Personal information

Biography

Doctor, chief physician, professor, doctoral supervisor. He is one of academic and technical leader in Anhui Province. He graduated from Tongji Medical College of Huazhong University of Science and Technology with bachelor's and Doctor's degrees. From 2012 to 2013, he worked as a visiting scholar in the Department of Gastroenterology and Hepatology at Essen University Hospital in Germany. He is good at the diagnosis and treatment of difficult liver diseases, and has established a relatively perfect diagnosis and treatment system for difficult liver diseases and a prediction model for the efficacy of interferon in the treatment of chronic hepatitis B, which provides important reference for clinicians and patients. He presided or participated in more than 10 funds and won the prize of Science and Technology Progress of Anhui Province twice. He has published 50 papers as the first or corresponding author.

Activities

Employment (1)

Second Hospital of Anhui Medical University: Hefei, Anhui, CN

Professor/Chief doctor (Department of Infectious Diseases)
Employment
Source: Self-asserted source
Zhenhua Zhang

Education and qualifications (1)

Huazhong University of Science and Technology: Wuhan, Hubei, CN

Education
Source: Self-asserted source
Zhenhua Zhang

Works (50 of 53)

Items per page:
Page 1 of 2

Suppression of Interferon Response and Antiviral Strategies of Bunyaviruses

Tropical Medicine and Infectious Disease
2024-09 | Journal article | Author
Contributors: Yingying He; Min Shen; Xiaohe Wang; Anqi Yin; Bingyan Liu; Jie Zhu; Zhenhua Zhang
Source: check_circle
Multidisciplinary Digital Publishing Institute

New insights into the role of ribonuclease P protein subunit p30 from tumor to internal reference

Frontiers in Oncology
2022-10-13 | Journal article
Part of ISSN: 2234-943X
Contributors: Zhenhua Zhang; Junchao Wu; Sijie Yu; Yalan Wang; Jie Zhu; Zhenhua Zhang
Source: Self-asserted source
Zhenhua Zhang

Inconsistency analysis between metagenomic next-generation sequencing results of cerebrospinal fluid and clinical diagnosis with suspected central nervous system infection

BMC Infectious Diseases
2022-09-30 | Journal article
Part of ISSN: 1471-2334
Contributors: Zhenhua Zhang; Jin Wang; Jun Ye; Liqi Yang; Xiangfeng Chen; Haoshu Fang; Zhou Liu; Guomei Xia; Yafei Zhang; Zhenhua Zhang
Source: Self-asserted source
Zhenhua Zhang

Establishing reference sequences for each clade of SARS‐CoV‐2 to provide a basis for virus variation and function research

Journal of Medical Virology
2022-04 | Journal article | Author
Part of ISSN: 0146-6615
Part of ISSN: 1096-9071
Contributors: Jian Yu; Shanshan Sun; Qianqian Tang; Chengzhuo Wang; Liangchen Yu; Lulu Ren; Jun Li; Zhenhua Zhang
Source: Self-asserted source
Zhenhua Zhang
grade
Preferred source (of 2)‎

Evaluation of dithiothreitol-oxidizing capacity (DOC) as a serum biomarker for chronic hepatitis B in patients exhibiting normal alanine aminotransferase levels: a pilot study towards better monitoring of disease

eClinicalMedicine
2021-12 | Journal article
Part of ISSN: 2589-5370
Contributors: Zhenhua Zhang; Lumin Yang; Yafei Zhang; Ke Zhang; Zhongping Liu; Tengfei He; Xiaowei Zheng; Lei Li; Elias S J Arnér; Zhenhua Zhang et al.
Source: Self-asserted source
Zhenhua Zhang

Distribution of hepatitis B virus genotypes and subgenotypes

Medicine
2021-12-17 | Journal article
Part of ISSN: 0025-7974
Part of ISSN: 1536-5964
Contributors: Zhenhua Zhang; Zhongping Liu; Yafei Zhang; Mengyuan Xu; Xu Li; Zhenhua Zhang
Source: Self-asserted source
Zhenhua Zhang

