular Biology)
Education
Source: Self-asserted source
Onur Kanisicak

University of Connecticut: Storrs, CT, US

2003-08-28 to 2005-08-28 | M.S. (Molecular and Cell Biology)
Education
Source: Self-asserted source
Onur Kanisicak

İstanbul Üniversitesi Cerrahpaşa Tıp Fakültesi: Istanbul, Istanbul, TR

1997 to 2003-08-28 | B.S. (Biomedical Sciences (TIBBI BIYOLOJIK BILIMLER BOLUMU))
Education
Source: Self-asserted source
Onur Kanisicak

Professional activities (4)

American Society for Matrix Biology: Md., Md., US

2019 to present | Full
Membership
Source: Self-asserted source
Onur Kanisicak

Biomedical Sciences Alumni Council: Istnabul, TR

2018 to present | Full Member
Membership
Source: Self-asserted source
Onur Kanisicak

Society for Developmental Biology: Md., Md., US

2016 to present | Full Member
Membership
Source: Self-asserted source
Onur Kanisicak

American Heart Association: TX, TX, US

2011 to present | Premium Professional
Membership
Source: Self-asserted source
Onur Kanisicak

Funding (5)

Functional and mechanistic delineation of HuR-Wisp1 signaling on myofibroblast activity

2023-06-01 to 2027-05-31 | Grant
National Heart Lung and Blood Institute (Bethesda, US)
URL: https://app.dimensions.ai/details/grant/grant.13518357
GRANT_NUMBER: R01HL166326
Source: Self-asserted source
Onur Kanisicak via DimensionsWizard

Aspergillus fumigatus infection and fibrosis

2021-09-21 to 2026-08-31 | Grant
National Institute of Allergy and Infectious Diseases (Bethesda, US)
URL: https://app.dimensions.ai/details/grant/grant.9844767
GRANT_NUMBER: R01AI159078
Source: Self-asserted source
Onur Kanisicak via DimensionsWizard

Regulators of extracellular matrix production during cardiac development and disease

2020-08-20 to 2025-07-31 | Grant
National Heart Lung and Blood Institute (Bethesda, US)
URL: https://app.dimensions.ai/details/grant/grant.9393586
GRANT_NUMBER: R01HL148598
Source: Self-asserted source
Onur Kanisicak via DimensionsWizard

Deactivating cardiac fibroblasts mediate reverse remodeling upon injury resolution

2018-07-01 to 2021-06-30 | Grant
American Heart Association (New York, US)
URL: https://app.dimensions.ai/details/grant/grant.100067886
GRANT_NUMBER:

18CDA34110117
Source: Self-asserted source
Onur Kanisicak via DimensionsWizard

In vivo characterization and ablation of murine cardiac fibroblasts within normal and pathological heart

2015-07-01 to 2017-06-30 | Grant
American Heart Association (New York, US)
URL: https://app.dimensions.ai/details/grant/grant.100067474
GRANT_NUMBER:

15POST25480009
Source: Self-asserted source
Onur Kanisicak via DimensionsWizard

Works (37)

Etiology of genetic muscle disorders induced by mutations in fast and slow skeletal MyBP-C paralogs

Experimental and Molecular Medicine
2023 | Journal article
DOI: 10.1038/s12276-023-00953-x
EID:

2-s2.0-85149024863

Part of ISSN: 20926413 12263613
Contributors: Song, T.; Landim-Vieira, M.; Ozdemir, M.; Gott, C.; Kanisicak, O.; Pinto, J.R.; Sadayappan, S.
Source: Self-asserted source
Onur Kanisicak via Scopus - Elsevier

HuR inhibition reduces post-ischemic cardiac remodeling by dampening acute inflammatory gene expression and the innate immune response

bioRxiv
2023 | Other
DOI: 10.1101/2023.01.17.524420
EID:

2-s2.0-85150962948

Part of ISSN: 26928205
Contributors: Slone, S.; Anthony, S.R.; Green, L.C.; Nieman, M.L.; Alam, P.; Wu, X.; Roy, S.; Aube, J.; Xu, L.; Lorenz, J.N. et al.
Source: Self-asserted source
Onur Kanisicak via Scopus - Elsevier

HuR-dependent expression of Wisp1 is necessary for TGFβ-induced cardiac myofibroblast activity

Journal of Molecular and Cellular Cardiology
2023 | Journal article
DOI: 10.1016/j.yjmcc.2022.10.007
EID:

2-s2.0-85141982975

Part of ISSN: 10958584 00222828
Contributors: Green, L.C.; Slone, S.; Anthony, S.R.; Guarnieri, A.R.; Parkins, S.; Shearer, S.M.; Nieman, M.L.; Roy, S.; Aube, J.; Wu, X. et al.
Source: Self-asserted source
Onur Kanisicak via Scopus - Elsevier

IL-1β-mediated adaptive reprogramming of endogenous human cardiac fibroblasts to cells with immune features during fibrotic remodeling

Communications Biology
2023 | Journal article
DOI: 10.1038/s42003-023-05463-0
EID:

2-s2.0-85177741535

Part of ISSN: 23993642
Contributors: Siamwala, J.H.; Pagano, F.S.; Dubielecka, P.M.; Ivey, M.J.; Guirao-Abad, J.P.; Zhao, A.; Chen, S.; Granston, H.; Jeong, J.Y.; Rounds, S. et al.
Source: Self-asserted source
Onur Kanisicak via Scopus - Elsevier

Myocardial IGF2R is a critical mediator of inflammation and fibrosis after ischemia-reperfusion injury

bioRxiv
2023 | Other
DOI: 10.1101/2023.04.21.537835
EID:

2-s2.0-85160391783

Part of ISSN: 26928205
Contributors: Wu, Z.; Huang, W.; He, X.; Dutta, S.; Paul, C.; Fan, G.-C.; Kanisicak, O.; Xu, M.; Liang, J.; Wang, Y.
Source: Self-asserted source
Onur Kanisicak via Scopus - Elsevier

Palmitoylation-dependent regulation of cardiomyocyte Rac1 signaling activity and minor effects on cardiac hypertrophy

Journal of Biological Chemistry
2023 | Journal article
DOI: 10.1016/j.jbc.2023.105426
EID:

2-s2.0-85177984199

Part of ISSN: 1083351X 00219258
Contributors: Baldwin, T.A.; Teuber, J.P.; Kuwabara, Y.; Subramani, A.; Lin, S.-C.J.; Kanisicak, O.; Vagnozzi, R.J.; Zhang, W.; Brody, M.J.; Molkentin, J.D.
Source: Self-asserted source
Onur Kanisicak via Scopus - Elsevier

CRISPR activation of endogenous genes reprograms fibroblasts into cardiovascular progenitor cells for myocardial infarction therapy

Molecular Therapy
2022 | Journal article
DOI: 10.1016/j.ymthe.2021.10.015
EID:

2-s2.0-85118560219

Part of ISSN: 15250024 15250016
Contributors: Jiang, L.; Liang, J.; Huang, W.; Ma, J.; Park, K.H.; Wu, Z.; Chen, P.; Zhu, H.; Ma, J.-J.; Cai, W. et al.
Source: Self-asserted source
Onur Kanisicak via Scopus - Elsevier

HuR-dependent expression of Wisp1 is necessary for TGFβ-induced cardiac myofibroblast activity

bioRxiv
2022 | Other
DOI: 10.1101/2022.01.19.476976
EID:

2-s2.0-85125803022

Part of ISSN: 26928205
Contributors: Green, L.C.; Slone, S.; Anthony, S.R.; Aube, J.; Wu, X.; Xu, L.; Kanisicak, O.; Tranter, M.
Source: Self-asserted source
Onur Kanisicak via Scopus - Elsevier

