Personal information

Activities

Employment (3)

University of Texas Southwestern Medical Center: Dallas, TX, US

2019-10-07 to present | Assistant Professor (Ophthalmology & Molecular Biology)
Employment
Source: Self-asserted source
Katherine Wert

Stanford University School of Medicine: Palo Alto, CA, US

2017-07-01 to 2019-09-01 | Post-doctoral Scholar (Ophthalmology)
Employment
Source: Self-asserted source
Katherine Wert

Whitehead Institute for Biomedical Research: Cambridge, MA, US

2014-01-01 to 2017-06-30 | Post-doctoral Fellow
Employment
Source: Self-asserted source
Katherine Wert

Education and qualifications (3)

Columbia University Medical Center: New York, NY, US

2009-08 to 2013-10-16 | MPhil and PhD/Nutrition and Metabolic Biology (Institute of Human Nutrition)
Education
Source: Self-asserted source
Katherine Wert

Columbia University Medical Center: New York, NY, US

2008-08 to 2009-08 | M.S. Human Clinical Nutrition (Institute of Human Nutrition)
Education
Source: Self-asserted source
Katherine Wert

Covenant College: Lookout Mountain, GA, US

2004-08 to 2008-05 | B.A. Biomedical Studies
Education
Source: Self-asserted source
Katherine Wert

Funding (1)

A novel in vivo model system of melanoma using a human-mouse neural crest cell chimera

2015-04-01 to 2017-06-30 | Grant
National Cancer Institute (Rockville, US)
GRANT_NUMBER: F32CA196065
Source: Self-asserted source
Katherine Wert via DimensionsWizard

Works (32)

Sensory quiescence induces a cell-non-autonomous integrated stress response curbed by condensate formation of the ATF4 and XRP1 effectors

Nature Communications
2025-01-02 | Journal article
Contributors: Shashank Shekhar; Charles Tracy; Peter V. Lidsky; Raul Andino; Katherine J. Wert; Helmut Krämer
Source: check_circle
Crossref

Human retina-in-a-dish: Unlocking the potential to study mechanisms of inherited retinal disease

Molecular Therapy - Methods & Clinical Development
2023-09 | Journal article
Contributors: Tiffany Yee; Katherine J. Wert
Source: check_circle
Crossref

Long-term progression of retinal degeneration in a preclinical model of CLN7 Batten disease as a baseline for testing clinical therapeutics.

EBioMedicine
2022-10-29 | Journal article
Contributors: Rowe AA; Chen X; Nettesheim ER; Issioui Y; Dong T; Hu Y; Messahel S; Kayani SN; Gray SJ; Wert KJ et al.
Source: Self-asserted source
Katherine Wert

Base and Prime Editing in the Retina-From Preclinical Research toward Human Clinical Trials.

International journal of molecular sciences
2022-10-16 | Journal article
Contributors: Tiffany Yee; Katherine Wert; Wert KJ
Source: Self-asserted source
Katherine Wert

Differential effects of obstructive sleep apnea on the corneal subbasal nerve plexus and retinal nerve fiber layer

PLOS ONE
2022-06-30 | Journal article
Contributors: Katherine A. Bussan; Rayaz A. Malik; Whitney L. Stuard; Natalia Mussi; Won Lee; Jess T. Whitson; Yacine Issioui; Ashley A. Rowe; Katherine J. Wert; Danielle M. Robertson
Source: check_circle
Crossref

Replenishment of TCA cycle intermediates provides photoreceptor resilience against neurodegeneration during progression of retinitis pigmentosa

JCI Insight
2021-09-08 | Journal article
Contributors: Ashley A. Rowe; Pinkal D. Patel; Ruth Gordillo; Katherine J. Wert
Source: check_circle
Crossref

Phenotypic variance in Calpain-5 retinal degeneration

American Journal of Ophthalmology Case Reports
2020-06 | Journal article
Contributors: Peter H. Tang; Teja Chemudupati; Katherine J. Wert; James C. Folk; MaryAnn Mahajan; Stephen H. Tsang; Alexander G. Bassuk; Vinit B. Mahajan
Source: check_circle
Crossref

Metabolite therapy guided by liquid biopsy proteomics delays retinal neurodegeneration

EBioMedicine
2020-02-03 | Journal article
Source: Self-asserted source
Katherine Wert

In vivo expression of mutant calpains in the eye using lentivirus

Methods in Molecular Biology
2019 | Book chapter
EID:

2-s2.0-85059928704

Contributors: Wert, K.J.; Mahajan, V.B.
Source: Self-asserted source
Katherine Wert via Scopus - Elsevier