A case of COVID-19 with long duration of viral shedding

Journal of Microbiology, Immunology and Infection
2021-02 | Journal article
Part of ISSN: 1684-1182
Contributors: Zhenhua Zhang; Changtai Wang; Mengyuan Xu; Zhenhua Zhang
Source: Self-asserted source
Zhenhua Zhang

Establishment of reference sequences of hepatitis B virus genotype B subgenotypes

Archives of Biological Sciences
2020 | Journal article
Part of ISSN: 0354-4664
Part of ISSN: 1821-4339
Contributors: Zhenhua Zhang; Xiaojun Jin; Qun Cai; Zhenhua Zhang; Jifang Sheng
Source: Self-asserted source
Zhenhua Zhang

Assessing SARS-CoV-2 RNA levels and lymphocyte/T cell counts in COVID-19 patients revealed initial immune status as a major determinant of disease severity

Medical Microbiology and Immunology
2020-12 | Journal article | Author
Part of ISSN: 0300-8584
Part of ISSN: 1432-1831
Contributors: Mingfeng Han; Mengyuan Xu; Yafei Zhang; Zhongping Liu; Shasha Li; Tengfei He; Jinsong Li; Yong Gao; Wanjun Liu; Tuantuan Li et al.
Source: Self-asserted source
Zhenhua Zhang

Discrimination of False Negative Results in RT-PCR Detection of SARS-CoV-2 RNAs in Clinical Specimens by Using an Internal Reference

Virologica Sinica
2020-12 | Journal article | Author
Part of ISSN: 1674-0769
Part of ISSN: 1995-820X
Contributors: Yafei Zhang; Changtai Wang; Mingfeng Han; Jun Ye; Yong Gao; Zhongping Liu; Tengfei He; Tuantuan Li; Mengyuan Xu; Luping Zhou et al.
Source: Self-asserted source
Zhenhua Zhang

Hepatitis B Virus Particles Activate Toll‐Like Receptor 2 Signaling Initially Upon Infection of Primary Human Hepatocytes

Hepatology
2020-09 | Journal article
Part of ISSN: 0270-9139
Part of ISSN: 1527-3350
Contributors: Zhenhua Zhang; Zhenhua Zhang; Martin Trippler; Catherine I. Real; Melanie Werner; Xufeng Luo; Stefan Schefczyk; Thekla Kemper; Olympia E. Anastasiou; Yvonne Ladiges et al.
Source: Self-asserted source
Zhenhua Zhang

The establishment of reference sequence for SARS‐CoV‐2 and variation analysis

Journal of Medical Virology
2020-06 | Journal article | Author
Part of ISSN: 0146-6615
Part of ISSN: 1096-9071
Contributors: Changtai Wang; Zhongping Liu; Zixiang Chen; Xin Huang; Mengyuan Xu; Tengfei He; Zhenhua Zhang
Source: Self-asserted source
Zhenhua Zhang

不同医院无创性肝纤维化指标预测慢性乙型肝炎患者肝纤维化效能差异分析

实用肝脏病杂志
2019 | Journal article
Contributors: Zhenhua Zhang
Source: Self-asserted source
Zhenhua Zhang

A mouse model of subacute liver failure with ascites induced by step-wise increased doses of (-)-epigallocatechin-3-gallate

Scientific Reports
2019-12 | Journal article
Part of ISSN: 2045-2322
Contributors: Zhenhua Zhang; Xiaoxiao Wang; Lumin Yang; Jiajia Wang; Yafei Zhang; Ruixia Dong; Ximing Wu; Chung S. Yang; Zhenhua Zhang; Jinsong Zhang
Source: Self-asserted source
Zhenhua Zhang

Combination therapy based on pegylated interferon alfa improves the therapeutic response of patients with chronic hepatitis B who exhibit high levels of hepatitis B e-antigen at 24 weeks

Medicine
2019-09 | Journal article
Part of ISSN: 0025-7974
Part of ISSN: 1536-5964
Contributors: Zhenhua Zhang; Yafei Zhang; Wei Li; Zhongping Liu; Jun Ye; Guizhou Zou; Zhenhua Zhang; Jiabin Li
Source: Self-asserted source
Zhenhua Zhang