Adipocyte deletion of the RNA binding protein HuR induces cardiac hypertrophy and fibrosis

bioRxiv
2021 | Other
DOI: 10.1101/2021.01.19.425776
EID:

2-s2.0-85102127598

Part of ISSN: 26928205
Contributors: Guarnieri, A.R.; Anthony, S.R.; Gozdiff, A.; Green, L.C.; Slone, S.; Nieman, M.L.; Alam, P.; Benoit, J.B.; Kanisicak, O.; Tranter, M.
Source: Self-asserted source
Onur Kanisicak via Scopus - Elsevier

Adipocyte-specific deletion of HuR induces spontaneous cardiac hypertrophy and fibrosis

American Journal of Physiology - Heart and Circulatory Physiology
2021 | Journal article
DOI: 10.1152/AJPHEART.00957.2020
EID:

2-s2.0-85111119573

Part of ISSN: 15221539 03636135
Contributors: Guarnieri, A.R.; Anthony, S.R.; Gozdiff, A.; Green, L.C.; Fleifil, S.M.; Slone, S.; Nieman, M.L.; Alam, P.; Benoit, J.B.; Owens, A.P. et al.
Source: Self-asserted source
Onur Kanisicak via Scopus - Elsevier

Immunomodulatory effects of mesenchymal stem cells for the treatment of cardiac allograft rejection

Experimental Biology and Medicine
2021 | Journal article
DOI: 10.1177/1535370220978650
EID:

2-s2.0-85097596274

Part of ISSN: 15353699 15353702
Contributors: Wu, Z.; Liang, J.; Huang, W.; Jiang, L.; Paul, C.; Gao, X.; Alam, P.; Kanisicak, O.; Xu, M.; Wang, Y.
Source: Self-asserted source
Onur Kanisicak via Scopus - Elsevier

S-palmitoylation-dependent regulation of cardiomyocyte Rac1 signaling activity and cardiac hypertrophy

bioRxiv
2021 | Other
DOI: 10.1101/2021.05.14.444015
EID:

2-s2.0-85109060908

Part of ISSN: 26928205
Contributors: Brody, M.J.; Baldwin, T.A.; Subramani, A.; Kanisicak, O.; Vagnozzi, R.J.; Molkentin, J.D.
Source: Self-asserted source
Onur Kanisicak via Scopus - Elsevier

Cardiac Remodeling and Repair: Recent Approaches, Advancements, and Future Perspective

International Journal of Molecular Sciences
2021-12 | Journal article | Author
DOI: 10.3390/ijms222313104
Contributors: Perwez Alam; Bryan D. Maliken; Shannon M. Jones; Malina J Ivey; Zhichao Wu; Yigang Wang; Onur Kanisicak
Source: check_circle
Multidisciplinary Digital Publishing Institute
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Characterization of burn eschar pericytes

Journal of Clinical Medicine
2020 | Journal article
DOI: 10.3390/jcm9020606
EID:

2-s2.0-85099240631

Part of ISSN: 20770383
Contributors: Evdokiou, A.; Kanisicak, O.; Gierek, S.; Barry, A.; Ivey, M.J.; Zhang, X.; Bodnar, R.J.; Satish, L.
Source: Self-asserted source
Onur Kanisicak via Scopus - Elsevier

Isolation, Transfection, and Long-Term Culture of Adult Mouse and Rat Cardiomyocytes.

