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Scopus Author ID: 6701662163
Scopus Author ID: 6701662163

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Employment (3)

Aarhus University: Aarhus C, DK

Employment
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Aarhus University

Aarhus University: Aarhus, DK

2022-01-01 to present | Associate Professor (Department of Biomedicine)
Employment
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Kathrin Weyer

Aarhus University: Aarhus, DK

2017-07-01 to 2021-12-31 | Assistant Professor (Department of Biomedicine)
Employment
Source: Self-asserted source
Kathrin Weyer

Education and qualifications (1)

Aarhus University: Aarhus, DK

2005-04-01 to 2009-05-09 | PhD (Department of Molecular Biology and Genetics )
Education
Source: Self-asserted source
Kathrin Weyer

Works (39)

Emerging roles of PCSK9 in kidney disease

Pflügers Archiv - European Journal of Physiology
2025-02-18 | Journal article | Author
DOI: 10.1007/s00424-025-03069-5
SOURCE-WORK-ID:

18fb8ec2-9baa-4f07-a575-6e255f48390e

PMID: 39964484
EID:

2-s2.0-85218167541
Contributors: Sandra Hummelgaard; Jean-Claude Kresse; Michael Schou Jensen; Simon Glerup; Kathrin Weyer
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Aarhus University

Lack of renoprotective effects by long-term PCSK9 and SGLT2 inhibition using alirocumab and empagliflozin in obese ZSF1 rats

American journal of physiology. Renal physiology
2025-01 | Journal article | Author
DOI: 10.1152/ajprenal.00065.2024
SOURCE-WORK-ID:

0d3e2b81-4ec1-4381-970b-b5ab4c949b11

PMID: 39556312
EID:

2-s2.0-85212918545
Contributors: Sandra Hummelgaard; Henning Hvid; Henrik Birn; Simon Glerup; Nikola Tom; Mesut Bilgin; Jeppe Egedal Kirchhoff; Kathrin Weyer
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Aarhus University
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Amiloride Reduces Urokinase/Plasminogen-Driven Intratubular Complement Activation in Glomerular Proteinuria

Journal of the American Society of Nephrology
2024-04 | Journal article
DOI: 10.1681/ASN.0000000000000312
Contributors: Gustaf L. Isaksson; Gitte R. Hinrichs; Henrik Andersen; Marie L. Bach; Kathrin Weyer; Rikke Zachar; Jan Erik Henriksen; Kirsten Madsen; Ida K. Lund; Géraldine Mollet et al.
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Crossref
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Filtration and tubular handling of EWE-hC3Nb1, a complement inhibitor nanobody, in wild type mice and a mouse model of proteinuric kidney disease

FEBS Open Bio
2024-02 | Journal article | Author
DOI: 10.1002/2211-5463.13752
SOURCE-WORK-ID:

0ee90f40-6210-4686-a99b-59be41e5c778

PMID: 38124617
EID:

2-s2.0-85181498168
Contributors: Morten Schøler Fast; Kathrin Weyer; Henrik Pedersen; Gregers Rom Andersen; Henrik Birn
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Aarhus University

Megalin-Mediated Endocytosis in the Kidney Proximal Tubule: Relevance to Regulation of the Renal Renin-Angiotensin System

Nephron
2023 | Journal article
DOI: 10.1159/000526369
Contributors: Sandra Hummelgaard; Kathrin Weyer
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Crossref
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Tubular albumin uptake: is there evidence for a quantitatively important, receptor-independent mechanism?

Kidney International
2023-12 | Journal article
DOI: 10.1016/j.kint.2023.07.030
Contributors: Henrik Birn; Rikke Nielsen; Kathrin Weyer
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Crossref
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Proprotein convertase subtilisin/kexin type 9 targets megalin in the kidney proximal tubule and aggravates proteinuria in nephrotic syndrome

Kidney International
2023-10 | Journal article | Author
DOI: 10.1016/j.kint.2023.06.024
SOURCE-WORK-ID:

a863e924-d467-470f-ab7b-82369fdc6c19

PMID: 37406929
EID:

2-s2.0-85168393660
Contributors: Cecilie K Skeby; Sandra Hummelgaard; Camilla Gustafsen; Federica Petrillo; Kathrine P Frederiksen; Ditte Olsen; Tilde Kristensen; Per Ivarsen; Peder Madsen; Erik I Christensen et al.
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Aarhus University