Host Genetic Determinants of Hepatitis B Virus Infection

Frontiers in Genetics
2019-08-13 | Journal article
Part of ISSN: 1664-8021
Contributors: Zhenhua Zhang; Zhenhua Zhang; Changtai Wang; Zhongping Liu; Guizhou Zou; Jun Li; Mengji Lu
Source: Self-asserted source
Zhenhua Zhang

Differences in Cpg Island Distribution Between Subgenotypes of the Hepatitis B Virus Genotype

Medical Science Monitor
2018-09-25 | Journal article
Part of ISSN: 1643-3750
Contributors: Zhenhua Zhang; Lin Chen; Yi Shi; Wanrong Yang; Yafei Zhang; Qinxiu Xie; Yunsong Li; Xu Li; Jun Li; Zhenhua Zhang
Source: Self-asserted source
Zhenhua Zhang

中国慢性HBV感染者基因型分布及其临床意义Meta分析

实用肝脏病杂志
2017 | Magazine article
Contributors: Zhenhua Zhang
Source: Self-asserted source
Zhenhua Zhang

回顾性分析聚乙二醇干扰素治疗HBeAg阳性慢性乙型肝炎患者抗病毒方案调整分析

中华医院感染学杂志
2017 | Journal article
Contributors: Zhenhua Zhang
Source: Self-asserted source
Zhenhua Zhang

Different Mechanisms May Exist for HBsAg Synthesis and Secretion During Various Phases of Chronic Hepatitis B Virus Infection

Medical Science Monitor
2017-03-21 | Journal article
Part of ISSN: 1643-3750
Contributors: Zhenhua Zhang; Yunsong Li; Qun Cai; Qinxiu Xie; Yafei Zhang; Xiangling Meng; Zhenhua Zhang
Source: Self-asserted source
Zhenhua Zhang

High risk of occult hepatitis B virus infection in leukemia patients from China

Archives of Virology
2017-02 | Journal article | Author
Part of ISSN: 0304-8608
Part of ISSN: 1432-8798
Contributors: Zhenhua Zhang; Yafei Zhang; Nan Xu; Cheng Huang; Xu Li; Jun Li
Source: Self-asserted source
Zhenhua Zhang

Genetic variation of hepatitis B virus and its significance for pathogenesis

World Journal of Gastroenterology
2016 | Journal article
Part of ISSN: 1007-9327
Contributors: Zhenhua Zhang; Zhen-Hua Zhang
Source: Self-asserted source
Zhenhua Zhang

Genetic variation of occult hepatitis B virus infection

World Journal of Gastroenterology
2016 | Journal article
Part of ISSN: 1007-9327
Contributors: Zhenhua Zhang; Hui-Lan Zhu; Xu Li; Jun Li; Zhen-Hua Zhang
Source: Self-asserted source
Zhenhua Zhang

Development of algorithms based on serum markers and transient elastography for detecting significant fibrosis and cirrhosis in chronic hepatitis B patients: Significant reduction in liver biopsy

Hepatology Research
2016-12 | Journal article
Part of ISSN: 1386-6346
Contributors: Zhenhua Zhang; Yan Li; Qun Cai; Yafei Zhang; Qinxiu Xie; Nan Xu; Xiaoping Jiang; Jun Li; Xu Li; Zhenhua Zhang
Source: Self-asserted source
Zhenhua Zhang

Occult hepatitis B virus infection: influence of S protein variants

Virology Journal
2016-12 | Journal article
Part of ISSN: 1743-422X
Contributors: Zhenhua Zhang; Zhenhua Zhang; Ling Zhang; Yu Dai; Yafei Zhang; Jun Li; Xu Li
Source: Self-asserted source
Zhenhua Zhang

Prediction model for sustained hepatitis B e antigen seroconversion to peginterferon alfa-2a in chronic hepatitis B