Journal of visualized experiments : JoVE
2020-10 | Journal article
DOI: 10.3791/61073
PMID: 33104067
Contributors: Alam P; Maliken BD; Ivey MJ; Jones SM; Kanisicak O
Source: Self-asserted source
Onur Kanisicak via Europe PubMed Central
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Cell-specific ablation of Hsp47 defines the collagen-producing cells in the injured heart

JCI Insight
2019 | Journal article
DOI: 10.1172/jci.insight.128722
EID:

2-s2.0-85071093116

Part of ISSN: 23793708
Contributors: Khalil, H.; Kanisicak, O.; Vagnozzi, R.J.; Johansen, A.K.; Maliken, B.D.; Prasad, V.; Boyer, J.G.; Brody, M.J.; Schips, T.; Kilian, K.K. et al.
Source: Self-asserted source
Onur Kanisicak via Scopus - Elsevier

Inhibition of Senescence-Associated Genes Rb1 and Meis2 in Adult Cardiomyocytes Results in Cell Cycle Reentry and Cardiac Repair Post–Myocardial Infarction

Journal of the American Heart Association
2019 | Journal article
DOI: 10.1161/JAHA.119.012089
EID:

2-s2.0-85070061580
Contributors: Alam, P.; Haile, B.; Arif, M.; Pandey, R.; Rokvic, M.; Nieman, M.; Maliken, B.D.; Paul, A.; Wang, Y.-G.; Sadayappan, S. et al.
Source: Self-asserted source
Onur Kanisicak via Scopus - Elsevier

Gata4-dependent differentiation of c-Kit<sup>+</sup>-derived endothelial cells underlies artefactual cardiomyocyte regeneration in the heart

Circulation
2018 | Journal article
DOI: 10.1161/CIRCULATIONAHA.118.033703
EID:

2-s2.0-85049270138
Contributors: Maliken, B.D.; Kanisicak, O.; Karch, J.; Khalil, H.; Fu, X.; Boyer, J.G.; Prasad, V.; Zheng, Y.; Molkentin, J.D.
Source: Self-asserted source
Onur Kanisicak via Scopus - Elsevier

Specialized fibroblast differentiated states underlie scar formation in the infarcted mouse heart

Journal of Clinical Investigation
2018 | Journal article
DOI: 10.1172/JCI98215
EID:

2-s2.0-85046402315
Contributors: Fu, X.; Khalil, H.; Kanisicak, O.; Boyer, J.G.; Vagnozzi, R.J.; Maliken, B.D.; Sargent, M.A.; Prasad, V.; Valiente-Alandi, I.; Blaxall, B.C. et al.
Source: Self-asserted source
Onur Kanisicak via Scopus - Elsevier

Van Berlo et al. reply

Nature
2018 | Journal article
DOI: 10.1038/nature25772
EID:

2-s2.0-85044301289
Contributors: Van Berlo, J.H.; Kanisicak, O.; Maillet, M.; Vagnozzi, R.J.; Karch, J.; Lin, S.-C.J.; Middleton, R.C.; Marbán, E.; Molkentin, J.D.
Source: Self-asserted source
Onur Kanisicak via Scopus - Elsevier

Autophagic cell death is dependent on lysosomal membrane permeability through Bax and Bak

eLife
2017-11 | Journal article
DOI: 10.7554/elife.30543
Part of ISSN: 2050-084X
Contributors: Jason Karch; Tobias G Schips; Bryan D Maliken; Matthew J Brody; Michelle A Sargent; Onur Kanisicak; Jeffery D Molkentin
Source: Self-asserted source
Onur Kanisicak via Crossref Metadata Search

BEX1 is an RNA-dependent mediator of cardiomyopathy

Nature Communications
2017-11 | Journal article
DOI: 10.1038/s41467-017-02005-1
Part of ISSN: 2041-1723
Contributors: Federica Accornero; Tobias G. Schips; Jennifer M. Petrosino; Shan-Qing Gu; Onur Kanisicak; Jop H. van Berlo; Jeffery D. Molkentin
Source: Self-asserted source
Onur Kanisicak via Crossref Metadata Search
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Identity Crisis for Regenerative Cardiac cKit+Cells

Circulation Research
2017-10 | Journal article
DOI: 10.1161/circresaha.117.311921
Part of ISSN: 0009-7330
Contributors: Onur Kanisicak; Ronald J. Vagnozzi; Jeffery D. Molkentin
Source: Self-asserted source
Onur Kanisicak via Crossref Metadata Search
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Fibroblast-specific TGF-β–Smad2/3 signaling underlies cardiac fibrosis