Targeting PCSK9 to tackle cardiovascular disease

Pharmacology & Therapeutics
2023-09 | Journal article | Author
DOI: 10.1016/j.pharmthera.2023.108480
SOURCE-WORK-ID:

1a318d46-fb27-4764-b78e-30000f64a787

PMID: 37331523
EID:

2-s2.0-85165986978
Contributors: Sandra Hummelgaard; Joachim Pold Vilstrup; Camilla Gustafsen; Simon Glerup; Kathrin Weyer
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Aarhus University

Germinal center block exacerbates extrafollicular responses and accelerates autoimmune disease progression in a murine lupus model

bioRxiv
2022 | Other
DOI: 10.1101/2022.03.04.482991
EID:

2-s2.0-85129380971

Part of ISSN: 26928205
Contributors: Voss, L.F.; Howarth, A.J.; Wittenborn, T.R.; Hummelgaard, S.; Juul-Madsen, K.; Kastberg, K.S.; Pedersen, M.K.; Jensen, L.; Papanastasiou, A.D.; Vorup-Jensen, T. et al.
Source: Self-asserted source
Kathrin Weyer via Scopus - Elsevier

The extrafollicular response is sufficient to drive initiation of autoimmunity and early disease hallmarks of lupus

Frontiers in Immunology
2022-12-14 | Journal article | Author
DOI: 10.3389/fimmu.2022.1021370
SOURCE-WORK-ID:

6e5d2edb-bc1a-463d-9d98-41f0940e820d

PMID: 36591222
EID:

2-s2.0-85145075196

PMID: 36591222
Contributors: Lasse F. Voss; Amanda J. Howarth; Thomas Rea Wittenborn; Sandra Hummelgaard; Kristian Juul-Madsen; Kristian S. Kastberg; Mathias K. Pedersen; Lisbeth Jensen; Anastasios D. Papanastasiou; Thomas Vorup-Jensen et al.
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Aarhus University

Distinct functions of megalin and cubilin receptors in recovery of normal and nephrotic levels of filtered albumin

American Journal of Physiology-Renal Physiology
2020-03 | Journal article
DOI: 10.1152/ajprenal.00030.2020
Part of ISSN: 1931-857X
Contributors: Qidong Ren; Kathrin Weyer; Youssef Rbaibi; Kimberly R. Long; Roderick J Tan; Rikke Nielsen; Erik Ilsö Christenssen; Catherine J Baty; Ossama B Kashlan; Ora A. Weisz
Source: Self-asserted source
Kathrin Weyer via Crossref Metadata Search
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Sodium retention by uPA‐plasmin‐ENaC in nephrotic syndrome The authors reply

Acta Physiologica
2019 | Journal article
DOI: 10.1111/apha.13432
Part of ISSN: 1748-1708
Contributors: Gitte R. Hinrichs; Kathrin Weyer; Ulla G. Friis; Per Svenningsen; Ida Katrine Lund; Rikke Nielsen; Géraldine Mollet; Corinne Antignac; Claus Bistrup; Boye L. Jensen et al.
Source: Self-asserted source
Kathrin Weyer via Crossref Metadata Search
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Urokinase‐type plasminogen activator contributes to amiloride‐sensitive sodium retention in nephrotic range glomerular proteinuria in mice

Acta Physiologica
2019-08 | Journal article
DOI: 10.1111/apha.13362
Part of ISSN: 1748-1708
Contributors: Gitte R. Hinrichs; Kathrin Weyer; Ulla G. Friis; Per Svenningsen; Ida Katrine Lund; Rikke Nielsen; Géraldine Mollet; Corinne Antignac; Claus Bistrup; Boye L. Jensen et al.
Source: Self-asserted source
Kathrin Weyer via Crossref Metadata Search
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APOE4-mediated amyloid-β pathology depends on its neuronal receptor LRP1

Journal of Clinical Investigation
2019-02-11 | Journal article
DOI: 10.1172/jci124853
Part of ISSN: 0021-9738
Contributors: Masaya Tachibana; Marie-Louise Holm; Chia-Chen Liu; Mitsuru Shinohara; Tomonori Aikawa; Hiroshi Oue; Yu Yamazaki; Yuka A. Martens; Melissa E. Murray; Patrick M. Sullivan et al.
Source: Self-asserted source
Kathrin Weyer via Crossref Metadata Search
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FP002INCREASED RENAL ABUNDANCY OF CARBONIC ANHYDRASE (CA) 4 IN MEGALIN DEFICIENCY