Inside Back Cover, Volume 40, Issue 12

Human Mutation
2019-12 | Journal article
Contributors: Katherine J. Wert; Susanne F. Koch; Gabriel Velez; Chun‐Wei Hsu; MaryAnn Mahajan; Alexander G. Bassuk; Stephen H. Tsang; Vinit B. Mahajan
Source: check_circle
Crossref

CAPN5 genetic inactivation phenotype supports therapeutic inhibition trials

Human Mutation
2019-12-26 | Journal article
Contributors: Katherine J. Wert; Susanne F. Koch; Gabriel Velez; Chun‐Wei Hsu; MaryAnn Mahajan; Alexander G. Bassuk; Stephen H. Tsang; Vinit B. Mahajan
Source: check_circle
Crossref

Metabolite therapy guided by liquid biopsy proteomics delays retinal neurodegeneration

[]
2019-09-10 | Preprint
Source: Self-asserted source
Katherine Wert

Insights into Retinal Development Using Live Imaging in Female Carriers of Choroideremia.

Ophthalmic surgery, lasers & imaging retina
2019-05-01 | Journal article
Source: Self-asserted source
Katherine Wert

Cytotoxic Escherichia coli strains encoding colibactin isolated from immunocompromised mice with urosepsis and meningitis

PLoS ONE
2018 | Journal article
EID:

2-s2.0-85044234281

Contributors: Bakthavatchalu, V.; Wert, K.J.; Feng, Y.; Mannion, A.; Ge, Z.; Garcia, A.; Scott, K.E.; Caron, T.J.; Madden, C.M.; Jacobsen, J.T. et al.
Source: Self-asserted source
Katherine Wert via Scopus - Elsevier

Establishment of human pluripotent stem cell-derived pancreatic β-like cells in the mouse pancreas

Proceedings of the National Academy of Sciences of the United States of America
2018 | Journal article
EID:

2-s2.0-85045094139

Contributors: Ma, H.; Wert, K.J.; Shvartsman, D.; Melton, D.A.; Jaenisch, R.
Source: Self-asserted source
Katherine Wert via Scopus - Elsevier

Extracellular superoxide dismutase (SOD3) regulates oxidative stress at the vitreoretinal interface

Free Radical Biology and Medicine
2018 | Journal article
EID:

2-s2.0-85049439076

Contributors: Wert, K.J.; Velez, G.; Cross, M.R.; Wagner, B.A.; Teoh-Fitzgerald, M.L.; Buettner, G.R.; McAnany, J.J.; Olivier, A.; Tsang, S.H.; Harper, M.M. et al.
Source: Self-asserted source
Katherine Wert via Scopus - Elsevier

Human neural crest cells contribute to coat pigmentation in interspecies chimeras after in utero injection into mouse embryos

Proceedings of the National Academy of Sciences of the United States of America
2016 | Journal article
EID:

2-s2.0-84957836801

Contributors: Cohen, M.A.; Wert, K.J.; Goldmann, J.; Markoulaki, S.; Buganim, Y.; Fu, D.; Jaenisch, R.
Source: Self-asserted source
Katherine Wert via Scopus - Elsevier

Molecular Criteria for Defining the Naive Human Pluripotent State

Cell Stem Cell
2016 | Journal article
EID:

2-s2.0-84978887267

Contributors: Theunissen, T.W.; Friedli, M.; He, Y.; Planet, E.; O'Neil, R.C.; Markoulaki, S.; Pontis, J.; Wang, H.; Iouranova, A.; Imbeault, M. et al.
Source: Self-asserted source
Katherine Wert via Scopus - Elsevier

Pathology and mechanism of eye diseases

Ophthalmic disease mechanisms and drug discovery
2016 | Book chapter
EID:

2-s2.0-85018962692

Contributors: Wert, K.J.; Kroeger, H.; Wu, F.; Tsang, S.H.; Lin, J.H.
Source: Self-asserted source
Katherine Wert via Scopus - Elsevier

A systematic approach to identify candidate transcription factors that control cell identity

Stem Cell Reports
2015 | Journal article
EID:

2-s2.0-84946716550

Contributors: D'Alessio, A.C.; Fan, Z.P.; Wert, K.J.; Baranov, P.; Cohen, M.A.; Saini, J.S.; Cohick, E.; Charniga, C.; Dadon, D.; Hannett, N.M. et al.
Source: Self-asserted source
Katherine Wert via Scopus - Elsevier

CAPN5 mutation in hereditary uveitis: The R243L mutation increases calpain catalytic activity and triggers intraocular inflammation in a mouse model

Human Molecular Genetics
2015 | Journal article
EID:

2-s2.0-84939501342

Contributors: Wert, K.J.; Bassuk, A.G.; Wu, W.-H.; Gakhar, L.; Coglan, D.; Mahajan, M.; Wu, S.; Yang, J.; Lin, C.-S.; Tsang, S.H. et al.
Source: Self-asserted source
Katherine Wert via Scopus - Elsevier