Journal of Clinical Investigation
2017-09-11 | Journal article
DOI: 10.1172/jci94753
Part of ISSN: 0021-9738
Contributors: Hadi Khalil; Onur Kanisicak; Vikram Prasad; Robert N. Correll; Xing Fu; Tobias Schips; Ronald J. Vagnozzi; Ruijie Liu; Thanh Huynh; Se-Jin Lee et al.
Source: Self-asserted source
Onur Kanisicak via Crossref Metadata Search
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Preexisting endothelial cells mediate cardiac neovascularization after injury

Journal of Clinical Investigation
2017-06 | Journal article
DOI: 10.1172/jci93868
Part of ISSN: 0021-9738
Contributors: Lingjuan He; Xiuzhen Huang; Onur Kanisicak; Yi Li; Yue Wang; Yan Li; Wenjuan Pu; Qiaozhen Liu; Hui Zhang; Xueying Tian et al.
Source: Self-asserted source
Onur Kanisicak via Crossref Metadata Search
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Applying Modern Transcriptomics to Interrogate the Human Cardiac Fibroblast∗

JACC: Basic to Translational Science
2016 | Journal article
DOI: 10.1016/j.jacbts.2016.10.002
Part of ISSN: 2452-302X
Contributors: Onur Kanisicak; Jeffery D. Molkentin
Source: Self-asserted source
Onur Kanisicak via Crossref Metadata Search
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Thrombospondin expression in myofibers stabilizes muscle membranes

eLife
2016 | Journal article
DOI: 10.7554/eLife.17589
EID:

2-s2.0-84991625071
Contributors: Vanhoutte, D.; Schips, T.G.; Kwong, J.Q.; Davis, J.; Tjondrokoesoemo, A.; Brody, M.J.; Sargent, M.A.; Kanisicak, O.; Yi, H.; Gao, Q.Q. et al.
Source: Self-asserted source
Onur Kanisicak via Scopus - Elsevier

Genetic lineage tracing defines myofibroblast origin and function in the injured heart

Nature Communications
2016-07 | Journal article
DOI: 10.1038/ncomms12260
Part of ISSN: 2041-1723
Contributors: Onur Kanisicak; Hadi Khalil; Malina J. Ivey; Jason Karch; Bryan D. Maliken; Robert N. Correll; Matthew J. Brody; Suh-Chin J. Lin; Bruce J. Aronow; Michelle D. Tallquist et al.
Source: Self-asserted source
Onur Kanisicak via Crossref Metadata Search
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Cathepsin S Contributes to the Pathogenesis of Muscular Dystrophy in Mice

Journal of Biological Chemistry
2016-03-10 | Journal article
DOI: 10.1074/jbc.m116.719054
Part of ISSN: 0021-9258
Contributors: Andoria Tjondrokoesoemo; Tobias G. Schips; Michelle A. Sargent; Davy Vanhoutte; Onur Kanisicak; Vikram Prasad; Suh-Chin J. Lin; Marjorie Maillet; Jeffery D. Molkentin
Source: Self-asserted source
Onur Kanisicak via Crossref Metadata Search
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Genetic overexpression of Serpina3n attenuates muscular dystrophy in mice

Human Molecular Genetics
2016-01-06 | Journal article
DOI: 10.1093/hmg/ddw005
Part of ISSN: 0964-6906
Contributors: Andoria Tjondrokoesoemo; Tobias Schips; Onur Kanisicak; Michelle A. Sargent; Jeffery D. Molkentin
Source: Self-asserted source
Onur Kanisicak via Crossref Metadata Search
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Dissection of thrombospondin-4 domains involved in intracellular adaptive ER Stress responsive signaling