Nephrology Dialysis Transplantation
2018-05-01 | Journal article
DOI: 10.1093/ndt/gfy104.fp002
Part of ISSN: 0931-0509
Contributors: Anne Brosbøl-Ravnborg; Kathrin Weyer; Erik Christensen; Rikke Nielsen
Source: Self-asserted source
Kathrin Weyer via Crossref Metadata Search

FP016DOWN-REGULATION OF MEGALIN-MEDIATED ENDOCYTOSIS PLAYS A MINOR ROLE IN ANGIOTENSIN II INDUCED PROTEINURIA

Nephrology Dialysis Transplantation
2018-05-01 | Journal article
DOI: 10.1093/ndt/gfy104.fp016
Part of ISSN: 0931-0509
Contributors: Sandra Hummelgaard; Louise Tran; Kasper Schmidt; Erik Christensen; Rikke Nielsen; Henrik Birn; Kathrin Weyer
Source: Self-asserted source
Kathrin Weyer via Crossref Metadata Search

FP021RENAL KNOCKOUT OF THE NEONATAL FC RECEPTOR (FCRN) IS NOT ASSOCIATED WITH CHANGES IN ALBUMIN METABOLISM

Nephrology Dialysis Transplantation
2018-05-01 | Journal article
DOI: 10.1093/ndt/gfy104.fp021
Part of ISSN: 0931-0509
Contributors: Esben Axelgaard; Pia Andersen; Kathrin Weyer; Henrik Birn
Source: Self-asserted source
Kathrin Weyer via Crossref Metadata Search

The Authors Reply

Kidney International
2018-04 | Journal article
DOI: 10.1016/j.kint.2018.01.006
Part of ISSN: 0085-2538
Contributors: Kathrin Weyer; Henrik Birn; Rikke Nielsen; Erik Ilsø Christensen
Source: Self-asserted source
Kathrin Weyer via Crossref Metadata Search
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Abolishment of proximal tubule albumin endocytosis does not affect plasma albumin during nephrotic syndrome in mice

Kidney International
2018-02 | Journal article
DOI: 10.1016/j.kint.2017.07.024
Part of ISSN: 0085-2538
Contributors: Kathrin Weyer; Pia K. Andersen; Kasper Schmidt; Geraldine Mollet; Corinne Antignac; Henrik Birn; Rikke Nielsen; Erik I. Christensen
Source: Self-asserted source
Kathrin Weyer via Crossref Metadata Search
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Heparan sulfate proteoglycans present PCSK9 to the LDL receptor

Nature Communications
2017-09-11 | Journal article
DOI: 10.1038/s41467-017-00568-7
Part of ISSN: 2041-1723
Contributors: Camilla Gustafsen; Ditte Olsen; Joachim Vilstrup; Signe Lund; Anika Reinhardt; Niels Wellner; Torben Larsen; Christian B. F. Andersen; Kathrin Weyer; Jin-ping Li et al.
Source: Self-asserted source
Kathrin Weyer via Crossref Metadata Search
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Megalin dependent urinary cystatin C excretion in ischemic kidney injury in rats

PLOS ONE
2017-06-02 | Journal article
DOI: 10.1371/journal.pone.0178796
Part of ISSN: 1932-6203
Contributors: Danny Jensen; Casper Kierulf-Lassen; Marie Louise Vindvad Kristensen; Rikke Nørregaard; Kathrin Weyer; Rikke Nielsen; Erik Ilsø Christensen; Henrik Birn; Ines Armando
Source: Self-asserted source
Kathrin Weyer via Crossref Metadata Search
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SP163NEPHROTIC RANGE PROTEINURIA AND SODIUM RETENTION IN MICE IS ASSOCIATED WITH INCREASED URINARY PROTEASE ACTIVITY AND ENAC ACTIVATION

Nephrology Dialysis Transplantation
2016-05 | Journal article
DOI: 10.1093/ndt/gfw160.44
Part of ISSN: 1460-2385
Contributors: Gitte R. Hinrichs; Kathrin Weyer; Ulla G. Friis; Rikke Nielsen; Géraldine Mollet; Corinne Antignac; Claus Bistrup; Boye L. Jensen; Henrik Birn
Source: Self-asserted source
Kathrin Weyer via Crossref Metadata Search