Functional validation of a human CAPN5 exome variant by lentiviral transduction into mouse retina

Human Molecular Genetics
2014 | Journal article
EID:

2-s2.0-84898793831

Contributors: Wert, K.J.; Skeie, J.M.; Bassuk, A.G.; Olivier, A.K.; Tsang, S.H.; Mahajan, V.B.
Source: Self-asserted source
Katherine Wert via Scopus - Elsevier

General pathophysiology in retinal degeneration

Developments in Ophthalmology
2014 | Book
EID:

2-s2.0-84910060410

Contributors: Wert, K.J.; Lin, J.H.; Tsang, S.H.
Source: Self-asserted source
Katherine Wert via Scopus - Elsevier

General pathophysiology in retinal degeneration

Cell-Based Therapy for Retinal Degenerative Disease
2014 | Book chapter
Part of DOI: 10.1159/000357294
EID:

2-s2.0-84925878338

Contributors: Wert, J.; Lin, J.H.; Tsang, S.H.
Source: Self-asserted source
Katherine Wert via Scopus - Elsevier

Mid-stage intervention achieves similar efficacy as conventional early-stage treatment using gene therapy in a pre-clinical model of retinitis pigmentosa

Human Molecular Genetics
2014 | Journal article
EID:

2-s2.0-84898826569

Contributors: Wert, K.J.; Sancho-Pelluz, J.; Tsang, S.H.
Source: Self-asserted source
Katherine Wert via Scopus - Elsevier

Silencing of tuberin enhances photoreceptor survival and function in a preclinical model of retinitis pigmentosa (an American ophthalmological society thesis)

Transactions of the American Ophthalmological Society
2014 | Journal article
EID:

2-s2.0-84922534728

Contributors: Tsang, S.H.; Chan, L.; Tsai, Y.-T.; Wu, W.-H.; Hsu, C.-W.; Yang, J.; Tosi, J.; Wert, K.J.; Davis, R.J.; Mahajan, V.B.
Source: Self-asserted source
Katherine Wert via Scopus - Elsevier

Gene therapy provides long-term visual function in a pre-clinical model of retinitis pigmentosa

Human Molecular Genetics
2013 | Journal article
EID:

2-s2.0-84872369306

Contributors: Wert, K.J.; Davis, R.J.; Sancho-pelluz, J.; Nishina, P.M.; Tsang, S.H.
Source: Self-asserted source
Katherine Wert via Scopus - Elsevier

Therapeutic margins in a novel preclinical model of retinitis pigmentosa

Journal of Neuroscience
2013 | Journal article
EID:

2-s2.0-84881500484

Contributors: Davis, R.J.; Hsu, C.-W.; Tsai, Y.-T.; Wert, K.J.; Sancho-Pelluz, J.; Lin, C.-S.; Tsang, S.H.
Source: Self-asserted source
Katherine Wert via Scopus - Elsevier

Subretinal injection of gene therapy vectors and stem cells in the perinatal mouse eye.

Journal of visualized experiments : JoVE
2012 | Journal article
EID:

2-s2.0-84873938366

Contributors: Wert, K.J.; Skeie, J.M.; Davis, R.J.; Tsang, S.H.; Mahajan, V.B.
Source: Self-asserted source
Katherine Wert via Scopus - Elsevier

Deoxygenation of aromatic ketones using transfer hydrogenolysis with Raney nickel in 2-propanol

Synthetic Communications
2011 | Journal article
EID:

2-s2.0-79959935656

Contributors: Zuidema, D.R.; Williams, S.L.; Wert, K.J.; Bosma, K.J.; Smith, A.L.; Mebane, R.C.
Source: Self-asserted source
Katherine Wert via Scopus - Elsevier

Novel method of reducing ketones using sodium hydroxide in isopropanol

Synthetic Communications
2010 | Journal article
EID:

2-s2.0-77949363486

Contributors: Zuidema, D.R.; Wert, K.J.; Williams, S.L.; Chill, S.T.; Holte, K.L.; Kokes, N.K.; Mebane, R.C.
Source: Self-asserted source
Katherine Wert via Scopus - Elsevier

Transplantation of reprogrammed embryonic stem cells improves visual function in a mouse model for retinitis pigmentosa

Transplantation
2010 | Journal article
EID:

2-s2.0-77951268630

Contributors: Wang, N.-K.; Tosi, J.; Kasanuki, J.M.; Chou, C.L.; Kong, J.; Parmalee, N.; Wert, K.J.; Allikmets, R.; Lai, C.-C.; Chien, C.-L. et al.
Source: Self-asserted source
Katherine Wert via Scopus - Elsevier