Journal of Gastroenterology and Hepatology
2016-12 | Journal article
Part of ISSN: 0815-9319
Contributors: Zhenhua Zhang; Huilan Zhu; Changtai Wang; Yafei Zhang; Shaofeng Wei; Xu Li; Zhenhua Zhang
Source: Self-asserted source
Zhenhua Zhang

Hepatitis B virus genotype A: design of reference sequences for sub-genotypes

Virus Genes
2016-06 | Journal article
Part of ISSN: 0920-8569
Part of ISSN: 1572-994X
Contributors: Zhenhua Zhang; Qun Cai; Huilan Zhu; Yafei Zhang; Xu Li; Zhenhua Zhang
Source: Self-asserted source
Zhenhua Zhang

Establishment of reference sequences of hepatitis B virus genotype C subgenotypes

Genetics and Molecular Research
2015 | Journal article
Part of ISSN: 1676-5680
Contributors: Zhenhua Zhang; H.L. Zhu; C.T. Wang; J.B. Xia; X. Li; Z.H. Zhang
Source: Self-asserted source
Zhenhua Zhang

Models for predicting hepatitis B e antigen seroconversion in response to interferon-α in chronic hepatitis B patients

World Journal of Gastroenterology
2015 | Journal article
Part of ISSN: 1007-9327
Contributors: Zhenhua Zhang; Chang-Tai Wang
Source: Self-asserted source
Zhenhua Zhang

Occult hepatitis B virus infection among people with a family history of chronic hepatitis B virus infection

Journal of Medical Virology
2015-11 | Journal article
Part of ISSN: 0146-6615
Contributors: Zhenhua Zhang; Zhenhua Zhang; Ling Zhang; Yu Dai; Lei Jin; Binghu Sun; Qian Su; Xu Li
Source: Self-asserted source
Zhenhua Zhang

In vitro and in vivo replication of a chemically synthesized consensus genome of hepatitis B virus genotype B

Journal of Virological Methods
2015-03 | Journal article
Part of ISSN: 0166-0934
Contributors: Zhenhua Zhang; Zhenhua Zhang; Jianbo Xia; Binghu Sun; Yu Dai; Xu Li; Joerg F. Schlaak; Mengji Lu
Source: Self-asserted source
Zhenhua Zhang

Comparison of the antiviral effects of different nucleos(t)ide analogues in chinese patients with chronic hepatitis B: A head-to-head study

Saudi Journal of Gastroenterology
2014 | Journal article
Part of ISSN: 1319-3767
Contributors: Zhenhua Zhang; Xu Li; ZhenHua Zhang; Shu Yu; ChangTai Wang; XiaoGuang Cheng; Qin Zhou; XiaoMiao Zhao; Min Yuan
Source: Self-asserted source
Zhenhua Zhang

HBsAb阳性隐匿性HBV感染者血清、肝组织HBV全基因序列分析

山东医药
2013 | Journal article
Contributors: Zhenhua Zhang
Source: Self-asserted source
Zhenhua Zhang

HBsAg基因变异及其意义

临床肝胆病杂志
2013 | Journal article
Contributors: Zhenhua Zhang
Source: Self-asserted source
Zhenhua Zhang

Polymorphism of estrogen receptor alpha (ESR1) is associated with virological response to entecavir (ETV) in nucleoside-naïve adult patients with chronic hepatitis B

Infection
2013-04 | Journal article
Part of ISSN: 0300-8126
Part of ISSN: 1439-0973
Contributors: Zhenhua Zhang; T.-T. Zhang; J. Ye; S.-L. Xia; Y.-F. Zhang; Q. Su; Z.-H. Zhang; X. Li
Source: Self-asserted source
Zhenhua Zhang

慢性乙型肝炎患者雌激素受体α基因多态性与阿德福韦酯治疗持续性病毒学应答相关性分析

安徽医药
2012 | Journal article
Contributors: Zhenhua Zhang
Source: Self-asserted source
Zhenhua Zhang