Megalin-Mediated Specific Uptake of Chitosan/siRNA Nanoparticles in Mouse Kidney Proximal Tubule Epithelial Cells Enables AQP1 Gene Silencing

Theranostics
2014 | Journal article
DOI: 10.7150/thno.7866
Part of ISSN: 1838-7640
Contributors: Shan Gao; San Hein; Frederik Dagnæs-Hansen; Kathrin Weyer; Chuanxu Yang; Rikke Nielsen; Erik I Christensen; Robert A Fenton; Jørgen Kjems
Source: Self-asserted source
Kathrin Weyer via Crossref Metadata Search
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Papp-a2 modulates development of cranial cartilage and angiogenesis in zebrafish embryos

Development
2014 | Journal article
DOI: 10.1242/dev.119982
Part of ISSN: 0950-1991
Contributors: K. Kjaer-Sorensen; D. H. Engholm; M. R. Jepsen; M. G. Morch; K. Weyer; L. L. Hefting; L. L. Skov; L. S. Laursen; C. Oxvig
Source: Self-asserted source
Kathrin Weyer via Crossref Metadata Search

Pregnancy-associated plasma protein-A2 modulates development of cranial cartilage and angiogenesis in zebrafish embryos

Journal of Cell Science
2014-09-18 | Journal article | Author
DOI: 10.1242/jcs.152587
SOURCE-WORK-ID:

2a5597bb-1ddf-41d0-8295-109e65413865

PMID: 25236600
EID:

2-s2.0-84914140038
Contributors: Kasper Kjaer-Sorensen; Ditte Høyer Engholm; Malene R Jepsen; Maria G Morch; Kathrin Weyer; Louise L Hefting; Louise L Skov; Lisbeth S Laursen; Claus Oxvig
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Aarhus University
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Increased lysosomal proteolysis counteracts protein accumulation in the proximal tubule during focal segmental glomerulosclerosis

Kidney International
2013-11 | Journal article
DOI: 10.1038/ki.2013.218
Part of ISSN: 0085-2538
Contributors: Rikke Nielsen; Geraldine Mollet; Ernie L. Esquivel; Kathrin Weyer; Pia K. Nielsen; Corinne Antignac; Erik I. Christensen
Source: Self-asserted source
Kathrin Weyer via Crossref Metadata Search
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The Authors Reply:

Kidney International
2013-11 | Journal article
DOI: 10.1038/ki.2013.326
Part of ISSN: 0085-2538
Contributors: Rikke Nielsen; Kathrin Weyer; Henrik Birn; Erik I. Christensen
Source: Self-asserted source
Kathrin Weyer via Crossref Metadata Search
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Renal Uptake of 99mTc-Dimercaptosuccinic Acid Is Dependent on Normal Proximal Tubule Receptor-Mediated Endocytosis

Journal of Nuclear Medicine
2012 | Journal article
DOI: 10.2967/jnumed.112.110528
Part of ISSN: 0161-5505
Contributors: K. Weyer; R. Nielsen; S. V. Petersen; E. I. Christensen; M. Rehling; H. Birn
Source: Self-asserted source
Kathrin Weyer via Crossref Metadata Search
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Endocytic Receptors in the Renal Proximal Tubule

Physiology
2012-08 | Journal article
DOI: 10.1152/physiol.00022.2012
Part of ISSN: 1548-9213
Contributors: Erik I. Christensen; Henrik Birn; Tina Storm; Kathrin Weyer; Rikke Nielsen
Source: Self-asserted source
Kathrin Weyer via Crossref Metadata Search
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Generation of Urinary Albumin Fragments Does Not Require Proximal Tubular Uptake

Journal of the American Society of Nephrology
2012-01 | Journal article
DOI: 10.1681/asn.2011101034
Part of ISSN: 1046-6673
Contributors: K. Weyer; R. Nielsen; E. I. Christensen; H. Birn
Source: Self-asserted source
Kathrin Weyer via Crossref Metadata Search
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Mouse model of proximal tubule endocytic dysfunction.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
2011-09 | Journal article
DOI: 10.1093/ndt/gfr525
PMID: 21926402
Contributors: Weyer K; Storm T; Shan J; Vainio S; Kozyraki R; Verroust PJ; Christensen EI; Nielsen R
Source: Self-asserted source
Kathrin Weyer via Europe PubMed Central
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Placental Regulation of Peptide Hormone and Growth Factor Activity by proMBP1