Molecular and Cellular Biology
2015-10 | Journal article
DOI: 10.1128/mcb.00607-15
Part of ISSN: 0270-7306
Contributors: Matthew J. Brody; Tobias G. Schips; Davy Vanhoutte; Onur Kanisicak; Jason Karch; Bryan D. Maliken; N. Scott Blair; Michelle A. Sargent; Vikram Prasad; Jeffery D. Molkentin
Source: Self-asserted source
Onur Kanisicak via Crossref Metadata Search
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Necroptosis Interfaces with MOMP and the MPTP in Mediating Cell Death

PLOS ONE
2015-06-10 | Journal article
DOI: 10.1371/journal.pone.0130520
Part of ISSN: 1932-6203
Contributors: Jason Karch; Onur Kanisicak; Matthew J. Brody; Michelle A. Sargent; Demetria M. Michael; Jeffery D. Molkentin; Dhyan Chandra
Source: Self-asserted source
Onur Kanisicak via Crossref Metadata Search
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Myofiber-specific inhibition of TGFβ signaling protects skeletal muscle from injury and dystrophic disease in mice

Human Molecular Genetics
2014-08-08 | Journal article
DOI: 10.1093/hmg/ddu413
Part of ISSN: 1460-2083
Contributors: Federica Accornero; Onur Kanisicak; Andoria Tjondrokoesoemo; Aria C. Attia; Elizabeth M. McNally; Jeffery D. Molkentin
Source: Self-asserted source
Onur Kanisicak via Crossref Metadata Search
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c-kit+ cells minimally contribute cardiomyocytes to the heart

Nature
2014-05 | Journal article
DOI: 10.1038/nature13309
Part of ISSN: 0028-0836
Contributors: Jop H. van Berlo; Onur Kanisicak; Marjorie Maillet; Ronald J. Vagnozzi; Jason Karch; Suh-Chin J. Lin; Ryan C. Middleton; Eduardo Marbán; Jeffery D. Molkentin
Source: Self-asserted source
Onur Kanisicak via Crossref Metadata Search
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Differential expression of embryonic epicardial progenitor markers and localization of cardiac fibrosis in adult ischemic injury and hypertensive heart disease

Journal of Molecular and Cellular Cardiology
2013 | Journal article
DOI: 10.1016/j.yjmcc.2013.10.005
Part of ISSN: 0022-2828
Contributors: Caitlin M. Braitsch; Onur Kanisicak; Jop H. van Berlo; Jeffery D. Molkentin; Katherine E. Yutzey
Source: Self-asserted source
Onur Kanisicak via Crossref Metadata Search
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Progenitors of skeletal muscle satellite cells express the muscle determination gene, MyoD

Developmental Biology
2009-08 | Journal article
DOI: 10.1016/j.ydbio.2009.05.554
Part of ISSN: 0012-1606
Contributors: Onur Kanisicak; Julio J. Mendez; Shoko Yamamoto; Masakazu Yamamoto; David J. Goldhamer
Source: Self-asserted source
Onur Kanisicak via Crossref Metadata Search
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A multifunctional reporter mouse line for Cre- and FLP-dependent lineage analysis

genesis
2009-02 | Journal article
DOI: 10.1002/dvg.20474
Part of ISSN: 1526-954X
Contributors: Masakazu Yamamoto; Nicole A. Shook; Onur Kanisicak; Shoko Yamamoto; Michael N. Wosczyna; James R. Camp; David J. Goldhamer
Source: Self-asserted source
Onur Kanisicak via Crossref Metadata Search
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Peer review (37 reviews for 11 publications/grants)

Review activity for American Heart Association (7)
Review activity for Analytical chemistry. (1)
Review activity for BMC biology. (1)
Review activity for Cells. (2)
Review activity for Circulation research : (2)
Review activity for Journal of Molecular and Cellular Cardiology. (3)
Review activity for Journal of molecular and cellular cardiology. (7)
Review activity for Life sciences. (3)
Review activity for Molecular medicine. (1)
Review activity for The anatomical record : (2)
Review activity for The FASEB journal : (8)
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