隐匿性乙型肝炎病毒感染者血清表面抗体性质鉴定

中华肝脏病杂志
2011 | Magazine article
Contributors: Zhenhua Zhang
Source: Self-asserted source
Zhenhua Zhang

Elimination of hepatitis B virus surface antigen and appearance of neutralizing antibodies in chronically infected patients without viral clearance

Journal of Viral Hepatitis
2011-06 | Journal article
Part of ISSN: 1352-0504
Contributors: Zhenhua Zhang; Z.-H. Zhang; L. Li; X.-P. Zhao; D. Glebe; C. M. Bremer; Z.-M. Zhang; Y.-J. Tian; B.-J. Wang; Y. Yang et al.
Source: Self-asserted source
Zhenhua Zhang

2009年甲型H1N1流感病毒HA区参照序列的建立及变异分析

中华微生物学和免疫学杂志
2010 | Journal article
Contributors: Zhenhua Zhang
Source: Self-asserted source
Zhenhua Zhang

2009甲型H1N1流感病毒神经氨酸酶参照序列的建立及特征分析

中华医院感染学杂志
2010 | Journal article
Contributors: Zhenhua Zhang
Source: Self-asserted source
Zhenhua Zhang

21例危/重症甲型H1N1(2009)流感患者临床特征治疗及转归

安徽医学
2010 | Magazine article
Contributors: Zhenhua Zhang
Source: Self-asserted source
Zhenhua Zhang

护理实习生职业认同感对临床实践的影响

安徽医药
2010 | Magazine article
Contributors: Zhenhua Zhang
Source: Self-asserted source
Zhenhua Zhang

Interleukin-10 gene polymorphisms in association with susceptibility to chronic hepatitis C virus infection: a meta-analysis study

Archives of Virology
2010-11 | Journal article
Part of ISSN: 0304-8608
Part of ISSN: 1432-8798
Contributors: Zhenhua Zhang; Li-Zhou Zhang; Tian-Chen Zhang; Fa-Ming Pan; Zhen-Hua Zhang; Xu Li
Source: Self-asserted source
Zhenhua Zhang

HBsAg和HBsAb双阳性检测结果的初步分析

实用肝脏病杂志
2009 | Magazine article
Contributors: Zhenhua Zhang
Source: Self-asserted source
Zhenhua Zhang

中国乙型肝炎病毒B、C基因型参照序列的建立

中华肝脏病杂志
2009 | Journal article
Contributors: Zhenhua Zhang
Source: Self-asserted source
Zhenhua Zhang

表面抗原和抗体双阳性慢性乙型肝炎病毒感染者病毒S基因的变异分析

中华肝脏病杂志
2009 | Magazine article
Contributors: Zhenhua Zhang
Source: Self-asserted source
Zhenhua Zhang

HBsAg/HBsAb double positive hepatitis B virus infection model in vitro and in vivo

Journal of Huazhong University of Science and Technology [Medical Sciences]
2009-10 | Journal article
Part of ISSN: 1672-0733
Part of ISSN: 1993-1352
Contributors: Zhenhua Zhang; Zhenhua Zhang; Lei Li; Yongjun Tian; Jianbo Xia; Youhua Hao; Xu Li; Mengji Lu; Dongliang Yang
Source: Self-asserted source
Zhenhua Zhang

隐匿性乙型肝炎病毒感染的研究进展

实用肝脏病杂志
2008 | Magazine article
Contributors: Zhenhua Zhang
Source: Self-asserted source
Zhenhua Zhang

土拨鼠肝炎病毒和乙型肝炎病毒的核心蛋白存在共同线性B淋巴细胞表位

中华肝脏病杂志
2007 | Journal article
Contributors: Zhenhua Zhang
Source: Self-asserted source
Zhenhua Zhang

土拨鼠肝炎病毒核心蛋白的高效表达和B细胞表位鉴定

中华微生物学和免疫学杂志
2007 | Magazine article
Contributors: Zhenhua Zhang
Source: Self-asserted source
Zhenhua Zhang
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Peer review (1 review for 1 publication/grant)

Review activity for PLoS neglected tropical diseases (1)