Biology of Reproduction
2011-06-01 | Journal article
DOI: 10.1095/biolreprod.110.090209
Part of ISSN: 0006-3363
Contributors: Kathrin Weyer; Simon Glerup
Source: Self-asserted source
Kathrin Weyer via Crossref Metadata Search
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Lin12-Notch repeat (LNR) modules in regulation of proteolysis

2009 | Dissertation or Thesis | Author
SOURCE-WORK-ID:

0974a66c-3394-4c34-b682-4bda8b73138a
Contributors: Kathrin Weyer
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Aarhus University

A Substrate Specificity-determining Unit of Three Lin12-Notch Repeat Modules Is Formed inTranswithin the Pappalysin-1 Dimer and Requires a Sequence Stretch C-terminal to the Third Module

Journal of Biological Chemistry
2007-02 | Journal article
DOI: 10.1074/jbc.m607903200
Part of ISSN: 0021-9258
Contributors: Kathrin Weyer; Henning B. Boldt; Christine B. Poulsen; Kasper Kjaer-Sorensen; Claus Gyrup; Claus Oxvig
Source: Self-asserted source
Kathrin Weyer via Crossref Metadata Search
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The Lin12-Notch Repeats of Pregnancy-associated Plasma Protein-A Bind Calcium and Determine Its Proteolytic Specificity

Journal of Biological Chemistry
2004-07 | Journal article
DOI: 10.1074/jbc.m405222200
Part of ISSN: 0021-9258
Contributors: Henning B. Boldt; Kasper Kjaer-Sorensen; Michael T. Overgaard; Kathrin Weyer; Christine B. Poulsen; Lars Sottrup-Jensen; Cheryl A. Conover; Linda C. Giudice; Claus Oxvig
Source: Self-asserted source
Kathrin Weyer via Crossref Metadata Search
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Cell surface adhesion of pregnancy-associated plasma protein-A is mediated by four clusters of basic residues located in its third and fourth CCP module

European Journal of Biochemistry
2004-04 | Journal article
DOI: 10.1111/j.1432-1033.2004.04061.x
Part of ISSN: 0014-2956
Contributors: Kathrin Weyer; Michael T. Overgaard; Lisbeth S. Laursen; Claus G. Nielsen; Alexander Schmitz; Michael Christiansen; Lars Sottrup-Jensen; Linda C. Giudice; Claus Oxvig
Source: Self-asserted source
Kathrin Weyer via Crossref Metadata Search
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Cell Surface Targeting of Pregnancy-associated Plasma Protein A Proteolytic Activity

Journal of Biological Chemistry
2002-10-04 | Journal article
DOI: 10.1074/jbc.m209155200
Part of ISSN: 0021-9258
Contributors: Lisbeth S. Laursen; Michael T. Overgaard; Kathrin Weyer; Henning B. Boldt; Peter Ebbesen; Michael Christiansen; Lars Sottrup-Jensen; Linda C. Giudice; Claus Oxvig
Source: Self-asserted source
Kathrin Weyer via Crossref Metadata Search
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Mutational analysis of the proteolytic domain of pregnancy-associated plasma protein-A (PAPP-A): classification as a metzincin

Biochemical Journal
2001-09-01 | Journal article
DOI: 10.1042/bj3580359
Part of ISSN: 0264-6021
Contributors: Henning B. BOLDT; Michael T. OVERGAARD; Lisbeth S. LAURSEN; Kathrin WEYER; Lars SOTTRUP-JENSEN; Claus OXVIG
Source: Self-asserted source
Kathrin Weyer via Crossref Metadata Search

Mutational analysis of the proteolytic domain of pregnancy-associated plasma protein-A (PAPP-A): classification as a metzincin

Biochemical Journal
2001-09-01 | Journal article | Author, Author
SOURCE-WORK-ID:

908e8f65-6b64-43c7-9353-6f88ddea2314

PMID: 11513734
EID:

2-s2.0-0035447508
Contributors: H B Boldt; M T Overgaard; L S Laursen; Kathrin Weyer; L Sottrup-Jensen; C Oxvig
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Aarhus University
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